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Carcinoid tumor

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https://www.readbyqxmd.com/read/28323742/spontaneous-regression-of-bronchial-carcinoid-is-linked-to-a-brisk-tumor-lymphocytic-infiltrate
#1
Luca Roncati, Antonio Manenti, Francesco Piscioli, Teresa Pusiol, Giuseppe Barbolini
No abstract text is available yet for this article.
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28323740/combined-typical-carcinoid-adenocarcinoma-lung-tumor
#2
Maryam Nilforoshan, Ismael A Matus
No abstract text is available yet for this article.
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28298733/pitfalls-and-artifacts-in-the-interpretation-of-oncologic-pet-ct-of-the-chest
#3
Gustavo de Souza Portes Meirelles, Julia Capobianco, Marco Antônio Condé de Oliveira
PET/CT is widely used for the evaluation of patients with thoracic malignancies. Although the levels of (18)F-fluorodeoxyglucose (FDG) uptake are usually high in neoplastic diseases, they can also be physiological, due to artifacts. In addition, FDG uptake can occur in benign conditions such as infectious, inflammatory, and iatrogenic lesions. Furthermore, some malignant tumors, such as adenocarcinoma in situ (formerly known as bronchoalveolar carcinoma) and carcinoid tumors, may not show FDG uptake. Here, we illustrate the main pitfalls and artifacts in the interpretation of the results of oncologic PET/CT of the chest, outlining strategies for avoiding misinterpretation...
January 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28295914/development-of-a-gastric-carcinoid-tumor-following-allogeneic-hematopoietic-stem-cell-transplantation-for-early-t-cell-precursor-acute-lymphoblastic-leukemia
#4
Tsung-Yen Chang, Jin-Yao Lai, Chao-Jan Wang, Shih-Yen Chen, Tang-Her Jaing, Chuen Hsueh, Lee-Yung Shih, Shih-Hsiang Chen
Gastric carcinoid tumor is rarely diagnosed in children. We report a case of gastric carcinoid tumor that occurred after allogeneic HSCT. A 13-year-old girl with ETP acute lymphoblastic leukemia underwent allogeneic HSCT from a 7/8 HLA-matched unrelated donor. She presented with rashes, abdominal pain, and diarrhea, which were suggestive of GVHD, 7 months after HSCT. Immunosuppressive agents failed to resolve these symptoms well. After a series of evaluations, carcinoid syndrome caused by a gastric carcinoid tumor was diagnosed...
March 11, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28287937/multimodality-imaging-findings-in-carcinoid-tumors-a-head-to-toe-spectrum
#5
Ameya Jagdish Baxi, Kedar Chintapalli, Amol Katkar, Carlos S Restrepo, Sonia L Betancourt, Abhijit Sunnapwar
Carcinoid tumors are a rare biologically heterogeneous group of neuroendocrine tumors with a spectrum ranging from benign indolent to aggressive metastatic tumors. They belong to the category of amine precursor uptake and decarboxylase tumors, or apudomas. The most common sites for primary locations are the gastrointestinal and respiratory tracts; however, any organ can be involved. The clinical presentation depends on location, aggressiveness, production of biologically active amines and peptides, paraneoplastic syndromes, and tendency for metastasis...
March 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28286921/treatment-strategies-for-metastatic-neuroendocrine-tumors-of-the-gastrointestinal-tract
#6
REVIEW
Mauro Cives, Jonathan Strosberg
The therapeutic landscape of gastroenteropancreatic-neuroendocrine tumors (GEP-NETs) has evolved significantly in recent years. Current and emerging treatment options include somatostatin analogs, radiolabeled somatostatin analogs, the mTOR inhibitor everolimus, and the tyrosine kinase inhibitor sunitinib. Although high-quality data from phase III trials are lacking, cytotoxic agents are commonly used for the treatment of poorly differentiated neuroendocrine carcinomas and well-differentiated NETs originating in the pancreas...
March 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28283864/lower-gastrointestinal-neuroendocrine-neoplasms-associated-with-hereditary-cancer-syndromes-a-case-series
#7
Trilokesh D Kidambi, Christina Pedley, Amie Blanco, Emily K Bergsland, Jonathan P Terdiman
Lower gastrointestinal (GI) neuroendocrine neoplasms (NENs) of the colon and rectum are uncommon and not traditionally associated with hereditary GI cancer syndromes. However, with widespread implementation of colorectal cancer screening programs, lower GI NENs are being identified with increasing frequency. We report the first case series of six patients with lower GI NENs who were diagnosed with hereditary GI cancer syndromes by germline testing. Two patients presented with poorly differentiated rectal neuroendocrine carcinoma (NECs) with colonic polyposis and were found to have Familial Adenomatous Polyposis and MYH-Associated Polyposis, respectively...
March 10, 2017: Familial Cancer
https://www.readbyqxmd.com/read/28281997/asymptomatic-metastatic-carcinoid-tumor-discovered-by-routine-screening-mammography
#8
Julia L Brothers, Mark A Mikhitarian, Lee S Fleischer
No abstract text is available yet for this article.
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28280620/potential-actionable-targets-in-appendiceal-cancer-detected-by-immunohistochemistry-fluorescent-in-situ-hybridization-and-mutational-analysis
#9
Erkut Borazanci, Sherri Z Millis, Jeffery Kimbrough, Nancy Doll, Daniel Von Hoff, Ramesh K Ramanathan
BACKGROUND: Appendiceal cancers are rare and consist of carcinoid, mucocele, pseudomyxoma peritonei (PMP), goblet cell carcinoma, lymphoma, and adenocarcinoma histologies. Current treatment involves surgical resection or debulking, but no standard exists for adjuvant chemotherapy or treatment for metastatic disease. METHODS: Samples were identified from approximately 60,000 global tumors analyzed at a referral molecular profiling CLIA-certified laboratory. A total of 588 samples with appendix primary tumor sites were identified (male/female ratio of 2:3; mean age =55)...
February 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28279296/diagnosing-and-managing-carcinoid%C3%A2-heart%C3%A2-disease-in-patients%C3%A2-with%C3%A2-neuroendocrine-tumors-an-expert-statement
#10
REVIEW
Joseph Davar, Heidi M Connolly, Martyn E Caplin, Marianne Pavel, Jerome Zacks, Sanjeev Bhattacharyya, Daniel J Cuthbertson, Rebecca Dobson, Simona Grozinsky-Glasberg, Richard P Steeds, Giles Dreyfus, Patricia A Pellikka, Christos Toumpanakis
Carcinoid heart disease is a frequent occurrence in patients with carcinoid syndrome and is responsible for substantial morbidity and mortality. The pathophysiology of carcinoid heart disease is poorly understood; however, chronic exposure to excessive circulating serotonin is considered one of the most important contributing factors. Despite recognition, international consensus guidelines specifically addressing the diagnosis and management of carcinoid heart disease are lacking. Furthermore, there is considerable variation in multiple aspects of screening and management of the disease...
March 14, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28275490/erroneous-diagnosis-of-small-cell-lung-cancer-based-on-small-biopsies-with-far-reaching-consequences-case-report-of-a-typical-carcinoid-tumor
#11
Ioannis Kyritsis, Bettina Krebs, Sandra Kampe, Dirk Theegarten, Clemens Aigner, Stefan Welter
Although neuroendocrine tumors (NETs) of the lung are frequently discussed together, carcinoids are very different from high-grade small cell lung carcinoma (SCLC). SCLC is found in heavy-smoking, older patients, whereas smoking is not strongly associated with carcinoid tumors. We present the case of a 46-year-old never smoking woman who was misdiagnosed with SCLC. The patient was not responsive to radio-chemotherapy plus prophylactic cranial irradiation (PCI); she had a typical carcinoid (TC) tumor according to the final pathology report...
February 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28267663/appendiceal-diverticulitis-a-rare-relevant-pathology-presentation-of-a-case-report-and-review-of-the-literature
#12
Maria Leonarda Altieri, Guglielmo Niccolò Piozzi, Pierluigi Salvatori, Maurizio Mirra, Gaetano Piccolo, Natale Olivari
INTRODUCTION: Appendiceal diverticulitis is a rare pathology that mimics acute appendicitis. Appendiceal diverticula are classified into congenital and acquired with difference in incidence and pathogenesis. Appendiceal diverticulitis is often overlooked because of mildness of symptomatology with increasing risk of complications, such as perforation. Appendiceal diverticula are often associated to higher risk of neoplasm especially carcinoid tumors and mucinous adenomas. PRESENTATION OF CASE: A 40-year-old caucasic male presented into Emergency Room with right lower quadrant pain associated with vomit, abdominal tenderness, fever and moderate leukocytosis (11...
February 20, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28267211/retrospective-review-of-serotonergic-medication-tolerability-in-patients-with-neuroendocrine-tumors-with-biochemically-proven-carcinoid-syndrome
#13
Diana D Shi, David P Yuppa, Trevor Dutton, Lauren K Brais, Sarah L Minden, Ilana M Braun, Matthew H Kulke, Jennifer A Chan, Fremonta L Meyer
BACKGROUND: Patients with carcinoid tumors frequently could benefit from the pharmacologic treatment of depression and anxiety. However, many prescribers avoid serotonergic medications due to the theoretical risk of exacerbating carcinoid syndrome. METHODS: The authors conducted a retrospective chart review of patients with carcinoid tumors and elevated serotonin levels (as measured by 24-hour urine 5-hydroxyindoleacetic acid [5-HIAA]) at Dana-Farber/Brigham and Women's Cancer Center who initiated treatment with serotonergic antidepressants after a carcinoid diagnosis from 2003 to 2016...
March 7, 2017: Cancer
https://www.readbyqxmd.com/read/28256142/liver-metastasis-secondary-to-primary-mesenteric-carcinoid
#14
José Francisco Juanmartiñena Fernández, Ignacio Fernández Urién, Irene Amat Villegas, Carlos Prieto Martínez
Carcinoid tumors are rare, slow-growing neoplasms that display neuroendocrine properties. The term carcinoid is generally applied to well-differentiated neoplasms, while neuroendocrine carcinoma is reserved only for poorly differentiated lesions. They can be found throughout the different regions of the gastrointestinal system, although they have predilection for the ileum.
March 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28250899/endoscopic-submucosal-dissection-for-small-submucosal-tumors-of-the-rectum-compared-with-endoscopic-submucosal-resection-with-a-ligation-device
#15
Hideaki Harada, Satoshi Suehiro, Daisuke Murakami, Ryotaro Nakahara, Takanori Shimizu, Yasushi Katsuyama, Yasunaga Miyama, Kenji Hayasaka, Shigetaka Tounou
AIM: To evaluate the efficacy and safety of endoscopic submucosal dissection (ESD) for small rectal submucosal tumors (SMTs). METHODS: Between August 2008 and March 2016, 39 patients were treated with endoscopic submucosal resection with a ligation device (ESMR-L) (n = 21) or ESD (n = 18) for small rectal SMTs in this study. Twenty-five lesions were confirmed by histological evaluation of endoscopic biopsy prior to the procedure, and 14 lesions were not evaluated by endoscopic biopsy...
February 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28247231/update-from-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumours-what-is-new-in-the-2017-who-blue-book-for-tumours-of-the-hypopharynx-larynx-trachea-and-parapharyngeal-space
#16
Nina Gale, Mario Poljak, Nina Zidar
Chapter 3 "Tumours of the hypopharynx, larynx, trachea, and parapharyngeal space" of the World Health Organization (WHO) Blue Book 2017 "Classification of Head and Neck Tumours" shows a shortened list of entities, especially due to reducing the number of benign and malignant soft tissue tumours, malignant melanoma and some others, which are transferred to more frequently affected regions of the head and neck. The basic concept of the new edition is to assimilate all advances concerning the discussed tumours in a shorter framework, appropriate for daily work...
March 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28242984/dual-tracer-pet-imaging-68ga-dotatate-and-18f-fdg-features-in-pulmonary-carcinoid-correlation-with-tumor-proliferation-index
#17
Dhiraj Bhatkar, Ketaki Utpat, Sandip Basu, Jyotsna M Joshi
Pulmonary carcinoid tumors are rare group of lung neoplasms representing 1% of all the lung tumors. The typical bronchial carcinoids showed higher and more selective uptake of (68)Ga-DOTATATE than of (18)F-FDG on PET-CT. The Ki-67(MIB-1), a tumor proliferation index is a prognostic marker in neuroendocrine tumors for estimating tumor progression. Atypical carcinoids have higher Ki-67 index and have an increased propensity to metastasize as compared to typical ones. (68)Ga-DOTATATE PET imaging along with Ki-67 can be correlated for better management of patients with neuroendocrine tumors...
January 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28238598/carcinoid-syndrome-in-neuroendocrine-tumors-a-prognostic-effect
#18
Michel Ducreux
No abstract text is available yet for this article.
February 23, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28228194/asymptomatic-metastatic-carcinoid-tumor-discovered-by-routine-screening-mammography
#19
Julia L Brothers, Mark A Mikhitarian, Lee S Fleischer
No abstract text is available yet for this article.
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28218630/jejunal-carcinoid-tumors-presenting-as-small-bowel-obstruction
#20
David Ballard, Ryan Fransman, Guillermo Sangster, Matthew Ayo, Navdeep Samra
Carcinoid tumors are the most common form of gut neuroendocrine tumors, however, they rarely present with small bowel obstruction. We present a case of a 65-year-old woman without prior abdominal operations who presented with symptoms of small bowel obstruction. Computed tomography (CT) showed multiple air fluid levels and a transition point in the left mesentery with two soft tissue densities at the same level. The patient was taken to the operating room for surgical exploration, which showed two intramural masses in the mid and distal jejunum, which surgical pathology showed to be stage IIIB carcinoid tumor...
January 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
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