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https://www.readbyqxmd.com/read/29771780/biomarkers-of-aging-in-hiv-infected-children-on-suppressive-antiretroviral-therapy
#1
Stephanie Shiau, Renate Strehlau, Jing Shen, Avy Violari, Faeezah Patel, Afaaf Liberty, Marc Foca, Shuang Wang, Mary Beth Terry, Michael T Yin, Ashraf Coovadia, Elaine J Abrams, Stephen M Arpadi, Louise Kuhn
BACKGROUND: Data on accelerated aging in HIV-infected children are limited. In this study we assess two biomarkers of aging - telomere length and DNA methylation (DNAm) age - in a cohort of early-treated HIV-infected children and compare these aging biomarkers to HIV-exposed uninfected (HEU) and HIV-unexposed uninfected (HUU) children. SETTING: Cross-sectional study of 120 HIV-infected, 33 HEU, and 25 HUU children enrolled in a cohort study in Johannesburg, South Africa...
April 27, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29764478/improved-symptomatic-functional-and-fluoroscopic-outcomes-following-serial-series-of-three-double-balloon-dilation-for-cricopharyngeus-muscle-dysfunction
#2
Derrick R Randall, Lisa M Evangelista, Maggie A Kuhn, Peter C Belafsky
BACKGROUND: Cricopharyngeus muscle dysfunction (CPMD) is a common cause of dysphagia. We employ a progressive series of three double-balloon dilations separated by 4-6 weeks between procedures as a primary treatment option. The purpose of this study was to evaluate subjective, functional and objective improvement in swallowing after three serial dilations for CPMD. METHODS: We retrospectively evaluated patients between June 1, 2014, and June 30, 2016, who underwent a series of three double-balloon dilations for CPMD...
May 15, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29754305/changes-to-taxonomy-and-the-international-code-of-virus-classification-and-nomenclature-ratified-by-the-international-committee-on-taxonomy-of-viruses-2018
#3
Andrew M Q King, Elliot J Lefkowitz, Arcady R Mushegian, Michael J Adams, Bas E Dutilh, Alexander E Gorbalenya, Balázs Harrach, Robert L Harrison, Sandra Junglen, Nick J Knowles, Andrew M Kropinski, Mart Krupovic, Jens H Kuhn, Max L Nibert, Luisa Rubino, Sead Sabanadzovic, Hélène Sanfaçon, Stuart G Siddell, Peter Simmonds, Arvind Varsani, Francisco Murilo Zerbini, Andrew J Davison
This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses in February 2018. A total of 451 species, 69 genera, 11 subfamilies, 9 families and one new order were added to the taxonomy. The current totals at each taxonomic level now stand at 9 orders, 131 families, 46 subfamilies, 803 genera and 4853 species. A change was made to the International Code of Virus Classification and Nomenclature to allow the use of the names of people in taxon names under appropriate circumstances...
May 12, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29721293/tree-seed-rain-and-seed-removal-but-not-the-seed-bank-impede-forest-recovery-in-bracken-pteridium-aquilinum-l-kuhn-dominated-clearings-in-the-african-highlands
#4
Fredrick Ssali, Stein R Moe, Douglas Sheil
Considerable areas dominated by bracken Pteridium aquilinum (L.) Kuhn occur worldwide and are associated with arrested forest recovery. How forest recovery is impeded in these areas remains poorly understood, especially in the African highlands. The component processes that can lead to recruitment limitation-including low seed arrival, availability and persistence-are important determinants of plant communities and offer a potential explanation for bracken persistence. We investigated key processes that can contribute to recruitment limitation in bracken-dominated clearings in the Bwindi Impenetrable National Park, Uganda...
April 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29700058/impact-of-female-sex-on-clinical-outcomes-in-the-fire-and-ice-trial-of-catheter-ablation-for-atrial-fibrillation
#5
Karl-Heinz Kuck, Josep Brugada, Alexander Fürnkranz, K R Julian Chun, Andreas Metzner, Feifan Ouyang, Michael Schlüter, Arif Elvan, Kendra M Braegelmann, Fred J Kueffer, Thomas Arentz, Jean-Paul Albenque, Michael Kühne, Christian Sticherling, Claudio Tondo
BACKGROUND: Data on predictors of long-term clinical outcomes after catheter ablation of atrial fibrillation (AF) are limited. We sought to assess the association of baseline covariates with clinical outcomes in the 750 patients with drug-refractory paroxysmal AF enrolled in FIRE AND ICE. METHODS: In a 2-part analysis, univariate and multivariable Cox regression models were first used to identify baseline patient characteristics predictive of catheter ablation efficacy determined by the clinical end points of (1) atrial arrhythmia recurrence (primary efficacy failure), (2) cardiovascular rehospitalization, and (3) repeat ablation...
May 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29694170/precision-measurement-of-the-e-e-%C3%A2-%C3%AE-_-c-%C3%AE-over-%C3%A2-_-c-cross-section-near-threshold
#6
M Ablikim, M N Achasov, S Ahmed, M Albrecht, M Alekseev, A Amoroso, F F An, Q An, J Z Bai, Y Bai, O Bakina, R Baldini Ferroli, Y Ban, K Begzsuren, D W Bennett, J V Bennett, N Berger, M Bertani, D Bettoni, F Bianchi, E Boger, I Boyko, R A Briere, H Cai, X Cai, O Cakir, A Calcaterra, G F Cao, S A Cetin, J Chai, J F Chang, G Chelkov, G Chen, H S Chen, J C Chen, M L Chen, P L Chen, S J Chen, X R Chen, Y B Chen, X K Chu, G Cibinetto, F Cossio, H L Dai, J P Dai, A Dbeyssi, D Dedovich, Z Y Deng, A Denig, I Denysenko, M Destefanis, F De Mori, Y Ding, C Dong, J Dong, L Y Dong, M Y Dong, Z L Dou, S X Du, P F Duan, J Fang, S S Fang, Y Fang, R Farinelli, L Fava, S Fegan, F Feldbauer, G Felici, C Q Feng, E Fioravanti, M Fritsch, C D Fu, Q Gao, X L Gao, Y Gao, Y G Gao, Z Gao, B Garillon, I Garzia, A Gilman, K Goetzen, L Gong, W X Gong, W Gradl, M Greco, M H Gu, Y T Gu, A Q Guo, R P Guo, Y P Guo, A Guskov, Z Haddadi, S Han, X Q Hao, F A Harris, K L He, X Q He, F H Heinsius, T Held, Y K Heng, T Holtmann, Z L Hou, H M Hu, J F Hu, T Hu, Y Hu, G S Huang, J S Huang, X T Huang, X Z Huang, Z L Huang, T Hussain, W Ikegami Andersson, Q Ji, Q P Ji, X B Ji, X L Ji, X S Jiang, X Y Jiang, J B Jiao, Z Jiao, D P Jin, S Jin, Y Jin, T Johansson, A Julin, N Kalantar-Nayestanaki, X S Kang, M Kavatsyuk, B C Ke, T Khan, A Khoukaz, P Kiese, R Kliemt, L Koch, O B Kolcu, B Kopf, M Kornicer, M Kuemmel, M Kuhlmann, A Kupsc, W Kühn, J S Lange, M Lara, P Larin, L Lavezzi, H Leithoff, C Li, Cheng Li, D M Li, F Li, F Y Li, G Li, H B Li, H J Li, J C Li, J W Li, Jin Li, K J Li, Kang Li, Ke Li, Lei Li, P L Li, P R Li, Q Y Li, W D Li, W G Li, X L Li, X N Li, X Q Li, Z B Li, H Liang, Y F Liang, Y T Liang, G R Liao, J Libby, C X Lin, D X Lin, B Liu, B J Liu, C X Liu, D Liu, F H Liu, Fang Liu, Feng Liu, H B Liu, H L Liu, H M Liu, Huanhuan Liu, Huihui Liu, J B Liu, J Y Liu, K Liu, K Y Liu, Ke Liu, L D Liu, Q Liu, S B Liu, X Liu, Y B Liu, Z A Liu, Zhiqing Liu, Y F Long, X C Lou, H J Lu, J G Lu, Y Lu, Y P Lu, C L Luo, M X Luo, X L Luo, S Lusso, X R Lyu, F C Ma, H L Ma, L L Ma, M M Ma, Q M Ma, T Ma, X N Ma, X Y Ma, Y M Ma, F E Maas, M Maggiora, Q A Malik, Y J Mao, Z P Mao, S Marcello, Z X Meng, J G Messchendorp, G Mezzadri, J Min, R E Mitchell, X H Mo, Y J Mo, C Morales Morales, N Yu Muchnoi, H Muramatsu, A Mustafa, Y Nefedov, F Nerling, I B Nikolaev, Z Ning, S Nisar, S L Niu, X Y Niu, S L Olsen, Q Ouyang, S Pacetti, Y Pan, M Papenbrock, P Patteri, M Pelizaeus, J Pellegrino, H P Peng, Z Y Peng, K Peters, J Pettersson, J L Ping, R G Ping, A Pitka, R Poling, V Prasad, H R Qi, M Qi, T Y Qi, S Qian, C F Qiao, N Qin, X S Qin, Z H Qin, J F Qiu, K H Rashid, C F Redmer, M Richter, M Ripka, M Rolo, G Rong, Ch Rosner, A Sarantsev, M Savrié, C Schnier, K Schoenning, W Shan, X Y Shan, M Shao, C P Shen, P X Shen, X Y Shen, H Y Sheng, X Shi, J J Song, W M Song, X Y Song, S Sosio, C Sowa, S Spataro, G X Sun, J F Sun, L Sun, S S Sun, X H Sun, Y J Sun, Y K Sun, Y Z Sun, Z J Sun, Z T Sun, Y T Tan, C J Tang, G Y Tang, X Tang, I Tapan, M Tiemens, B Tsednee, I Uman, G S Varner, B Wang, B L Wang, D Wang, D Y Wang, Dan Wang, K Wang, L L Wang, L S Wang, M Wang, Meng Wang, P Wang, P L Wang, W P Wang, X F Wang, Y Wang, Y D Wang, Y F Wang, Y Q Wang, Z Wang, Z G Wang, Z Y Wang, Zongyuan Wang, T Weber, D H Wei, J H Wei, P Weidenkaff, S P Wen, U Wiedner, M Wolke, L H Wu, L J Wu, Z Wu, L Xia, Y Xia, D Xiao, Y J Xiao, Z J Xiao, Y G Xie, Y H Xie, X A Xiong, Q L Xiu, G F Xu, J J Xu, L Xu, Q J Xu, Q N Xu, X P Xu, F Yan, L Yan, W B Yan, W C Yan, Y H Yan, H J Yang, H X Yang, L Yang, Y H Yang, Y X Yang, Yifan Yang, M Ye, M H Ye, J H Yin, Z Y You, B X Yu, C X Yu, J S Yu, C Z Yuan, Y Yuan, A Yuncu, A A Zafar, Y Zeng, Z Zeng, B X Zhang, B Y Zhang, C C Zhang, D H Zhang, H H Zhang, H Y Zhang, J Zhang, J L Zhang, J Q Zhang, J W Zhang, J Y Zhang, J Z Zhang, K Zhang, L Zhang, S Q Zhang, X Y Zhang, Y Zhang, Y H Zhang, Y T Zhang, Yang Zhang, Yao Zhang, Yu Zhang, Z H Zhang, Z P Zhang, Z Y Zhang, G Zhao, J W Zhao, J Y Zhao, J Z Zhao, Lei Zhao, Ling Zhao, M G Zhao, Q Zhao, S J Zhao, T C Zhao, Y B Zhao, Z G Zhao, A Zhemchugov, B Zheng, J P Zheng, Y H Zheng, B Zhong, L Zhou, Q Zhou, X Zhou, X K Zhou, X R Zhou, X Y Zhou, A N Zhu, J Zhu, K Zhu, K J Zhu, S Zhu, S H Zhu, X L Zhu, Y C Zhu, Y S Zhu, Z A Zhu, J Zhuang, B S Zou, J H Zou
The cross section of the e^{+}e^{-}→Λ_{c}^{+}Λ[over ¯]_{c}^{-} process is measured with unprecedented precision using data collected with the BESIII detector at sqrt[s]=4574.5, 4580.0, 4590.0 and 4599.5 MeV. The nonzero cross section near the Λ_{c}^{+}Λ[over ¯]_{c}^{-} production threshold is cleared. At center-of-mass energies sqrt[s]=4574.5 and 4599.5 MeV, the higher statistics data enable us to measure the Λ_{c} polar angle distributions. From these, the Λ_{c} electric over magnetic form-factor ratios (|G_{E}/G_{M}|) are measured for the first time...
March 30, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29691373/a-novel-sheet-like-virus-particle-array-is-a-hallmark-of-zika-virus-infection
#7
Jun Liu, Brandon A Kline, Tara A Kenny, Darci R Smith, Veronica Soloveva, Brett Beitzel, Song Pang, Stephen Lockett, Harald F Hess, Gustavo Palacios, Jens H Kuhn, Mei G Sun, Xiankun Zeng
Zika virus (ZIKV) is an emerging flavivirus that caused thousands of human infections in recent years. Compared to other human flaviviruses, ZIKV replication is not well understood. Using fluorescent, transmission electron, and focused ion beam-scanning electron microscopy, we examined ZIKV replication dynamics in Vero 76 cells and in the brains of infected laboratory mice. We observed the progressive development of a perinuclear flaviviral replication factory both in vitro and in vivo. In vitro, we illustrated the ZIKV lifecycle from particle cell entry to egress...
April 25, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29681254/dietary-resveratrol-impairs-body-weight-gain-due-to-reduction-of-feed-intake-without-affecting-fatty-acid-composition-in-atlantic-salmon
#8
D Menoyo, G Kühn, N Ruiz-Lopez, K Pallauf, I Stubhaug, J J Pastor, I R Ipharraguerre, G Rimbach
Recent studies suggest that the use of vegetable oils at expense of fish oil in aquaculture feeds might have potential negative effects on fish redox homeostasis and adiposity. Resveratrol (RESV) is a lipid-soluble phytoalexin present in fruits and vegetables with proven in vivo antioxidant function in animals. The present study aims to assess the potential use of RESV in Atlantic salmon feeds. To this end, post-smolt salmons with an initial BW of 148±3 g were fed four experimental diets for 15 weeks. A diet low in fish oil served as a control and was supplemented with 0, 0...
April 23, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29680923/taxonomy-of-the-family-arenaviridae-and-the-order-bunyavirales-update-2018
#9
Piet Maes, Sergey V Alkhovsky, Yīmíng Bào, Martin Beer, Monica Birkhead, Thomas Briese, Michael J Buchmeier, Charles H Calisher, Rémi N Charrel, Il Ryong Choi, Christopher S Clegg, Juan Carlos de la Torre, Eric Delwart, Joseph L DeRisi, Patrick L Di Bello, Francesco Di Serio, Michele Digiaro, Valerian V Dolja, Christian Drosten, Tobiasz Z Druciarek, Jiang Du, Hideki Ebihara, Toufic Elbeaino, Rose C Gergerich, Amethyst N Gillis, Jean-Paul J Gonzalez, Anne-Lise Haenni, Jussi Hepojoki, Udo Hetzel, Thiện Hồ, Ní Hóng, Rakesh K Jain, Petrus Jansen van Vuren, Qi Jin, Miranda Gilda Jonson, Sandra Junglen, Karen E Keller, Alan Kemp, Anja Kipar, Nikola O Kondov, Eugene V Koonin, Richard Kormelink, Yegor Korzyukov, Mart Krupovic, Amy J Lambert, Alma G Laney, Matthew LeBreton, Igor S Lukashevich, Marco Marklewitz, Wanda Markotter, Giovanni P Martelli, Robert R Martin, Nicole Mielke-Ehret, Hans-Peter Mühlbach, Beatriz Navarro, Terry Fei Fan Ng, Márcio Roberto Teixeira Nunes, Gustavo Palacios, Janusz T Pawęska, Clarence J Peters, Alexander Plyusnin, Sheli R Radoshitzky, Víctor Romanowski, Pertteli Salmenperä, Maria S Salvato, Hélène Sanfaçon, Takahide Sasaya, Connie Schmaljohn, Bradley S Schneider, Yukio Shirako, Stuart Siddell, Tarja A Sironen, Mark D Stenglein, Nadia Storm, Harikishan Sudini, Robert B Tesh, Ioannis E Tzanetakis, Mangala Uppala, Olli Vapalahti, Nikos Vasilakis, Peter J Walker, Guópíng Wáng, Lìpíng Wáng, Yànxiăng Wáng, Tàiyún Wèi, Michael R Wiley, Yuri I Wolf, Nathan D Wolfe, Zhìqiáng Wú, Wénxìng Xú, Li Yang, Zuòkūn Yāng, Shyi-Dong Yeh, Yǒng-Zhèn Zhāng, Yàzhōu Zhèng, Xueping Zhou, Chénxī Zhū, Florian Zirkel, Jens H Kuhn
In 2018, the family Arenaviridae was expanded by inclusion of 1 new genus and 5 novel species. At the same time, the recently established order Bunyavirales was expanded by 3 species. This article presents the updated taxonomy of the family Arenaviridae and the order Bunyavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV) and summarizes additional taxonomic proposals that may affect the order in the near future.
April 21, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29679775/influence-of-side-effects-on-early-therapy-persistence-with-letrozole-in-post-menopausal-patients-with-early-breast-cancer-results-of-the-prospective-evaluate-tm-study
#10
N Nabieva, T Fehm, L Häberle, J de Waal, M Rezai, B Baier, G Baake, H-C Kolberg, M Guggenberger, M Warm, N Harbeck, R Wuerstlein, J-U Deuker, P Dall, B Richter, G Wachsmann, C Brucker, J W Siebers, M Popovic, T Kuhn, C Wolf, H-W Vollert, G-P Breitbach, W Janni, R Landthaler, A Kohls, D Rezek, T Noesselt, G Fischer, S Henschen, T Praetz, V Heyl, T Kühn, T Krauss, C Thomssen, A Hohn, H Tesch, C Mundhenke, A Hein, C C Hack, K Schmidt, E Belleville, S Y Brucker, S Kümmel, M W Beckmann, D Wallwiener, P Hadji, P A Fasching
BACKGROUND: Endocrine treatment (ET) with an aromatase inhibitor (AI) is the treatment of choice in post-menopausal patients with hormone receptor-positive early breast cancer (EBC). However, adverse events (AEs) often lead to treatment discontinuation. This analysis aimed to identify side-effects that lead to patients failing to persist with letrozole treatment. PATIENTS AND METHODS: Post-menopausal hormone receptor-positive EBC patients starting ET with letrozole were enroled in EvAluate-TM, a non-interventional study...
April 18, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29674933/spind-an-r-package-to-account-for-spatial-autocorrelation-in-the-analysis-of-lattice-data
#11
Gudrun Carl, Sam C Levin, Ingolf Kühn
spind is an R package aiming to provide a useful toolkit to account for spatial dependence in the analysis of lattice data. Grid-based data sets in spatial modelling often exhibit spatial dependence, i.e. values sampled at nearby locations are more similar than those sampled further apart. spind methods, described here, take this kind of two-dimensional dependence into account and are sensitive to its variation across different spatial scales. Methods presented to account for spatial autocorrelation are based on the two fundamentally different approaches of generalised estimating equations as well as wavelet-revised methods...
2018: Biodiversity Data Journal
https://www.readbyqxmd.com/read/29667794/body-dysmorphic-disorder-in-the-cosmetic-practice
#12
Helena Kuhn, Paulo R Cunha, Natalie H Matthews, George Kroumpouzos
Body dysmorphic disorder (BDD) is a preoccupation with a slight or imagined flaw in appearance that causes significant distress and impairment in daily functioning. The disease is more prevalent among patients who seek aesthetic procedures as compared with population standards or individuals that are not interested in aesthetic surgery. Several studies have indicated that BDD symptoms typically worsen after an aesthetic procedure because the preoccupation shifts to a different body area. This article discusses the demographic and clinical features, psychiatric comorbidity, assessment, differential diagnosis, and management of BDD...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29659771/infectious-complications-after-deployment-trauma-following-wounded-united-states-military-personnel-into-veterans-affairs-care
#13
Jay R McDonald, Stephen Y Liang, Ping Li, Salwa Maalouf, Clinton K Murray, Amy C Weintrob, Elizabeth R Schnaubelt, Janis Kuhn, Anuradha Ganesan, William Bradley, David R Tribble
Background: Infectious complications related to deployment trauma significantly contribute to the morbidity and mortality impacting wounded service members. The Trauma Infectious Disease Outcomes Study (TIDOS) collects data on U.S. military personnel injured in Iraq and Afghanistan in an observational cohort study of infectious complications. Patients enrolled in TIDOS may also consent to follow-up through the Department of Veterans Affairs (VA). We present data from the first 337 TIDOS enrollees to receive VA healthcare...
April 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29656574/nmredata-a-standard-to-report-the-nmr-assignment-and-parameters-of-organic-compounds
#14
Marion Pupier, Jean-Marc Nuzillard, Julien Wist, Nils E Schlörer, Stefan Kuhn, Mate Erdelyi, Christoph Steinbeck, Antony J Williams, Craig Butts, Tim D W Claridge, Bozhana Mikhova, Wolfgang Robien, Hesam Dashti, Hamid R Eghbalnia, Christophe Farès, Christian Adam, Kessler Pavel, Fabrice Moriaud, Mikhail Elyashberg, Dimitris Argyropoulos, Manuel Pérez, Patrick Giraudeau, Roberto R Gil, Paul Trevorrow, Damien Jeannerat
Even though NMR has found countless applications in the field of small molecule characterization, there is no standard file format available for the NMR data relevant to structure characterization of small molecules. A new format is therefore introduced to associate the NMR parameters extracted from 1D and 2D spectra of organic compounds to the proposed chemical structure. These NMR parameters, which we shall call NMReDATA (for nuclear magnetic resonance extracted data), include chemical shift values, signal integrals, intensities, multiplicities, scalar coupling constants, lists of 2D correlations, relaxation times and diffusion rates...
April 14, 2018: Magnetic Resonance in Chemistry: MRC
https://www.readbyqxmd.com/read/29650408/normothermic-ex-vivo-preservation-with-the-portable-organ-care-system-lung-device-for-bilateral-lung-transplantation-inspire-a-randomised-open-label-non-inferiority-phase-3-study
#15
Gregor Warnecke, Dirk Van Raemdonck, Michael A Smith, Gilbert Massard, Jasleen Kukreja, Federico Rea, Gabriel Loor, Fabio De Robertis, Jayan Nagendran, Kumud K Dhital, Francisco Javier Moradiellos Díez, Christoph Knosalla, Christian A Bermudez, Steven Tsui, Kenneth McCurry, I-Wen Wang, Tobias Deuse, Guy Lesèche, Pascal Thomas, Igor Tudorache, Christian Kühn, Murat Avsar, Bettina Wiegmann, Wiebke Sommer, Arne Neyrinck, Marco Schiavon, Fiorella Calebrese, Nichola Santelmo, Anne Olland, Pierre-Emanuel Falcoz, Andre R Simon, Andres Varela, Joren C Madsen, Marshall Hertz, Axel Haverich, Abbas Ardehali
BACKGROUND: Severe primary graft dysfunction (PGD) of grade 3 (PGD3) is a common serious complication following lung transplantation. We aimed to assess physiological donor lung preservation using the Organ Care System (OCS) Lung device compared with cold static storage. METHODS: In this non-inferiority, randomised, controlled, open-label, phase 3 trial (INSPIRE) recipients were aged 18 years or older and were registered as standard criteria primary double lung transplant candidates...
April 9, 2018: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/29648866/a-spacing-account-of-negative-recency-in-final-free-recall
#16
Joel R Kuhn, Lynn J Lohnas, Michael J Kahana
The well-known recency effect in immediate free recall reverses when subjects attempt to recall items studied and tested on a series of prior lists, as in the final-free-recall procedure (Craik, 1970). In this case, the last few items on each list are actually remembered less well than are the midlist items. Because dual-store theories of recall naturally predict negative recency, this phenomenon has long been cited as evidence favoring these models. In a final-free-recall study, we replicate the negative-recency effect for the within-list serial position curve and the positive-recency effect for the between-list serial position curve...
April 12, 2018: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/29625616/the-role-of-ethnic-tourism-in-the-food-knowledge-tradition-of-tyrolean-migrants-in-treze-t%C3%A3-lias-sc-brazil
#17
Elisabeth Kuhn, Ruth Haselmair, Heidemarie Pirker, Christian R Vogl
BACKGROUND: Food knowledge and consumption in the context of migration is an important topic in ethnobiological research. Little research is done on the process of how external factors impact food knowledge amongst migrants. Taking into account social organisation and power relations of food knowledge transmission and distribution of food knowledge, this study sheds light on how the accessibility of resources, the predominant cuisine in the host country and ethnic tourism influences the food knowledge tradition of Tyrolean migrants and their descendants in Treze Tílias...
April 6, 2018: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29623447/decreased-bone-turnover-in-hiv-infected-children-on-antiretroviral-therapy
#18
Stephanie Shiau, Michael T Yin, Renate Strehlau, Faeezah Patel, Ndileka Mbete, Louise Kuhn, Ashraf Coovadia, Stephen M Arpadi
In this study, we evaluated the relationships between immune activation, bone turnover, and bone mass in virally suppressed HIV-infected children and HIV-uninfected children in South Africa. We found that decreased bone mass may occur or persist independent of immune activation and altered bone turnover. PURPOSE: HIV-infected children and adolescents have deficits in skeletal growth which include decreases in bone mass and alterations in bone microarchitecture. However, the mechanism by which HIV infection compromises bone accrual in children and adolescents is unclear...
April 5, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29618642/-ortervirales-a-new-viral-order-unifying-five-families-of-reverse-transcribing-viruses
#19
Mart Krupovic, Jonas Blomberg, John M Coffin, Indranil Dasgupta, Hung Fan, Andrew D Geering, Robert Gifford, Balázs Harrach, Roger Hull, Welkin Johnson, Jan F Kreuze, Dirk Lindemann, Carlos Llorens, Ben Lockhart, Jens Mayer, Emmanuelle Muller, Neil Olszewski, Hanu R Pappu, Mikhail Pooggin, Katja R Richert-Pöggeler, Sead Sabanadzovic, Hélène Sanfaçon, James E Schoelz, Susan Seal, Livia Stavolone, Jonathan P Stoye, Pierre-Yves Teycheney, Michael Tristem, Eugene V Koonin, Jens H Kuhn
Reverse-transcribing viruses, which synthesize a copy of genomic DNA from an RNA template, are widespread in animals, plants, algae and fungi (1, 2).….
April 4, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29608984/sorafenib-improves-alkylating-therapy-by-blocking-induced-inflammation-invasion-and-angiogenesis-in-breast-cancer-cells
#20
Alfeu Zanotto-Filho, Subapriya Rajamanickam, Eva Loranc, Pragathi Masamsetti, Aparna Gorthi, July Carolina Romero, Sonal Tonapi, Rosangela Mayer Gonçalves, Robert L Reddick, Raymond Benavides, John Kuhn, Yidong Chen, Alexander J R Bishop
Molecular targeted compounds are emerging as a strategy to improve classical chemotherapy. Herein, we describe that using low dose of the multikinase inhibitor sorafenib improves cyclophosphamide antitumor activity by inhibiting angiogenesis, metastasis and promoting tumor healing in MDA-MB231 xenografts and the 4T1-12B syngeneic breast cancer metastasis model. Mechanistic studies in MDA-MB231 cells revealed that alkylation upregulates inflammatory genes/proteins such as COX-2, IL8, CXCL2 and MMP1 in a MEK1/2-ERK1/2-dependent manner...
March 30, 2018: Cancer Letters
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