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https://www.readbyqxmd.com/read/28728869/aesthetic-outcome-and-complications-of-simple-interrupted-versus-running-subcuticular-sutures-in-facial-surgery-a-randomized-controlled-trial
#1
Xiaomeng Liu, Patty J Nelemans, Lisa D S Frenk, Helma Sengers, Stephania M H Tuinder, Peter M Steijlen, Klara Mosterd, Nicole W J Kelleners-Smeets
BACKGROUND: The suturing technique and its associated complications could affect cosmetic outcome after facial surgery. Literature on this topic is limited. OBJECTIVE: To compare the cosmetic results 12 months after treatment and complications associated with simple interrupted sutures (SIS) versus running subcuticular sutures (RSS) in facial surgery. METHODS: A randomized, controlled multicenter trial was performed. Adults receiving dermatologic surgery on the face were randomized to receive SIS or RSS for wound closure...
July 17, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28724770/rgs-cam-detects-and-counteracts-viral-rna-silencing-suppressors-in-plant-immune-priming
#2
Eun Jin Jeon, Kazuki Tadamura, Taiki Murakami, Jun-Ichi Inaba, Bo Min Kim, Masako Sato, Go Atsumi, Kazuyuki Kuchitsu, Chikara Masuta, Kenji S Nakahara
Primary infection of a plant with a pathogen that causes high accumulation of salicylic acid in the plant typically via a hypersensitive response confers enhanced resistance against secondary infection with a broad spectrum of pathogens, including viruses. This phenomenon is called systemic acquired resistance (SAR), which is a plant-priming for adaption to repeated biotic stress. However, the molecular mechanisms of SAR-mediated enhanced inhibition, especially of virus infection, remain unclear. Here, we show that SAR against cucumber mosaic virus (CMV) in tobacco plants (Nicotiana tabacum) involves a calmodulin-like protein, rgs-CaM...
July 19, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28711187/development-of-an-in-vitro-diaphragm-motion-reproduction-system
#3
Ai-Ho Liao, Ho-Chiao Chuang, Ming-Chih Shih, Hsiao-Yu Hsu, Der-Chi Tien, Chia-Chun Kuo, Shiu-Chen Jeng, Jeng-Fong Chiou
This study developed an in vitro diaphragm motion reproduction system (IVDMRS) based on noninvasive and real-time ultrasound imaging to track the internal displacement of the human diaphragm and diaphragm phantoms with a respiration simulation system (RSS). An ultrasound image tracking algorithm (UITA) was used to retrieve the displacement data of the tracking target and reproduce the diaphragm motion in real time using a red laser to irradiate the diaphragm phantom in vitro. This study also recorded the respiration patterns in 10 volunteers...
July 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28708067/enhanced-handover-decision-algorithm-in-heterogeneous-wireless-network
#4
Radhwan Mohamed Abdullah, Zuriati Ahmad Zukarnain
Transferring a huge amount of data between different network locations over the network links depends on the network's traffic capacity and data rate. Traditionally, a mobile device may be moved to achieve the operations of vertical handover, considering only one criterion, that is the Received Signal Strength (RSS). The use of a single criterion may cause service interruption, an unbalanced network load and an inefficient vertical handover. In this paper, we propose an enhanced vertical handover decision algorithm based on multiple criteria in the heterogeneous wireless network...
July 14, 2017: Sensors
https://www.readbyqxmd.com/read/28695379/expression-of-prostaglandin-e2-receptor-subtypes-in-human-pterygium-and-normal-conjunctiva-immunohistochemical-study
#5
Erdem Dinç, Özer Dursun, Banu Yılmaz, Mustafa Vatansever, A Ayça Sarı, Özlem Yıldırım, Ufuk Adıgüzel
PURPOSE: In the present study, we aimed to evaluate the expression of EP receptors in primary and recurrent human pterygium tissues. METHODS: Pterygium samples were collected from 65 patients with primary pterygium and 16 patients with recurrent pterygium. Normal conjunctival tissues were collected from nasal interpalpebral area from 17 patients without systemic and any other ocular pathology. Expression of EP receptors was evaluated by immunohistochemistry. The median value for each receptor staining score (RSS) was determined in normal conjunctival specimens...
July 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28694431/key-role-for-the-organic-anion-transporters-oat1-and-oat3-in-the-in-vivo-handling-of-uremic-toxins-and-solutes
#6
Wei Wu, Kevin T Bush, Sanjay K Nigam
In vitro data indicates that the kidney proximal tubule (PT) transporters of uremic toxins and solutes (e.g., indoxyl sulfate, p-cresol sulfate, kynurenine, creatinine, urate) include two "drug" transporters of the organic anion transporter (OAT) family: OAT1 (SLC22A6, originally NKT) and OAT3 (SLC22A8). Here, we have examined new and prior metabolomics data from the Oat1KO and Oat3KO, as well as newly obtained metabolomics data from a "chemical double" knockout (Oat3KO plus probenecid). This gives a picture of the in vivo roles of OAT1 and OAT3 in the regulation of the uremic solutes and supports the centrality of these "drug" transporters in independently and synergistically regulating uremic metabolism...
July 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28693733/a-fluorescent-dyad-with-large-emission-shift-for-discrimination-of-cysteine-homocysteine-from-glutathione-and-hydrogen-sulfide-and-the-application-of-bioimaging
#7
Xueling Yang, Longwei He, Kaixin Xu, Weiying Lin
Biothiols, as reactive sulfur species (RSS), play important roles in human physiology, and they have a close connection of generation and metabolism pathways among of them. It is challenging to discriminate biothiols from each other due to the similar chemical structures and properties of them. Herein, we develop a fluorescent hybrid dyad (CS-NBD) for efficiently discriminating cysteine (Cys)/homocysteine (Hcy) from glutathione (GSH) and hydrogen sulfide (H2S) by a dual-channel detection method. CS-NBD performs inherently no fluorescence in ranging from visible to near infrared region...
August 15, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28661910/determination-of-reynolds-shear-stress-level-for-hemolysis
#8
Choon-Sik Jhun, Megan A Stauffer, John D Reibson, Eric E Yeager, Raymond K Newswanger, Joshua O Taylor, Keefe B Manning, William J Weiss, Gerson Rosenberg
Reynolds shear stress (RSS) has served as a metric for the effect of turbulence on hemolysis. Forstrom (1969) and Sallam and Hwang (1984) determined the RSS threshold for hemolysis to be 50,000 and 4,000 dyne/cm, respectively, using a turbulent jet. Despite the order of magnitude discrepancy, the threshold by Sallam and Hwang has been frequently cited for hemolytic potential in blood pumps. We recreated Sallam apparatus (SA) to resolve this discrepancy and provide additional data to be used in developing a more accurate hemolysis model...
June 15, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28656172/sulfide-homeostasis-and-nitroxyl-intersect-via-formation-of-reactive-sulfur-species-in-staphylococcus-aureus
#9
Hui Peng, Jiangchuan Shen, Katherine A Edmonds, Justin L Luebke, Anne K Hickey, Lauren D Palmer, Feng-Ming James Chang, Kevin A Bruce, Thomas E Kehl-Fie, Eric P Skaar, David P Giedroc
Staphylococcus aureus is a commensal human pathogen and a major cause of nosocomial infections. As gaseous signaling molecules, endogenous hydrogen sulfide (H2S) and nitric oxide (NO·) protect S. aureus from antibiotic stress synergistically, which we propose involves the intermediacy of nitroxyl (HNO). Here, we examine the effect of exogenous sulfide and HNO on the transcriptome and the formation of low-molecular-weight (LMW) thiol persulfides of bacillithiol, cysteine, and coenzyme A as representative of reactive sulfur species (RSS) in wild-type and ΔcstR strains of S...
May 2017: MSphere
https://www.readbyqxmd.com/read/28641437/structure-and-binding-energy-of-the-h2s-dimer-at-the-ccsd-t-complete-basis-set-limit
#10
Kono H Lemke
This study presents results for the binding energy and geometry of the H2S dimer which have been computed using Møller-Plesset perturbation theory (MP2, MP4) and coupled cluster (CCSD, CCSD(T)) calculations with basis sets up to aug-cc-pV5Z. Estimates of De, EZPE, Do, and dimer geometry have been obtained at each level of theory by taking advantage of the systematic convergence behavior toward the complete basis set (CBS) limit. The CBS limit binding energy values of De are 1.91 (MP2), 1.75 (MP4), 1.41 (CCSD), and 1...
June 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28637792/reactive-sulfur-species-inactivate-ca-2-calmodulin-dependent-protein-kinase-iv-via-s-polysulfidation-of-its-active-site-cysteine-residue
#11
Tsuyoshi Takata, Hideshi Ihara, Naoya Hatano, Yukihiro Tsuchiya, Takaaki Akaike, Yasuo Watanabe
Reactive sulfur species (RSS) modulate protein functions via S- polysulfidation of reactive Cys residues. Here, we report that Ca(2+)/calmodulin (CaM)-dependent protein kinase IV (CaMKIV) was reversibly inactivated by RSS via polysulfidation of the active site Cys residue. CaMKIV is phosphorylated at Thr(196) by its upstream CaMK kinase (CaMKK), resulting in the induction of its full activity. In vitro incubation of CaMKIV with the exogenous RSS donors Na2Sn ( n = 2-4) resulted in dose-dependent inhibition of the CaMKK-induced phospho-Thr(196) and consequent inactivation of the enzyme activity...
June 21, 2017: Biochemical Journal
https://www.readbyqxmd.com/read/28631603/a-single-point-mutation-in-tomato-spotted-wilt-virus-nss-protein-is-sufficient-to-overcome-tsw-gene-mediated-resistance-in-pepper
#12
Asztéria Almási, Katalin Nemes, Zsófia Csömör, István Tóbiás, László Palkovics, Katalin Salánki
The nonstructural protein (NSs) of Tomato spotted wilt virus (TSWV) was previously identified as an avirulence determinant for Tsw-based resistance on pepper. The NSs of wild-type (WT) and resistance-breaking (RB) TSWV strains isolated in Hungary had only two amino acid substitutions (104, 461). We have analysed the ability of the NSs and their point mutant variants to trigger Tsw-mediated hypersensitive responses and RNA silencing suppressor (RSS) activity in patch assays. We identified a single amino acid change at position 104 (T-A) that was responsible for the necrosis induction or loss, while a significant difference was not detected in the RSS activity of the two parental strains...
June 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28621378/the-hypothiocyanite-radical-oscn-and-its-isomers
#13
Zhuang Wu, Jian Xu, Qifan Liu, Xuelin Dong, Dingqing Li, Nicole Holzmann, Gernot Frenking, Tarek Trabelsi, Joseph S Francisco, Xiaoqing Zeng
A biologically relevant reactive sulfur species (RSS), the hypothiocyanite radical OSCN, is generated in the gas phase through flash vacuum pyrolysis (FVP) of trifluoromethyl sulfinyl cyanide CF3S(O)CN at ca. 1000 K. Upon UV light irradiation (365 nm), OSCN rearranges to novel isomers OSNC and SOCN, and further visible light irradiation (400 ± 20 nm) leads to reverse isomerization. The identification of OSCN, OSNC, and SOCN in cryogenic matrices (Ar and N2, 2.8 K) with IR spectroscopy is supported by quantum chemical calculations up to the CCSD(T)-F12/VTZ-F12 level...
June 28, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28612383/a-new-player-in-bacterial-sulfide-inducible-transcriptional-regulation
#14
David P Giedroc
Although hydrogen sulfide (H2 S) is perhaps best known as a toxic gas, the electron-rich H2 S functions as an energy source and electron donor for chemolithotrophic and photosynthetic bacteria, via sulfide oxidation, and is a universal substrate for cysteine biosynthesis. These distinct harmful and beneficial roles of H2 S suggest the need to 'sense' prevailing concentrations of sulfide and downstream reactive sulfur species (RSS) and regulate the expression of genes mediating sulfide homeostasis. The paper by Li et al...
June 14, 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/28605412/accuracy-profiles-for-analyzing-residual-solvents-in-textiles-by-gc-ms
#15
Qibei Bao, Kejie Fu, Qingqing Ren, Yingying Zhong, Dan Qian
Excess residual solvents (RSs) in clothes or other textiles could be toxic and pose risks to both humans and the environment. N,N-Dimethylformamide (DMF), N,N-dimethylacetamide (DMAc) and 1-methyl-2-pyrrolidinone (NMP) are important chemicals frequently used as solvents in the textile industry. Several organizations have proposed limiting DMF, DMAc and NMP in textiles, but an appropriate detection method has not been proposed. A sensitive GC-MS method for the quantification of DMF, DMAc and NMP in textiles was developed...
June 9, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28598358/a-smartphone-indoor-localization-algorithm-based-on-wlan-location-fingerprinting-with-feature-extraction-and-clustering
#16
Junhai Luo, Liang Fu
With the development of communication technology, the demand for location-based services is growing rapidly. This paper presents an algorithm for indoor localization based on Received Signal Strength (RSS), which is collected from Access Points (APs). The proposed localization algorithm contains the offline information acquisition phase and online positioning phase. Firstly, the AP selection algorithm is reviewed and improved based on the stability of signals to remove useless AP; secondly, Kernel Principal Component Analysis (KPCA) is analyzed and used to remove the data redundancy and maintain useful characteristics for nonlinear feature extraction; thirdly, the Affinity Propagation Clustering (APC) algorithm utilizes RSS values to classify data samples and narrow the positioning range...
June 9, 2017: Sensors
https://www.readbyqxmd.com/read/28588521/the-effect-of-extreme-response-and-non-extreme-response-styles-on-testing-measurement-invariance
#17
Min Liu, Allen G Harbaugh, Jeffrey R Harring, Gregory R Hancock
Extreme and non-extreme response styles (RSs) are prevalent in survey research using Likert-type scales. Their effects on measurement invariance (MI) in the context of confirmatory factor analysis are systematically investigated here via a Monte Carlo simulation study. Using the parameter estimates obtained from analyzing a 2007 Trends in International Mathematics and Science Study data set, a population model was constructed. Original and contaminated data with one of two RSs were generated and analyzed via multi-group confirmatory factor analysis with different constraints of MI...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28582558/promed-mail-22-years-of-digital-surveillance-of-emerging-infectious-diseases
#18
Malwina Carrion, Lawrence C Madoff
ProMED-mail (ProMED) was launched in 1994 as an email service to identify unusual health events related to emerging and re-emerging infectious diseases and toxins affecting humans, animals and plants. It is used daily by public health leaders, government officials at all levels, physicians, veterinarians and other healthcare workers, researchers, private companies, journalists and the general public. Reports are produced and commentary provided by a global team of subject matter experts in a variety of fields including virology, parasitology, epidemiology, entomology, veterinary and plant disease specialists...
May 1, 2017: International Health
https://www.readbyqxmd.com/read/28569776/hiv-integrase-inhibitor-elvitegravir-impairs-rag-functions-and-inhibits-v-d-j-recombination
#19
Mayilaadumveettil Nishana, Namrata M Nilavar, Rupa Kumari, Monica Pandey, Sathees C Raghavan
Integrase inhibitors are a class of antiretroviral drugs used for the treatment of AIDS that target HIV integrase, an enzyme responsible for integration of viral cDNA into host genome. RAG1, a critical enzyme involved in V(D)J recombination exhibits structural similarity to HIV integrase. We find that two integrase inhibitors, Raltegravir and Elvitegravir, interfered with the physiological functions of RAGs such as binding, cleavage and hairpin formation at the recombination signal sequence (RSS), though the effect of Raltegravir was limited...
June 1, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28556823/belief-interval-of-dempster-shafer-theory-for-line-of-sight-identification-in-indoor-positioning-applications
#20
Jinwu Wu, Tingyu Zhao, Shang Li, Chung-Ming Own
Location data are among the most widely used contextual data in context-aware and ubiquitous computing applications. Numerous systems with distinct deployment costs and levels of positioning accuracy have been developed over the past decade for indoor positioning purposes. The most useful method focuses on the received signal strength (RSS) and provides a set of signal transmission access points. Furthermore, most positioning systems are based on non-line-of-sight (NLOS) rather than line-of-sight (LOS) conditions, and this cause ranging errors for location predictions...
May 30, 2017: Sensors
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