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Ting Wei, Wenjun Zhan, Qian Yu, Hong Chen
Smart biointerfaces with capability to regulate cell-surface interactions in response to external stimuli are of great interest for both fundamental research and practical applications. Smart surfaces with "ON/OFF" switchability for a single function such as cell attachment/detachment are well-known and useful, but the ability to switch between two different functions may be seen as the next level of "smart". In this work reported, a smart supramolecular surface capable of switching functions reversibly between bactericidal activity and bacteria-releasing ability in response to UV-visible light is developed...
July 20, 2017: ACS Applied Materials & Interfaces
JoAnn S Roberts, Kalina R Atanasova, Jungnam Lee, Gill Diamond, Jeff Deguzman, Chul Hee Choi, Özlem Yilmaz
Porphyromonas gingivalis, a major opportunistic pathogen in the etiology of chronic periodontitis, successfully survives in human gingival epithelial cells (GECs). P. gingivalis abrogates the effects of a host danger molecule, extracellular ATP (eATP)/P2X7 signaling, such as the generation of reactive oxygen species (ROS) via the mitochondria and NADPH oxidases (NOX) from primary GECs. However, antimicrobial functions of ROS production are thoroughly investigated in myeloid-lineage immune cells and have not been well-understood in epithelial cells...
2017: Frontiers in Cellular and Infection Microbiology
Misha Y Vaidya, Andrew J McBain, Jonathan A Butler, Craig E Banks, Kathryn A Whitehead
The effects of metal ion solutions (silver, copper, platinum, gold and palladium) were determined individually and in combination against Enterococcus faecium, Acinetobacter baumannii and Klebsiella pneumoniae. Platinum, gold and palladium showed the greatest antimicrobial efficacy in zone of inhibition (ZoI) assays. When tested in combinations using ZoI assays, gold/platinum, gold/palladium and platinum/palladium were indicative of synergy. Microbial inhibitory concentration demonstrated platinum and gold against Enterococcus faecium, platinum against Klebsiella pneumoniae and platinum and silver against Acinetobacter baumannii were optimal...
July 19, 2017: Scientific Reports
Fardin Ahmadi, Chris Sparham, Janusz Pawliszyn
In this paper problems associated with preparation of aqueous standard of highly hydrophobic compounds such as partial precipitation, being lost on the surfaces, low solubility in water and limited sample volume for accurate determination of their distribution coefficients are addressed. The following work presents two approaches that utilize blade thin film microextraction (TFME) to investigate partitioning of UV filters and biocides to humic acid (dissolved organic carbon) and sediment. A steady-state concentration of target analytes in water was generated using a flow-through aqueous standard generation (ASG) system...
July 14, 2017: Environmental Pollution
Tanya M Brown, Hideshige Takada
The complex nature of ocean pollution underscores the utility in identifying and characterizing a limited number of "indicators" that enables scientists and managers to track trends over space and time. This paper introduces a special issue on indicators of marine pollution in the North Pacific Ocean and builds on a scientific session that was held at the North Pacific Marine Science Organization. The special issue highlights studies using a variety of indicators to provide insight into the identification of legacy and emerging contaminants, the ranking of priority pollutants from various sources, and the effects of contaminants on ecosystem health in the North Pacific Ocean...
July 14, 2017: Archives of Environmental Contamination and Toxicology
Divya Goyal, Gaganpreet Kaur, Rupinder Tewari, Rajesh Kumar
The effect of silver nanoparticle anisotropy on the antibacterial properties has been studied against Escherichia coli, Staphylococcus aureus, Bacillus, Vibrio cholerae, and Streptococcus pyogenes. Anisotropic silver nanoparticles have been synthesized by solvothermal process. The UV-visible absorption, X-ray diffraction, and TEM studies show the anisotropic nature of silver nanoparticles. The results demonstrate that the anisotropic silver nanoparticles undergo a shape-dependent interaction with the bacteria, and the nanoparticles with higher anisotropy exhibit the superior antibacterial activity...
July 13, 2017: Environmental Science and Pollution Research International
Antonio Speciale, Domenico Trombetta, Antonella Saija, Antonio Panebianco, Filippo Giarratana, Graziella Ziino, Paola Lucia Minciullo, Francesco Cimino, Sebastiano Gangemi
Anisakis spp. is a parasitic nematode whose infective third-stage larvae may be found within the flesh of fish species commonly consumed by humans. Thorough cooking or freezing should render the fish safe for consumption; furthermore, marinating solutions containing biocidal agents might have a significant action against Anisakis larvae. Some studies suggest a relationship between some parasitic infections and development of inflammatory bowel disorders, and Anisakis infection might be a risk factor for stomach or colon cancer...
July 12, 2017: Parasitology Research
Piersandro Pallavicini, Barbara Bassi, Giuseppe Chirico, Maddalena Collini, Giacomo Dacarro, Emiliano Fratini, Pietro Grisoli, Maddalena Patrini, Laura Sironi, Angelo Taglietti, Marcel Moritz, Ioritz Sorzabal-Bellido, Arturo Susarrey-Arce, Edward Latter, Alison J Beckett, Ian A Prior, Rasmita Raval, Yuri A Diaz Fernandez
Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms...
July 12, 2017: Scientific Reports
Bożena Futoma-Kołoch, Bartłomiej Dudek, Katarzyna Kapczyńska, Eva Krzyżewska, Martyna Wańczyk, Kamila Korzekwa, Jacek Rybka, Elżbieta Klausa, Gabriela Bugla-Płoskońska
A new emerging phenomenon is the association between the incorrect use of biocides in the process of disinfection in farms and the emergence of cross-resistance in Salmonella populations. Adaptation of the microorganisms to the sub-inhibitory concentrations of the disinfectants is not clear, but may result in an increase of sensitivity or resistance to antibiotics, depending on the biocide used and the challenged Salmonella serovar. Exposure of five Salmonella enterica subsp. enterica serovar Senftenberg (S...
July 11, 2017: International Journal of Molecular Sciences
Fernando Poyatos, Fátima Morales, A W Nicholson, Antonio Giordano
The study of the physiological action of microorganisms in artistic materials is one of the most interesting topics in biodeterioration nowadays. Pathologies and illnesses of organic and inorganic materials provoked by microorganisms can be treated by experts by a variety of preventive interventions. Artistic medicine encompasses the monitoring of the exhibition and storage of art, as well as proper environmental conditions and the regular cleaning of museums. Biodeterioration control is essential in order to prevent fungal and bacterial contamination in artwork...
July 8, 2017: Journal of Cellular Physiology
Ramanathan Srinivasan, Sivasubramanian Santhakumari, Arumugam Veera Ravi
Vibrio harveyi is a potent biofilm former, which confers resistance to multiple antimicrobials, disinfectants, chemicals and biocides. The prevalence of biofilm mediated antibiotic resistance among aquatic bacterial pathogens stresses the search for novel alternative approach to treat vibriosis in aquaculture. Exploring suitable therapeutics from natural resources could be a novel area of research. Therefore, this work was executed to evaluate the inhibitory effect of Piper betle ethyl acetate extract (PBE) on bioluminescence production and biofilm formation of V...
July 4, 2017: Microbial Pathogenesis
Pooja Chavan, Rajesh Kumar, Hiren Joshi, Ramalingam Kirubagaran, Vayalam P Venugopalan
Toxic effects of continuous low dose application of the antifouling biocide chlorine on marine benthic organisms were monitored using transplanted green mussels (Perna viridis) and a suite of biomarkers. Caged mussels were deployed in chlorinated and non-chlorinated sections of the cooling system of an operating electric power plant. Biomarkers indicative of general stress, oxidative stress (superoxide dismutase and catalase), and DNA integrity, along with expression of stress proteins, were studied to assess the effects...
July 7, 2017: Environmental Science and Pollution Research International
Laura Narciso, Tiziana Catone, Gabriele Aquilina, Leonello Attias, Isabella De Angelis, Maria Grazia Iuliano, Roberta Tassinari, Alberto Mantovani, Francesca Maranghi
Children show unique features concerning chemical hazards and risks, due to different exposure scenarios, age-related metabolic capacity and biological susceptibility linked to post-natal development. Chemical Regulatory frameworks state the need of children risk characterization. Current testing guidelines covering post-natal development are not routinely required by regulatory applications other than pesticides and biocides. Juvenile toxicity studies are foreseen for paediatric drugs: the toxicological repeated-dose tests don't allow accurate evaluations of effects upon direct exposure of immature organism...
July 3, 2017: Reproductive Toxicology
Severyn Salis, Cecilia Testa, Paola Roncada, Sara Armorini, Nicola Rubattu, Angelo Ferrari, Roberto Miniero, Gianfranco Brambilla
The occurrence of pesticides intended for non-agricultural use was investigated in 206 dust samples drawn from vacuum-cleaner bags from residential flats in Italy. The multi-residue analysis targeted on 95 different active principles was performed with UPLC-MS/MS, with a Limit of Quantification (LOQ) of 0.008 μg/g dry weight. The results indicated the presence of imidacloprid (IMI) and carbendazim (CARB) in 30% and 26% of the samples, with a mean and P95 concentration between 1.6 and 39 and between 0.08 and 4...
July 5, 2017: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
John H Thurston, Necia M Hunter, Lacey J Wayment, Kenneth A Cornell
In this manuscript, we describe the fabrication of photoactive biocidal or sporicidal films from urea-derived graphitic carbon nitride (u-g-C3N4). Co-deposited films of u-g-C3N4 and Escherichia coli O157:H7 (IC50=14.1±0.2mJ) or Staphylococcus aureus (methicillin resistant IC50=33.5±0.2mJ, methicillin sensitive IC50=42.7±0.5mJ) demonstrated significantly enhanced bactericidal behavior upon administration of visible radiation (400nm≤λ≤426nm). In all cases, complete eradication of the microbial sample was realized upon administration of 100mJ of visible radiation, while no antimicrobial activity was observed for non-irradiated samples...
June 27, 2017: Journal of Colloid and Interface Science
Maria Alexandra Bighiu, Elena Gorokhova, Bethanie Carney Almroth, Ann-Kristin Eriksson Wiklund
Harbours with limited water exchange are hotspots of contaminant accumulation. Antifouling paints (AF) contribute to this accumulation by leaching biocides that may affect non-target species. In several leisure boat harbours and reference areas in the Baltic Sea, chronic exposure effects were evaluated using caging experiments with the snail Theodoxus fluviatilis. We analysed variations in ecologically relevant endpoints (mortality, growth and reproduction) in concert with variation in metallothionein-like proteins (MTLP) levels...
2017: PloS One
Magdalena Wypij, Joanna Czarnecka, Hanna Dahm, Mahendra Rai, Patrycja Golinska
In this study, we present the in vitro antifungal activity of silver nanoparticles (AgNPs) synthesized from acidophilic actinobacterium Pilimelia columellifera subsp. pallida SL19 strain, alone and in combination with antibiotics viz., amphotericin B, fluconazole, and ketoconazole against pathogenic fungi, namely Candida albicans, Malassezia furfur, and Trichophyton erinacei. The minimum inhibitory concentration (MIC) and minimum biocidal concentration (MBC) of AgNPs against test fungi were evaluated. The fractional inhibitory concentration (FIC) index was determined to estimate antifungal activity of AgNPs combined with antibiotics...
July 3, 2017: Journal of Basic Microbiology
Shuai Wang, Chang Wang, Lingfei Gao, Hua Cai, Yonghui Zhou, Yanbei Yang, Changgeng Xu, Wenya Ding, Jianqing Chen, Ishfaq Muhammad, Xueying Chen, Xinmiao He, Di Liu, Yanhua Li
Streptococcus suis (S. suis) form biofilms and causes severe diseases in humans and pigs. Biofilms are communities of microbes embedded in a matrix of extracellular polymeric substances. Eradicating biofilms with the use of antibiotics or biocides is often ineffective and needs replacement with other potential agents. Compared to conventional agents, promising and potential alternatives are biofilm-inhibiting compounds without impairing growth. Here, we screened a S. suis adhesion inhibitor, rutin, derived from Syringa...
2017: Frontiers in Pharmacology
Daniela Coelho Dos Santos, Lara Rodrigues Schneider, Andressa da Silva Barboza, Ângela Diniz Campos, Rafael Guerra Lund
ETHNOPHARMACOLOGICAL RELEVANCE: The antimicrobial potential of Tagetes minuta was correlated with its traditional use as antibacterial, insecticidal, biocide, disinfectant, anthelminthic, antifungal, and antiseptic agent as well as its use in urinary tract infections. AIM OF THE STUDY: This study aimed to systematically review articles and patents regarding the antimicrobial activity of T. minuta and give rise to perspectives on this plant as a potential antimicrobial agent...
June 29, 2017: Journal of Ethnopharmacology
X Chen, Y Liu, M Fan, Z Wang, W Wu, J Wang
The effect of thermal treatments and several biocides on the viability of Lactobacillus virulent phage P1 was evaluated. Times to achieve 99% inactivation (T99) of phage at different treatment conditions were calculated. The thermal treatments applied were 63, 72, and 90°C in 3 suspension media (de Man, Rogosa, Sharpe broth, reconstituted skim milk, and Tris magnesium gelatin buffer). Phage P1 was completely inactivated in 5 and 10 min at 90 and 72°C, respectively; however, reconstituted skim milk provided better thermal protection at 63°C...
June 28, 2017: Journal of Dairy Science
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