Yuting Lin, Shasha Liu, Yang Sun, Chen Chen, Songwei Yang, Gang Pei, Meiyu Lin, Jingbo Yu, Xuan Liu, Huiqin Wang, Junpeng Long, Qian Yan, Jinping Liang, Jiao Yao, Fan Yi, Lei Meng, Yong Tan, Naihong Chen, Yantao Yang, Qidi Ai
Chemokines and their corresponding receptors play crucial roles in orchestrating inflammatory and immune responses, particularly in the context of pathological conditions disrupting the internal environment. Among these receptors, CCR5 has garnered considerable attention due to its significant involvement in the inflammatory cascade, serving as a pivotal mediator of neuroinflammation and other inflammatory pathways associated with various diseases. However, a notable gap persists in comprehending the intricate mechanisms governing the interplay between CCR5 and its ligands across diverse and intricate inflammatory pathologies...
March 30, 2024: Ageing Research Reviews