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https://www.readbyqxmd.com/read/28214001/comparison-of-pulmonary-venous-and-left-atrial-remodeling-in-patients-with-atrial-fibrillation-with-hypertrophic-cardiomyopathy-versus-with-hypertensive-heart-disease
#1
Kentaro Yoshida, Hideyuki Hasebe, Yasuaki Tsumagari, Hidekazu Tsuneoka, Mari Ebine, Yoshiko Uehara, Yoshihiro Seo, Kazutaka Aonuma, Noriyuki Takeyasu
Left ventricular diastolic dysfunction in hypertrophic cardiomyopathy (HC) increases susceptibility to atrial fibrillation. Although phenotypical characteristics of the hypertrophied left ventricle are clear, left atrial (LA) and pulmonary venous (PV) remodeling has rarely been investigated. This study aimed to identify differences in LA and PV remodeling between HC and hypertensive heart disease (HHD) using 3-dimensional computed tomography. Included were 33 consecutive patients with HC, 25 with HHD, and 29 without any co-morbidities who were referred for catheter ablation of atrial fibrillation...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28212817/in-vivo-toxicity-of-copper-oxide-lead-oxide-and-zinc-oxide-nanoparticles-acting-in-different-combinations-and-its-attenuation-with-a-complex-of-innocuous-bio-protectors
#2
Ilzira A Minigalieva, Boris A Katsnelson, Vladimir G Panov, Larisa I Privalova, Anatoly N Varaksin, Vladimir B Gurvich, Marina P Sutunkova, Vladimir Ya Shur, Ekaterina V Shishkina, Irene E Valamina, Ilya V Zubarev, Oleg H Makeyev, Ekaterina Y Meshtcheryakova, Svetlana V Klinova
Stable suspensions of metal oxide nanoparticles (Me-NPs) obtained by laser ablation of 99.99% pure copper, zinc or lead under a layer of deionized water were used separately, in three binary combinations and a triple combination in two independent experiments on rats. In one of the experiments the rats were instilled with Me-NPs intratracheally (i.t.) (for performing a broncho-alveolar lavage in 24hrs to estimate the cytological and biochemical indices of the response of the lower airways), while in the other, Me-NPs were repeatedly injected intraperitoneally (i...
February 14, 2017: Toxicology
https://www.readbyqxmd.com/read/28209504/myopic-surface-ablation-in-asymmetrical-topographies-refractive-results-and-theoretical-corneal-elastic-response
#3
Luis F Brenner, Antonio Renna, Anna Pandolfi, Francisco C Martínez, Jorge L Alió
PURPOSE: To evaluate refractive results and the theoretical elastic response of photorefractive keratectomy in eyes with asymmetrical corneal surface and to compare such outcomes with a control-matched group of normal topographies. DESIGN: Retrospective interventional case series with matched comparison group. METHODS: 30 eyes with superior-inferior dioptric difference (SI index) > 1.40 D, were compared to 30 eyes with normal topographies...
February 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28197998/laser-assisted-subepithelial-keratectomy-lasek-versus-laser-assisted-in-situ-keratomileusis-lasik-for-correcting-myopia
#4
REVIEW
Jocelyn Kuryan, Anjum Cheema, Roy S Chuck
BACKGROUND: Near-sightedness, or myopia, is a condition in which light rays entering the eye along the visual axis focus in front of the retina, resulting in blurred vision. Myopia can be treated with spectacles, contact lenses, or refractive surgery. Options for refractive surgery include laser-assisted subepithelial keratectomy (LASEK) and laser-assisted in-situ keratomileusis (LASIK). Both procedures utilize a laser to shape the corneal tissue (front of the eye) to correct refractive error, and both create flaps before laser treatment of corneal stromal tissue...
February 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28192653/double-network-structured-graphene-oxide-containing-nanogels-as-photothermal-agents-for-the-treatment-of-colorectal-cancer
#5
Calogero Fiorica, Nicolò Mauro, Giovanna Pitarresi, Cinzia Scialabba, Fabio S Palumbo, Gaetano Giammona
Here, we reported the production of hyaluronic acid/polyaspartamide-based double-network nanogels for the potential treatment of colorectal carcinoma. Graphene oxide, thanks to the huge aromatic surface area, allows to easily load high amount of irinotecan (33.0 % w/w) and confers to the system hyperthermic properties when irradiated with a near infrared (NIR) laser beam. We demonstrate that the release of antitumor drug is influenced both by the pH of the external medium and the NIR irradiation process. In vitro biological studies, conducted on human colon cancer cells (HCT 116), revealed that nanogels are uptaken by the cancer cells and, in the presence of the antitumor drug, can produce a synergistic hyperthermic/cytotoxic effect...
February 13, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28192591/lasik-enhancement-clinical-and-surgical-management
#6
Majid Moshirfar, Naz Jehangir, Carlton R Fenzl, Michael McCaughey
PURPOSE: To review refractive regression and current therapeutic options for patients who have residual refractive error after LASIK. METHODS: An extensive literature search using PubMed was performed for terms such as "LASIK," "PRK," "enhancement," "overcorrection," "undercorrection," "re-lift," "mini-flap," and related terms. RESULTS: The presence of residual refractive error following LASIK is a challenging situation. After excluding anatomical causes (eg, ocular surface disease, cataract, and macular pathology) and intraoperative flap complications, evaluation of the residual stromal bed must be performed...
February 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28192587/advanced-surface-ablation-with-a-new-software-for-the-reduction-of-ablation-irregularities
#7
Paolo Vinciguerra, Fabrizio I Camesasca, Riccardo Vinciguerra, Samuel Arba-Mosquera, Ingrid Torres, Emanuela Morenghi, J Bradley Randleman
PURPOSE: To compare visual outcomes and postoperative aberrations after surface ablation performed with a 750-Hz versus a 1,050-Hz excimer laser coupled with an ablation software designed to reduce corneal surface irregularity. METHODS: Retrospective comparative trial of myopic eyes that had refractive surgery consecutively treated with transepithelial advanced surface ablation with a 750-Hz excimer laser (750 group) versus a 1,050-Hz excimer laser coupled with the Smart Pulse Technology ablation software (SPT group)...
February 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28192586/three-year-stability-of-posterior-corneal-elevation-after-small-incision-lenticule-extraction-smile-for-moderate-and-high-myopia
#8
Yu Zhao, Weijun Jian, Yingjun Chen, Michael C Knorz, Xingtao Zhou
PURPOSE: To investigate long-term changes in posterior corneal elevation after small incision lenticule extraction (SMILE). METHODS: Thirty-six eyes of 20 patients (7 male, 13 female) who underwent SMILE were recruited for this prospective consecutive study. The mean preoperative manifest spherical equivalent was -6.24 ± 1.47 diopters (D) (range: -3.88 to -8.75 D). Posterior corneal surfaces were measured by a Scheimpflug camera (Pentacam; Oculus Optikgeräte GmbH, Wetzlar, Germany) preoperatively and at 1 month, 6 months, 12 months, 2 years, and 3 years after surgery...
February 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28192085/influence-of-peptide-transporter-2-pept2-on-the-distribution-of-cefadroxil-in-mouse-brain-a-microdialysis-study
#9
Xiaomei Chen, Richard F Keep, Yan Liang, Hao-Jie Zhu, Margareta Hammarlund-Udenaes, Yongjun Hu, David E Smith
Peptide transporter 2 (PEPT2) is a high-affinity low-capacity transporter belonging to the proton-coupled oligopeptide transporter family. Although many aspects of PEPT2 structure-function are known, including its localization in choroid plexus and neurons, its regional activity in brain, especially extracellular fluid (ECF), is uncertain. In this study, the pharmacokinetics and regional brain distribution of cefadroxil, a ß-lactam antibiotic and PEPT2 substrate, were investigated in wildtype and Pept2 null mice using in vivo intracerebral microdialysis...
February 10, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28191931/laser-synthesis-and-processing-of-colloids-fundamentals-and-applications
#10
Dongshi Zhang, Bilal Gökce, Stephan Barcikowski
Driven by functionality and purity demand for applications of inorganic nanoparticle colloids in optics, biology, and energy, their surface chemistry has become a topic of intensive research interest. Consequently, ligand-free colloids are ideal reference materials for evaluating the effects of surface adsorbates from the initial state for application-oriented nanointegration purposes. After two decades of development, laser synthesis and processing of colloids (LSPC) has emerged as a convenient and scalable technique for the synthesis of ligand-free nanomaterials in sealed environments...
February 13, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28187472/-epi-bowman-keratectomy-clinical-evaluation-of-a-new-method-of-surface-ablation
#11
S Taneri, S Kießler, A Rost, T Schultz, M Elling, B Dick
Purpose A new device for epithelial abrasion before excimer laser surface ablation or corneal cross-linking (CXL) has recently been introduced (Epi-Clear™, Orca Surgical, Kiryat-Shmona, Israel). We have reviewed the literature on the clinical results, potential benefits and drawbacks of this instrument, compared to other methods of epithelial removal. Method Literature search for "Epi-Bowman Keratectomy", "Epi-clear", and "Epikeratome" yielded 1 peer-review publication, 1 non-peer-review publication, 18 posters and presentations at international conferences (European Society of Cataract and Refractive Surgeons [ESCRS] and American Society of Cataract and Refractive Surgery [ASCRS]) on the use of the Epi-Clear™ device before surface ablation, 2 posters on the use of Epi-Clear before corneal crosslinking and 1 presentation on the experimental use of Epi-Clear for removal of a pterygium...
February 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28186767/size-control-of-silver-core-silica-shell-nanoparticles-fabricated-by-laser-ablation-assisted-chemical-reduction
#12
Victor A Ermakov, Ernesto Jiménez-Villar, José Maria Clemente da Silva Filho, Emre Yassitepe, Naga Vishnu Vardhan Mogili, Fernando Iikawa, Gilberto Fernandes De Sá, Carlos Lenz Cesar, Francisco C Marques
Aqueous colloidal silver nanoparticles have a substantial potential in biological application as markers and antibacterial agents, and in surface-enhanced Raman spectroscopy (SERS) applications. A simple method of fabrication and encapsulation into an inert shell is of great importance today in order to make their use ubiquitous. Here we show that colloids of Silver-Core/Silica-Shell nanoparticles can be easily fabricated by a laser ablation assisted chemical reduction method and their sizes can be tuned in the range of 2...
February 10, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28186470/image-guidance-based-on-mri-for-spinal-interstitial-laser-thermotherapy-technical-aspects-and-accuracy
#13
Claudio E Tatsui, Clarissa N G Nascimento, Dima Suki, Behrang Amini, Jing Li, Amol J Ghia, Jonathan G Thomas, R Jason Stafford, Laurence D Rhines, Juan P Cata, Ashok J Kumar, Ganesh Rao
OBJECTIVE Image guidance for spinal procedures is based on 3D-fluoroscopy or CT, which provide poor visualization of soft tissues, including the spinal cord. To overcome this limitation, the authors developed a method to register intraoperative MRI (iMRI) of the spine into a neuronavigation system, allowing excellent visualization of the spinal cord. This novel technique improved the accuracy in the deployment of laser interstitial thermal therapy probes for the treatment of metastatic spinal cord compression...
February 10, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28176952/needle-track-seeding-after-radiofrequency-ablation-for-hepatocellular-carcinoma-prevalence-impact-and-management-challenge
#14
REVIEW
Giampiero Francica
Neoplastic seeding may arise after radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). A low risk of seeding after RFA (0-1.1%) has been reported, which may rise up to 2.5% if ablation followed diagnostic biopsy. Needle track seeding presents with one or multiple rounded nodules along the needle track located within the peritoneum, along the abdominal muscles, which were penetrated by the needle, pleural surface, or in the subcutaneous and cutaneous tissues. The most widely used method for the assessment of seeding nodules is ultrasound (US), which usually displays hypoechoic nodules with intralesional vascularization...
2017: Journal of Hepatocellular Carcinoma
https://www.readbyqxmd.com/read/28169834/development-of-biomimetic-micro-patterned-device-incorporated-with-neurotrophic-gradient-and-supportive-schwann-cells-for-the-applications-in-neural-tissue-engineering
#15
Chia-Wei Yeh, Li-Wen Wang, Hsi-Chin Wu, Yi-Kong Hsieh, Jane Wang, Ming-Hong Chen, Tzu-Wei Wang
In these years, the artificial nerve guidance conduit has been developed as an alternative way to repair peripheral nerve injury. Unlike autologous nerve graft, the artificial nerve guidance conduit without proper stimulating factors and guidance cues still cannot obtain satisfactory prognosis for clinical patients. In this study, a biodegradable polymer-based implantable device has been developed and characterized. By incorporating three stimulating factors: 1) micro-patterned surface that can directionally guide the axon as physical cue; 2) neurotrophic gradient membrane that can continually attract axon outgrowth from the proximal to distal stump as chemical cue; 3) Schwann cells that can support the growth of neurite and form myelin sheath around axon as biological cue, we expect that this construct can be used as a promising nerve guidance conduit for peripheral nerve regeneration...
February 7, 2017: Biofabrication
https://www.readbyqxmd.com/read/28168327/surfactant-protein-d-delays-fas-and-trail-mediated-extrinsic-pathway-of-apoptosis-in-t-cells
#16
Pascal Djiadeu, Lakshmi P Kotra, Neil Sweezey, Nades Palaniyar
Only a few extracellular soluble proteins are known to modulate apoptosis. We considered that surfactant-associated protein D (SP-D), an innate immune collectin present on many mucosal surfaces, could regulate apoptosis. Although SP-D is known to be important for immune cell homeostasis, whether SP-D affects apoptosis is unknown. In this study we aimed to determine the effects of SP-D on Jurkat T cells and human T cells dying by apoptosis. Here we show that SP-D binds to Jurkat T cells and delays the progression of Fas (CD95)-Fas ligand and TRAIL-TRAIL receptor induced, but not TNF-TNF receptor-mediated apoptosis...
February 6, 2017: Apoptosis: An International Journal on Programmed Cell Death
https://www.readbyqxmd.com/read/28166448/treatment-of-gingival-melanin-hyperpigmentation-with-er-cr-ysgg-laser-short-term-follow-up-of-patient
#17
Basak Kusakcİ Seker
The increasing melanin hyperpigmentation of dark skinned individuals was related to the high activity of melanocytes. Also smoking reactive the melanocytes to produce melanin. Gingival depigmentation is a periodontal plastic procedure which has been carried out by various techniques. A healthy 36-years-old female patient complained about unaesthetic gingiva and she had smoked over 17 years. Hyperpigmentation of gingiva observed on the labial surface of both maxilla and mandibula. Er,Cr:YSGG laser was used for depigmentation with wavelength of 2780nm, frequency of 20hz, and pulse energy between 0-300 Mj...
February 6, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28164418/colloidal-metal-nanoparticles-prepared-by-laser-ablation-and-their-applications
#18
Jianming Zhang, Jerome Claverie, Mohamed Chaker, Dongling Ma
This review article highlights the recent advances of the synthesis and application of metal nanoparticles (NPs) fabricated via pulsed laser ablation in liquid (PLAL) phase and also introduces relevant NP formation mechanisms. Although wet-chemical approaches have been well established to synthesize colloidal metal NPs with various components and structures, some inherent drawbacks, such as reaction residuals and / or contaminations, largely limit some of their applications. PLAL method has recently been developed as an alternative approach and received increasing attention for colloidal NP preparation, without involving complicated chemical reactions...
February 5, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28163355/an-enhanced-temperature-index-model-for-debris-covered-glaciers-accounting-for-thickness-effect
#19
M Carenzo, F Pellicciotti, J Mabillard, T Reid, B W Brock
Debris-covered glaciers are increasingly studied because it is assumed that debris cover extent and thickness could increase in a warming climate, with more regular rockfalls from the surrounding slopes and more englacial melt-out material. Debris energy-balance models have been developed to account for the melt rate enhancement/reduction due to a thin/thick debris layer, respectively. However, such models require a large amount of input data that are not often available, especially in remote mountain areas such as the Himalaya, and can be difficult to extrapolate...
August 2016: Advances in Water Resources
https://www.readbyqxmd.com/read/28158076/glass-processing-with-pulsed-co-sub-2-sub-laser-radiation
#20
Christian Weingarten, Emrah Uluz, Andreas Schmickler, Karsten Braun, Edgar Willenborg, André Temmler, Sebastian Heidrich
Recent results of processing fused silica using a high-power Q-switched CO<sub>2</sub> laser source with a maximum output power of 200 W are presented. Compared to the processing with continuous wave laser radiation, the main advantage of pulsed laser radiation is the influence of the light-matter interaction with high laser peak power at small average laser power. An application for the approach presented in this paper is the flexible manufacturing and form correction of optics. This laser-based process is nearly independent of the surface geometry and can even be enhanced by laser polishing and expanded to other glass materials...
February 1, 2017: Applied Optics
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