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https://www.readbyqxmd.com/read/28527091/raven-coloured-progressive-matrices-in-migraine-without-aura-patients
#1
Giovanna Viticchi, Lorenzo Falsetti, Marco Bartolini, Laura Buratti, Lara Pistelli, Leandro Provinciali, Mauro Silvestrini
Conflicting results emerged from studies investigating cognitive performances in migraine patients. Based on clinical and neuroradiological aspects, the possible involvement of executive functions has been especially taken into consideration. The aim of this study was to evaluate, in a population of subjects affected by migraine without aura (MwoA), frontal lobe cognitive functions. We enrolled all the consecutive patients affected by MwoA referred to our headache centre for a first evaluation. Each patient underwent a neuropsychological evaluation including Raven coloured progressive matrices (CPM)...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527066/community-pharmacies-as-epidemiological-sentinels-of-headache-first-experience-in-italy
#2
Paola Brusa, Marco Parente, Gianni Allais, Sara Rolando, Giuseppe Costa, Roberto Gnavi, Teresa Spadea, Mario Giaccone, Andrea Mandelli, Massimo Mana, Francesca Baratta, Chiara Benedetto, Gennaro Bussone
Migraine is a disabling neurovascular syndrome which affects 12-15% of the global population and it represents the third cause in years lived with disability in both males and females aged 15-49 years. Among migraineurs, the symptomatic drug abuse may be a risk factor in the development of medication overuse headache (MOH). Detecting cases of MOH is not straightforward; community pharmacists may, therefore, be in a strategic position to identify individuals who self-medicate, particularly with respect to prevent the development of MOH...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527032/methylone-and-mdpv-activate-autophagy-in-human-dopaminergic-sh-sy5y-cells-a-new-insight-into-the-context-of-%C3%AE-keto-amphetamines-related-neurotoxicity
#3
Maria João Valente, Cristina Amaral, Georgina Correia-da-Silva, José Alberto Duarte, Maria de Lourdes Bastos, Félix Carvalho, Paula Guedes de Pinho, Márcia Carvalho
Autophagy has an essential role in neuronal homeostasis and its dysregulation has been recently linked to neurotoxic effects of a growing list of psychoactive drugs, including amphetamines. However, the role of autophagy in β-keto amphetamine (β-KA) designer drugs-induced neurotoxicity has hitherto not been investigated. In the present study, we show that two commonly abused cathinone derivatives, 3,4-methylenedioxymethcathinone (methylone) and 3,4-methylenedioxypyrovalerone (MDPV), elicit morphological changes consistent with autophagy and neurodegeneration, including formation of autophagic vacuoles and neurite retraction in dopaminergic SH-SY5Y cells...
May 19, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28526662/attachment-style-and-internet-addiction-an-online-survey
#4
Christiane Eichenberg, Markus Schott, Oliver Decker, Brigitte Sindelar
BACKGROUND: One of the clinically relevant problems of Internet use is the phenomenon of Internet addiction. Considering the fact that there is ample evidence for the relationship between attachment style and substance abuse, it stands to reason that attachment theory can also make an important contribution to the understanding of the pathogenesis of Internet addiction. OBJECTIVE: The aim of this study was to examine people's tendency toward pathological Internet usage in relation to their attachment style...
May 17, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28526631/mating-strategies-and-sexual-functioning-in-personality-disorders-a%C3%A2-comprehensive-review-of-literature
#5
REVIEW
Alberto Collazzoni, Giacomo Ciocca, Erika Limoncin, Carmela Marucci, Daniele Mollaioli, Stefania Di Sante, Giorgio Di Lorenzo, Cinzia Niolu, Alberto Siracusano, Mario Maggi, Giovanni Castellini, Alessandro Rossi, Emmanuele A Jannini
INTRODUCTION: Personality disorders impair several aspects of intrapsychic and interpersonal life. In particular, mating strategies and sexual functioning could manifest in different and/or dysfunctional ways in people with personality disorders. AIM: To describe, through a comprehensive review of the literature, the mating strategies and sexual functioning in patients with personality disorders. METHODS: We listed and discussed the principal studies on the relation between mating strategies and sexual functioning in personality disorders...
May 16, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28526550/impact-of-first-eye-versus-second-eye-cataract-surgery-on-visual-function-and-quality-of-life
#6
Nakul S Shekhawat, Michael V Stock, Elizabeth F Baze, Mary K Daly, David E Vollman, Mary G Lawrence, Amy S Chomsky
PURPOSE: To compare the impact of first eye versus second eye cataract surgery on visual function and quality of life. DESIGN: Cohort study. PARTICIPANTS: A total of 328 patients undergoing separate first eye and second eye phacoemulsification cataract surgeries at 5 veterans affairs centers in the United States. Patients with previous ocular surgery, postoperative endophthalmitis, postoperative retinal detachment, reoperation within 30 days, dementia, anxiety disorder, hearing difficulty, or history of drug abuse were excluded...
May 16, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28525876/discrete-category-of-mother-to-infant-bonding-disorder-and-its-identification-by-the-mother-to-infant-bonding-scale-a-study-in-japanese-mothers-of-a-1-month-old
#7
Asami Matsunaga, Fumie Takauma, Katsuhiko Tada, Toshinori Kitamura
BACKGROUND: Difficulty of maternal bonding towards a baby is widely recognised. It is unclear whether this phenomenon is dimensional or categorical. If categorical, an optimal cut-off score of a screening instrument is needed in clinical settings. AIMS: In this study, we investigated whether maternal bonding is dimensional or categorical phenomenon and try to set optimal cut-off score of screening instruments. METHODS: Self-report questionnaire studies were conducted in a general hospital and four antenatal clinics...
May 16, 2017: Early Human Development
https://www.readbyqxmd.com/read/28525788/psychosocial-relationship-status-and-quality-as-predictors-of-exercise-intervention-adherence-and-substance-use-outcomes-results-from-the-stride-ctn-0037-study
#8
Joseph M Trombello, Thomas Carmody, Tracy L Greer, Robrina Walker, Chad D Rethorst, Madhukar H Trivedi
Social/intimate relationship status and quality are associated with health-promoting behaviors, while living alone or being isolated are adversely associated with physical and mental health outcomes. Limited work has investigated how particular components of one's social environment - usual living arrangements, satisfaction with those arrangements, and global social and family discord - are related to substance use reduction and intervention adherence. We investigated these questions in 270 individuals receiving study intervention for stimulant abuse/dependence through the multi-site Stimulant Reduction Intervention using Dosed Exercise (CTN-0037) trial...
April 28, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28525721/development-and-application-of-a-screening-method-of-absolute-qpcr-to-detect-the-abuse-of-sex-steroid-hormone-administration-in-male-bovine
#9
Laura Starvaggi Cuccuzza, Bartolomeo Biolatti, Sara Divari, Paola Pregel, Frine E Scaglione, Alessandra Sereno, Francesca T Cannizzo
A method for absolute quantification of regucalcin gene by quantitative PCR was developed to confirm that the decrease of regucalcin gene expression in the testis is a valid biomarker for detection of sex steroid hormone treatment in bovine husbandry. An external standard curve was developed with TaqMan technology. Based on in vivo experiments, specificity, sensitivity and criterion value of this potential biomarker were calculated by means of a ROC curve. Then, regucalcin gene expression was evaluated in beef and veal calves for human consumption...
May 19, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28525611/adverse-childhood-experiences-and-higher-level-functional-limitations-among-older-japanese-people-results-from-the-jages-study
#10
Airi Amemiya, Takeo Fujiwara, Hiroshi Murayama, Yukako Tani, Katsunori Kondo
Background.: A life-course perspective is essential in understanding the determinants of higher-level functional limitations. We examine the impact of adverse childhood experiences (ACEs) on higher-level functional limitations in older people. Methods.: Data were from the Japan Gerontological Evaluation Study 2013, a population-based cohort of independent people aged 65 years or older across Japan (n = 19,220). ACEs before the age of 18 were assessed in terms of seven adversities: parental death, parental divorce, parental mental illness, family violence, physical abuse, psychological neglect, and psychological abuse...
May 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28525559/first-onset-mental-disorders-after-cancer-diagnosis-and-cancer-specific-mortality-a-nationwide-cohort-study
#11
J Zhu, F Fang, A Sjölander, K Fall, H O Adami, U Valdimarsdóttir
BACKGROUND: The diagnosis of cancer is strongly associated with the risk of mental disorders even in patients with no previous history of mental disorders. Accumulating data suggest that mental distress may accelerate tumor progression. We hypothesized therefore that mental disorders after a cancer diagnosis may increase the risk of cancer-specific mortality. PATIENTS AND METHODS: We conducted a nationwide cohort study including 244,261 cancer patients diagnosed in Sweden during 2004-2009 and followed them through 2010...
May 19, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28525320/sexual-and-reproductive-health-priorities-of-adolescent-girls-in-lagos-nigeria-findings-from-free-listing-interviews
#12
Juliet Iwelunmor, Sarah Blackstone, Ucheoma Nwaozuru, Donaldson Conserve, Patricia Iwelunmor, John E Ehiri
Background Adolescent girls in Nigeria experience a disproportionately high burden of sexual and reproductive health disparities that affect their well-being. Yet, little is known about adolescent girls' own unique perspectives of the sexual and reproductive health challenges they face, and possible solutions to these challenges. Aims To explore top sexual and reproductive health concerns of female adolescents in Nigeria and their perceptions regarding potential solutions to these issues. Methods Eighty adolescent girls attending two public secondary schools in Lagos, Nigeria completed individual free-listing interviews...
May 17, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28525249/-a-less-known-cause-of-incoercible-vomiting
#13
S Guyoundouzian, R Attou, P Guérisse, T Préseau
Cannabis is a widely spread drug which chronic abuse may cause diverse adverse effects on the body, in the short and long term. Among these effects, we can cite digestive disorders, mainly characterized by the onset of cyclical vomiting illness. Vomiting symptoms can be temporarily relieved by hot water showers. As a matter of fact, many patients adopt a compulsive bathing behavior characterized by the irrepressible need of having showers or baths at a high temperature. We describe the case of two patients (22 and 23 years-old) who consume cannabis on a regular basis...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28524806/racial-and-ethnic-differences-in-treatment-outcomes-among-adults-with-stimulant-use-disorders-after-a-dosed-exercise-intervention
#14
K Sanchez, T L Greer, R Walker, T Carmody, C D Rethorst, M H Trivedi
The current study examined differences in substance abuse treatment outcomes among racial and ethnic groups enrolled in the Stimulant Reduction Intervention using Dosed Exercise (STRIDE) trial, a multisite randomized clinical trial implemented through the National Institute on Drug Abuse's (NIDA's) Clinical Trials Network (CTN). STRIDE aimed to test vigorous exercise as a novel approach to the treatment of stimulant abuse compared to a health education intervention. A hurdle model with a complier average causal effects (CACE) adjustment was used to provide an unbiased estimate of the exercise effect had all participants been adherent to exercise...
May 19, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/28524758/seeking-safety-group-therapy-for-co-occurring-substance-use-disorder-and-ptsd-among-transgender-women-living-with-hiv-a-pilot-study
#15
Susannah Empson, Yvette P Cuca, Jennifer Cocohoba, Carol Dawson-Rose, Katy Davis, Edward L Machtinger
Transgender women living with HIV experience high rates of substance use, violence, and post-traumatic stress disorder (PTSD). Seeking Safety is a manualized, present-focused, cognitive-behavioral therapy program designed to address co-occurring substance use and PTSD. Seeking Safety has evidence of efficacy in a variety of populations but had not been evaluated specifically with people living with HIV or transgender women. We pilot-tested a 12-session Seeking Safety program with a group of transgender women living with HIV who reported substance use and a history of violence...
May 19, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28524713/usual-alcohol-consumption-and-risks-for-nonfatal-fall-injuries-in-the-united-states-results-from-the-2004-2013-national-health-interview-survey
#16
Chiung M Chen, Young-Hee Yoon
BACKGROUND: Acute alcohol consumption is known to be a risk factor for fall injuries. OBJECTIVE: The study sought to determine whether usual alcohol consumption increases the risk for nonfatal fall injuries. METHOD: Data from 289,187 sample adults in the 2004-2013 U.S. National Health Interview Surveys were analyzed. Of these, 3,368 (∼1%) reported a total of 3,579 fall-injury episodes requiring medical consultation in the past 3 months...
May 19, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28524260/presence-of-ethanol-sensitive-glycine-receptors-in-medium-spiny-neurons-in-the-mouse-nucleus-accumbens
#17
B Förstera, B Muñoz, M K Lobo, R Chandra, D M Lovinger, L G Aguayo
Alcohol abuse causes major social, economic and health-related problems worldwide. Alcohol, like other drugs of abuse, increases levels of dopamine in the nucleus accumbens, facilitating behavioural reinforcement and substance abuse. Previous studies suggested that glycine receptors (GlyRs) are involved in the regulation of accumbal dopamine levels. Here, we investigated the presence of GlyRs in accumbal dopamine receptor medium spiny neurons (MSNs) of C57BL/6J mice, analyzing mRNA expression-levels and immunoreactivity of GlyR subunits, as well as ethanol sensitivity...
May 19, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28523944/commercial-sexual-behaviors-among-male-rural-to-urban-migrants-in-western-china-implications-for-hiv-prevention
#18
Wenwei Li, Junjun Jiang, Jinming Su, Bingyu Liang, Wei Deng, Jiegang Huang, Bo Qin, Halmurat Upur, Chaohui Zhong, Qianqiu Wang, Qian Wang, Ning Zang, Yanyan Liao, Sirun Meng, Li Ye, Hao Liang
Rural-to-urban migrants are at high risk of HIV infection. The goal of this survey was to explore the commercial sexual behavior and condom use among male rural-to-urban migrants in western China. A cross-sectional survey on male rural-to-urban migrants in western China was conducted. Among all the subjects surveyed, 140 (7.4%) had commercial sexual behavior, which is associated with being aged older than 24 years, being of Han or other ethnic minorities, being divorced, separated, or widowed, having experienced drug abuse, having had heterosexual behavior, having had casual sexual partners, having had sex with a homosexual, and being from Xinjiang...
May 1, 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28523735/variability-in-prescription-opioid-intake-and-reinforcement-amongst-129-substrains
#19
Susan M Jimenez, Aiden F Healy, Michal A Coelho, Chelsea N Brown, Tod E Kippin, Karen K Szumlinski
Opioid abuse in the United States has reached epidemic proportions, with treatment admissions and deaths associated with prescription opioid abuse quadrupling over the past 10 years. Although genetics are theorized to contribute substantially to inter-individual variability in the development, severity, and treatment outcomes of opioid abuse/addiction, little direct preclinical study has focused on the behavioral genetics of prescription opioid reinforcement and drug-taking. Herein, we employed different 129 substrains of mice currently available from The Jackson Laboratory (129S1/SvlmJ, 129X1/SvJ, 129S4/SvJaeJ and 129P3/J) as a model system of genetic variation and assayed mice for oral opioid intake and reinforcement, as well as behavioral and somatic signs of dependence...
May 19, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28523545/anxiety-and-epigenetics
#20
Andrew A Bartlett, Rumani Singh, Richard G Hunter
Anxiety disorders are highly prevalent psychiatric disorders often comorbid with depression and substance abuse. Twin studies have shown that anxiety disorders are moderately heritable. Yet, genome-wide association studies (GWASs) have failed to identify gene(s) significantly associated with diagnosis suggesting a strong role for environmental factors and the epigenome. A number of anxiety disorder subtypes are considered "stress related." A large focus of research has been on the epigenetic and anxiety-like behavioral consequences of stress...
2017: Advances in Experimental Medicine and Biology
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