Paul Lajos, Nahidh Hasaniya, Walter Ehrman, Annees Razzouk
Malignancy of the pericardium is a very rare entity. We describe here a case of a 38-year-old male admitted because of chest pain and shortness of breath. Following magnetic resonance imaging and CT-guided biopsy of the mediastinal mass, spindle cell sarcoma of the pericardium was diagnosed. The tumor was deemed unresectable due to invasion of vital mediastinal structures. The patient then underwent neoadjuvant chemotherapy with three cycles of ifosfamide, doxorubicin, and mesran. This resulted in a noticeable reduction in tumor size confirmed by follow-up magnetic resonance imaging and repeat transesophogeal echo...
March 2004: Journal of Cardiac Surgery