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https://www.readbyqxmd.com/read/28641752/congenital-diaphragmatic-hernia-associated-pulmonary-hypertension
#1
Matthew T Harting
Congenital diaphragmatic hernia (CDH) is a complex entity wherein a diaphragmatic defect allows intrathoracic herniation of intra-abdominal contents and both pulmonary parenchymal and vascular development are stifled. Pulmonary pathology and pathophysiology, including pulmonary hypoplasia and pulmonary hypertension, are hallmarks of CDH and are associated with disease severity. Pulmonary hypertension (PH) is sustained, supranormal pulmonary arterial pressure, and among patients with CDH (CDH-PH), is driven by hypoplastic pulmonary vasculature, including alterations at the molecular, cellular, and tissue levels, along with pathophysiologic pulmonary vasoreactivity...
June 2017: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/28636959/the-enteric-network-interactions-between-the-immune-and-nervous-systems-of-the-gut
#2
REVIEW
Bryan B Yoo, Sarkis K Mazmanian
Interactions between the nervous and immune systems enable the gut to respond to the variety of dietary products that it absorbs, the broad spectrum of pathogens that it encounters, and the diverse microbiome that it harbors. The enteric nervous system (ENS) senses and reacts to the dynamic ecosystem of the gastrointestinal (GI) tract by translating chemical cues from the environment into neuronal impulses that propagate throughout the gut and into other organs in the body, including the central nervous system (CNS)...
June 20, 2017: Immunity
https://www.readbyqxmd.com/read/28608992/student-and-recent-graduate-perspectives-on-radiological-imaging-instruction-during-basic-anatomy-courses
#3
Andrew W Phillips, Hunter Eason, Christopher M Straus
Recently, faculty at Pritzker School of Medicine, The University of Chicago, have made efforts to improve the depth of radiological anatomy knowledge that students have, but no insights exist as to student and resident opinions of how clinically helpful deep anatomical understanding is. A single-institution survey of second- and fourth-year medical students and postgraduate year 1-4 residents from 11 specialties, composed of five-point Likert questions, sample examination questions, and narrative response questions, was distributed in 2015...
June 13, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28608954/experience-from-an-optional-dissection-course-in-a-clinically-orientated-concept-to-complement-system-based-anatomy-in-a-reformed-curriculum
#4
Elisabeth Eppler, Steffen Serowy, Karl Link, Luis Filgueira
Profound anatomical knowledge is the basis for modern demands in medicine and surgery, but many countries worldwide including Australia and New Zealand have discontinued offering dissection courses to medical and dental students during the past decades. This educational project done in Australia aimed at enhancing basic and advanced anatomy teaching by engaging a sub-group of second-year undergraduate students of a compulsory prosection- and model-based anatomy course (n = 54/170) in an optional multimodal course, which should easily articulate with a vertical curriculum...
June 13, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28603708/revisiting-radial-forearm-free-flap-for-successful-venous-drainage
#5
REVIEW
Yong Hoon Cha, Woong Nam, In-Ho Cha, Hyung Jun Kim
Tissue defect reconstruction using radial forearm free flap (RFFF) is a common surgical technique whose success or failure is mainly dependent on venous drainage. RFFF has two major venous outflow systems, superficial and deep vein. Drainage methods include combining both systems or using one alone. This review aims to recapitulate the vascular anatomy and network of RFFF as well as shed light on deep vein as a reliable venous drainage system. We also discuss basic evidence for and advantages of single microanastomosis with coalesced vein to overcome technical difficulties associated with the deep vein system...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28602889/simple-and-reproducible-approaches-for-the-collection-of-select-porcine-ganglia
#6
David K Meyerholz, Leah R Reznikov
BACKGROUND: The anatomy and physiology of the pig nervous system is more similar to humans compared to traditional rodent models. This makes the pig an attractive model to answer questions relating to human health and disease. Yet the technical and molecular tools available to pig researchers are limited compared to rodent researchers NEW METHOD: We developed simple and rapid methods to isolate the trigeminal, nodose (distal vagal), and dorsal root ganglia from neonatal pigs. We selected these ganglia due to their broad applicability to basic science researchers and clinicians RESULTS: Use of these methods resulted in reproducible isolation of all three types of ganglia as validated by histological examination...
June 8, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28592171/next-generation-human-skin-constructs-as-advanced-tools-for-drug-development
#7
H E Abaci, Zongyou Guo, Yanne Doucet, Joanna Jacków, Angela Christiano
Many diseases, as well as side effects of drugs, manifest themselves through skin symptoms. Skin is a complex tissue that hosts various specialized cell types and performs many roles including physical barrier, immune and sensory functions. Therefore, modeling skin in vitro presents technical challenges for tissue engineering. Since the first attempts at engineering human epidermis in 1970s, there has been a growing interest in generating full-thickness skin constructs mimicking physiological functions by incorporating various skin components, such as vasculature and melanocytes for pigmentation...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28585841/-vascular-anatomy-and-abnormalities-of-retroperitoneal-pelvic-and-paraaortic-area-in-relation-to-the-radical-oncogynecological-surgery-individual-experiences
#8
L Minář, V Weinberger, M Felsinger
OBJECTIVE: The overview of vascular anatomy and abnormalities of retroperitoneal pelvic and paraaortic area in relation to the radical oncogynecological surgery. DESIGN: Retrospective study. SETTING: Gynecologic Oncology Center, Department of Obstetrics and Gynecology, Faculty of Medicine, Masaryk University and University Hospital Brno. MATERIAL AND METHODS: The overview of visualized vascular anatomy of retroperitoneal pelvic, infrarenal suprapelvic and subhepatic area in relation to the radical oncogynecological surgery...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28579047/surgical-procedures-of-the-distal-limb-for-treatment-of-sepsis-in-cattle
#9
REVIEW
David E Anderson, André Desrochers, Sarel R van Amstel
With a thorough knowledge of the anatomy of the foot, and basic surgical instruments, digit surgery can be performed in field situations. Sepsis of the distal interphalangeal and proximal interphalangeal joints should be treated surgically because conservative treatment is often ineffective. Most of the diseases described in this article are chronic and often the animals have been suffering for some time. Perioperative analgesia is important to alleviate the pain of those animals. All those procedures should be performed under local or regional anesthesia...
July 2017: Veterinary Clinics of North America. Food Animal Practice
https://www.readbyqxmd.com/read/28573551/two-dimensional-breast-dosimetry-improved-using-three-dimensional-breast-image-data
#10
REVIEW
John M Boone, Andrew M Hernandez, J Anthony Seibert
Conventional mammographic dosimetry has been developed over the past 40 years. Prior to the availability of high-resolution three-dimensional breast images, certain assumptions about breast anatomy were required. These assumptions were based on the information evident on two-dimensional mammograms; they included assumptions of thick skin, a uniform mixture of glandular and adipose tissue, and a median breast density of 50%. Recently, the availability of high-resolution breast CT studies has provided more accurate data about breast anatomy, and this, in turn, has provided the opportunity to update mammographic dosimetry...
June 1, 2017: Radiological Physics and Technology
https://www.readbyqxmd.com/read/28570033/quantitative-mri-and-spectroscopy-of-bone-marrow
#11
REVIEW
Dimitrios C Karampinos, Stefan Ruschke, Michael Dieckmeyer, Maximilian Diefenbach, Daniela Franz, Alexandra S Gersing, Roland Krug, Thomas Baum
Bone marrow is one of the largest organs in the human body, enclosing adipocytes, hematopoietic stem cells, which are responsible for blood cell production, and mesenchymal stem cells, which are responsible for the production of adipocytes and bone cells. Magnetic resonance imaging (MRI) is the ideal imaging modality to monitor bone marrow changes in healthy and pathological states, thanks to its inherent rich soft-tissue contrast. Quantitative bone marrow MRI and magnetic resonance spectroscopy (MRS) techniques have been also developed in order to quantify changes in bone marrow water-fat composition, cellularity and perfusion in different pathologies, and to assist in understanding the role of bone marrow in the pathophysiology of systemic diseases (e...
June 1, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28561922/master-in-oral-biology-program-a-path-to-addressing-the-need-for-future-dental-educators
#12
Margaret A Jergenson, Laura C Barritt, Barbara J O'Kane, Neil S Norton
In dental education, the anatomical sciences, which include gross anatomy, histology, embryology, and neuroanatomy, encompass an important component of the basic science curriculum. At Creighton University School of Dentistry, strength in anatomic science education has been coupled with a solid applicant pool to develop a novel Master of Science in Oral Biology, Anatomic Sciences track degree program. The program provides a heavy emphasis on developing teaching skills in predoctoral students as well as exposure to research processes to encourage the cohort to pursuing a career in academic dentistry...
May 31, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28560707/current-trends-in-tendinopathy-consensus-of-the-esska-basic-science-committee-part-i-biology-biomechanics-anatomy-and-an-exercise-based-approach
#13
REVIEW
F Abat, H Alfredson, M Cucchiarini, H Madry, A Marmotti, C Mouton, J M Oliveira, H Pereira, G M Peretti, D Romero-Rodriguez, C Spang, J Stephen, C J A van Bergen, L de Girolamo
Chronic tendinopathies represent a major problem in the clinical practice of sports orthopaedic surgeons, sports doctors and other health professionals involved in the treatment of athletes and patients that perform repetitive actions. The lack of consensus relative to the diagnostic tools and treatment modalities represents a management dilemma for these professionals. With this review, the purpose of the ESSKA Basic Science Committee is to establish guidelines for understanding, diagnosing and treating this complex pathology...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28560134/basics-of-elbow-arthroscopy-part-i-surface-anatomy-portals-and-structures-at-risk
#14
Christopher L Camp, Ryan M Degen, Joaquin Sanchez-Sotelo, David W Altchek, Joshua S Dines
As our knowledge and technology advance, the indications for elbow arthroscopy continue to grow rapidly. During this expansion, a number of new portals have been described and reported using variable nomenclature and location descriptions. Accordingly, a comprehensive review of these portals is warranted. Given the concern for potential iatrogenic injury to surrounding neurovascular structures, a discussion of these critical nerves and vessels is also timely. In this work, we review pertinent surface anatomy; portal nomenclature, locations, and utility; and review distances to the nearest structures at risk...
December 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28553418/analysis-of-the-literature-on-chronic-cough-in-children
#15
REVIEW
Marcello Bergamini, Ahmad Kantar, Renato Cutrera, Italian Pediatric Cough Interest Group
Throughout childhood, various developmental phenomena influence the cough reflex. Among these are the modifications in the anatomy and functions of the respiratory tract and the central and peripheral nervous systems. Moreover, after birth, the immunological response undergoes progressive transformations with the acquisition of immune memory processes. These conditions make infections and airway abnormalities the overwhelming cause of chronic cough in children and infants. In children, chronic cough should be treated on the basis of etiology...
2017: Open Respiratory Medicine Journal
https://www.readbyqxmd.com/read/28552391/where-are-we-the-anatomy-of-the-murine-cortical-meninges-revisited-for-intravital-imaging-immunology-and-clearance-of-waste-from-the-brain
#16
REVIEW
Jonathan A Coles, Elmarie Myburgh, James M Brewer, Paul G McMenamin
Rapid progress is being made in understanding the roles of the cerebral meninges in the maintenance of normal brain function, in immune surveillance, and as a site of disease. Most basic research on the meninges and the neural brain is now done on mice, major attractions being the availability of reporter mice with fluorescent cells, and of a huge range of antibodies useful for immunocytochemistry and the characterization of isolated cells. In addition, two-photon microscopy through the unperforated calvaria allows intravital imaging of the undisturbed meninges with sub-micron resolution...
May 25, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28547248/inferior-glenoid-fossa-fractures-patho-anatomy-and-results-of-operative-treatment
#17
Jan Bartoníček, Michal Tuček, Daniel Klika
INTRODUCTION: A typical feature of inferior glenoid fractures is a distal fragment separated from the glenoid fossa. In most cases, the inferior glenoid fractures are associated with a fracture of the scapular body. However, there are no detailed studies of inferior glenoid fractures, and only brief mentions can be found in the literature in this respect. MATERIAL AND METHODS: The basic group comprised 42 patients, with the mean age of 48 years, who sustained 42 fractures of the inferior glenoid...
May 25, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28545616/peer-assisted-learning-pal-in-undergraduate-medical-education-an-overview
#18
REVIEW
Anne Herrmann-Werner, Regina Gramer, Rebecca Erschens, Christoph Nikendei, Annette Wosnik, Jan Griewatz, Stephan Zipfel, Florian Junne
Peer-assisted learning (PAL) has a long tradition and is nowadays implemented in the curricula of most medical faculties. Besides traditional areas of application like problem-based learning, anatomy, or CPR, more and more departments and institutes have established PAL as part of their everyday teaching. This narrative review provides some background information and basic definitions of PAL. It offers an overview on features and determinants as well as underlying learning theories and developments in PAL. In addition, motives for implementation are highlighted followed by a comparison of advantages and disadvantages...
April 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28538370/radiographic-anatomical-relationship-between-spinous-process-and-pedicle-in-thoracolumbar-and-lumbar-spine
#19
Xingang Cui, Guodong Wang
Pedicle screws are widely used in spinal surgeries, but it remains technically demanding to place. There are numerous studies on the anatomy of pedicle; however, there is very little insight on the relationship between the pedicle and the spinous process, which is an important part of the spinal posterior column.The aim of the study was to investigate the radiographic anatomical relationship between spinous processes and pedicles in the thoracolumbar and lumbar spine, in order to reveal a novel entrance point for pedicle screw insertion...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28535851/dancers-perceived-and-actual-knowledge-of-anatomy
#20
Dana H Kotler, Meaghan Lynch, Daniel Cushman, Jason Hu, Jocelyn Garner
Dancers are highly susceptible to musculoskeletal injuries and frequently require interaction with medical professionals. While many dancers have a finely tuned awareness of their bodies, their knowledge of the fundamentals of human anatomy is not uniform. There is a paucity of literature on the benefits of human anatomy education in dancers, though it seems intuitive that there should be a relationship. The purpose of this study was to assess dancers' perceived and actual knowledge of basic musculoskeletal anatomy and its relationship to function...
June 15, 2017: Journal of Dance Medicine & Science
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