Jasper Iske, Andreas Schroeter, Samuel Knoedler, Timo Z Nazari-Shafti, Leonard Wert, Maximilian J Roesel, Felix Hennig, Adelheid Niehaus, Christian Kuehn, Fabio Ius, Volkmar Falk, Moritz Schmelzle, Arjang Ruhparwar, Axel Haverich, Christoph Knosalla, Stefan G Tullius, Florian W R Vondran, Bettina Wiegmann
Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid organs with primary application in allogeneic organ transplantation. EVMP has been established as an alternative to the standard of care static-cold preservation, allowing for prolonged preservation and real-time monitoring of organ quality while reducing/preventing ischemia-reperfusion injury. Moreover, it has paved the way to involve expanded criteria donors, e.g., after circulatory death, thus expanding the donor organ pool...
2023: Frontiers in Cardiovascular Medicine