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https://www.readbyqxmd.com/read/28818840/hcn4-ion-channel-function-is-required-for-early-events-that-regulate-anatomical-left-right-patterning-in-a-nodal-and-lefty-asymmetric-gene-expression-independent-manner
#1
Vaibhav P Pai, Valerie Willocq, Emily J Pitcairn, Joan M Lemire, Jean-François Paré, Nian-Qing Shi, Kelly A McLaughlin, Michael Levin
Laterality is a basic characteristic of all life forms, from single cell organisms to complex plants and animals. For many metazoans, consistent left-right asymmetric patterning is essential for the correct anatomy of internal organs, such as the heart, gut, and brain; disruption of left-right asymmetry patterning leads to an important class of birth defects in human patients. Laterality functions across multiple scales, where early embryonic, subcellular and chiral cytoskeletal events are coupled with asymmetric amplification mechanisms and gene regulatory networks leading to asymmetric physical forces that ultimately result in distinct left and right anatomical organ patterning...
August 17, 2017: Biology Open
https://www.readbyqxmd.com/read/28809386/complications-of-bariatric-surgery-what-you-can-expect-to-see-in-your-gi-practice
#2
REVIEW
Allison R Schulman, Christopher C Thompson
Obesity is one of the most significant health problems worldwide. Bariatric surgery has become one of the fastest growing operative procedures and has gained acceptance as the leading option for weight-loss. Despite improvement in the performance of bariatric surgical procedures, complications are not uncommon. There are a number of unique complications that arise in this patient population and require specific knowledge for proper management. Furthermore, conditions unrelated to the altered anatomy typically require a different management strategy...
August 15, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28799849/public-health-activist-skills-pyramid-a-model-for-implementing-health-in-all-policies
#3
Behzad Damari, Elham Ehsani Chimeh
Affecting public health for society requires various competencies. In fact, the prerequisite for the implementation of health in all policies should be effectiveness of public health activists (PHAs) in these competencies. This study aims to determine the competencies of the activists in public health. The present qualitative study reviewed the literature and adopted qualitative methods like content analysis, stakeholder interviews, and conducted focus group discussions with related experts. In each stage, the required competencies were extracted through drawing the main action processes of a PHA...
August 11, 2017: Social Work in Public Health
https://www.readbyqxmd.com/read/28795411/does-ultrasound-enhanced-instruction-of-musculoskeletal-anatomy-improve-physical-examination-skills-of-first-year-medical-students
#4
Bryant J Walrod, Allison Schroeder, Mark J Conroy, Laura C Boucher, Marcia Bockbrader, David P Way, Kendra L McCamey, Clinton A Hartz, Michael A Jonesco, David P Bahner
OBJECTIVES: Ultrasound imaging is commonly used to teach basic anatomy to medical students. The purpose of this study was to determine whether learning musculoskeletal anatomy with ultrasound improved performance on medical students' musculoskeletal physical examination skills. METHODS: Twenty-seven first-year medical students were randomly assigned to 1 of 2 instructional groups: either shoulder or knee. Both groups received a lecture followed by hands-on ultrasound scanning on live human models of the assigned joint...
August 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28756412/heartfelt-images-learning-cardiac-science-artistically
#5
Carol Ann Courneya
There are limited curricular options for medical students to engage in art-making during their training. Yet, it is known that art-making confers a variety of benefits related to learning. This qualitative study utilises a visual methodology to explore students' art-making in the context of the cardiovascular sciences. The existence of a multiyear repository of medical/dental student generated, cardiac-inspired art, collected over 6 years, provided the opportunity to explore the nature of the art made. The aim was to categorise the art produced, as well as the depth and breadth of understanding required to produce the art...
July 29, 2017: Medical Humanities
https://www.readbyqxmd.com/read/28749850/midline-suboccipital-endoscopic-transcerebellomedullary-fissure-keyhole-approach
#6
Lin Yang, Hengzhu Zhang, Xingdong Wang, Zhengcun Yan, Lang Chen, Xiaoyan Ji, Jun Dong
OBJECTIVE: To study the endoscopic anatomy of the 4th ventricle and lateral brainstem regions via the midline suboccipital endoscopic transcerebellomedullary fissure keyhole approach assisted by a neuronavigation system and discuss the feasibility and indications of this approach. MATERIALS AND METHODS: Craniotomy procedures performed via the midline suboccipital endoscopic transcerebellomedullary fissure keyhole approach were simulated on 8 adult cadaveric heads fixed by formalin, and the related anatomic structures in the 4th ventricles or around the brainstem were observed through the 0° endoscope or alternatively 30° one...
July 26, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28746271/facial-assessment-and-injection-guide-for-botulinum-toxin-and-injectable-hyaluronic-acid-fillers-focus-on-the-upper-face
#7
Maurício de Maio, Arthur Swift, Massimo Signorini, Steven Fagien
Techniques for the administration of injectable fillers and neuromodulators for facial aesthetic rejuvenation and enhancement continue to evolve. As the number of physicians with limited experience in providing aesthetic treatments expands, the need for guidance and training from more experienced injectors has become apparent. The use of a slow, careful, and methodical injection technique is imperative in all treatment settings and for all facial areas. Constant attention to local anatomy, particularly arteries, veins, and nerve bundles, is critical for minimizing complications...
August 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28728324/the-chicken-thigh-adductor-profundus-free-muscle-flap-a-novel-validated-non-living-microsurgery-simulation-training-model
#8
Georgios Pafitanis, Yasmine Serrar, Maria Raveendran, Ali Ghanem, Simon Myers
BACKGROUND: Simulation training is becoming an increasingly important component of skills acquisition in surgical specialties, including Plastic Surgery. Non-living simulation models have an established place in Plastic Surgical microsurgery training, and support the principles of replacement, reduction and refinement of animal use. A more sophisticated version of the basic chicken thigh microsurgery model has been developed to include dissection of a type 1-muscle flap and is described and validated here...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28723767/return-of-the-cadaver-key-role-of-anatomic-dissection-for-plastic-surgery-resident-training
#9
Swenn Maxence Krähenbühl, Paul Čvančara, Thomas Stieglitz, Raphaël Bonvin, Murielle Michetti, Marjorie Flahaut, Sébastien Durand, Lina Deghayli, Lee Ann Applegate, Wassim Raffoul
Successful Plastic Surgery Residency training is subjected to evolving society pressure of lower hourly work weeks imposed by external committees, labor laws, and increased public awareness of patient care quality. Although innovative measures for simulation training of surgery are appearing, there is also the realization that basic anatomy training should be re-enforced and cadaver dissection is of utmost importance for surgical techniques.In the development of new technology for implantable neurostimulatory electrodes for the management of phantom limb pain in amputee patients, a design of a cadaveric model has been developed with detailed steps for innovative transfascicular insertion of electrodes...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28719968/training-in-endoscopy-endoscopic-retrograde-cholangiopancreatography
#10
REVIEW
Jaihwan Kim
Endoscopic retrograde cholangiopancreatography (ERCP) is a key endoscopy skill used to diagnose and treat pancreatobiliary diseases. However, its diagnostic use is decreasing in favor of other less invasive methods such as magnetic resonance cholangiopancreatography and endoscopic ultrasound. Alternatively, its use has become more important in the therapeutic area. ERCP trainees must know the anatomy and physiology of the pancreatobiliary system, several key basic skills, and complications of a successful procedure...
July 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28715313/the-visible-human-project-from-body-to-bits
#11
Michael J Ackerman
Atlases of anatomy have long been a mainstay for visualizing and identifying features of the human body [1]. Many are constructed of idealized illustrations rendered so that structures are presented as three-dimensional (3-D) pictures. Others have employed photographs of actual dissections. Still others are composed of collections of artist renderings of organs or areas of interest. All rely on a basically two-dimensional (2-D) graphic display to depict and allow for a better understanding of a complicated 3-D structure...
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28700420/comparison-of-2d-and-3d-video-displays-for-teaching-vitreoretinal-surgery
#12
Nisarg Chhaya, Omar Helmy, Niloofar Piri, Agustina Palacio, Shlomit Schaal
PURPOSE: To compare medical students' learning uptake and understanding of vitreoretinal surgeries by watching either 2D or 3D video recordings. METHODS: Three vitreoretinal procedures (tractional retinal detachment, exposed scleral buckle removal, and four-point scleral fixation of an intraocular lens [TSS]) were recorded simultaneously with a conventional recorder for two-dimensional viewing and a VERION 3D HD system using Sony HVO-1000MD for three-dimensional viewing...
July 11, 2017: Retina
https://www.readbyqxmd.com/read/28696848/an-interventionist-s-guide-to-endocrine-consultations
#13
Eric J Monroe, Benjamin W Carney, Christopher R Ingraham, Guy E Johnson, Karim Valji
Endocrinopathies are a heterogeneous group of disorders often resulting from pathologic sources of hormone production. When the clinical scenario, laboratory testing, and noninvasive imaging fail to aid confident identification of the source of hormone excess, endocrine venous sampling may localize obscure lesions to guide subsequent treatment. Knowledge of basic hormone signaling pathways, common pathophysiologic disruptions of these pathways, and serologic evaluation fosters informed conversations with referring physicians and effective patient selection...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28690437/the-use-of-modular-electronic-neuron-simulators-for-neural-circuit-construction-produces-learning-gains-in-an-undergraduate-anatomy-and-physiology-course
#14
Andrew Petto, Zachary Fredin, Joseph Burdo
During the spring of 2016 at the University of Wisconsin-Milwaukee, we implemented a novel educational technology designed to teach undergraduates about the nervous system while allowing them to physically construct their own neural circuits. Modular, electronic neuron simulators called NeuroBytes were used by the students in BIOSCI202 Anatomy and Physiology I, a four-credit course consisting of three hours per week each of lecture and laboratory time. 162 students participated in the laboratory sessions that covered reflexes; 83 in the experimental sections used the NeuroBytes to build a model of the patellar tendon reflex, while 79 in the control sections participated in alternate reflex curricula...
2017: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/28674987/neurodegeneration-and-pathology-in-epilepsy-clinical-and-basic-perspectives
#15
Jordan S Farrell, Marshal D Wolff, G Campbell Teskey
Epilepsy is commonly associated with a number of neurodegenerative and pathological alterations in those areas of the brain that are involved in repeated electrographic seizures. These most prominently include neuron loss and an increase in astrocyte number and size but may also include enhanced blood-brain barrier permeability, the formation of new capillaries, axonal sprouting, and central inflammation. In animal models in which seizures are either repeatedly elicited or are self-generated, a similar set of neurodegenerative and pathological alterations in brain anatomy are observed...
2017: Advances in Neurobiology
https://www.readbyqxmd.com/read/28666671/arthroscopic-management-of-elbow-osteoarthritis
#16
REVIEW
Leo T Kroonen, Samantha L Piper, Andrew C Ghatan
The incidence of osteoarthritis in the general population is low, but it can be seen in manual laborers, throwing athletes, and people dependent on crutches and wheelchairs. Patients often complain of pain at the terminal extents of motion, and imaging shows osteophyte formation at the tips of the coronoid and olecranon processes as well as thickening of the bone between the coronoid and the olecranon fossae. Recent advances in arthroscopic instrumentation and techniques have led to a growing interest in the arthroscopic treatment of elbow osteoarthritis...
June 28, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28665854/morphometric-analysis-of-the-posterior-cranial-fossa-in-syndromic-and-nonsyndromic-craniosynostosis
#17
Thomas Beez, David Koppel, Meharpal Sangra
Posterior cranial fossa (PCF) anatomy can be abnormal in craniosynostosis, and hindbrain herniation may occur. This study analyzed PCF anatomy in single suture and complex craniosynostosis.Children with craniosynostosis and age-matched controls were identified. Cephalic index (CI) for cranial vault and PCF as well as tentorial (TA) and occipital angles (OA) were measured on preoperative imaging.Children with syndromic (N = 6), bicoronal (N = 4), sagittal (N = 12), and metopic synostosis (N = 4) as well as controls (N = 10) were enrolled...
July 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28664494/can-liming-change-root-anatomy-biomass-allocation-and-trace-element-distribution-among-plant-parts-of-salix-%C3%A3-smithiana-in-trace-element-polluted-soils
#18
Stanislava Vondráčková, Pavel Tlustoš, Jiřina Száková
Willows (Salix spp.) are considered to be effective for the phytoremediation of trace elements from contaminated soils, but their efficiency is limited in heavily polluted soils because of poor growth. Liming can be a desirable measure to decrease the plant availability of elements, resulting in improved plant development. Notably, large root area and maximum soil penetration are basic parameters that improve the efficiency of phytoremediation. The impact of soil chemical properties on willow root anatomy and the distribution of trace elements below-ground have rarely been studied...
June 29, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28641752/congenital-diaphragmatic-hernia-associated-pulmonary-hypertension
#19
Matthew T Harting
Congenital diaphragmatic hernia (CDH) is a complex entity wherein a diaphragmatic defect allows intrathoracic herniation of intra-abdominal contents and both pulmonary parenchymal and vascular development are stifled. Pulmonary pathology and pathophysiology, including pulmonary hypoplasia and pulmonary hypertension, are hallmarks of CDH and are associated with disease severity. Pulmonary hypertension (PH) is sustained, supranormal pulmonary arterial pressure, and among patients with CDH (CDH-PH), is driven by hypoplastic pulmonary vasculature, including alterations at the molecular, cellular, and tissue levels, along with pathophysiologic pulmonary vasoreactivity...
June 2017: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/28636959/the-enteric-network-interactions-between-the-immune-and-nervous-systems-of-the-gut
#20
REVIEW
Bryan B Yoo, Sarkis K Mazmanian
Interactions between the nervous and immune systems enable the gut to respond to the variety of dietary products that it absorbs, the broad spectrum of pathogens that it encounters, and the diverse microbiome that it harbors. The enteric nervous system (ENS) senses and reacts to the dynamic ecosystem of the gastrointestinal (GI) tract by translating chemical cues from the environment into neuronal impulses that propagate throughout the gut and into other organs in the body, including the central nervous system (CNS)...
June 20, 2017: Immunity
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