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https://www.readbyqxmd.com/read/29156842/associations-between-egfr-gene-polymorphisms-and-susceptibility-to-glioma-a-systematic-review-and-meta-analysis-from-gwas-and-case-control-studies
#1
Xiao Yu, Nian Rong Sun, Hai Tao Jang, Shi Wen Guo, Min Xue Lian
The results of genome-wide association studies (GWAS) and case-control studies performed to investigate the associations between epidermal growth factor receptor (EGFR) gene polymorphisms and glioma risk are controversial. The aim of this systematic review and meta-analysis is to determine whether EGFR gene polymorphisms are associated with glioma risk by searching 'PubMed', 'EMBASE', 'Web of Science', 'Cochrane Library' and 'China WeiPu Library' to retrieve studies that investigated associations between EGFR gene polymorphisms and glioma risk...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29156837/meta-analysis-of-efficacy-and-adverse-events-of-erlotinib-based-targeted-therapies-for-advanced-metastatic-non-small-cell-lung-cancer
#2
Fei Li, Shu-Hua Zhang, Li-Min Pang
A network meta-analysis evaluating efficacy and adverse events of eight erlotinib-based therapies (erlotinib+placebo, erlotinib+tivantinib, erlotinib+celecoxib, erlotinib+onartuzumab, erlotinib+sunitinib, erlotinib+entinostat, erlotinib+sorafenib, and erlotinib+bevacizumab) for advanced/metastatic non-small-cell lung cancer (NSCLC) was performed. PubMed and Cochrane Library were reviewed, and ten randomized controlled trials were identified in which patients receiving at least one erlotinib-based therapy. Efficacy outcomes, including progression-free survival (PFS), overall survival (OS), overall response rate (ORR), disease control rate (DCR), and adverse outcomes were evaluated...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29155520/high-expression-level-of-long-non-coding-rna-hotair-is-associated-with-poor-overall-survival-in-gastric-cancer-patients-evidence-from-meta-analysis
#3
Mingxu Da, Jichun Ma, Yongbin Zhang, Jian Yang, Jibin Yao, Boyuan Huang, Hong Ma, Long Ge
PURPOSE: Although several studies have investigated the association between the development of gastric cancer (GC) and the expression level of long non-coding (lnc) RNA HOTAIR, no clear evidence about whether its expression is associated with the overall survival (OS) of GC patients exists. In this study we tried to explore the association between lncRNA HOTAIR expression levels with OS and other clinical features in GC patients. METHODS: Databases including PubMed, EMBASE and the Cochrane Library were used to search eligible studies...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29155225/a-systematic-review-of-the-long-term-effectiveness-of-work-based-lifestyle-interventions-to-tackle-overweight-and-obesity
#4
REVIEW
Greta Tam, May P S Yeung
Obesity is one of the five leading global risks for mortality, accounting for 5% of deaths worldwide. Workplace health promotion programs have the potential to deliver population-level interventions combining physical activity and exercise. However, there is no recent critical review of trials on long-term effectiveness of multicomponent lifestyle interventions in the workplace targeting obesity. Good quality evidence is needed to develop optimal strategies to tackle adult obesity. 1035 studies were retrieved by literature search in MEDLINE, Embase, PSYCH INFO and Cochrane library from 2005 to September 2016...
November 16, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29154815/vitamin-d-and-new-onset-atrial-fibrillation-a-meta-analysis-of-randomized-controlled-trials
#5
REVIEW
Wei-Ling Huang, Jun Yang, Jian Yang, Hui-Bo Wang, Chao-Jun Yang, Ying Yang
OBJECTIVES: To research vitamin D levels in the prevention of new-onset atrial fibrillation(AF), we conducting a systematic review of randomised controlled trials (RCTs). METHODS: The MEDLINE, EMBASE and Cochrane Library were searched for English-language RCTs published before September 2016.We focus on the vitamin D levels in the prevention of new-onset AF. The outcomes assessed were vitamin D levels, left ventricular ejection fraction (LVEF) and Left atrium diameter...
November 14, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29154691/optimal-screening-methods-to-detect-cardiac-disorders-in-athletes-an-evidence-based-review
#6
Zachary K Winkelmann, Ashley K Crossway
Reference/Citation:  Harmon KG, Zigman M, Drezner JA. The effectiveness of screening history, physical exam, and ECG to detect potentially lethal cardiac disorders in athletes: a systematic review/meta-analysis. J Electrocardiol. 2015;48(3):329-338. CLINICAL QUESTION:   Which screening method should be considered best practice to detect potentially lethal cardiac disorders during the preparticipation physical examination (PE) of athletes? DATA SOURCES:   The authors completed a comprehensive literature search of MEDLINE, CINAHL, Cochrane Library, Embase, Physiotherapy Evidence Database (PEDro), and SPORTDiscus from January 1996 to November 2014...
November 20, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/29154263/the-effectiveness-of-proprioceptive-and-neuromuscular-training-compared-to-bracing-in-reducing-the-recurrence-rate-of-ankle-sprains-in-athletes-a-systematic-review-and-meta-analysis
#7
M Burger, D Dreyer, R L Fisher, D Foot, D H O'connor, M Galante, S Zalgaonkir
BACKGROUND: Ankle sprains are common musculoskeletal injuries in which the ligaments of the ankle partially or completely tear due to sudden stretching. OBJECTIVES: To critically appraise, evaluate and establish the best available evidence to determine the effectiveness of proprioceptive and neuromuscular training (PNT) compared to bracing in reducing the recurrence rate of ankle sprains in athletes. METHODOLOGY: The following seven databases were searched in June 2017: PubMed, Cochrane Library, PEDro, ScienceDirect, Scopus, SPORTDiscus, EBSCO Host: CINAHL...
November 10, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29154122/broncho-vaxom-in-pediatric-recurrent-respiratory-tract-infections-a-systematic-review-and-meta-analysis
#8
REVIEW
Ju Yin, Baoping Xu, Xiantao Zeng, Kunling Shen
OBJECTIVES: Assess the efficacy and safety of Broncho-Vaxom in pediatric recurrent respiratory tract infections (RRTIs). METHODS: Published randomized controlled trials (RCTs) of Broncho-Vaxom for pediatric RRTI were searched using PubMed, Embase, Cochrane Library, CBM, CNKI, WanFang Data, and VIP databases up to January 2017. Risk of bias was evaluated in accordance to the guidelines of the Cochrane collaboration and the level of evidence was graded according to the GRADE...
November 16, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/29153510/resumption-of-antiplatelet-therapy-in-patients-with-primary-intracranial-hemorrhage-benefits-and-risks-a-meta-analysis-of-cohort-studies
#9
REVIEW
Xueying Ding, Xi Liu, Changhong Tan, Maojia Yin, Teng Wang, Ying Liu, Lijuan Mo, Xin Wei, Xinjie Tan, Fen Deng, Lifen Chen
BACKGROUND: Clinical disagreement over antiplatelet (AP) resumption in patients with primary intracranial hemorrhage (ICH) has long existed. This meta-analysis aimed to evaluate the benefits of AP resumption on preventing ischemic or thromboembolic events against its risks of promoting ICH recurrence or hematoma expansion. METHODS: All relevant articles published in Pubmed, EMBASE, the Cochrane Library, and Science Direct from January 1950 to March 2017 were sourced, and the combined relative risk (RR) was calculated...
November 10, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29153429/optimal-interval-to-surgery-after-neoadjuvant-chemoradiotherapy-in-rectal-cancer-a%C3%A2-systematic-review-and-meta-analysis
#10
REVIEW
Donglin Du, Zhourong Su, Dan Wang, Wenwen Liu, Zhengqiang Wei
This study aimed to evaluate the influence of a waiting interval of ≥ 8 weeks between the end of preoperative neoadjuvant chemoradiotherapy (nCRT) and surgery on the outcomes of patients with locally advanced rectal cancer. We conducted a comprehensive literature review of retrospective and prospective studies from PubMed, Embase, and Cochrane Library databases to investigate the length of the preoperative nCRT-surgery waiting interval and outcomes in patients with locally advanced rectal cancer. The primary outcome measure was pathologic complete response (pCR) rate...
November 15, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29153114/cost-effectiveness-analyses-of-antihypertensive-medicines-a-systematic-review
#11
REVIEW
Chanhyun Park, Guijing Wang, Jefferey M Durthaler, Jing Fang
CONTEXT: Hypertension affects one third of the U.S. adult population. Although cost-effectiveness analyses of antihypertensive medicines have been published, a comprehensive systematic review across medicine classes is not available. EVIDENCE ACQUISITION: PubMed, Embase, Cochrane Library, and Health Technology Assessment were searched to identify original cost-effectiveness analyses published from 1990 through August 2016. Results were summarized by medicine class: angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), calcium channel blockers (CCBs), thiazide-type diuretics, β-blockers, and others...
December 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29152522/bone-patellar-tendon-bone-versus-hamstring-tendon-autografts-for-primary-anterior-cruciate-ligament-reconstruction-a-systematic-review-of-overlapping-meta-analyses
#12
REVIEW
Hayden B Schuette, Matthew J Kraeutler, Darby A Houck, Eric C McCarty
Background: Previous meta-analyses have compared bone-patellar tendon-bone (BPTB) with hamstring tendon (HT) autografts for primary anterior cruciate ligament reconstruction (ACLR). Purpose: To conduct a systematic review of overlapping meta-analyses comparing BPTB with HT autografts for ACLR to determine which meta-analyses provide the best available evidence. Study Design: Systematic review; Level of evidence, 4. Methods: A systematic review was performed by searching the PubMed and Cochrane Library databases...
November 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29151988/lumbar-spinal-angiolipoma-with-expanding-left-neural-foramen-mimicking-lumbar-schwannoma-case-report-and-review-of-the-literature
#13
Yener Akyuva, Aylin Gonultas, Numan Karaaslan, Zehra Gulciftci Dagci, Semih Saglik, Mehmet Isyar, Mahir Mahirogullari
Aim: To describe a patient with lumbar angiolipoma mimicking schwannoma in the posterolateral side of the spinal canal with expansion of the left lumbar foramen and to discuss the clinical, radiologic, and surgical features of these lesions with literature. Methods: Without language restriction in this paper, the electronic databases; The Cochrane Collaboration the Cochrane, The Cochrane Library (Issue 2 of 12, Feb. 2011), ProQuest, US National Library of Medicine, National Institutes of Health (NLM) and PubMed dating from 1966 September to January Week 2 2017, were searched for comparative experimental studies using the terms: "OR", "AND"...
2017: Open Neurology Journal
https://www.readbyqxmd.com/read/29151893/defining-the-gap-a-systematic-review-of-the-difference-in-rates-of-diabetes-related-foot-complications-in-aboriginal-and-torres-strait-islander-australians-and-non-indigenous-australians
#14
REVIEW
Matthew West, Vivienne Chuter, Shannon Munteanu, Fiona Hawke
Background: The Aboriginal and Torres Strait Islander community has an increased risk of developing chronic illnesses including diabetes. Among people with diabetes, foot complications are common and make a significant contribution to the morbidity and mortality associated with this disease. The aim of this review was to systematically evaluate the literature comparing the rates of diabetes related foot complications in Aboriginal and Torres Strait Islander Australians to non-Indigenous Australians...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29151370/systematic-review-of-infant-and-young-child-complementary-feeding-practices-in-south-asian-families-the-pakistan-perspective
#15
Logan Manikam, Anika Sharmila, Abina Dharmaratnam, Emma C Alexander, Jia Ying Kuah, Ankita Prasad, Sonia Ahmed, Raghu Lingam, Monica Lakhanpaul
OBJECTIVE: Suboptimal nutrition among children remains a problem among South Asian (SA) families. Appropriate complementary feeding (CF) practices can greatly reduce this risk. Thus, we undertook a systematic review of studies assessing CF (timing, dietary diversity, meal frequency and influencing factors) in children aged <2 years in Pakistan. DESIGN: Searches between January 2000 and June 2016 in MEDLINE, EMBASE, Global Health, Web of Science, OVID Maternity & Infant Care, CINAHL, Cochrane Library, BanglaJOL, POPLINE and WHO Global Health Library...
November 20, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29150467/interventions-to-improve-adherence-to-reporting-guidelines-in-health-research-a-scoping-review-protocol
#16
David Blanco, Jamie J Kirkham, Douglas G Altman, David Moher, Isabelle Boutron, Erik Cobo
INTRODUCTION: There is evidence that the use of some reporting guidelines, such as the Consolidated Standards for Reporting Trials, is associated with improved completeness of reporting in health research. However, the current levels of adherence to reporting guidelines are suboptimal. Over the last few years, several actions aiming to improve compliance with reporting guidelines have been taken and proposed. We will conduct a scoping review of interventions to improve adherence to reporting guidelines in health research that have been evaluated or suggested, in order to inform future interventions...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150458/diagnostic-accuracy-of-neonatal-assessment-for-gestational-age-determination-a-systematic-review
#17
REVIEW
Anne Cc Lee, Pratik Panchal, Lian Folger, Hilary Whelan, Rachel Whelan, Bernard Rosner, Hannah Blencowe, Joy E Lawn
CONTEXT: An estimated 15 million neonates are born preterm annually. However, in low- and middle-income countries, the dating of pregnancy is frequently unreliable or unknown. OBJECTIVE: To conduct a systematic literature review and meta-analysis to determine the diagnostic accuracy of neonatal assessments to estimate gestational age (GA). DATA SOURCES: PubMed, Embase, Cochrane, Web of Science, POPLINE, and World Health Organization library databases...
November 17, 2017: Pediatrics
https://www.readbyqxmd.com/read/29150165/effects-of-programmed-exercise-on-depressive-symptoms-in-midlife-and-older-women-a-meta-analysis-of-randomized-controlled-trials
#18
REVIEW
Faustino R Pérez-López, Samuel J Martínez-Domínguez, Héctor Lajusticia, Peter Chedraui
OBJECTIVE: To perform a systematic review and meta-analysis to clarify the effect of programmed exercise on depressive symptoms (DSs) in midlife and older women. METHODS: We carried out a structured search of PubMed-Medline, Web of Science, Scopus, Embase, Cochrane Library and Scielo, from database inception through June 29, 2017, without language restriction. The search included the following terms: "depression", "depressive symptoms", "exercise", "physical activity", "menopause", and "randomized controlled trial" (RCTs) in midlife and older women...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29150156/the-efficacy-of-danshen-injection-as-adjunctive-therapy-in-treating-angina-pectoris-a-systematic-review-and-meta-analysis
#19
REVIEW
Huikai Shao, Mengsi Li, Fuchao Chen, Lianghua Chen, Zhengjin Jiang, Lingguo Zhao
BACKGROUND: During the last 40 years, Danshen injection has been widely used as an adjunctive therapy for angina pectoris in China, but its efficacy is not yet well defined. The objective of this study was to verify the efficacy of Danshen injection as adjunctive therapy in treating angina pectoris. METHODS: The major databases including PubMed, Cochrane Library, Sino-Med, Medline, Embase, Google Scholar, China National Knowledge Infrastructure, Wanfang Databases, Chinese Scientific Journal Database, Chinese Biomedical Literature Database and the Chinese Science Citation Database were systematically searched for the published randomised controlled trials (RCTs) on Danshen injection until April 2016...
November 6, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29149823/olive-oil-related-anti-inflammatory-effects-on-atherosclerosis-potential-clinical-implications
#20
Tanakal Wongwarawipat, Nikolaos Papageorgiou, Dimitrios Bertsias, Gerasimos Siasos, Dimitris Tousoulis
BACKGROUND AND OBJECTIVE: Atherosclerosis is characterized by a chronic low-grade inflammatory process which can result in atherothrombosis and a number of cardiovascular diseases (CVD). It is believed to be caused by multiple processes that involve inflammation and immunity. Mediterranean Diet (MedD) has been discovered to possess anti-inflammatory properties and associated with a reduction in the CVD risk and mortality. Its main component, extra-virgin olive oil (EVOO), is believed to be largely responsible for these effects and therefore, has been investigated in various studies...
November 15, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
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