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Sepsis CKD ESRD Dialysis

Vina Tresa, Afshan Yaseen, Ali Asghar Lanewala, Seema Hashmi, Sabeeta Khatri, Irshad Ali, Muhammed Mubarak
BACKGROUND: The reported prevalence rates and etiologies of acute kidney injury (AKI) are quite variable in different regions of the world. The current study was planned to determine the etiology, clinical profile, and short-term outcome of pediatric AKI at our hospital. METHODS: A prospective, observational study was carried out from April 2014 to March 2015. All pediatric patients (1 month to ≤15 years) diagnosed as AKI using modified pRIFLE criteria were studied and followed for 3 months to document short-term outcome...
October 21, 2016: Renal Failure
Helen I McDonald, Dorothea Nitsch, Elizabeth R C Millett, Alan Sinclair, Sara L Thomas
BACKGROUND: We aimed to examine whether pre-existing impaired estimated glomerular filtration rate (eGFR) and proteinuria were associated with mortality following community-acquired pneumonia or sepsis among people aged ≥ 65 years with diabetes mellitus, without end-stage renal disease. METHODS: Patients were followed up from onset of first community-acquired pneumonia or sepsis episode in a cohort study using large, linked electronic health databases. Follow-up was for up to 90 days, unlimited by hospital discharge...
June 2015: Nephrology, Dialysis, Transplantation
Kengo Sasaki, Seisuke Sakamoto, Hajime Uchida, Takanobu Shigeta, Masatoshi Matsunami, Hiroyuki Kanazawa, Akinari Fukuda, Atsuko Nakazawa, Mai Sato, Shuichi Ito, Reiko Horikawa, Tadashi Yokoi, Noriyuki Azuma, Mureo Kasahara
Several transplant strategies for PH1 have been proposed, and LT is performed to correct the metabolic defects. The patients with PH1 often suffer from ESRD and require simultaneous LKT, which leads to a long wait due to the shortage of suitable organ donors. Five patients with PH1 underwent LDLT at our institute. Three of the five patients were under dialysis before LDLT, while the other two patients were categorized as CKD stage 3. An isolated LDLT was successfully performed in all but our first case, who had complicated postoperative courses and consequently died due to sepsis after retransplantation...
February 2015: Pediatric Transplantation
M A C Onuigbo, N T Onuigbo, C G Musso
Despite decades of research, a full understanding of chronic kidney disease (CKD)-end stage renal disease (ESRD) progression remains elusive. The common consensus is a predictable, linear, progressive and time-dependent decline of CKD to ESRD. Acute kidney injury (AKI) on CKD is usually assumed to be transient, with recovery as the expected outcome. AKI-ESRD association in current nephrology literature is blamed on the so-called "residual confounding." We had previously described a relationship between AKI events and rapid onset yet irreversible ESRD happening in a continuum in a high-risk CKD cohort...
March 2014: Indian Journal of Nephrology
Jordan M Cloyd, Yifei Ma, John M Morton, Manjula Kurella Tamura, George A Poultsides, Brendan C Visser
INTRODUCTION: The impact of chronic kidney disease (CKD) and end-stage renal disease on outcomes following major abdominal surgery is not well defined. MATERIALS AND METHODS: The 2008 NSQIP database was queried to identify adult patients undergoing complex abdominal surgery (major colorectal, hepatobiliary, pancreatic, gastric, and esophageal operations). Thirty-day morbidity and mortality in patients on hemodialysis (HD) versus patients not on HD were compared...
March 2014: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Y Okunola, O Ayodele, P Akinwusi, B Gbadegesin, R Oluyombo
BACKGROUND: HASH(0x41fb838) OBJECTIVE: To provide information on the challenges of haemodialysis in a resource limited setting in South-Western Nigeria. METHODS: This is a 5 year audit of all haemodialysis sessions carried out at the renal unit of the Ladoke Akintola University Teaching Hospital (LAUTECH), Osogbo, Nigeria. RESULTS: A total of 225 patients were offered haemodialysis (HD) during this period with age range of 10 to 85 years (mean age of 49 years±16...
March 2013: Ghana Medical Journal
Hans-Joachim Anders, Kirstin Andersen, Bärbel Stecher
Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are associated with systemic inflammation and acquired immunodeficiency, which promote cardiovascular disease, body wasting, and infections as leading causes of death. This phenomenon persists despite dialysis-related triggers of immune deregulation having been largely eliminated. Here we propose a potential immunoregulatory role of the intestinal microbiota in CKD/ESRD. We discuss how the metabolic alterations of uremia favor pathogen overgrowth (dysbiosis) in the gut and an increased translocation of living bacteria and bacterial components...
June 2013: Kidney International
Amal A Hassanien, Fahdah Al-Shaikh, Eszter P Vamos, Ghasem Yadegarfar, Azeem Majeed
OBJECTIVES: To describe the epidemiology of end stage renal disease (ESRD). DESIGN: Mixed-methods systematic review. SETTING: The countries of the Gulf Cooperation Council (GCC) which consist of Saudi Arabia, the United Arab Emirates, Kuwait, Qatar, Bahrain, and Oman. PARTICIPANTS: Defined to have ESRD or patients on regular dialysis for a minimum dialysis period of at least three months. Since many outcomes were reviewed, studies that estimated the incidence and prevalence of ESRD as outcomes should not have defined the study population as ESRD population or patients on regular dialysis...
June 2012: JRSM Short Reports
Christine Tompkins, Rhondalyn McLean, Alan Cheng, Jeffrey A Brinker, Joseph E Marine, Saman Nazarian, David D Spragg, Sunil Sinha, Henry Halperin, Gordon F Tomaselli, Ronald D Berger, Hugh Calkins, Charles A Henrikson
INTRODUCTION: Patients with chronic kidney disease (CKD) have increased morbidity following invasive procedures. We hypothesized that patients with CKD have higher complication rates following device implantation than patients with normal renal function. METHODS: We reviewed the medical records of patients undergoing ICD or pacemaker implantation from August 2004 to August 2007. The estimated glomerular filtration rate (GFR) was calculated using the Cockroft-Gault equation...
October 2011: Journal of Cardiovascular Electrophysiology
G Spasovski
(Full text is available at Nephrologists and internists who work in the field of renal replacement therapy with dialysis had an opportunity to attend the continuing medical (nephrology) education (CME) on the subject of: Diagnostic and treatment options in CKD in the new millennium. The course was held on 25 April 2009, in the premises of the Macedonian Academy of Sciences and Arts, in honour of the 70th anniversary of Academician Momir Polenakovic, one of the founders of the Macedonian nephrology...
July 2010: Prilozi
Anan Chuasuwan, Pongsathorn Gojaseni, Anutra Chittinandana
OBJECTIVE: Continuous veno-venous hemofiltration (CVVH) is a mode of renal replacement therapy in critically ill patients that has gained popularity all over the world. The authors reviewed one-year experience with CVVH in intensive care units (ICUs) of Bhumibol Adulyadej Hospital. The objectives of this study were to describe the characteristics of the patients and demonstrate the association between various factors and outcome. MATERIAL AND METHOD: The medical records of 45 patients who underwent CVVH treatment were analyzed...
August 2006: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Sakina B Naqvi, Allan J Collins
Infectious complications in individuals with chronic kidney disease (CKD) pose a significant source of morbidity and mortality. The overall scope of major infectious complications has, however, received little attention even though some of these events may be preventable. We reviewed infectious hospitalization rates in the CKD and end-stage renal disease (ESRD) populations, comparing them with the non-CKD and non-ESRD groups. We also reviewed preventive vaccination rates for influenza, pneumonia, and pneumococcal pneumonia to assess areas of potential improvement...
July 2006: Advances in Chronic Kidney Disease
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