keyword
https://read.qxmd.com/read/38414442/two-chinese-patients-of-auriculocondylar-syndrome-2-a-novel-plcb4-splicing-variant-and-5-year-follow-up
#21
JOURNAL ARTICLE
Yunting Lin, Ye Zhang, Jian Ma, Shu Liu, Yongxi Liu, Chaoxiang Yang, Chunhua Zeng, Xianqiong Luo
OBJECTIVE: Auriculocondylar syndrome (ARCND) is a set of rare craniofacial malformations characterized by variable micrognathia, ear malformations, and mandibular condyle hypoplasia, and other accompanying features with phenotypic complexity. ARCND2 caused by pathogenic variants in the PLCB4 gene is a very rare disease with less than 50 patients reported and only 36 different variants of the PLCB4 gene recorded in HGMD. This study aims to enrich the patient resources, clinical data and mutational spectrum of ARCND2...
February 28, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38405031/the-prevalence-of-bilateral-hearing-loss-in-the-united-states-in-2019-a-small-area-estimation-modelling-approach-for-obtaining-national-state-and-county-level-estimates-by-demographic-subgroup
#22
JOURNAL ARTICLE
David B Rein, Carolina Franco, Nicholas S Reed, Evan R Herring-Nathan, Phoebe A Lamuda, Katelin M Alfaro Hudak, Wen Hu, Alex J Hartzman, Karl R White, John S Wittenborn
BACKGROUND: The goal of this study was to re-estimate rates of bilateral hearing loss Nationally, and create new estimates of hearing loss prevalence at the U.S. State and County levels. METHODS: We developed small area estimation models of mild, and moderate or worse bilateral hearing loss in the U.S. using data from the National Health and Nutrition Examination Survey (2001-2012, 2015-2018), the American Community Survey (2019), Census County Business Patterns (2019); Social Security Administration Data (2019); Medicare Fee-for-Service and Advantage claims data (2019); the Area Health Resources File (2019), and other sources...
February 2024: Lancet Reg Health Am
https://read.qxmd.com/read/38369737/knot-and-ear-sign-a-pathognomonic-ultrasonographic-feature-of-suture-granuloma-after-thyroid-surgery
#23
JOURNAL ARTICLE
Pae Sun Suh, So Yeong Jeong, Jung Hwan Baek, Tae Yong Kim, Yu-Mi Lee, Dong Eun Song, Yun Seo Park, Je Young Ahn, Sae Rom Chung, Young Jun Choi, Jeong Hyun Lee
PURPOSE: This study investigated the clinical and ultrasonographic (US) findings of suture granulomas and recurrent tumors, and aimed to identify specific characteristics of suture granulomas through an experimental study. METHODS: This retrospective study included 20 pathologically confirmed suture granulomas and 40 recurrent tumors between January 2010 and December 2020. The clinical findings included suture material, surgery, and initial TNM stage. The US findings included shape, size, margin, echogenicity, heterogeneity, vascularity, and internal echogenic foci...
March 2024: Ultrasonography
https://read.qxmd.com/read/38358798/innovative-approaches-to-menstruation-and-fertility-tracking-using-wearable-reproductive-health-technology-systematic-review
#24
REVIEW
Lynnette Lyzwinski, Mohamed Elgendi, Carlo Menon
BACKGROUND: Emerging digital health technology has moved into the reproductive health market for female individuals. In the past, mobile health apps have been used to monitor the menstrual cycle using manual entry. New technological trends involve the use of wearable devices to track fertility by assessing physiological changes such as temperature, heart rate, and respiratory rate. OBJECTIVE: The primary aims of this study are to review the types of wearables that have been developed and evaluated for menstrual cycle tracking and to examine whether they may detect changes in the menstrual cycle in female individuals...
February 15, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38326173/use-of-auditory-feedback-amplifier-in-women-without-voice-complaints-a-comparison-of-acoustic-measures-self-rated-vocal-effort-and-voice-intensity
#25
JOURNAL ARTICLE
Moisés do Carmo Alves, Patrícia Cotta Mancini, Letícia Caldas Teixeira
OBJECTIVE: To compare the immediate effects of using MindVox in women without voice complaints for 1, 3, 5, and 7 minutes of reading tasks, on acoustic measurements of the vocal signal in low, medium, and strong intensity emissions; on self-rated effort vocal, and on the intensity of voice reception and production. METHODS: Participants read one text using MindVox for 1, 3, 5, and 7 minutes. After each time, measures of self-rated vocal effort were collected (BORG CR10-BR Scale), as well as samples of the vowel /e/ at low (>70 dB), moderate (≥70 dB and ≤80 dB), and high intensities (>80 dB)...
February 6, 2024: Journal of Voice
https://read.qxmd.com/read/38326163/advocating-for-enhanced-patient-engagement-in-breast-cancer-care-impact-of-residual-increased-lateral-adiposity-and-consideration-of-the-pursuit-of-living-flat
#26
REVIEW
Aaron J Knowles
Breast cancer is a significant health concern, accounting for a substantial proportion of cancer cases. Despite improvements in cancer survivorship, many women still require mastectomy as part of their therapeutic treatment. Mastectomy alone or delayed breast reconstruction (DBR) are two options available to women not suitable for immediate breast reconstruction at initial mastectomy. However, the presence of increased lateral adiposity (ILA) following mastectomy, commonly referred to as ``dog-ears,'' can lead to discomfort and aesthetic concerns...
January 17, 2024: Clinical Breast Cancer
https://read.qxmd.com/read/38302682/molecular-analysis-of-pseudomonas-aeruginosa-isolates-with-mutant-gyra-gene-and-development-of-a-new-ciprofloxacin-derivative-for-antimicrobial-therapy
#27
JOURNAL ARTICLE
Yasir Adil Jabbar Alabdali, Dhay Ali Azeez, Murad G Munahi, Zainab I Kuwait
This study focuses on the prevalence of Pseudomonas aeruginosa in various medical specimens. In addition, the investigates of this research shows the genetic analysis of pathogen-resistant isolates and chemical modifications to ciprofloxacin. A total of 225 specimens from men and women aged 30 to 60 were carefully collected and examined, including samples from wound, burn, urine, sputum, and ear samples. The data were obtained from AL Muthanna hospitals. PCR-RFLP and gene expression analysis were used to identify resistant strains and explore the genetic basis of antibiotic resistance...
February 1, 2024: Molecular Biotechnology
https://read.qxmd.com/read/38287481/probabilities-of-isolated-and-co-occurring-vestibular-disorder-symptom-clusters-identified-using-the-dizziness-symptom-profile
#28
JOURNAL ARTICLE
Claire E Murphy, Richard A Roberts, Erin M Picou, Gary P Jacobson, Andrea P Green
OBJECTIVES: Dizziness is among the most common reasons people seek medical care. There are data indicating patients with dizziness, unsteadiness, or vertigo may have multiple underlying vestibular disorders simultaneously contributing to the overall symptoms. Greater awareness of the probability that a patient will present with symptoms of co-occurring vestibular disorders has the potential to improve assessment and management, which could reduce healthcare costs and improve patient quality of life...
January 30, 2024: Ear and Hearing
https://read.qxmd.com/read/38282287/maternal-pre-pregnancy-overweight-or-obesity-and-risk-of-birth-defects-in-offspring-population-based-cohort-study
#29
JOURNAL ARTICLE
Weiying Liu, Luzhong Ren, Fang Fang, Ruoqing Chen
INTRODUCTION: Maternal obesity, a health condition increasingly prevalent worldwide, has been suggested to be associated with a higher risk of birth defects in offspring, whereas evidence from population-based data from China was largely lacking. Additionally, the role of gestational diabetes in the association between maternal obesity and birth defects remains unclear. We aimed to investigate the association of maternal pre-pregnancy overweight or obesity with any and different types of birth defects in offspring and the interaction between pre-pregnancy overweight or obesity and gestational diabetes...
January 28, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38251561/benralizumab-for-eosinophilic-granulomatosis-with-polyangiitis-a-retrospective-multicentre-cohort-study
#30
MULTICENTER STUDY
Alessandra Bettiol, Maria Letizia Urban, Roberto Padoan, Matthieu Groh, Giuseppe Lopalco, Allyson Egan, Vincent Cottin, Paolo Fraticelli, Claudia Crimi, Stefano Del Giacco, Laura Losappio, Laura Moi, Francesco Cinetto, Marco Caminati, Pavel Novikov, Alvise Berti, Paolo Cameli, Pascal Cathébras, Angelo Coppola, Cécile-Audrey Durel, Marco Folci, Alberto Lo Gullo, Carlo Lombardi, Sara Monti, Paola Parronchi, Carlos Martinez Rivera, Roser Solans, Angelo Vacca, Georgina Espígol-Frigolé, Gabriella Guarnieri, Fulvia Chieco Bianchi, Maria Rita Marchi, Colas Tcherakian, Jean-Emmanuel Kahn, Florenzo Iannone, Vincenzo Venerito, Charlene Desaintjean, Gianluca Moroncini, Santi Nolasco, Giulia Anna Maria Luigia Costanzo, Jan Walter Schroeder, Camillo Ribi, Michelangelo Tesi, Elena Gelain, Irene Mattioli, Federica Bello, David Jayne, Domenico Prisco, Augusto Vaglio, Giacomo Emmi
BACKGROUND: Interleukin-5 (IL-5) inhibitors represent novel therapies for eosinophilic granulomatosis with polyangiitis (EGPA). This study assessed the effectiveness and safety of the IL-5 receptor inhibitor benralizumab in a European cohort of patients with EGPA. METHODS: This retrospective cohort study included patients with EGPA from 28 European referral centres of the European EGPA Study Group across six countries (Italy, France, UK, Russia, Spain, and Switzerland) who received benralizumab as any line of treatment between Jan 1, 2019, and Sep 30, 2022...
December 2023: Lancet Rheumatology
https://read.qxmd.com/read/38231268/etiologic-distribution-of-dizziness-vertigo-in-a-neurological-outpatient-clinic-according-to-the-criteria-of-the-international-classification-of-vestibular-disorders-a-single-center-study
#31
JOURNAL ARTICLE
Yue Xing, Lihong Si, Wanting Zhang, Yuru Wang, Kangzhi Li, Xu Yang
OBJECTIVE: The study aimed to determine the etiological characteristics of patients with dizziness/vertigo attending a neurological clinic according to the criteria of the International Classification of Vestibular Disorders (ICVD), hoping to provide a valuable reference for clinicians to diagnose and treat dizziness/vertigo. METHOD: A total of 638 consecutive patients with a chief complaint of dizziness/vertigo who attended the vertigo clinic of our neurology department from January 2019 to January 2020 were included...
January 17, 2024: Journal of Neurology
https://read.qxmd.com/read/38225396/does-acute-isolated-sphenoidal-sinusitis-meet-the-criteria-of-the-recent-acute-sinusitis-guidelines-epos2020
#32
JOURNAL ARTICLE
Raed Farhat, Ashraf Khater, Nidal El Khatib, Majd Asakly, Aviva Ron, Alaa Safia, Marwan Karam, Saqr Massoud, Yaniv Avraham, Shlomo Merchavy
INTRODUCTION: Isolated sphenoidal sinusitis (ISS) is a rare disease with non-specific symptoms and a potential for complications. Diagnosis is made clinically, endoscopically, and with imaging like CT scans or MRIs. This study aimed to evaluate if ISS meets the EPOS 2020 criteria for diagnosing acute rhinosinusitis and if new diagnostic criteria are needed. MATERIALS AND METHODS: The study analyzed 193 charts and examination records from 2000 to 2022 in patients diagnosed with isolated sphenoidal sinusitis at the Ziv Medical Center in Safed, Israel...
January 16, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38219742/predictors-of-non-rhinogenic-facial-pain-or-pressure-in-otolaryngology-clinic
#33
JOURNAL ARTICLE
Samuel Altonji, Amanda Del Risco, Kayla W Kilpatrick, Maragatha Kuchibhatla, Ralph Abi Hachem, David W Jang
OBJECTIVES: Identify demographic and clinical characteristics that may help differentiate non-rhinogenic facial pain or pressure (NRFP) from sinusitis. STUDY DESIGN: Retrospective single-institution study. SETTING: Tertiary Care Center Rhinology Clinic. METHODS: All patients presenting with a complaint of facial pain or pressure over a 3-year period were included. Patients were categorized into either NRFP or sinusitis groups based on computed tomography imaging and nasal endoscopy...
January 14, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38217558/normalization-of-the-suppression-head-impulse-test-shimp-and-its-correlation-with-the-head-impulse-test-himp-in-healthy-adults
#34
JOURNAL ARTICLE
Suheda Baran, Gulce Kirazli, Pelin Pistav Akmese, Nese Celebisoy, Tayfun Kirazli
OBJECTIVE: In our study, it was aimed to compare vestibulo-ocular reflex (VOR) gain and saccade parameters in HIMP and SHIMP tests between gender, right and left ears, and age groups in healthy adults and to examine the correlation between the tests regarding these parameters. METHODS: The study included a total of 100 healthy participants aged 18-65 and without complaints of hearing loss, dizziness, lightheadedness, and/or imbalance. Participants underwent HIMP and SHIMP tests, respectively...
2024: Journal of Vestibular Research: Equilibrium & Orientation
https://read.qxmd.com/read/38187303/impact-on-the-first-year-of-life-of-newborns-with-gestational-infection-by-sars-cov-2-analysis-of-auditory-effects
#35
JOURNAL ARTICLE
Lorena Sanz López, Joaquin Lora Díaz, Raúl Castañeda-Vozmediano, Nieves Mata-Castro
INTRODUCTION: One of the causes of congenital hearing loss are infections suffered by the mother during pregnancy. The objective of this study was to investigate the effects on hearing in newborns to SARS-CoV-2 seropositive mothers during pregnancy. We also studied the hearing impact in the first year of life of the newborns to investigate whether neonatal infection produced a risk of infantile sensorineural hearing loss. MATERIAL AND METHODS: All children born in our center whose mother had been infected with SARS-CoV-2 positive COVID were included and were audiologically studied at two and a half months and at one year of life...
January 15, 2024: Heliyon
https://read.qxmd.com/read/38178864/real-life-experience-with-sonidegib-for-locally-advanced-basosquamous-carcinoma-a-case-series
#36
Enrico Bocchino, Simone Cappilli, Gerardo Palmisano, Andrea Paradisi, Alfredo Piccerillo, Alessandro Di Stefani, Ketty Peris
INTRODUCTION: Basosquamous carcinoma is an uncommon subtype of basal cell carcinoma (BCC), characterized by aggressive local growth and metastatic potential, that mainly develops on the nose, perinasal area, and ears, representing 1.2-2.7% of all head-neck keratinocyte carcinomas. Although systemic therapy with hedgehog inhibitors (HHIs) represents the first-line medical treatment in advanced BCC, to date, no standard therapy for advanced basosquamous carcinoma has been established. Herein, we reported a case series of patients affected by locally advanced basosquamous carcinomas, who were treated with HHIs...
2024: Case Reports in Dermatology
https://read.qxmd.com/read/38175662/hearing-loss-hearing-aid-use-and-risk-of-dementia-in-older-adults
#37
JOURNAL ARTICLE
Manuella Lech Cantuaria, Ellen Raben Pedersen, Frans Boch Waldorff, Lene Wermuth, Kjeld Møller Pedersen, Aslak Harbo Poulsen, Ole Raaschou-Nielsen, Mette Sørensen, Jesper Hvass Schmidt
IMPORTANCE: Hearing loss has been suggested as a risk factor for dementia, but there is still a need for high-quality research to better understand the association between these 2 conditions and the underlying causal mechanisms and treatment benefits using larger cohorts and detailed data. OBJECTIVE: To investigate the association between hearing loss and incident dementia, as well as how hearing aid use contributes to this association. DESIGN, SETTING, AND PARTICIPANTS: This population-based cohort study was conducted in Southern Denmark between January 2003 and December 2017 and included all residents 50 years and older...
February 1, 2024: JAMA Otolaryngology—Head & Neck Surgery
https://read.qxmd.com/read/38127339/step-serial-sectioning-in-head-and-neck-squamous-cell-carcinoma-of-unknown-primary
#38
MULTICENTER STUDY
John C Hardman, Kevin Harrington, Ben O'Leary, Max Robinson, Vinidh Paleri
IMPORTANCE: Patients with suspected head and neck squamous cell carcinoma of unknown primary (HNSCCUP) may undergo tonsillectomy and tongue base mucosectomy (TBM) to help identify clinicoradiologically occult primary disease. It is hypothesized that when these diagnostic specimens are analyzed, conventional histopathological (CH) techniques risk missing small primary tumors that may be hidden in the tissue blocks. OBJECTIVE: To establish the outcomes of a step serial sectioning (SSS) histopathological technique vs CH when analyzing diagnostic tissue specimens from TBM and tonsillectomy performed for HNSCCUP...
February 1, 2024: JAMA Otolaryngology—Head & Neck Surgery
https://read.qxmd.com/read/38094713/association-between-culture-and-the-preference-for-and-perceptions-of-11-routes-of-medicine-administration-a-survey-in-21-countries-and-regions
#39
JOURNAL ARTICLE
Sudaxshina Murdan, Li Wei, Diana A van Riet-Nales, Abyot Endale Gurmu, Stella Folajole Usifoh, Adriana-Elena Tăerel, Ayca Yıldız-Peköz, Dušanka Krajnović, Lilian M Azzopardi, Tina Brock, Ana I Fernandes, André Luis Souza Dos Santos, Berko Panyin Anto, Thibault Vallet, Eunkyung Euni Lee, Kyeong Hye Jeong, Marwan Akel, Eliza Tam, Daisy Volmer, Tawfik Douss, Sharvari Shukla, Shigeo Yamamura, Xiaoe Lou, Bauke H G van Riet, Cyril O Usifoh, Mahama Duwiejua, Fabrice Ruiz, Adrian Furnham
Medicines can be taken by various routes of administration. These can impact the effects and perceptions of medicines. The literature about individuals' preferences for and perceptions of the different routes of administration is sparse, but indicates a potential influence of culture. Our aim was to determine: (i) any association between one's culture and one's preferred route of medicine administration and (ii) individual perceptions of pain, efficacy, speed of action and acceptability when medicines are swallowed or placed in the mouth, under the tongue, in the nose, eye, ear, lungs, rectum, vagina, on the skin, or areinjected...
December 2023: Explor Res Clin Soc Pharm
https://read.qxmd.com/read/38073288/reevaluation-of-the-protein-requirement-in-chinese-elderly-adults-without-sarcopenia-with-the-indicator-amino-acid-oxidation-technique
#40
JOURNAL ARTICLE
Wenxuan Wu, Yanhong Zhang, Hui Ma, Jiaxi Lu, Fengge Chen, Haisong Zhou, Shuhui Nie, Yunqi Yang, Rui Wang, Weixiao Yue, Min Li, Lichen Yang
It is now generally believed that elderly may have slightly higher dietary protein requirements than those of the young-middle-aged adults. We have previously conducted related studies by the indicator amino acid oxidation (IAAO) technique, but more research data are needed to revise the protein requirements of the elderly. The main objective was to reevaluate the dietary protein requirements of healthy Chinese adults (65-80y) without sarcopenia by using the IAAO technique. Nine healthy adult men and seven healthy adult women participated in the study, with protein intakes ranging from 0...
December 11, 2023: British Journal of Nutrition
keyword
keyword
59617
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.