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Anorexia nervosa

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https://www.readbyqxmd.com/read/29451957/outcome-of-childhood-anorexia-nervosa-the-results-of-a-five-to-ten-year-follow-up-study
#1
Beate Herpertz-Dahlmann, Astrid Dempfle, Karin Maria Egberts, Viola Kappel, Kerstin Konrad, Jennifer Anne Vloet, Katharina Bühren
OBJECTIVE: Although admissions of children with anorexia nervosa (AN) are increasing, there remains a dearth of up-to-date knowledge of the course and outcome of early-onset AN. The aim of the present study was to investigate the outcomes of patients with AN onset before the age of 14. METHOD: Sixty-eight consecutive former patients who met the DSM-IV criteria for AN and who had been treated at one of three German university hospitals were asked to participate in a follow-up study...
February 16, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29445881/study-of-salivary-and-serum-vaspin-and-total-antioxidants-in-anorexia-nervosa
#2
Elzbieta Paszynska, Marta Tyszkiewicz-Nwafor, Agnieszka Slopien, Monika Dmitrzak-Weglarz, Agata Dutkiewicz, Teresa Grzelak
OBJECTIVES: Patients with anorexia nervosa (AN) are primarily at high risk of multiple somatic complications, including oral diseases. In recent years, a number of new molecules that may play a potentially important role in AN progress and prognosis have been identified in saliva, but their exact roles are still poorly understood. Two such group of substances are antioxidants and vaspin. The purpose of this observational, cross-sectional study was to measure both the salivary and serum total antioxidant status (TAS), and vaspin (VASP) concentrations of patients with AN in comparison to an average population...
February 14, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29441204/relationships-between-compulsive-exercise-quality-of-life-psychological-distress-and-motivation-to-change-in-adults-with-anorexia-nervosa
#3
Sarah Young, Stephen Touyz, Caroline Meyer, Jon Arcelus, Paul Rhodes, Sloane Madden, Kathleen Pike, Evelyn Attia, Ross D Crosby, Phillipa Hay
Background: For people with anorexia nervosa (AN), compulsive exercise is characterized by extreme concerns about the perceived negative consequences of stopping/reducing exercise, dysregulation of affect, and inflexible exercise routines. It is associated with increased eating disorder psychopathology and poor clinical outcome. However, its relationships with two important clinical issues, quality of life (QoL) and motivation to change, are currently unknown. This study aimed to assess the cross-sectional relationships between compulsive exercise, QoL, psychological distress (anxiety and depressive symptoms, and obsessive-compulsive traits) and motivation to change in patients with AN...
2018: Journal of Eating Disorders
https://www.readbyqxmd.com/read/29437028/changes-in-the-peripheral-endocannabinoid-system-as-a-risk-factor-for-the-development-of-eating-disorders
#4
Anna Capasso, Walter Milano, Omar Cauli
BACKGROUND AND OBJECTIVE: Eating Disorder (ED) is characterized by persistently and severely disturbed eating behaviours. They arise from a combination of long-standing behavioural, emotional, psychological, interpersonal, and social factors and result in insufficient nutrient ingestion and/or adsorption. The three main EDs are: anorexia nervosa, bulimia nervosa, and binge eating disorder. We review the role of peripheral endocannabinoids in eating behaviour. DISCUSSION: The neuronal pathways involved in feeding behaviours are closely related to catecholaminergic, serotoninergic and peptidergic systems...
February 12, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29437020/anorexia-nervosa-and-comorbid-psychopathology
#5
Simonetta Marucci, Laura Dalla Ragione, Giulia De Iaco, Tania Mococci, Maria Vicini, Edoardo Guastamacchia, Vincenzo Triggiani
There is great interest, supported by clinical experience, in the relationship between Eating Disorders (EDs) and psychiatric symptoms and diseases. The psychopathology of EDs is also referred to many risk and protective factors, and there is some evidence in the literature, also about genetic and neurobiological factors involved. EDs are often associated with pre-morbid psychiatric disorders, personality disorders, substance abuse, mood and anxiety disorders. The great amount of scientific articles dealing with the relationship between EDs and psychopathology confirms the complexity of these problems and the difficulties in diagnosis and treatment...
February 12, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29432507/application-of-phase-angle-for-evaluation-of-the-nutrition-status-of-patients-with-anorexia-nervosa
#6
REVIEW
Teresa Małecka-Massalska, Joanna Popiołek, Mariusz Teter, Iwona Homa-Mlak, Mariola Dec, Agata Makarewicz, Hanna Karakuła-Juchnowicz
The evaluation of the nutrition status of patients has been the subject of interest of many scientific disciplines. Any deviation from normal values is a serious clinical problem. There are multiple nutrition status evaluation methods used including diet history, scales and questionnaires, physical examination, anthropometric measurements, biochemical measurements, function tests, as well as bioelectric impedance analysis or adipometry. Phase angle, obtained by means of bioelectric impedance analysis, is another parameter that is being more and more frequently applied in nutrition status monitoring...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29432500/large-animals-as-potential-models-of-human-mental-and-behavioral-disorders
#7
REVIEW
Michał Danek, Janusz Danek, Aleksander Araszkiewicz
Many animal models in different species have been developed for mental and behavioral disorders. This review presents large animals (dog, ovine, swine, horse) as potential models of this disorders. The article was based on the researches that were published in the peer-reviewed journals. Aliterature research was carried out using the PubMed database. The above issues were discussed in the several problem groups in accordance with the WHO International Statistical Classification of Diseases and Related Health Problems 10thRevision (ICD-10), in particular regarding: organic, including symptomatic, disorders; mental disorders (Alzheimer's disease and Huntington's disease, pernicious anemia and hepatic encephalopathy, epilepsy, Parkinson's disease, Creutzfeldt-Jakob disease); behavioral disorders due to psychoactive substance use (alcoholic intoxication, abuse of morphine); schizophrenia and other schizotypal disorders (puerperal psychosis); mood (affective) disorders (depressive episode); neurotic, stress-related and somatoform disorders (posttraumatic stress disorder, obsessive-compulsive disorder); behavioral syndromes associated with physiological disturbances and physical factors (anxiety disorders, anorexia nervosa, narcolepsy); mental retardation (Cohen syndrome, Down syndrome, Hunter syndrome); behavioral and emotional disorders (attention deficit hyperactivity disorder)...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29428775/evaluation-of-the-dsm-5-severity-ratings-for-anorexia-nervosa-in-a-clinical-sample
#8
Antonios Dakanalis, C Alix Timko, Fabrizia Colmegna, Giuseppe Riva, Massimo Clerici
We examined the validity and utility of the DSM-5 severity ratings for anorexia nervosa (AN) in a clinical (treatment-seeking) sample (N = 273; 95.6% women). Participants classified with mild, moderate, severe, and extreme severity of AN based on their measured body mass index, differed significantly from each other in eating disorder features, putative maintenance factors, and illness-specific functional impairment (medium effect sizes). However, they were statistically indistinguishable in psychiatric-disorder comorbidity and distress, demographics, and age-of-AN onset...
February 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29417594/feasibility-of-a-parent-education-and-skills-workshop-for-improving-response-to-family-based-treatment-of-adolescent-anorexia-nervosa
#9
Maria Ganci, Martin Pradel, Elizabeth K Hughes
OBJECTIVE: Early response to family-based treatment (FBT) is a robust predictor of positive outcomes for adolescents with anorexia nervosa (AN). We introduced a parent education and skills workshop in the first 4 weeks of treatment with the aim of improving changes in parent self-efficacy in FBT and, in turn, patient weight gain. METHOD: Forty-five families who had at least one parent attend the workshop were compared to a matched control of families who did FBT before the workshop was introduced...
February 8, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29417593/medical-findings-in-1-026-consecutive-adult-inpatient-residential-eating-disordered-patients
#10
Philip S Mehler, Dan V Blalock, Keegan Walden, Simrat Kaur, Jennifer McBride, Kristine Walsh, Jennifer Watts
OBJECTIVE: Eating disorders are associated with multiple medical complications. We report contemporary medical data, for newly admitted adult inpatient and residential level of care patients. METHOD: Medical records of a transdiagnostic sample of 1,026 patients, with eating disorders, were retrospectively reviewed for the presence of a broad array of medical complications at time of admission. The prevalence of physiologically relevant medical complications was assessed across major eating disorder categories...
February 8, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29417446/linking-the-gut-microbiota-to-bone-health-in-anorexia-nervosa
#11
REVIEW
Nicole C Aurigemma, Kristen J Koltun, Hannah VanEvery, Connie J Rogers, Mary Jane De Souza
PURPOSE OF REVIEW: The purpose of this review is to examine the anorexia nervosa-microbiota-bone relationship, offering a compilation of the relevant human and animal studies that may contribute to a more comprehensive understanding of potential mechanisms involved. RECENT FINDINGS: Recent studies have implicated fermentation by-products of the gut microbiota in bone metabolism. Compromised bone health often accompanies anorexia nervosa due to energy deficiency and hypoestrogenism...
February 7, 2018: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/29413819/caregiver-burden-and-illness-perceptions-in-caregivers-of-medically-hospitalized-youth-with-anorexia-nervosa
#12
Abigail Matthews, Katrina R Lenz, James Peugh, Emily C Copps, Claire M Peterson
Caregiver burden is common in caregivers of youth with anorexia nervosa (AN) and could impede the successful implementation of family-based therapy (FBT). Thus, it is important to better understand mechanisms by which caregiver burden is developed and maintained. This study aimed to examine the relation between caregiver illness perceptions about AN, symptom severity indicators, and caregiver burden in a sample of medically hospitalized youth with AN. Fifty-one youth with AN (N = 34) or Atypical AN (AAN; N = 17; mean age = 14...
February 1, 2018: Eating Behaviors
https://www.readbyqxmd.com/read/29413810/transdiagnostic-vs-disorder-focused-perspective-in-children-and-adolescents-with-eating-disorders-findings-from-a-large-multisite-exploratory-study
#13
O Curzio, S Maestro, G Rossi, S Calderoni, L Giombini, S Scardigli, L Dalla Ragione, F Muratori
BACKGROUND: The transdiagnostic model of eating disorders (ED) proposes common cognitive mechanisms in patients with ED psychopathology. Little is known about their role in the maintenance of ED in children and adolescents. This study aimed to determine whether the relationships between key factors (low self-esteem, weight and shape control, clinical perfectionism, interpersonal problems, distress and mood instability) and core maintaining mechanisms (binge-eating and restraint) would support a transdiagnostic theory in young patients...
February 5, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29412456/cortical-thickness-patterns-as-state-biomarker-of-anorexia-nervosa
#14
Luca Lavagnino, Benson Mwangi, Bo Cao, Megan E Shott, Jair C Soares, Guido K W Frank
OBJECTIVE: Only few studies have investigated cortical thickness in anorexia nervosa (AN), and it is unclear whether patterns of altered cortical thickness can be identified as biomarkers for AN. METHOD: Cortical thickness was measured in 19 adult women with restricting-type AN, 24 individuals recovered from restricting-type AN (REC-AN) and 24 healthy controls. Those individuals with current or recovered from AN had previously shown altered regional cortical volumes across orbitofrontal cortex and insula...
February 7, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29411462/delayed-gastric-emptying-and-altered-antrum-protein-metabolism-during-activity-based-anorexia
#15
S Nobis, A Morin, N Achamrah, L Belmonte, R Legrand, P Chan, J-L do Rego, D Vaudry, G Gourcerol, P Déchelotte, A Goichon, M Coëffier
BACKGROUND: Anorexia nervosa, a restrictive eating disorder, is often associated with gastrointestinal disorders, particularly a delayed gastric emptying. However, the mechanisms remained poorly documented. Thus, we aimed to evaluate gastric emptying and antrum protein metabolism in the Activity-Based Anorexia model (ABA). METHODS: Females C57Bl/6 mice were randomized into 3 groups: Control, ABA, and Limited Food Access (LFA). Food access has been progressively limited from 6 h/day at day 6 to 3 h/day at day 9 and until day 17...
February 6, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29407524/metabolic-inflammatory-vascular-comorbidity-in-psychiatric-disorders-soluble-epoxide-hydrolase-seh-as-a-possible-new-target
#16
REVIEW
W Swardfager, M Hennebelle, D Yu, B D Hammock, A J Levitt, K Hashimoto, A Y Taha
The common and severe psychiatric disorders, including major depressive disorder (MDD) and bipolar disorder (BD), are associated with inflammation, oxidative stress and changes in peripheral and brain lipid metabolism. Those pathways are implicated in the premature development of vascular and metabolic comorbidities, which account for considerable morbidity and mortality, including increased dementia risk. During endoplasmic reticulum stress, the soluble epoxide hydrolase (sEH) enzyme converts anti-inflammatory fatty acid epoxides generated by cytochrome p450 enzymes into their corresponding and generally less anti-inflammatory, or even pro-inflammatory, diols, slowing the resolution of inflammation...
February 2, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29402371/-assessing-nutritional-status-of-severe-malnutrition-patients-by-bioelectrical-impedance-technique-a-multicenter-prospective-study
#17
Qiang Li, Xueni Li, Yuxin Leng, Xi Zhu, Gaiqi Yao
OBJECTIVE: To assess the nutritional status of severe malnutrition patients with anorexia nervosa by multi-frequency bioelectrical impedance technique, and to provide the basis for nutritional support therapy. METHODS: A prospective study was conducted. Twenty-six severe malnutrition patients with anorexia nervosa, body mass index (BMI) ≤ 16 kg/m2 admitted to intensive care unit (ICU) of Peking University Third Hospital and general three ward of Peking University Sixth Hospital from June 1st to September 30th, 2017 were enrolled...
February 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29397562/intimate-stimuli-result-in-fronto-parietal-activation-changes-in-anorexia-nervosa
#18
L van Zutphen, S Maier, N Siep, G A Jacob, O Tüscher, L Tebartz van Elst, A Zeeck, A Arntz, M-F O'Connor, H Stamm, M Hudek, Andreas Joos
BACKGROUND: Intimacy is a key psychological problem in anorexia nervosa (AN). Empirical evidence, including neurobiological underpinnings, is however, scarce. OBJECTIVE: In this study, we evaluated various emotional stimuli including intimate stimuli experienced in patients with AN and non-patients, as well as their cerebral response. METHODS: Functional magnetic resonance imaging was conducted using stimuli with positive, neutral, negative and intimate content...
February 3, 2018: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29394945/computer-aided-sentiment-analysis-of-anorexia-nervosa-patients-vocabulary
#19
Dominik Spinczyk, Karolina Nabrdalik, Katarzyna Rojewska
BACKGROUND: Diagnosing and treating anorexia nervosa is an important challenge for modern psychiatry. Taking into account a connection between the mental state of a person and the characteristics of their language, this paper presents developed and tested method for analyzing the written statements of patients with anorexia nervosa and healthy individuals, including the identification of keywords. METHODS: Due to the short nature of the texts, which is related to the difficulty of expressing oneself about one's body when suffering from anorexia, the bag of words approach was used for documents' information representation...
February 2, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29389338/dietary-assessment-and-counseling-for-dental-erosion
#20
Teresa A Marshall
BACKGROUND AND OVERVIEW: Dental erosion occurs after exposure to intrinsic or extrinsic acids. Exposure to intrinsic gastrointestinal acids is associated with anorexia nervosa, bulimia nervosa, rumination syndrome, or gastroesophageal reflux. Extrinsic dietary acids from foods or beverages also can cause erosion, particularly when exposure is prolonged by holding or swishing behaviors. CONCLUSIONS: Clinicians should screen patients exhibiting dental erosion for anorexia nervosa, bulimia nervosa, rumination syndrome, and gastroesophageal reflux disease...
February 2018: Journal of the American Dental Association
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