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https://www.readbyqxmd.com/read/28081567/risk-of-rebleeding-and-mortality-in-cirrhotic-patients-with-peptic-ulcer-bleeding-a-12-year-nationwide-cohort-study
#1
Shih-Cheng Yang, Chien-Ning Hsu, Chih-Ming Liang, Wei-Chen Tai, Cheng-Kun Wu, Chih-Wei Shih, Ming-Kun Ku, Lan-Ting Yuan, Jiunn-Wei Wang, Kuo-Lun Tseng, Tsung-Hsing Hung, Seng-Howe Nguang, Pin-I Hsu, Deng-Chyang Wu, Seng-Kee Chuah
Although a few studies have investigated the risks of peptic ulcer bleeding (PUB) in cirrhotic patients, large population-based studies on in-hospital and long-term reports on recurrent PUB in a cohort of cirrhotic patients are lacking. This 12-year nationwide cohort study aimed to investigate the risks of in-hospital and long-term rebleeding and mortality in cirrhotic patients and to identify possible risk factors. Patient data from 1997 to 2008 were extracted from the National Health Insurance Research Database in Taiwan...
2017: PloS One
https://www.readbyqxmd.com/read/28077930/before-the-freeze-otoliths-from-the-eocene-of-seymour-island-antarctica-reveal-dominance-of-gadiform-fishes-teleostei
#2
Werner Schwarzhans, Thomas Mörs, Andrea Engelbrecht, Marcelo Reguero, Jürgen Kriwet
The first record of fossil teleostean otoliths from Antarctica is reported. The fossils were obtained from late Early Eocene shell beds of the La Meseta Formation, Seymour Island that represent the last temperate marine climate phase in Antarctica prior to the onset of cooling and subsequent glaciation during the late Eocene. A total of 17 otolith-based teleost taxa are recognized, with 10 being identifiable to species level containing nine new species and one new genus: Argentina antarctica sp. nov., Diaphus? marambionis sp...
2017: Journal of Systematic Palaeontology
https://www.readbyqxmd.com/read/28077318/alcohol-microbiome-life-style-influence-alcohol-and-non-alcoholic-organ-damage
#3
REVIEW
Manuela G Neuman, Samuel W French, Samir Zakhari, Stefen Malnick, Helmut K Seitz, Lawrence B Cohen, Mikko Salaspuro, Andreea Voinea Griffin, Andrei Barasch, Irina A Kirpich, Paul G Thomes, Laura W Schrum, Terrence M Donohue, Kusum Kharbanda, Marcus Cruz, Mihai Opris
This paper is based upon the "8th Charles Lieber's Satellite Symposium" organized by Manuela G. Neuman at the Research Society on Alcoholism Annual Meeting, onJune 25, 2016 at New Orleans, Louisiana, USA. The integrative symposium investigated different aspects of alcohol-induced liver disease (ALD) as well as non-alcohol-induced liver disease (NAFLD) and possible repair. We revealedthe basic aspects of alcohol metabolism that may be responsible for the development of liver diseaseas well as the factors that determine the amount, frequency and which type of alcohol misuse leads to liver and gastrointestinal diseases...
January 7, 2017: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/28077082/the-arabidopsis-paralogs-pub46-and-pub48-encoding-u-box-e3-ubiquitin-ligases-are-essential-for-plant-response-to-drought-stress
#4
Guy Adler, Zvia Konrad, Lyad Zamir, Amit Kumar Mishra, Dina Raveh, Dudy Bar-Zvi
BACKGROUND: Plants respond to abiotic stress on physiological, biochemical and molecular levels. This includes a global change in their cellular proteome achieved by changes in the pattern of their protein synthesis and degradation. The ubiquitin-proteasome system (UPS) is a key player in protein degradation in eukaryotes. Proteins are marked for degradation by the proteasome by coupling short chains of ubiquitin polypeptides in a three-step pathway. The last and regulatory stage is catalyzed by a member of a large family of substrate-specific ubiquitin ligases...
January 11, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28062899/bibi-ergo-sum-the-effects-of-a-placebo-and-contextual-alcohol-cues-on-motivation-to-drink-alcohol
#5
Paul Christiansen, Gareth Townsend, Graeme Knibb, Matt Field
RATIONALE: Acute 'priming' doses of alcohol reliably increase alcohol-seeking behaviour in social drinkers. However, the effects of the anticipated (rather than pharmacological) effects of alcohol, and their interaction with contextual alcohol cues, are not well understood. OBJECTIVES: This study aims to determine the extent to which an alcohol-placebo drink increases craving, subjective intoxication and beer consumption, while conjointly investigating the impact of contextual alcohol cues...
January 7, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28053163/atgc-database-and-atgc-cogs-an-updated-resource-for-micro-and-macro-evolutionary-studies-of-prokaryotic-genomes-and-protein-family-annotation
#6
David M Kristensen, Yuri I Wolf, Eugene V Koonin
The Alignable Tight Genomic Clusters (ATGCs) database is a collection of closely related bacterial and archaeal genomes that provides several tools to aid research into evolutionary processes in the microbial world. Each ATGC is a taxonomy-independent cluster of 2 or more completely sequenced genomes that meet the objective criteria of a high degree of local gene order (synteny) and a small number of synonymous substitutions in the protein-coding genes. As such, each ATGC is suited for analysis of microevolutionary variations within a cohesive group of organisms (e...
January 4, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28039816/overexpression-of-a-stress-responsive-u-box-protein-gene-vapub-affects-the-accumulation-of-resistance-related-proteins-in-vitis-vinifera-thompson-seedless
#7
Li Jiao, Yali Zhang, Jiang Lu
Many U-box proteins have been identified and characterized as important factors against environmental stresses such as chilling, heat, salinity and pathogen attack in plant. Our previous research reported the cloning of a novel U-box protein gene VaPUB from Vitis amurensis 'Zuoshanyi' grape and suggested a function of it in related to cold stress in the model plant Arabidopsis system. In this study, the role of VaPUB in response to biotic and abiotic stress was further analyzed in the homologous grapevine system by studying the transcript regulation and the protein accumulation in VaPUB transgenic vines...
December 25, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28002906/tears-of-popliteomeniscal-fascicles-diagnostic-and-clinical-implications-a-review-of-the-evidence
#8
R Papalia, R Simonetta, G Di Vico, G Torre, L Saccone, J Espregueira-Mendes, V Denaro
Postero-lateral corner of the knee is composed of several structures including the popliteo-meniscal fascicles (PMFs). These fibrous structures form a stable ligamentous complex around the popliteus tendon, which stabilize the lateral meniscus, increasing the strength of postero-lateral corner. Studies were retrieved through an electronic search of CINAHL, EMBASE, and Pub-Med, until May 2016. Studies in English, Italian, French, and Spanish were considered for inclusion. Randomized controlled trials, prospective and retrospective comparative studies, case series, and case reports were included...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27999640/toxoplasmosis-in-iran-a-guide-for-general-physicians-working-in-the-iranian-health-network-setting-a-systematic-review
#9
REVIEW
Seyed Mohammad Alavi, Leila Alavi
BACKGROUND: Human toxoplasmosis is an important zoonotic infection worldwide which is caused by the intracellular parasite Toxoplasma gondii (T.gondii). The aim of this study was to review briefly the general aspects of toxoplasma infection in in Iranian health system network. METHODS: We searched published toxoplasmosis related articles in English databases including Science Direct, Pub Med, Scopus, Google Scholar, Magiran, Iran Medex, Iran Doc and Scientific Information Database (SID) for toxoplasmosis...
2016: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/27986866/extra-large-g-proteins-interact-with-e3-ligases-pub4-and-pub2-and-function-in-cytokinin-and-developmental-processes
#10
Yiping Wang, Yingying Wu, Boying Yu, Zhao Yin, Yiji Xia
Heterotrimeric GTP-binding proteins (G proteins) composed of Gα, Gβ, and Gγ subunits are conserved signal transduction molecules in animals and plants. In Arabidopsis there are three Gα-like proteins named extra-large G proteins (XLGs) in addition to the canonical Gα protein GPA1. XLGs have been reported to be implicated in multiple pathways although the underlying mechanisms of their action remain elusive. Here, we report that all three XLGs interact with two closely related plant U-box (PUB) E3 ligases, PUB2 and PUB4...
December 16, 2016: Plant Physiology
https://www.readbyqxmd.com/read/27986646/investigation-of-the-association-between-alcohol-outlet-density-and-alcohol-related-hospital-admission-rates-in-england-study-protocol
#11
Ravi Maheswaran, John Holmes, Mark Green, Mark Strong, Tim Pearson, Petra Meier
BACKGROUND: Availability of alcohol is a major policy issue for governments, and one of the availability factors is the density of alcohol outlets within geographic areas. OBJECTIVE: The aim of this study is to investigate the association between alcohol outlet density and hospital admissions for alcohol-related conditions in a national (English) small area level ecological study. METHODS: This project will employ ecological correlation and cross-sectional time series study designs to examine spatial and temporal relationships between alcohol outlet density and hospital admissions...
December 16, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27967827/prejudice-in-the-pub-how-alcohol-and-ideology-loosen-the-tongue
#12
Masi Noor, Hanna Reed, Bertjan Doosje
This study (N = 124) tested the main and interactive effects of alcohol consumption, egalitarianism and right wing authoritarianism (RWA) in relation to prejudice suppression in the natural environment of a British Public House (pub). Employing a quasi-experimental between-subjects design, participants who had consumed alcohol were worse at suppressing their prejudice than participants with no alcohol consumption. Further, the more participants endorsed egalitarian values, the more they were able to suppress their prejudice...
December 14, 2016: Journal of Social Psychology
https://www.readbyqxmd.com/read/27943551/a-systematic-review-of-dyadic-studies-examining-relationship-quality-incouples-facing-colorectal-cancer-together
#13
REVIEW
Chiara Acquati, Jennifer Barsky Reese, Eli Karam, Karen Kayser, Kristen Mark, Daniela Wittmann
BACKGROUND: Despite the adverse effects that treatment for colorectal cancer can have on patients' quality of life and, in particular, their intimate relationships, very little research has been conducted on the psychosocial adjustment for both patients and their partners/spouses. OBJECTIVES: The aim of this systematic review was to examine dyadic studies of adjustment in couples in which one partner has been diagnosed with colorectal cancer. METHODS: Pub Med, PsychINFO, MEDLINE, Social Sciences Abstracts (EBSCO) and the Cochrane Library were systematically searched for studies reporting quality of life outcomes for colorectal cancer patients and their partners/spouses...
December 10, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27938698/treatment-of-select-intrabony-defects-by-periodontal-regeneration-could-be-cost-effective-long-term-in-compliant-patients
#14
Satheesh Elangovan
Periodontal regeneration compared with access flap surgery in human intrabony defects: 20-year follow-up of a randomized clinical trial: tooth regeneration, periodontitis recurrence and costs. Cortellini P, Buti J, Prato GP, Tonetti MS.J Clin Periodontolhttp://dx.doi.org/10.1111/jcpe.12638 [Pre pub/accepted manuscript] SOURCE OF FUNDING: Nonprofit, foundations: European Research Group on Periodontology, Genova, Italy; other: Accademia Toscana di Ricerca Odontostomatologica, Florence, Italy TYPE OF STUDY/DESIGN: Randomized controlled trial...
December 2016: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/27938537/uncommon-localizations-of-hydatid-cyst-review-of-the-literature
#15
G Salamone, L Licari, B Randisi, N Falco, R Tutino, A Vaglica, R Gullo, C Porello, G Cocorullo, G Gulotta
INTRODUCTION: Hydatid disease is an endemic anthropozoonosis with usual localization in liver and lungs. Rarely it localizes in uncommon sites as spleen, skeleton, kidney, brain, cardiac muscle, peritoneum, sub cutis. Complications of uncommon localizations are the same that for usual ones. MATERIAL AND METHODS: Review of the literature on rare and atypical localization of hydatid cysts in soft tissues. Key-words used on Pub-Med [(echinococ OR hydatid) AND (soft tissue OR subcutaneous OR cutaneous)] without time limit...
July 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27936971/drug-reaction-with-eosinophilia-and-systemic-symptoms-dress-incidence-pathogenesis-and-management
#16
Tetsuo Shiohara, Yoko Kano
Drug-induced hypersensitivity syndrome(DiHS), often referred to as drug reaction with eosinophilia and systemic symptoms (DRESS), is a life-threatening multi-organ system reaction induced by drugs and associated with sequential reactivations of herpesviruses. This syndrome has several unique features, creating uncertainty over whether it represents true drug eruption. Areas covered: A literature review of all the cases was made by a Pub Med search. The delayed onset, paradoxical worsening of clinical symptoms after withdrawal of the causative drug and unexplained cross-reactivity to multiple drugs are unique features of this syndrome, which could prompt infection to be an initial consideration...
December 21, 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/27931138/medicinal-plants-and-natural-products-in-amelioration-of-arsenic-toxicity-a-short-review
#17
Sanijb Bhattacharya
CONTEXT: Chronic arsenic toxicity (arsenicosis) is considered a serious public health menace worldwide, as there is no specific, safe, and efficacious therapeutic management of arsenicosis. OBJECTIVES: To collate the studies on medicinal plants and natural products with arsenic toxicity ameliorative effect, active pre-clinically and/or clinically. METHODS: Literature survey was carried out by using Google, Scholar Google and Pub-Med. Only the scientific journal articles found on the internet for last two decades were considered...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27930921/nursing-students-attitudes-toward-persons-who-are-aged-an-integrative-review
#18
REVIEW
Susan Hovey, Mary J Dyck, Cynthia Reese, MyoungJin Kim
OBJECTIVES: To analyze empirical studies from the United States and Canada to gain an understanding on how nursing education affects nursing students' attitudes toward persons who are aged. DESIGN: An integrative literature review was completed using Garrard's (2011) Matrix Method. DATA SOURCES: Articles were identified through the electronic database search engines of CINAHL, Pub Med, and Academic Search Complete. Only peer reviewed research articles from 2009 to 2015 were reviewed...
February 2017: Nurse Education Today
https://www.readbyqxmd.com/read/27918221/neutrophilic-inflammation-in-asthma-mechanisms-and-therapeutic-considerations
#19
Hun Soo Chang, Tae-Hyeong Lee, Ji Ae Jun, Ae Rin Baek, Jong-Sook Park, So-My Koo, Yang-Ki Kim, Ho Sung Lee, Choon-Sik Park
Neutrophilic airway inflammation represents a pathologically distinct form of asthma and frequently appears in symptomatic adulthood asthmatics. However, clinical impacts and mechanisms of the neutrophilic inflammation have not been thoroughly evaluated up to date. Areas covered: Currently, distinct clinical manifestations, triggers, and molecular mechanisms of the neutrophilic inflammation (namely Toll-like receptor, Th1, Th17, inflammasome) are under investigation in asthma. Furthermore, possible role of the neutrophilic inflammation is being investigated in respect to the airway remodeling...
January 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/27891491/mri-in-dentistry-a-future-towards-radiation-free-imaging-systematic-review
#20
REVIEW
Lav Kumar Niraj, Basavaraj Patthi, Ashish Singla, Ritu Gupta, Irfan Ali, Kuldeep Dhama, Jishnu Krishna Kumar, Monika Prasad
INTRODUCTION: Magnetic Resonance Imaging (MRI), being a technique with huge potential, has become the primary diagnostic investigation for many clinical problems. Its application now has been successfully used in dentistry to maximize the diagnostic certainty. AIM: The present review aims to analyze the applicability, feasibility and efficacy of MRI in the field of dentistry. MATERIALS AND METHODS: A literature search was performed in main databases like Pub Med Central, Cochrane Library, Embase and Google Scholar from 1970 up to December 2015...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
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