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https://www.readbyqxmd.com/read/28544902/extraction-and-applications-of-cyanotoxins-and-other-cyanobacterial-secondary-metabolites
#1
REVIEW
Fatima Haque, Sara Banayan, Josephine Yee, Yi Wai Chiang
The rapid proliferation of cyanobacteria in bodies of water has caused cyanobacterial blooms, which have become an increasing cause of concern, largely due to the presence of toxic secondary metabolites (or cyanotoxins). Cyanotoxins are the toxins produced by cyanobacteria that may be harmful to surrounding wildlife. They include hepatotoxins, neurotoxins and dermatotoxins, and are classified based on the organs they affect. There are also non-toxic secondary metabolites that include chelators and UV-absorbing compounds...
May 18, 2017: Chemosphere
https://www.readbyqxmd.com/read/28534286/development-of-a-novel-resin-based-dental-material-with-dual-biocidal-modes-and-sustained-release-of-ag-ions-based-on-photocurable-core-shell-agbr-cationic-polymer-nanocomposites
#2
Weiwei Cao, Yu Zhang, Xi Wang, Yinyan Chen, Qiang Li, Xiaodong Xing, Yuhong Xiao, Xuefeng Peng, Zhiwen Ye
Research on the incorporation of cutting-edge nano-antibacterial agent for designing dental materials with potent and long-lasting antibacterial property is demanding and provoking work. In this study, a novel resin-based dental material containing photocurable core-shell AgBr/cationic polymer nanocomposite (AgBr/BHPVP) was designed and developed. The shell of polymerizable cationic polymer not only provided non-releasing antibacterial capability for dental resins, but also had the potential to polymerize with other methacrylate monomers and prevented nanoparticles from aggregating in the resin matrix...
July 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28531875/elaboration-of-antibacterial-plastic-surfaces-by-a-combination-of-antiadhesive-and-biocidal-coatings-of-natural-products
#3
Jean-Baptiste Paris, Damien Seyer, Thierry Jouenne, Pascal Thébault
Antibacterial polyolefins surfaces, combining biocidal and antiadhesive properties, were elaborated by a covalent grafting of antimicrobial peptides (AMPs), able to kill adherent bacteria, on a pre-immobilized hyaluronic acid (HA) layer, able to repel the micro-organisms. Different HA activation rate for its immobilization, were used to change HA layer morphology and number of residual free carboxylic acid functions for AMPs grafting. Based on adhesion tests on Staphylococcus epidermidis and microscopy fluorescent observations, the presence of the two combined properties was shown to be depended on the HA activation rate...
May 13, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28528649/metal-resistance-and-its-association-with-antibiotic-resistance
#4
Chandan Pal, Karishma Asiani, Sankalp Arya, Christopher Rensing, Dov J Stekel, D G Joakim Larsson, Jon L Hobman
Antibiotic resistance is recognised as a major global threat to public health by the World Health Organization. Currently, several hundred thousand deaths yearly can be attributed to infections with antibiotic-resistant bacteria. The major driver for the development of antibiotic resistance is considered to be the use, misuse and overuse of antibiotics in humans and animals. Nonantibiotic compounds, such as antibacterial biocides and metals, may also contribute to the promotion of antibiotic resistance through co-selection...
2017: Advances in Microbial Physiology
https://www.readbyqxmd.com/read/28528410/comparison-of-toxicities-of-metal-pyrithiones-including-their-degradation-compounds-and-organotin-antifouling-biocides-to-the-japanese-killifish-oryzias-latipes
#5
Madoka Ohji, Hiroya Harino
Japanese killifish Oryzias latipes were exposed to three levels (0, 1, and 10 µg l(-1)) of copper pyrithione (CuPT2), zinc pyrithione (ZnPT2), six of their degradation products, and the organotin compounds tributyltin (TBT) and triphenyltin (TPT) for 48 h at 20 °C. All individual fish exposed to 1 and 10 µg l(-1) of CuPT2 or 10 µg l(-1) of ZnPT2 were dead within 12 h, respectively, and at 24 h the survival rate of the fish exposed to 1 µg l(-1) of ZnPT2 was 50%. All fish exposed to 10 µg l(-1) of ZnPT2 showed morphological abnormalities in the form of vertebral deformity...
May 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28514144/water-purification-using-functionalized-cellulosic-fibers-with-non-leaching-bacteria-adsorbing-properties
#6
Anna Elizabeth Ottenhall, Josefin Illergård, Monica Kerstin Ek
Portable purification systems are easy ways to obtain clean drinking water when there is no large-scale water treatment available. In this study, the potential to purify water using bacteria adsorbing cellulosic fibers, functionalized with polyelectrolytes according to the Layer-by-Layer method, is investigated. The adsorbed polyelectrolytes create a positive charge on the fiber surface that physically attracts and bonds with bacteria. Three types of cellulosic materials have been modified and tested for the bacterial removal capacity in water...
May 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28512449/antibacterial-potential-of-an-antimicrobial-agent-inspired-by-peroxidase-catalyzed-systems
#7
Lilit Tonoyan, Gerard T A Fleming, Paul H Mc Cay, Ruairi Friel, Vincent O'Flaherty
Antibiotic resistance is an increasingly serious threat to global health. Consequently, the development of non-antibiotic based therapies and disinfectants, which avoid induction of resistance, or cross-resistance, is of high priority. We report the synthesis of a biocidal complex, which is produced by the reaction between ionic oxidizable salts-iodide and thiocyanate-in the presence of hydrogen peroxide as an oxidation source. The reaction generates bactericidal reactive oxygen and iodine species. In this study, we report that the iodo-thiocyanate complex (ITC) is an effective bactericidal agent with activity against planktonic and biofilm cells of Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus and methicillin-resistant S...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28505510/a-potential-mechanism-for-degradation-of-4-5-dichloro-2-n-octyl-3-2h-isothiazolone-dcoit-by-brown-rot-fungus-gloeophyllum-trabeum
#8
Yuan Zhu, Jing Xue, Jinzhen Cao, Hongzhan Xiao
This study aims to investigate the biodegradation of 4,5-dichloro-2-(n-octyl)-3[2H]-isothiazolone (DCOIT) by a brown-rot fungus Gloeophyllum trabeum as well as the involved mechanism. In the present study, the retentions of DCOIT in treated Masson pine (Pinus massoniana) (MP) chips were determined periodically after incubation with G. trabeum. Then a Fenton-like reaction, known as the chelator-mediated Fenton (CMF) chemistry was used to degrade DCOIT that mimics the degradation pathway of DCOIT by typical brown-rot fungi, and the degradation intermediates were further analyzed...
May 1, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28499739/diatom-communities-on-commercial-biocidal-fouling-control-coatings-after-one-year-of-immersion-in-the-marine-environment
#9
Thirumahal Muthukrishnan, Sergey Dobretsov, Mario De Stefano, Raeid M M Abed, Barry Kidd, Alistair A Finnie
Little is known about the effect of commercial biocidal fouling control coatings on fouling diatom communities and their growth forms after long periods of exposure in the marine tropical environment. The current study investigated the abundance and composition of fouling diatom communities developed on 11 commercially available biocidal antifouling coatings, covering the three main technology types in recent historic use (Self-Polishing Copolymers, Self-Polishing Hybrid and Controlled Depletion Polymers) after one year of static immersion at two locations in Muscat, Oman (Marina Shangri La and Marina Bandar Rowdha)...
May 4, 2017: Marine Environmental Research
https://www.readbyqxmd.com/read/28499642/efficiency-of-four-currently-used-decontamination-conditionings-in-romania-against-aspergillus-and-candida-strains
#10
D Lorin, R T Cristina, V Teusdea, E Mitrănescu, F Muselin, M Butnariu, G David, E Dumitrescu
INTRODUCTION: Efficacy of four commercial biocidal products (noted A to D), using manufacturers' recommendations, and a contact time of 30minutes, were evaluated in the purpose of standard SR EN1657: 2006 adapted. METHODS: Were used four strains, two as reference: Aspergillus brasiliensis (niger) (ATCC 16404) and Candida albicans (ATCC 10231), and two isolates: Aspergillus flavus and respectively Aspergillus fumigatus. The inoculum plates containing Malt Extract Agar (MEA) were incubated 48h for C...
May 9, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28495626/promising-biocidal-activity-of-thymol-loaded-chitosan-silver-nanoparticles-t-c-agnps-as-anti-infective-agents-against-perilous-pathogens
#11
H M Manukumar, S Umesha, H N Naveen Kumar
The advent of biodegradable polymer-encapsulated drug nanoparticles has made an exciting area of drug delivery research. The present study investigated novel and simple route for synthesis of thymol loaded chitosan silver nanoparticles (T-C@AgNPs) using chitosan and thymol as reducing, capping agent respectively to understand the therapeutic efficacy. The UV-vis spectroscopy, DLS, FT-IR, SEM, EDS, XRD used for characterization and radical scavenging activity, anti-microbial and biocompatibility was taken to ascertain an efficacy of novel T-C@AgNPs...
May 8, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28492331/high-throughput-screening-to-identify-potent-and-specific-inhibitors-of-microbial-sulfate-reduction
#12
Hans K Carlson, Mark R Mullan, Lorraine A Mosqueda, Steven Chen, Michelle R Arkin, John D Coates
The selective perturbation of complex microbial ecosystems to predictably influence outcomes in engineered and industrial environments remains a grand challenge for geomicrobiology. In some industrial ecosystems, such as oil reservoirs, sulfate reducing microorganisms (SRM) produce hydrogen sulfide which is toxic, explosive, and corrosive. Despite the economic cost of sulfidogenesis, there has been minimal exploration of the chemical space of possible inhibitory compounds, and very little work has quantitatively assessed the selectivity of putative souring treatments...
May 26, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28487674/uncovering-potential-applications-of-cyanobacteria-and-algal-metabolites-in-biology-agriculture-and-medicine-current-status-and-future-prospects
#13
REVIEW
Rachana Singh, Parul Parihar, Madhulika Singh, Andrzej Bajguz, Jitendra Kumar, Samiksha Singh, Vijay P Singh, Sheo M Prasad
Cyanobacteria and algae having complex photosynthetic systems can channelize absorbed solar energy into other forms of energy for production of food and metabolites. In addition, they are promising biocatalysts and can be used in the field of "white biotechnology" for enhancing the sustainable production of food, metabolites, and green energy sources such as biodiesel. In this review, an endeavor has been made to uncover the significance of various metabolites like phenolics, phytoene/terpenoids, phytols, sterols, free fatty acids, photoprotective compounds (MAAs, scytonemin, carotenoids, polysaccharides, halogenated compounds, etc...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28481104/effect-of-morphology-and-size-of-halloysite-nanotubes-on-functional-pectin-bionanocomposites-for-food-packaging-applications
#14
Maziyar Makaremi, Pooria Pasbakhsh, Giuseppe Cavallaro, Giuseppe Lazzara, Yoong Kit Aw, Sui Mae Lee, Stefana Milioto
Pectin bionanocomposite films filled with various concentrations of two different types of halloysite nanotubes were prepared and characterized in this study as potential films for food packaging applications. The two types of halloysite nanotubes were long and thin (patch) (200-30 000 nm length) and short and stubby (Matauri Bay) (50-3000 nm length) with different morphological, physical, and dispersibility properties. Both matrix (pectin) and reinforcer (halloysite nanotubes) used in this study are considered as biocompatible, natural, and low-cost materials...
May 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28476978/study-of-bio-fabrication-of-iron-nanoparticles-and-their-fungicidal-property-against-phytopathogens-of-apple-orchards
#15
Hilal Ahmad, Kalyanaraman Rajagopal, Ashiq Hussain Shah, Arif Hussain Bhat, Kalyanaraman Venugopal
Current research trends on iron nanoparticles (FeNPs) are extensively focused because of their unique magnetic and electrical properties mostly applicable in essential medical devices. However, their fungicidal property against plant pathogens is very less known until date. Present study demonstrates a green technique for blending of FeNPs by utilising aqueous extract of neem leaf (Azadirachta indica A. Juss.) as reducing agent. Various characterisation techniques such as ultraviolet (UV)-visible spectroscopy, Fourier transform infrared spectroscopy transmission electron microscopy, scanning electron microscopy and X-ray diffraction were performed for FeNPs...
April 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28475985/long-alkyl-chain-imidazolium-ionic-liquids-antibiofilm-activity-against-phototrophic-biofilms
#16
G Kiran Kumar Reddy, Y V Nancharaiah, V P Venugopalan
Biofilm formation is problematic and hence undesirable in medical and industrial settings. In addition to bacteria, phototrophic organisms are an integral component of biofilms that develop on surfaces immersed in natural waters. 1-Alkyl-3-methyl imidazolium ionic liquids (IL) with varying alkyl chain length were evaluated for their influence on the formation of monospecies (Navicula sp.) and multispecies biofilms under phototrophic conditions. An IL with a long alkyl side chain, 1-hexadecyl-3-methylimidaazolium chloride ([C16(MIM)][Cl]) retarded growth, adhesion and biofilm formation of Navicula sp...
April 23, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28475713/tcdd-influences-reservoir-of-antibiotic-resistance-genes-in-murine-gut-microbiome
#17
Robert D Stedtfeld, Tiffany M Stedtfeld, Kelly A Fader, Maggie R Williams, Prianca Bhaduri, John Quensen, Timothy R Zacharewski, James M Tiedje, Syed A Hashsham
Dysbiosis of the gut microbiome via antibiotics, changes in diet, and infection can select for bacterial groups that more frequently harbor antimicrobial resistance genes (ARGs) and mobile genetic elements (MGEs). However, the impact of environmental toxicants on the reservoir of ARGs in the gut microbiome has received less attention. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a potent aryl hydrocarbon receptor (AhR) agonist with multiple toxic health effects including immune dysfunction. The selective pressure of TCDD on the abundance of ARG and MGE harboring gut populations was examined using C57BL/6 mice exposed to 0-30 μg/kg TCDD for 28 and 92 days with the latter having a 30-day recovery period...
May 4, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/28470404/ex-vivo-human-skin-permeation-of-methylchloroisothiazolinone-mci-and-methylisothiazolinone-mi
#18
Aurélie Berthet, Philipp Spring, David Vernez, Gregory Plateel, Nancy B Hopf
Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are biocides used in many types of products such as cosmetics, paints, and cleaning agents. Skin contact is often encountered when using these products. Although MCI and MI are strong allergens and cause skin irritation, no scientific skin permeation study has been reported except for some unpublished data. Therefore, this study assessed the permeation of MCI and MI both separately and as a mixture through freshly dermatomed human skin (800 µm) in a flow-through diffusion cell system...
May 3, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28463667/culture-independent-detection-of-chlorhexidine-resistance-genes-qaca-b-and-smr-in-bacterial-dna-recovered-from-body-sites-treated-with-chlorhexidine-containing-dressings
#19
Md Abu Choudhury, Hanna E Sidjabat, Irani U Rathnayake, Nicole Gavin, Raymond J Chan, Nicole Marsh, Shahera Banu, Flavia Huygens, David L Paterson, Claire M Rickard, David J McMillan
PURPOSE: Dressings containing chlorhexidine gluconate (CHG) are increasingly used in clinical environments for prevention of infection at central venous catheter insertion sites. Increased tolerance to this biocide in staphylococci is primarily associated with the presence of qacA/B and smr genes. METHODOLOGY: We used a culture-independent method to assess the prevalence of these genes in 78 DNA specimens recovered from the skin of 43 patients at catheter insertion sites in the arm that were covered with CHG dressings...
April 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28462746/disinfectant-susceptibility-profiling-of-glutaraldehyde-resistant-nontuberculous-mycobacteria
#20
Winona Burgess, Alyssa Margolis, Sara Gibbs, Rafael Silva Duarte, Mary Jackson
OBJECTIVE Activated alkaline glutaraldehyde (GTA) remains one of the most widely used high-level disinfectants worldwide. However, several reports have highlighted the potential for nontuberculous mycobacteria to develop high-level resistance to this product. Because aldehyde resistance may lead to cross-resistance to other biocides, we investigated the susceptibility profile of GTA-resistant Mycobacterium chelonae and M. abscessus isolates to various disinfectant chemistries. METHODS High-level disinfectants commonly used in the reprocessing of endoscopes and other heat-sensitive, semicritical medical equipment, including different formulations of aldehyde-based products and oxidizing agents, were tested against 10 slow- and fast-growing, GTA-susceptible and GTA-resistant, Mycobacterium isolates in suspension tests and carrier tests at different temperatures...
May 2, 2017: Infection Control and Hospital Epidemiology
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