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Bulimia nervosa

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https://www.readbyqxmd.com/read/29455021/effect-of-dopamine-receptor-d4-drd4-haplotypes-on-general-psychopathology-in-patients-with-eating-disorders
#1
Guillermo Gervasini, Luz M González, Carmen Gamero-Villarroel, Sonia Mota-Zamorano, Juan Antonio Carrillo, Isalud Flores, Angustias Garcia-Herráiz
Among the many candidate genes analyzed in eating disorder (ED) patients, those involved in dopaminergic functions may be of special relevance, as dopamine is known to play a significant role in feeding behavior, the distortion of body image, hyperactivity and reward and reinforcement processes. We aimed to determine the effect of functional polymorphisms and haplotypes in the Dopamine Receptor D4 (DRD4) gene on general psychopathological symptoms in ED patients. Two-hundred-and-seventy-three ED patients [199 with Anorexia Nervosa (AN) and 74 with Bulimia Nervosa (BN)] completed the SCL-90R inventory and were genotyped for four functional, clinically relevant DRD4 polymorphisms: three variants in the promoter region [120-bp tandem repeat (TR, long vs...
February 15, 2018: Gene
https://www.readbyqxmd.com/read/29452025/subgrouping-the-users-of-a-specialized-app-for-eating-disorders
#2
Shiri Sadeh-Sharvit, Jane Paik Kim, Alison M Darcy, Eric Neri, Molly Vierhile, Athena Robinson, Jenna Tregarthen, James D Lock
Although mobile technologies for eating disorders (EDs) are burgeoning, there is limited data about the clinical characteristics of individuals using specialized smartphone applications (apps) without accompanying traditional forms of treatment. This study evaluated whether the users of an ED app cluster in clinically meaningful groups. Participants were 1,280 app users (91.3% female; mean age 27) who reported not being in a weekly treatment for their ED. A hierarchical cluster analysis distinguished five groups of participants, all approximating DSM-5 ED categories...
February 16, 2018: Eating Disorders
https://www.readbyqxmd.com/read/29446174/comorbid-depressive-symptoms-and-self-esteem-improve-after-either-cognitive-behavioural-therapy-or-family-based-treatment-for-adolescent-bulimia-nervosa
#3
Fabiola Valenzuela, James Lock, Daniel Le Grange, Cara Bohon
This study examined the effect of family-based treatment for bulimia nervosa (FBT-BN) and cognitive behavioral therapy for adolescents (CBT-A) on depressive symptoms and self-esteem in adolescents with BN. Data were collected from 110 adolescents, ages 12-18, who met Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, text revision criteria for BN or partial BN. Participants were randomly assigned to FBT-BN or CBT-A and completed measures of depressive symptoms and self-esteem before and after treatment and at 6- and 12-month follow-up assessments...
February 15, 2018: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/29445463/resolving-bulimia-nervosa-using-an-innovative-neural-therapy-approach-two-case-reports
#4
Michael I Gurevich, Myung Kyu Chung, Patrick J LaRiccia
Conventional treatment of Bulimia Nervosa is long term, expensive, and often ineffective. Neural therapy holds promise for treating Bulimia Nervosa in a shorter term, lower cost, and more effective manner. Much of neural therapy involves the superficial injection of local anesthetic injections. Implementation into current practice would be feasible.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29437028/changes-in-the-peripheral-endocannabinoid-system-as-a-risk-factor-for-the-development-of-eating-disorders
#5
Anna Capasso, Walter Milano, Omar Cauli
BACKGROUND AND OBJECTIVE: Eating Disorder (ED) is characterized by persistently and severely disturbed eating behaviours. They arise from a combination of long-standing behavioural, emotional, psychological, interpersonal, and social factors and result in insufficient nutrient ingestion and/or adsorption. The three main EDs are: anorexia nervosa, bulimia nervosa, and binge eating disorder. We review the role of peripheral endocannabinoids in eating behaviour. DISCUSSION: The neuronal pathways involved in feeding behaviours are closely related to catecholaminergic, serotoninergic and peptidergic systems...
February 12, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29417609/how-many-individuals-achieve-symptom-abstinence-following-psychological-treatments-for-bulimia-nervosa-a-meta-analytic-review
#6
REVIEW
Jake Linardon, Tracey D Wade
OBJECTIVES: It is unclear how many patients with bulimia nervosa (BN) completely abstain from the core behavioral symptoms after receiving psychological treatment. The present meta-analysis of randomized controlled trials (RCTs) aimed to (a) estimate the prevalence of patients who abstain from binge eating and/or purging following all psychological treatments for BN, and (b) test whether these abstinence estimates are moderated by the type of treatment modality delivered, the definition of abstinence applied, and trial quality...
February 8, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29417593/medical-findings-in-1-026-consecutive-adult-inpatient-residential-eating-disordered-patients
#7
Philip S Mehler, Dan V Blalock, Keegan Walden, Simrat Kaur, Jennifer McBride, Kristine Walsh, Jennifer Watts
OBJECTIVE: Eating disorders are associated with multiple medical complications. We report contemporary medical data, for newly admitted adult inpatient and residential level of care patients. METHOD: Medical records of a transdiagnostic sample of 1,026 patients, with eating disorders, were retrospectively reviewed for the presence of a broad array of medical complications at time of admission. The prevalence of physiologically relevant medical complications was assessed across major eating disorder categories...
February 8, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29415831/evaluation-of-a-short-protocol-for-indirect-calorimetry-in-females-with-eating-disorders-and-healthy-controls
#8
Therese Fostervold Mathisen, Kethe Marie Engen, Jorunn Sundgot-Borgen, Trine Stensrud
BACKGROUND AND AIMS: To enable clinicians to identify the clinical picture and treatment progress and to adjust eating plans according to personal energy needs, it is important to know the patient's correct resting metabolic rate (RMR). Indirect calorimetry (IC) is the preferred method for assessment of RMR, but long duration of measurement increases the load on the patients, and reduces the effectiveness in clinical and scientific settings. Further; not all patients reach a valid RMR according to the suggested best practice protocol, with 5 min of steady state (SS) where respiratory gas volume exchange varies less than 10%...
December 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29413810/transdiagnostic-vs-disorder-focused-perspective-in-children-and-adolescents-with-eating-disorders-findings-from-a-large-multisite-exploratory-study
#9
O Curzio, S Maestro, G Rossi, S Calderoni, L Giombini, S Scardigli, L Dalla Ragione, F Muratori
BACKGROUND: The transdiagnostic model of eating disorders (ED) proposes common cognitive mechanisms in patients with ED psychopathology. Little is known about their role in the maintenance of ED in children and adolescents. This study aimed to determine whether the relationships between key factors (low self-esteem, weight and shape control, clinical perfectionism, interpersonal problems, distress and mood instability) and core maintaining mechanisms (binge-eating and restraint) would support a transdiagnostic theory in young patients...
February 5, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29407005/would-glucagon-like-peptide-1-receptor-agonists-have-efficacy-in-binge-eating-disorder-and-bulimia-nervosa-a-review-of-the-current-literature
#10
Susan L McElroy, Nicole Mori, Anna I Guerdjikova, Paul E Keck
Binge eating, eating an abnormally large amount of food in a discrete period of time with a sense of loss of control over eating, is a defining feature of the eating disorders binge eating disorder (BED) and bulimia nervosa (BN). Both BED and BN are important public health problems for which there are few medical treatments. However, almost all drugs with central nervous system-mediated weight loss properties studied thus far in randomized, placebo-controlled trials in persons with BED or BN have been efficacious for reducing binge eating behavior...
February 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29389338/dietary-assessment-and-counseling-for-dental-erosion
#11
Teresa A Marshall
BACKGROUND AND OVERVIEW: Dental erosion occurs after exposure to intrinsic or extrinsic acids. Exposure to intrinsic gastrointestinal acids is associated with anorexia nervosa, bulimia nervosa, rumination syndrome, or gastroesophageal reflux. Extrinsic dietary acids from foods or beverages also can cause erosion, particularly when exposure is prolonged by holding or swishing behaviors. CONCLUSIONS: Clinicians should screen patients exhibiting dental erosion for anorexia nervosa, bulimia nervosa, rumination syndrome, and gastroesophageal reflux disease...
February 2018: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29384467/speed-of-processing-time-slowing-in-eating-disorders
#12
F Richard Ferraro, Rachel Kramer, Stephanie Weigel
We applied Brinley ( 1965 ) plot analysis to the eating disorders field. Across 23 studies and 165 experimental conditions [experienced by a total of 773 eating disorder (ED) participants, including anorexia nervosa (AN), binge eating (BE), bulimia nervosa (BN), and eating disorders not otherwise specified (EDNOS) and 995 controls], the best-fit regression equation was Y (ED) = 1.08 X (CONTROL) - 31. This equation accounted for 98.2% of the variance. Thus, the ED subjects were only 1.08 times slower than the control subjects, suggesting little processing speed slowing in ED...
January 2018: Journal of General Psychology
https://www.readbyqxmd.com/read/29384460/negative-urgency-and-expectancies-increase-vulnerability-to-binge-eating-in-bulimia-nervosa
#13
Sarah Fischer, Joseph Wonderlich, Lauren Breithaupt, Catherine Byrne, Scott Engel
Negative urgency (NU), the tendency to act impulsively when distressed, is associated with binge eating. Women who believe that eating alleviates negative affect are also more likely to binge eat. Thus, it is hypothesized that the individuals with high levels of NU, and who endorse these eating expectancies, will binge eat the following acute distress. This study tested these hypotheses using ecological momentary assessment. Sixteen women with the symptoms of BN completed clinical assessments, and were asked to report on distress and binges multiple times daily for two weeks...
January 2018: Eating Disorders
https://www.readbyqxmd.com/read/29379903/cad-cam-based-chairside-restorative-technique-with-composite-resin-for-full-mouth-adhesive-rehabilitation-of-excessively-worn-dentition
#14
Filippo Del Curto, Carlo Massimo Saratti, Ivo Krejci
Since the first introduction of the Cerec system (Sirona) in the early 1980s, the use of computer-aided design/computer-aided manufacture (CAD/CAM) technology has spread widely in modern adhesive dentistry. Thanks to this innovative technology, it has been possible to carry out chairside restorations fully managed by the clinician, with the advantages of lower costs for the patient, more rapid execution of the restorations, and the exclusion of the provisional phase. With further improvements in chairside technologies and materials, specifically in the field of composite resin blocks, it is now possible to fabricate multiple ultrathin, minimally invasive or even noninvasive restorations in one single appointment...
2018: International Journal of Esthetic Dentistry
https://www.readbyqxmd.com/read/29379324/bulimia-nervosa-in-adolescents-prevalence-and-treatment-challenges
#15
REVIEW
Lisa Hail, Daniel Le Grange
Bulimia nervosa (BN) is a serious psychiatric illness that typically develops during adolescence or young adulthood, rendering adolescents a target for early intervention. Despite the increasing research devoted to the treatment of youth with anorexia nervosa (AN) and adults with BN, there remains a dearth of evidence for treating younger individuals with BN. To date, there have been four published randomized controlled trials comparing psychosocial treatments, leaving significant room to improve treatment outcomes...
2018: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/29366932/a-systematic-review-of-attentional-biases-in-disorders-involving-binge-eating
#16
REVIEW
Monika Stojek, Lisa M Shank, Anna Vannucci, Diana M Bongiorno, Eric E Nelson, Andrew J Waters, Scott G Engel, Kerri N Boutelle, Daniel S Pine, Jack A Yanovski, Marian Tanofsky-Kraff
OBJECTIVE: Attentional bias (AB) may be one mechanism contributing to the development and/or maintenance of disordered eating. AB has traditionally been measured using reaction time in response to a stimulus. Novel methods for AB measurement include eye tracking to measure visual fixation on a stimulus, and electroencephalography to measure brain activation in response to a stimulus. This systematic review summarizes, critiques, and integrates data on AB gathered using the above-mentioned methods in those with binge eating behaviors, including binge eating, loss of control eating, and bulimia nervosa...
January 20, 2018: Appetite
https://www.readbyqxmd.com/read/29347888/patient-baseline-interpersonal-problems-as-moderators-of-outcome-in-two-psychotherapies-for-bulimia-nervosa
#17
Juan Martin Gomez Penedo, Michael J Constantino, Alice E Coyne, Samantha L Bernecker, Lotte Smith-Hansen
OBJECTIVE: We tested an aptitude by treatment interaction; namely, whether patients' baseline interpersonal problems moderated the comparative efficacy of cognitive-behavioral therapy (CBT) vs. interpersonal psychotherapy (IPT) for bulimia nervosa (BN). METHOD: Data derived from a randomized-controlled trial. Patients reported on their interpersonal problems at baseline; purge frequency at baseline, midtreatment, and posttreatment; and global eating disorder severity at baseline and posttreatment...
January 19, 2018: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/29341400/are-trans-diagnostic-models-of-eating-disorders-fit-for-purpose-a-consideration-of-the-evidence-for-food-addiction
#18
REVIEW
Janet Treasure, Monica Leslie, Rayane Chami, Fernando Fernández-Aranda
Explanatory models for eating disorders have changed over time to account for changing clinical presentations. The transdiagnostic model evolved from the maintenance model, which provided the framework for cognitive behavioural therapy for bulimia nervosa. However, for many individuals (especially those at the extreme ends of the weight spectrum), this account does not fully fit. New evidence generated from research framed within the food addiction hypothesis is synthesized here into a model that can explain recurrent binge eating behaviour...
January 17, 2018: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/29336774/altered-cortical-thickness-and-attentional-deficits-in-adolescent-girls-and-women-with-bulimia-nervosa
#19
Laura A Berner, Mihaela Stefan, Seonjoo Lee, Zhishun Wang, Kate Terranova, Evelyn Attia, Rachel Marsh
BACKGROUND: Frontostriatal and frontoparietal abnormalities likely contribute to deficits in control and attentional processes in individuals with bulimia nervosa and to the persistence of dysregulated eating across development. This study assessed these processes and cortical thickness in a large sample of adolescent girls and women with bulimia nervosa compared with healthy controls. METHODS: We collected anatomical MRI data from adolescent girls and women (ages 12-38 yr) with full or subthreshold bulimia nervosa and age-matched healthy controls who also completed the Conners Continuous Performance Test-II (CPT-II)...
January 12, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29331083/variation-in-reproductive-outcomes-of-women-with-histories-of-bulimia-nervosa-anorexia-nervosa-or-eating-disorder-not-otherwise-specified-relative-to-the-general-population-and-closest-aged-sisters
#20
Jennifer Tabler, Rebecca L Utz, Ken R Smith, Heidi A Hanson, Claudia Geist
OBJECTIVE: This study seeks to examine the long-term reproductive consequences of eating disorders (ED), to assess variation in reproductive outcomes by ED type, and to examine reproductive differences between women with previous ED diagnosis and their discordant sisters. METHOD: Using a sample of women with previous ED diagnosis generated by the Utah Population Database, this study compares the fecundity (parity) and age at first birth of women by ED subtype (bulimia nervosa [BN], anorexia nervosa [AN], and ED not otherwise specified [EDNOS]) (n = 1,579)...
January 13, 2018: International Journal of Eating Disorders
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