keyword
MENU ▼
Read by QxMD icon Read
search

Anorexia nervosa

keyword
https://www.readbyqxmd.com/read/28630708/what-happens-after-treatment-a-systematic-review-of-relapse-remission-and-recovery-in-anorexia-nervosa
#1
REVIEW
Sahib S Khalsa, Larissa C Portnoff, Danyale McCurdy-McKinnon, Jamie D Feusner
BACKGROUND: Relapse after treatment for anorexia nervosa (AN) is a significant clinical problem. Given the level of chronicity, morbidity, and mortality experienced by this population, it is imperative to understand the driving forces behind apparently high relapse rates. However, there is a lack of consensus in the field on an operational definition of relapse, which hinders precise and reliable estimates of the severity of this issue. The primary goal of this paper was to review prior studies of AN addressing definitions of relapse, as well as relapse rates...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28630421/a-genome-wide-association-study-of-anorexia-nervosa-suggests-a-risk-locus-implicated-in-dysregulated-leptin-signaling
#2
Dong Li, Xiao Chang, John J Connolly, Lifeng Tian, Yichuan Liu, Elizabeth J Bhoj, Nora Robinson, Debra Abrams, Yun R Li, Jonathan P Bradfield, Cecilia E Kim, Jin Li, Fengxiang Wang, James Snyder, Maria Lemma, Cuiping Hou, Zhi Wei, Yiran Guo, Haijun Qiu, Frank D Mentch, Kelly A Thomas, Rosetta M Chiavacci, Roger Cone, Bingshan Li, Patrick A Sleiman, Hakon Hakonarson
We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using a stringently defined phenotype. Analysis of phenotypic variability led to the identification of a specific genetic risk factor that approached genome-wide significance (rs929626 in EBF1 (Early B-Cell Factor 1); P = 2.04 × 10(-7); OR = 0.7; 95% confidence interval (CI) = 0.61-0.8) with independent replication (P = 0.04), suggesting a variant-mediated dysregulation of leptin signaling may play a role in AN...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28623853/the-validity-of-dsm-5-severity-specifiers-for-anorexia-nervosa-bulimia-nervosa-and-binge-eating-disorder
#3
Kathryn E Smith, Jo M Ellison, Ross D Crosby, Scott G Engel, James E Mitchell, Scott J Crow, Carol B Peterson, Daniel Le Grange, Stephen A Wonderlich
OBJECTIVE: The DSM-5 includes severity specifiers (i.e., mild, moderate, severe, extreme) for anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED), which are determined by weight status (AN) and frequencies of binge-eating episodes (BED) or inappropriate compensatory behaviors (BN). Given limited data regarding the validity of eating disorder (ED) severity specifiers, this study examined the concurrent and predictive validity of severity specifiers in AN, BN, and BED...
June 17, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28618917/reduced-cardiovascular-activation-following-chronic-stress-in-caregivers-of-people-with-anorexia-nervosa
#4
Ángel Romero-Martínez, Luis Moya-Albiol
Caring for offspring diagnosed with eating disorders (EDs) puts caregivers under high levels of chronic stress, which have negative consequences for their health. Unfortunately, caregivers have received little attention from mental health professionals. Chronic stress experienced by informal caregivers has been associated with the alteration of body homeostasis, and therefore, the functioning of various physiological systems. This could be the basis of health problems in informal caregivers of people with EDs...
June 15, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28615982/family-based-treatment-of-eating-disorders-in-adolescents-current-insights
#5
REVIEW
Renee D Rienecke
Eating disorders are serious illnesses associated with significant morbidity and mortality. Family-based treatment (FBT) has emerged as an effective intervention for adolescents with anorexia nervosa, and preliminary evidence suggests that it may be efficacious in the treatment of adolescents with bulimia nervosa. Multifamily therapy for anorexia nervosa provides a more intensive experience for families needing additional support. This review outlines the three phases of treatment, key tenets of family-based treatment, and empirical support for FBT...
2017: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/28606779/2-arachidonoylglycerol-as-a-possible-treatment-for-anorexia-nervosa-in-animal-model-in-mice
#6
Y Avraham, I Paturski, I Magen, L Vorobiev, E M Berry
We have investigated the effects of 0.001mg/kg 2-arachidonoylglycerol (2-AG) administered in combination with compounds present in the body alongside 2-AG like 2-palmitoylglycerol and 2-linoleylglycerol (also termed "entourage"), on cognitive function,food intake, and neurotransmitter levels in the hippocampus and hypothalamus of mice under diet restriction. Young female Sabra mice were treated with vehicle, 2-AG, 2-AG + entourage, 2-AG + entourage + 5-(4-Chlorophenyl)-1-(2,4-dichloro-phenyl)- 4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide (SR141716A, a CB1 antagonist) and SR141716A...
June 9, 2017: Brain Research
https://www.readbyqxmd.com/read/28604943/adipokine-profile-in-patients-with-anorexia-nervosa
#7
Agnieszka Baranowska-Bik, Bogusława Baranowska, Lidia Martyńska, Anna Litwiniuk, Małgorzata Kalisz, Jan Kochanowski, Wojciech Bik
INTRODUCTION: Anorexia nervosa (AN) is an eating disorder characterised with extremely low weight. Adipokines are adipose tissue-derived substances that show a wide spectrum of biological activities. We aimed to assess selected adipokine levels in women with AN before and after nutritional intervention. We also sought to examine whether BMI is the only confounding factor influencing adipokine assessment in AN. MATERIAL AND METHODS: Sixty-five women participated in the study: 20 individuals with AN before any treatment, 18 AN patients after nutritional intervention lasting for at least six months, and 27 women as controls...
June 12, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/28601992/prevalence-of-idiopathic-scoliosis-in-anorexia-nervosa-patients-results-from-a-cross-sectional-study
#8
Fabio Zaina, Francesca Pesenti, Luca Persani, Paolo Capodaglio, Stefano Negrini, Nicoletta Polli
PURPOSE: A long debate exists about the connection between anorexia nervosa (AN) and scoliosis due to conflicting evidence. No study so far has evaluated the prevalence of scoliosis in patients with AN. The aim of the study is to evaluate the prevalence of idiopathic scoliosis in patients with AN. METHODS: Design: cross-sectional study. STUDY GROUP: convenience sample of all patients matching the inclusion criteria. CONTROL GROUP: female participants coming from an epidemiological screening for scoliosis...
June 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28593722/macronutrient-intake-associated-with-weight-gain-in-adolescent-girls-with-anorexia-nervosa
#9
Charumathi Baskaran, Traci L Carson, Karen J Campoverde Reyes, Kendra R Becker, Meghan J Slattery, Shreya Tulsiani, Kamryn T Eddy, Ellen J Anderson, Jane L Hubbard, Madhusmita Misra, Anne Klibanski
OBJECTIVE: Adolescents and women with anorexia nervosa (AN) are known to severely restrict total calorie and fat intake. However, data are limited regarding specific macronutrient intake associated with weight gain in AN. OBJECTIVE: To prospectively investigate dietary macronutrient composition associated with weight gain in adolescent girls with AN. METHOD: A prospective naturalistic study of 90 girls 12-18 years old; 45 with AN and 45 healthy normal-weight-controls over a 6-12-month period...
June 7, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28593655/vitamin-d-levels-strongly-influence-bone-mineral-density-and-bone-turnover-markers-during-weight-gain-in-female-patients-with-anorexia-nervosa
#10
Alessandro Giollo, Luca Idolazzi, Cristian Caimmi, Angelo Fassio, Francesco Bertoldo, Riccardo Dalle Grave, Marwan El Ghoch, Simona Calugi, Paola Vittoria Bazzani, Ombretta Viapiana, Maurizio Rossini, Davide Gatti
OBJECTIVE: The aim of the study was to investigate a potential role for vitamin D status on bone mineral density (BMD) during weight gain in patients with anorexia nervosa (AN). METHOD: Spine and hip BMD assessed by dual-energy X-ray absorptiometry (DXA), serum vitamin D (25-OH-D), N-propeptide of type I collagen (P1NP), C-terminal telopeptide of type I collagen (CTX), and intact parathyroid hormone (PTH) were measured before and after a 20-week intensive weight-restoration program in ninety-one female patients with AN and secondary amenorrhoea...
June 7, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28593630/investigating-the-dsm-5-severity-specifiers-based-on-thinness-for-adults-with-anorexia-nervosa
#11
Deborah Lynn Reas, Øyvind Rø
OBJECTIVE: The DSM-5 severity classification scheme for adults with anorexia nervosa (AN) is based upon current body mass index (BMI; kg/m(2) ). This study examined the utility of the DSM-5 severity specifiers for adults with AN in relation to core cognitive and behavioral features of eating pathology and associated psychosocial impairment. METHODS: A clinical sample of 146 adult AN patients (140 women, 6 men) were categorized using DSM-5 current BMI severity specifiers and assessed with the Eating Disorder Examination-Questionnaire (EDE-Q) and Clinical Impairment Assessment (CIA)...
June 7, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28589469/examining-a-momentary-mediation-model-of-appearance-related-stress-anxiety-and-eating-disorder-behaviors-in-adult-anorexia-nervosa
#12
Tyler B Mason, Jason M Lavender, Stephen A Wonderlich, Ross D Crosby, Scott G Engel, James E Mitchell, Scott J Crow, Daniel Le Grange, Carol B Peterson
PURPOSE: Appearance-related stress may result from appearance-focused events such as seeing one's reflection, seeing media images, and shopping for clothes. The purpose of this study was to examine the prospective association between momentary appearance-related stress and eating disorder (ED) behaviors (i.e., binge eating and vomiting) among women with anorexia nervosa (AN) using ecological momentary assessment (EMA). We hypothesized that appearance-related stress at Time 1 would predict binge eating and vomiting at Time 2, and that this prospective association would be mediated by momentary anxiety at Time 2 (controlling for anxiety at Time 1)...
June 6, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28587552/anorexia-nervosa-and-bulimia-nervosa-a-psychotherapeutic-cognitive-constructivist-approach
#13
Cristiano Nabuco de Abreu, Raphael Cangelli Filho
Of the eating disorders, anorexia nervosa and bulimia nervosa are the ones that have made adolescent patients-often females and aged younger and younger-seek for help. This help is provided through a multidisciplinary treatment involving psychiatrists, psychologists and dietists. Psychotherapy has shown to be an efficient component for these patients' improvement. The present article aims at presenting a proposal of psychotherapeutic treatment based on a cognitive-constructivist approach.
June 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28586943/oxytocin-and-its-relationship-to-body-composition-bone-mineral-density-and-hip-geometry-across-the-weight-spectrum
#14
Melanie Schorr, Dean A. Marengi, Reitumetse Pulumo, Elaine Yu, Kamryn T. Eddy, Anne Klibanski, Karen K. Miller, Elizabeth A. Lawson
Context: Oxytocin (OXT), an anorexigenic hypothalamic hormone anabolic to bone, may reflect energy availability. Basal serum OXT levels are lower in anorexia nervosa (AN, state of energy deficit) than healthy controls (HC) and negatively associated with spine bone density (BMD). However, reports are conflicting regarding OXT levels in overweight/obesity (OB, state of energy excess). Furthermore, relationships between OXT and BMD in OB and hip geometry across the weight spectrum are unknown...
May 10, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28586130/daily-changes-in-composition-and-diversity-of-the-intestinal-microbiota-in-patients-with-anorexia-nervosa-a-series-of-three-cases
#15
Susan C Kleiman, Elaine M Glenny, Emily C Bulik-Sullivan, Eun Young Huh, Matthew C B Tsilimigras, Anthony A Fodor, Cynthia M Bulik, Ian M Carroll
Anorexia nervosa, a severe psychiatric illness, is associated with an intestinal microbial dysbiosis. Individual microbial signatures dominate in healthy samples, even over time and under controlled conditions, but whether microbial markers of the disorder overcome inter-individual variation during the acute stage of illness or renourishment is unknown. We characterized daily changes in the intestinal microbiota in three acutely ill patients with anorexia nervosa over the entire course of hospital-based renourishment and found significant, patient-specific changes in microbial composition and diversity...
June 6, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28584660/mental-capacity-to-consent-to-treatment-and-the-association-with-outcome-a-longitudinal-study-in-patients-with-anorexia-nervosa
#16
Isis F F M Elzakkers, Unna N Danner, Lot C Sternheim, Daniel McNeish, Hans W Hoek, Annemarie A van Elburg
BACKGROUND: Relevance of diminished mental capacity in anorexia nervosa (AN) to course of disorder is unknown. AIMS: To examine prognostic relevance of diminished mental capacity in AN. METHOD: A longitudinal study was conducted in 70 adult female patients with severe AN. At baseline, mental capacity was assessed by psychiatrists, and clinical and neuropsychological data (decision-making) were collected. After 1 and 2 years, clinical and neuropsychological assessments were repeated, and remission and admission rates were calculated...
May 2017: BJPsych Open
https://www.readbyqxmd.com/read/28584286/genome-wide-meta-analysis-of-cognitive-empathy-heritability-and-correlates-with-sex-neuropsychiatric-conditions-and-cognition
#17
V Warrier, K L Grasby, F Uzefovsky, R Toro, P Smith, B Chakrabarti, J Khadake, E Mawbey-Adamson, N Litterman, J-J Hottenga, G Lubke, D I Boomsma, N G Martin, P K Hatemi, S E Medland, D A Hinds, T Bourgeron, S Baron-Cohen
We conducted a genome-wide meta-analysis of cognitive empathy using the 'Reading the Mind in the Eyes' Test (Eyes Test) in 88,056 research volunteers of European Ancestry (44,574 females and 43,482 males) from 23andMe Inc., and an additional 1497 research volunteers of European Ancestry (891 females and 606 males) from the Brisbane Longitudinal Twin Study. We confirmed a female advantage on the Eyes Test (Cohen's d=0.21, P<2.2 × 10(-16)), and identified a locus in 3p26.1 that is associated with scores on the Eyes Test in females (rs7641347, Pmeta=1...
June 6, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28581536/schizophrenia-and-anorexia-nervosa-reciprocal-relationships-a-literature-review
#18
REVIEW
Justyna Morylowska-Topolska, Rafał Ziemiński, Agnieszka Molas, Jacek Gajewski, Marta Flis, Ewa Stelmach, Hanna Karakuła-Juchnowicz
Although schizophrenia and anorexia nervosa are seemingly very distinct psychiatric disorders, their symptoms are connected by various types of relationships. The present article reviews the literature and recapitulates the views of various authors on the links between these two disorders. Symptoms of anorexia may 1) precede the onset of psychosis; 2) evolve in its active phase or more rarely manifest in remission; and, conversely, 3) psychotic symptoms may occur transiently in the course of anorexia nervosa...
April 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/28581534/bone-mineralization-and-densitometric-evaluation-of-vertebral-fractures-in-women-6-21-years-after-the-onset-of-anorexia-nervosa-symptoms
#19
Gabriela Jagielska, Jerzy Przedlacki, Zbigniew Bartoszewicz, Agnieszka Kondracka, Agnieszka Butwicka, Ewa Racicka, Olgierd Rowiński, Rafał Brzewski, Tomasz Wolańczyk, Celina Tomaszewicz-Libudzic, Urszula Szymańska
OBJECTIVES: We attempted to assess bone mineralization and the frequency of fractures occurrence in women with a history of treatment of anorexia nervosa (AN) in adolescence. METHODS: 47 women (age 20-36.8 years) were re-examined 6.33-21,2 years after the onset of AN symptoms. Bone mineral density (BMD) of total body, lumbar spine, femoral neck, total hip (DXA) and densitometric Vertebral Fracture Assessment (VFA) were performed on 46 of women and BAP, P1NP, CTX, estradiol, testosterone, cortisol, IGF-1, leptin, DHEA-S on 45 of women entered for the current study...
April 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/28581533/gastrointestinal-complications-and-refeeding-guidelines-in-patients-with-anorexia-nervosa
#20
REVIEW
Żaneta Malczyk, Joanna Małgorzata Oświęcimska
Anorexia nervosa (AN) is the third most common disorder, after obesity and asthma, in the population of adolescents between 13-18 years of age. Food intake reduction is associated with whole body dysfunction, affecting its physical, psychological and social spheres. As a result of starvation, dysfunction develops in virtually all systems and organs. However, most frequently patients with AN complain of digestive symptoms, such as a feeling of fullness after meals, pain in the upper abdomen, dysphagia, nausea, bloating and constipation...
April 30, 2017: Psychiatria Polska
keyword
keyword
5962
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"