keyword
MENU ▼
Read by QxMD icon Read
search

PCP

keyword
https://www.readbyqxmd.com/read/28923810/an-innovative-community-based-model-for-improving-preventive-care-in-rural-counties
#1
Zsolt J Nagykaldi, Dewey Scheid, Daniel Zhao, Bhawani Mishra, Tracy Greever-Rice
OBJECTIVE: This quasi-experimental pilot study aimed to implement and evaluate a sustainable, rural community-based patient outreach model for preventive care provided through primary care practices (PCPs) located in a rural county in Oklahoma. A Wellness Coordinator (WC) working with PCPs, the county health department, the county hospital, and a health information exchange (HIE) organization helped county residents receive evidence-based preventive services. METHODS: The WC used a community wellness registry connected to electronic medical records via HIE and called patients at the county level based on PCP-prioritized and tailored protocols...
September 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28923514/cell-polarity-and-planar-cell-polarity-pcp-in-spermatogenesis
#2
REVIEW
Haiqi Chen, Dolores D Mruk, Wing-Yee Lui, Chris K C Wong, Will M Lee, C Yan Cheng
In adult mammalian testes, spermatids, most notably step 17-19 spermatids in stage IV-VIII tubules, are aligned with their heads pointing toward the basement membrane and their tails toward the tubule lumen. On the other hand, these polarized spermatids also align across the plane of seminiferous epithelium, mimicking planar cell polarity (PCP) found in other hair cells in cochlea (inner ear). This orderly alignment of developing spermatids during spermiogenesis is important to support spermatogenesis, such that the maximal number of developing spermatids can be packed and supported by a fixed population of differentiated Sertoli cells in the limited space of the seminiferous epithelium in adult testes...
September 15, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28923070/univariate-and-multivariate-spatial-models-of-health-facility-utilisation-for-childhood-fevers-in-an-area-on-the-coast-of-kenya
#3
Paul O Ouma, Nathan O Agutu, Robert W Snow, Abdisalan M Noor
BACKGROUND: Precise quantification of health service utilisation is important for the estimation of disease burden and allocation of health resources. Current approaches to mapping health facility utilisation rely on spatial accessibility alone as the predictor. However, other spatially varying social, demographic and economic factors may affect the use of health services. The exclusion of these factors can lead to the inaccurate estimation of health facility utilisation. Here, we compare the accuracy of a univariate spatial model, developed only from estimated travel time, to a multivariate model that also includes relevant social, demographic and economic factors...
September 18, 2017: International Journal of Health Geographics
https://www.readbyqxmd.com/read/28921381/pentachlorophenol-molecule-design-with-lower-bioconcentration-through-3d-qsar-associated-with-molecule-docking
#4
Xiaolei Wang, Zhenhua Chu, Jiawen Yang, Yu Li
A three-dimensional quantitative structure activity relationship (3D-QSAR) model is built by using a comparative molecular similarity indices analysis (CoMSIA) technique with an experimentally determined logarithm of bioconcentration factors (logBCFs) for 36 phenols in fish. Meanwhile, with the pentachlorophenol (PCP) molecule as target molecules, contributions of the molecular fields indicate that the electrostatic fields are the main influences on the bioconcentration of the PCP molecule. Based on the analytical results of CoMSIA contour map of PCP and PCP molecular docking with SOD protease (PDB ID: 4A7T), the R6 substituent positions of PCP were modified to give seven new modified PCP molecules with low bioconcentration in this paper...
September 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28918624/synthesis-of-oligodiacetylene-derivatives-from-flexible-porous-coordination-frameworks
#5
Yu-Ichi Fujiwara, Kentaro Kadota, Sanjog S Nagarkar, Prof Norio Tobori, Susumu Kitagawa, Satoshi Horike
Oligodiacetylenes (ODAs) with alternating ene-yne conjugated structure is one of the significant materials for optical and electronic properties. Due to the low solubility of ODAs in common solvents, the synthetic approaches are limited. Here we disclose a new synthetic approach of ODAs without side alkyl chain using porous coordination polymer (PCP) as a sacrificial template. 1,2-bis(4-pyridyl)butadiyne which work as a monomer were embedded in the flexible frame-work of PCP, and ODAs were synthesized via utilization of the anisotropic thermal expansion (ATE) of PCP crystal...
September 16, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28917392/description-of-a-multi-university-education-and-collaborative-care-child-psychiatry-access-program-new-york-state-s-cap-pc
#6
D L Kaye, V Fornari, M Scharf, W Fremont, R Zuckerbrot, C Foley, T Hargrave, B A Smith, J Wallace, G Blakeslee, J Petras, S Sengupta, J Singarayer, A Cogswell, I Bhatia, P Jensen
OBJECTIVE: Although, child mental health problems are widespread, few get adequate treatment, and there is a severe shortage of child psychiatrists. To address this public health need many states have adopted collaborative care programs to assist primary care to better assess and manage pediatric mental health concerns. This report adds to the small literature on collaborative care programs and describes one large program that covers most of New York state. PROGRAM DESCRIPTION: CAP PC, a component program of New York State's Office of Mental Health (OMH) Project TEACH, has provided education and consultation support to primary care providers covering most of New York state since 2010...
September 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28915904/tiga-cub-manualised-psychoanalytic-child-psychotherapy-versus-treatment-as-usual-for-children-aged-5-11-years-with-treatment-resistant-conduct-disorders-and-their-primary-carers-study-protocol-for-a-randomised-controlled-feasibility-trial
#7
Elizabeth Edginton, Rebecca Walwyn, Kayleigh Burton, Robert Cicero, Liz Graham, Sadie Reed, Sandy Tubeuf, Maureen Twiddy, Alex Wright-Hughes, Lynda Ellis, Dot Evans, Tom Hughes, Nick Midgley, Paul Wallis, David Cottrell
BACKGROUND: The National Institute for Health and Care Excellence (NICE) recommends evidence-based parenting programmes as a first-line intervention for conduct disorders (CD) in children aged 5-11 years. As these are not effective in 25-33% of cases, NICE has requested research into second-line interventions. Child and Adolescent Psychotherapists (CAPTs) address highly complex problems where first-line treatments have failed and there have been small-scale studies of Psychoanalytic Child Psychotherapy (PCP) for CD...
September 15, 2017: Trials
https://www.readbyqxmd.com/read/28910099/classical-force-fields-tailored-for-qm-applications-is-it-really-a-feasible-strategy
#8
Oliviero Andreussi, Ingrid Guarnetti Prandi, Marco Campetella, Giacomo Prampolini, Benedetta Mennucci
Classical molecular dynamics is more and more often coupled to quantum mechanical based techniques as statistical tool to sample configurations of molecular systems embedded in complex environments. Nonetheless, the classical potentials describing the molecular systems are seldom parameterized to reproduce electronic processes, such as electronic excitations, which are instead very sensitive to the underlining description of the molecular structure. Here we analyze the challenging case of the peridinin molecule, a natural apocarotenoid responsible for the light-harvesting process in the PCP antenna protein of dinoflagellates...
September 14, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28900821/reliability-of-physician-level-measures-of-patient-experience-in-primary-care
#9
Joshua J Fenton, Anthony Jerant, Richard L Kravitz, Klea D Bertakis, Daniel J Tancredi, Elizabeth M Magnan, Peter Franks
BACKGROUND: Patient experience measures are widely used to compare performance at the individual physician level. OBJECTIVE: To assess the impact of unmeasured patient characteristics on visit-level patient experience measures and the sample sizes required to reliably measure patient experience at the primary care physician (PCP) level. DESIGN: Repeated cross-sectional design. SETTING: Academic family medicine practice in California...
September 12, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28898810/the-european-water-based-environmental-quality-standard-for-pentachlorophenol-is-not-protective-of-benthic-organisms
#10
Roberta Bettinetti, Annette Kopp-Schneider, Davide A L Vignati
Risk management of toxic substances is often based on Environmental Quality Standards (EQS) set for the water compartment, assuming they will also protect benthic organisms. In the absence of experimental data, EQS for sediments can be estimated by the equilibrium partitioning approach. The present study investigates whether this approach is protective of benthic organisms against pentachlorophenol (PCP), a legacy contaminant and EU priority substance still used in some parts of the world. Three freshwater species of invertebrates with different life cycles and feeding behaviors (the oligochaetes Lumbriculus variegatus, Tubifex tubifex and the dipteran insect Chironomus riparius) were exposed to PCP spiked sediments (2...
September 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28893787/efficacy-and-toxicity-of-low-dose-trimethoprim-sulfamethoxazole-for-the-treatment-of-pneumocystis-pneumonia-in-patients-without-human-immunodeficiency-virus-infection-a-four-center-retrospective-study
#11
Makoto Kosaka, Atsuhito Ushiki, Yuichi Ikuyama, Kazuya Hirai, Akemi Matsuo, Tsutomu Hachiya, Masayuki Hanaoka
Background and objectives: The dose of trimethoprim-sulfamethoxazole (TMP-SMX) for the treatment of pneumocystis pneumonia (PCP) in patients without human immunodeficiency virus (HIV) infection has not been verified. The aim of this study was to investigate the efficacy and toxicity of low-dose TMP-SMX regimen in such patients.Methods: A retrospective study was conducted in four hospitals. We reviewed the medical records of patients with PCP but not HIV (non-HIV-PCP), who were treated with TMP-SMX between 2003 and 2016...
September 11, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28892080/differential-effects-on-lung-and-bone-metastasis-of-breast-cancer-by-wnt-signalling-inhibitor-dkk1
#12
Xueqian Zhuang, Hao Zhang, Xiaoyan Li, Xiaoxun Li, Min Cong, Fangli Peng, Jingyi Yu, Xue Zhang, Qifeng Yang, Guohong Hu
Metastatic cancer is a systemic disease, and metastasis determinants might elicit completely different effects in various target organs. Here we show that tumour-secreted DKK1 is a serological marker of breast cancer metastasis organotropism and inhibits lung metastasis. DKK1 suppresses PTGS2-induced macrophage and neutrophil recruitment in lung metastases by antagonizing cancer cell non-canonical WNT/PCP-RAC1-JNK signalling. In the lungs, DKK1 also inhibits WNT/Ca(2+)-CaMKII-NF-κB signalling and suppresses LTBP1-mediated TGF-β secretion of cancer cells...
September 11, 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/28886595/personal-care-product-use-in-men-and-urinary-concentrations-of-select-phthalate-metabolites-and-parabens-results-from-the-environment-and-reproductive-health-earth-study
#13
Feiby L Nassan, Brent A Coull, Audrey J Gaskins, Michelle A Williams, Niels E Skakkebaek, Jennifer B Ford, Xiaoyun Ye, Antonia M Calafat, Joseph M Braun, Russ Hauser
BACKGROUND: Personal care products (PCPs) are exposure sources to phthalates and parabens; however, their contribution to men's exposure is understudied. OBJECTIVES: We examined the association between PCP use and urinary concentrations of phthalate metabolites and parabens in men. METHODS: In a prospective cohort, at multiple study visits, men self-reported their use of 14 PCPs and provided a urine sample (2004-2015, Boston, MA). We measured urinary concentrations of 9 phthalate metabolites and methylparaben, propylparaben, and butylparaben...
August 18, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28886250/dectin-2-is-a-c-type-lectin-receptor-that-recognizes-pneumocystis-and-participates-in-innate-immune-responses
#14
Theodore J Kottom, Deanne M Hebrink, Paige E Jenson, Paige L Marsolek, Marcel Wüthrich, Huafeng Wang, Bruce Klein, Sho Yamasaki, Andrew H Limper
Pneumocystis remains an important fungal pathogen causing life-threatening pneumonia in patients with AIDS and malignancy. Lung fungal pathogens are recognized by C-type Lectin Receptors (CLRs), which bind specific ligands and stimulate innate immune responses. Previously, a role for the CLR Dectin-1 has been shown to mediate immune responses to Pneumocystis spp. For this reason, we investigated a potential role for Dectin-2. Rats with Pneumocystis pneumonia (PCP) exhibited elevated Dectin-2 mRNA levels. Soluble Dectin-2 CRD fusions protein showed binding to intact Pneumocystis carinii (Pc) and to native Pneumocystis major surface glycoprotein/glycoprotein A (Msg/gpA)...
September 8, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28885142/sonic-hedgehog-switches-on-wnt-planar-cell-polarity-signaling-in-commissural-axon-growth-cones-by-reducing-levels-of-shisa2
#15
Keisuke Onishi, Yimin Zou
Commissural axons switch on responsiveness to Wnt attraction during midline crossing and turn anteriorly only after exiting the floor plate. We report here that Sonic Hedgehog (Shh)-Smoothened signaling downregulates Shisa2, which inhibits the glycosylation and cell surface presentation of Frizzled3 in rodent commissural axon growth cones. Constitutive Shisa2 expression causes randomized turning of post-crossing commissural axons along the anterior-posterior (A-P) axis. Loss of Shisa2 led to precocious anterior turning of commissural axons before or during midline crossing...
September 8, 2017: ELife
https://www.readbyqxmd.com/read/28879093/refractory-acute-respiratory-failure-due-to-pneumocystis-jiroveci-pcp-and-cytomegalovirus-cmv-pneumonitis-a-case-report-and-review-of-literature
#16
Kairav Shah, Kartikeya Cherabuddi, Stacy G Beal, Gautam Kalyatanda
BACKGROUND: Opportunistic infections with Pneumocystis jiroveci pneumonia (PCP) are common in patients with HIV (human immunodeficiency virus) and are encountered once the CD4 count decreases below 200 cells/mm3. Cytomegalovirus (CMV) tends to cause disease once the CD4 count drops below 50 cells/mm3. CMV pneumonitis is not common in this population. However, detecting its presence in broncho-alveolar lavage (BAL) fluid has been associated with increased morbidity and mortality. The role of antiviral therapy against CMV remains unclear...
2017: IDCases
https://www.readbyqxmd.com/read/28878936/primary-care-physicians-utilization-of-type-2-diabetes-screening-guidelines-and-referrals-to-behavioral-interventions-a-survey-linked-retrospective-study
#17
Sandhya Mehta, Michelle Mocarski, Tami Wisniewski, Karin Gillespie, K M Venkat Narayan, Kathleen Lang
OBJECTIVE: To assess primary care physicians' (PCPs) knowledge of type 2 diabetes screening guidelines (American Diabetes Association (ADA) and 2008 US Preventive Services Task Force (USPSTF)), the alignment between their self-reported adherence and actual practice, and how often PCPs recommended diabetes prevention and self-management education programs (DPP/DSME). RESEARCH DESIGN AND METHODS: An online survey of PCPs to understand knowledge and adherence toward use of USPSTF/ADA guidelines and recommendation of DPP/DSME...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28875593/implementing-an-evidence-based-clinical-decision-support-tool-to-improve-the-detection-evaluation-and-referral-patterns-of-adult-chronic-kidney-disease-patients-in-primary-care
#18
Mary E Regan
BACKGROUND AND PURPOSE: Chronic kidney disease (CKD) is undertreated and under-recognized in primary care. The majority of primary care providers (PCPs) are not aware or knowledgeable of current CKD guidelines. The purpose of this project was to develop a quality improvement intervention for PCPs through the delivery of evidence-based guidelines at the point of care. METHODS: An evidence-based clinical algorithm was developed in the electronic medical record for providers to access within one organization comprising 11 primary care offices with 80 PCPs...
September 6, 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28872251/room-temperature-synthesis-and-binding-studies-of-solution-processable-histamine-imprinted-microspheres
#19
Edwin F Romano, Clovia I Holdsworth, Joselito P Quirino, Regina C So
Accurate quantification of histamine levels in food and in biological samples is important for monitoring the quality of food products and for the detection of pathophysiological conditions. In this study, solution processable histamine-imprinted microspheres were synthesized at 30°C via dilute free radical phototochemical polymerization technique using ethylene glycol dimethacrylate (EGDMA) as the crosslinker and methacrylic acid (MAA) as the monomer. The processability of the resulting polymer is dictated by the monomer feed concentration (eg, 4 wt% 80:20 EGDMA:MAA formulation) and solvent (acetonitrile)...
September 5, 2017: Journal of Molecular Recognition: JMR
https://www.readbyqxmd.com/read/28870732/processes-and-outcomes-of-congestive-heart-failure-care-by-different-types-of-primary-care-models
#20
Yong-Fang Kuo, Deepak Adhikari, Chiemeziem G Eke, James S Goodwin, Mukaila A Raji
BACKGROUND: Having nurse practitioners (NPs) as primary care providers for patients with congestive heart failure (CHF) is one way to address the growing shortage of primary care physicians (PCPs). METHODS AND RESULTS: We used inverse probability of treatment weighted with propensity score to examine the processes and outcomes of care for patients under three care models. Approximately 72.9%, 0.8%, and 26.3% of CHF patients received care under the PCP model, the NP model, and the shared care model, respectively...
September 1, 2017: Journal of Cardiac Failure
keyword
keyword
59612
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"