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https://www.readbyqxmd.com/read/29164710/expression-profiles-of-immunity-and-reproductive-genes-during-transition-period-in-holstein-cattle
#1
A I Ateya, M S Hussein, H M Ghanem, R M Saleh, W B El-Domany, Y Y Elseady
The transition period is a critical time for dairy cows as the animal is subjected to the physiological stress accompanying parturition. Immunosuppression and health status were examined during this period in 80 Holstein cows. Blood samples were taken from each cow 3, 2 and 1 week before and after calving, and at calving (0 day). RNA was extracted and subjected to real-time PCR to determine mRNA levels for the immune-related genes TLR 2, 4, 6, 7 and β-defensin 5 in addition to the reproduction-related genes prolactin and IGF-I...
November 21, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/29016575/role-of-intravenous-ferric-carboxy-maltose-in-pregnant-women-with-iron-deficiency-anaemia
#2
Vineet Mishra, Khusaili Gandhi, Priyankur Roy, Shaheen Hokabaj, Kunur N Shah
BACKGROUND: Iron deficiency is a common nutritional deficiency amongst women of childbearing age. Peri-partum iron deficiency anaemia is associated with significant maternal, foetal and infant morbidity. Current options for treatment include oral iron, which can be ineffective and poorly tolerated, and red blood cell transfusions, which carry an inherent risk and should be avoided. Ferric carboxymaltose is a modern treatment option. The study was designed to assess the safety and efficacy of intravenous ferric carboxymaltose for correction of iron deficiency anaemia in pregnant women...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28868316/a-rare-and-late-complication-after-left-ventricular-assist-device-explantation
#3
George Gradinariu, André R Simon, Jullien Gaer
Late complications can arise after explantation of a left ventricular assist device. We report the case of a patient who presented at the age of 19 years with peri-partum cardiomyopathy and was initially managed with a biventricular support device, which was subsequently upgraded to an ambulatory left ventricular assist device. This was successfully explanted after myocardial recovery via a minimally invasive approach 7 months later. The patient re-presented 5 years following explantation with hemoptysis. At redo sternotomy, a 10-cm remnant of the outflow graft was found to be eroding the surface of the right lung...
April 2017: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/28779903/peripartum-cardiomyopathy-is-associated-with-increased-uric-acid-concentrations-a-population-based-study
#4
MULTICENTER STUDY
Iftach Sagy, Amjad Abu Salman, Louise Kezerle, Offer Erez, Idan Yoel, Leonid Barski
BACKGROUND: Peri-partum cardiomyopathy (PPCM) is a clinical heart failure that usually develops during the final stage of pregnancy or the first months following delivery. High maternal serum uric acid concentrations have been previous associated with heart failure and preeclampsia. OBJECTIVES: 1) To explored the clinical characteristics of PPCM patients; and 2) to determine the association between maternal serum uric acid concentrations and PPCM. METHODS: This is a retrospective population based case control study...
September 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28708496/comparative-evaluation-of-haematological-parameters-and-erythrocyte-membrane-stability-in-pregnant-and-lactating-goats-in-different-seasons-of-tropical-savannah
#5
B Habibu, H J Makun, L S Yaqub, H U Buhari, T Aluwong, M U Kawu
Haematological parameters and erythrocyte osmotic fragility (EOF) are commonly used as indicators of health status and erythrocyte membrane integrity. Variations in haematological parameters and EOF in late gestation and early lactation during the cold-dry (CDS), hot-dry (HDS) and rainy (RAS) seasons were studied in sixty (n = 60) Red Sokoto goats (20 goats for each season). The ambient temperatures and temperature-humidity index recorded were higher in the afternoon hours of the HDS and RAS, but lower in the morning hours of the CDS as compared with the thermoneutral zone of goats...
September 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28515515/the-parturient-in-the-interventional-radiology-suite-new-frontier-in-obstetric-anaesthesia
#6
REVIEW
Tasneem Dhansura, Nabila Shaikh
The anaesthesiologist's presence during interventional radiology (IR) is increasing due to increasingly ill patients and intricate procedures. The management of a parturient in IR suite is complex in terms of logistics of an unfamiliar procedure in an unfamiliar area. The literature available is largely written by radiologists with little attention paid to anaesthetic details and considerations. In the Indian scenario, in the absence of hybrid operating rooms (ORs), logistics involve transport of a parturient back and forth between the IR suite and the OR...
April 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28494909/remifentanil-as-an-alternative-to-epidural-analgesia-for-vaginal-delivery-a-meta-analysis-of-randomized-trials
#7
Myeongjong Lee, Fang Zhu, Jessica Moodie, Zhe Zhang, Davy Cheng, Janet Martin
OBJECTIVES: Although epidural analgesia is considered the gold standard for labor pain management, its use may be restricted in some conditions due to clinical contraindications or availability, and suitable alternatives may be required. The objective of this meta-analysis was to determine whether evidence from randomized trials suggests remifentanil PCA (R-PCA) results in significant differences in maternal satisfaction, analgesic efficacy, and safety compared with conventional epidural analgesia (EA)...
June 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28455085/randomized-controlled-trial-of-intravenous-acetaminophen-for-postcesarean-delivery-pain-control
#8
RANDOMIZED CONTROLLED TRIAL
Brie Altenau, Catrina C Crisp, C Ganga Devaiah, Donna S Lambers
BACKGROUND: Cesarean delivery is a common surgery in the United States, with 1.3 million performed during 2009.(1) Obstetricians must balance the growing concern with opioid abuse, dependence, and side effects with optimal postoperative pain control. Intravenous acetaminophen may represent an additional method to decrease the reliance on opioid medications and improve postoperative pain following cesarean delivery. OBJECTIVE: The objective of the study was to determine whether the administration of intravenous acetaminophen following routine scheduled cesarean delivery would decrease the need for narcotic medications to control postoperative pain...
September 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28364833/peripartum-dynamics-of-coxiella-burnetii-infections-in-intensively-managed-dairy-goats-associated-with-a-q-fever-outbreak-in-australia
#9
COMPARATIVE STUDY
Michael Muleme, John Stenos, Gemma Vincent, Colin R Wilks, Joanne M Devlin, Angus Campbell, Alexander Cameron, Mark A Stevenson, Stephen Graves, Simon M Firestone
Coxiella burnetii may cause reproduction disorders in pregnant animals but subclinical infection in other animals. Unrecognised disease may delay implementation of control interventions, resulting in transmission of infection to other livestock and to humans. Seroreactivity to C. burnetii phase-specific antigens, is routinely used to interpret the course of human Q fever. This approach could be similarly useful in identifying new and existing infections in livestock herds to help describe risk factors or production losses associated with the infections and the implementation of disease-control interventions...
April 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28176472/suspected-atypical-haemolytic-uraemic-syndrome-in-two-post-partum-patients-with-foetal-death-in-utero-responding-to-eculizumab
#10
REVIEW
Justin Chua, Kathy Paizis, Simon Z He, Peter Mount
BACKGROUND: Atypical haemolytic uraemic syndrome (aHUS) is a rare condition with the triad of microangiopathic haemolytic anaemia, thrombocytopenia and acute kidney injury. Other conditions that present in a similar manner peri-partum include thrombotic thrombocytopaenic purpura, and pregnancy associated conditions including HELLP syndrome (haemolysis, elevated liver enzymes and low platelets), severe pre-eclampsia and less commonly acute fatty liver of pregnancy. CASE REPORTS: We describe two cases of suspected aHUS, who presented post-partum with foetal death-in-utero at 33 and 37 weeks respectively...
February 2017: Nephrology
https://www.readbyqxmd.com/read/28173771/a-survey-of-healthcare-providers-knowledge-and-attitudes-regarding-pain-relief-in-labor-for-women-in-ethiopia
#11
Mary McCauley, Catriona Stewart, Birhanu Kebede
BACKGROUND: To explore healthcare providers' knowledge and attitudes to the need for pain relief for women in labor. METHODS: A structured questionnaire (n = 200) distributed to healthcare providers working in the obstetric departments, including theatres, of three public hospitals in different settings (rural, peri-urban and urban) in Ethiopia. Descriptive analysis was performed using Excel 2013 and SPSS version 22 for associations. RESULTS: The response rate was 81...
February 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27994260/a-case-of-successful-thromboelastographic-guided-resuscitation-after-postpartum-hemorrhage-and-cardiac-arrest
#12
M Hurwich, D Zimmer, E Guerra, E Evans, T Shire, M Abernathy, J T Shreve, G R Kolettis, M T McCurdy, F J Castellino, M Walsh
Amniotic fluid embolism (AFE) is an unusual cause of life threatening peri partum hemorrhage (PPH). AFE resuscitation is often associated with renal and respiratory insufficiency, and a coagulopathy similar to disseminated intravascular coagulation (DIC). Resuscitation requires immediate recognition and limited use of crystalloid. We present a case of PPH caused by AFE with resultant cardiac arrest, renal and respiratory failure, and DIC-like coagulopathy, whose successful resuscitation was guided by perfusionist-directed serial thromboelastography (TEG)...
December 2016: Journal of Extra-corporeal Technology
https://www.readbyqxmd.com/read/27899291/dynamic-changes-in-sleep-pattern-during-post-partum-in-normal-pregnancy-in-rat-model
#13
Neelima Sivadas, Arathi Radhakrishnan, B S Aswathy, Velayudhan Mohan Kumar, Kamalesh K Gulia
To develop an animal model for studies on peri-partum sleep disorders, sleep patterns in female Wistar rats during pregnancy, post-partum and after weaning, were assessed and associated adaptive changes in their anxiety were examined. Adult nulliparous female rats, maintained in standard laboratory conditions with ad libitum food and water, were surgically implanted with electroencephalogram and electromyogram electrodes under anaesthesia for objective assessment of sleep-wakefulness (S-W). After post-surgical recovery, three control recordings of S-W were taken for 24h before the animals were kept for mating...
November 27, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27832586/the-human-microbiome-before-birth
#14
Martin J Blaser, Maria G Dominguez-Bello
The conservation of the microbiota within humans and other hominids suggests an ancient assembly that has been selected to optimize host fitness. Pregnancy induces changes in the maternal microbiome just before the intergenerational hand-off of the microbiota. Interventions, including peri-partum antibiotics and Cesarean sections, may have unintended effects on babies.
November 9, 2016: Cell Host & Microbe
https://www.readbyqxmd.com/read/27651622/quantification-of-peri-partum-blood-loss-training-module-and-clot-conversion-factor
#15
Suvarna Satish Khadilkar, Akanksha Sood, Prajakta Ahire
OBJECTIVES: To design an objective and accurate method to assess the peri-partum blood loss and to document the benefits of using this method on estimation of blood loss by healthcare professionals. MATERIALS AND METHODS: This prospective study was conducted over 6 months at Cama Albless Hospital, Mumbai. To quantify the loss of liquid blood and clots, we made use of plastic drapes, measuring jars, gravimetric method and a training module along with novel clot conversion factor which was designed to validate the visual assessment of blood loss by healthcare professionals...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27518778/the-challenges-of-a-successful-pregnancy-in-a-patient-with-adult-refsum-s-disease-due-to-phytanoyl-coa-hydroxylase-deficiency
#16
Karolina M Stepien, Anthony S Wierzbicki, Bwee T Poll-The, Hans R Waterham, Christian J Hendriksz
We describe the management and outcomes of pregnancy in a 27-year-old woman with infantile-onset Adult Refsum's disease (ARD). She presented in infancy but was diagnosed with ARD at the age of 10 on basis of phytanic acidaemia and later confirmed to have the phytanoyl-CoA hydroxylase ((PHYH) c.164delT, p.L55fsX12) mutation. Despite repeated plasmapheresis sessions and strict dietary surveillance for 20 years, her phytanic acid levels persistently stayed above the ideal target level of 100 μmol/L but remained below 400 μmol/L...
2017: JIMD Reports
https://www.readbyqxmd.com/read/27512501/management-of-venous-thromboembolism-secondary-to-ovarian-hyperstimulation-syndrome-a-case-report-documenting-the-first-use-of-a-superior-vena-caval-filter-for-upper-limb-venous-thromboembolism-in-pregnancy-and-the-difficulties-and-complications-relating-to
#17
Nicola Mitchell-Jones, Michael McEwan, Mark Johnson
The management of venous thromboembolism and subsequent pulmonary embolism in pregnancy remains hugely challenging. In this case, we report the first use of a superior vena caval filter in pregnancy as an adjunct to pharmacological anticoagulation. This is the first reported use of a superior vena caval filter in pregnancy. We discuss the complexities of managing thromboembolism in pregnancy and the peri-partum period.
June 2016: Obstetric Medicine
https://www.readbyqxmd.com/read/27509249/maternal-and-breast-milk-viral-load-impacts-of-adherence-on-peri-partum-hiv-infections-averted-the-ban-study
#18
Nicole L Davis, William C Miller, Michael G Hudgens, Charles S Chasela, Dorothy Sichali, Dumbani Kayira, Julie A E Nelson, Susan A Fiscus, Gerald Tegha, Deborah D Kamwendo, Joseph Rigdon, Jeffrey S A Stringer, Jonathan J Juliano, Sascha R Ellington, Athena P Kourtis, Denise J Jamieson, Charles Van Der Horst
BACKGROUND: Antiretroviral interventions are used to reduce HIV viral replication and prevent mother-to-child transmission. Viral suppression relies on adherence to antiretrovirals. METHODS: A two-phase study was conducted using data from the Breastfeeding, Antiretrovirals and Nutrition study. We included mothers randomized to 28 weeks of postpartum antiretrovirals with ≥1 plasma or breastmilk specimen. All mothers who transmitted HIV to their infants from 2-28 weeks (n=31) and 15% of mothers who did not (n=232) were included...
August 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27491276/simplified-and-standardized-intrapartum-management-can-yield-high-rates-of-successful-vbac-in-spontaneous-labor
#19
Mark P Hehir, Adam Mackie, Michael S Robson
OBJECTIVE: To examine the outcomes of vaginal birth after cesarean (VBAC) in women, in spontaneous labor, delivering after 37 weeks' gestation at an institution where trial of labor after a previous cesarean delivery (TOLAC) is encouraged and management of labor is standardized. METHODS: This retrospective cohort study included 3071 women with one previous cesarean only and no vaginal delivery who underwent a trial of labor from 2001 to 2011. Women were managed using the standardized "active management of labor" intrapartum protocol...
June 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27455907/characteristics-of-infants-exposed-to-maternal-tuberculosis-and-chemoprophylaxis-using-3-months-of-isoniazid-and-rifampicin
#20
Khakhu Tshilidzi Mathivha, Sithembiso Velaphi
BACKGROUND: Although the clinical features of infants with congenital tuberculosis (TB) are well established, the features of infants exposed to TB in utero including those who are non-infected, are not well reported. TB-exposed infants are at risk of developing TB post-delivery, and chemoprophylaxis, usually isoniazid, is therefore recommended. Isoniazid/rifampicin combined is an alternative, but little is known about its effectiveness. OBJECTIVE: To determine the clinical features of infants exposed to TB in utero and the proportion who develop TB infection and disease despite chemoprophylaxis with a 3-month course of isoniazid/rifampicin...
May 2017: Paediatrics and International Child Health
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