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https://www.readbyqxmd.com/read/28343029/meta-analysis-of-transhiatal-esophagectomy-in-carcinoma-of-esophagogastric-junction-does-it-have-an-advantage
#1
REVIEW
Rong Yan, Chengxue Dang
PURPOSE: Compare the clinical outcome of Transhiatal Esophagectomy (THE) approach and open Thoracic Esophagectomy (TTE) approach in the carcinoma of esophagogastric junction (CEGJ). METHODS: Relevant literature published until 2016 from PubMed, Cochrane Library, Ovid (Medline) and EMBASE were retrieved. Meta-analysis was achieved by using the Stata12 software. RESULTS: A total of 18 studies and 2202 cases of patients were involved in this meta-analysis...
March 22, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28342907/active-placebo-control-groups-of-pharmacological-interventions-were-rarely-used-but-merited-serious-consideration-a-methodological-overview
#2
Jakob Solgaard Jensen, Andreas Ørsted Bielefeldt, Asbjørn Hróbjartsson
OBJECTIVES: Active placebos are control interventions that mimic the side-effects of the experimental interventions in randomised trials and are sometimes used to reduce the risk of unblinding. We wanted to assess how often randomised clinical drug trials implement active placebo control groups; to provide a catalogue, and a characterisation, of such trials; and to analyse methodological arguments for and against use of active placebo. STUDY DESIGN: An overview consisting of three thematically linked sub-studies...
March 22, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28340066/diagnostic-test-accuracy-of-ultrasound-for-synovitis-in-rheumatoid-arthritis-systematic-review-and-meta-analysis
#3
Kaoru Takase-Minegishi, Nobuyuki Horita, Kouji Kobayashi, Ryusuke Yoshimi, Yohei Kirino, Shigeru Ohno, Takeshi Kaneko, Hideaki Nakajima, Richard J Wakefield, Paul Emery
Objective.: To evaluate diagnostic test accuracy of US compared with MRI for the detection of synovitis in RA patients. Methods.: A systematic literature search was performed in the PubMed, EMBASE, Cochrane Library and Web of Science Core Collection databases. Studies evaluating the diagnostic test accuracy of US for synovitis detected by MRI as the reference standard for wrist, MCP, PIP and knee joints were included. To assess the overall accuracy, we calculated the diagnostic odds ratio using a DerSimonian-Laird random effects model and the area under the curve (AUC) for the hierarchical summary receiver operating characteristics using Holling's proportional hazards models...
March 3, 2017: Rheumatology
https://www.readbyqxmd.com/read/28340005/inappropriate-shocks-in-single-chamber-and-subcutaneous-implantable-cardioverter-defibrillators-a-systematic-review-and-meta-analysis
#4
Angelo Auricchio, J Harrison Hudnall, Edward J Schloss, Laurence D Sterns, Takashi Kurita, Albert Meijer, Dedra H Fagan, Tyson Rogers
Aims: Single-chamber (VR-ICD) and subcutaneous (S-ICD) implantable cardioverter-defibrillators are effective to protect patients against sudden death but expose them to higher risk of inappropriate shock (IS). We sought to quantify the annual rate and influencing factors of ISs in VR- and S-ICDs from the literature. Methods and results: PubMed, Embase, and Cochrane Library were searched for full text articles with IS rates. Poisson distribution estimated proportion of patients with ISs; rates were annualized based on follow-up duration...
March 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28339835/the-association-between-proton-pump-inhibitor-use-and-the-risk-of-adverse-kidney-outcomes-a-systematic-review-and-meta-analysis
#5
Surapon Nochaiwong, Chidchanok Ruengorn, Ratanaporn Awiphan, Kiatkriangkrai Koyratkoson, Chayutthaphong Chaisai, Kajohnsak Noppakun, Wilaiwan Chongruksut, Kednapa Thavorn
Background: Existing epidemiological studies illustrate that proton pump inhibitors (PPIs) may be related to adverse kidney outcomes. To date, no comprehensive meta-analysis has been conducted to evaluate and quantify this association. Methods: We performed a systematic review and meta-analysis of studies to assess the association between PPI use and the risk of adverse kidney outcomes. We searched MEDLINE, Embase, SCOPUS, Web of Science, CINAHL, Cochrane Library and grey literature with no language restrictions (through 31 October 2016)...
February 23, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28339493/timely-meta-analysis-on-the-efficacy-of-adoptive-immunotherapy-for-hepatocellular-carcinoma-patients-after-curative-therapy
#6
Han-Yue Mo, Ying-Yang Liao, Xue-Mei You, Alessandro Cucchetti, Bao-Hong Yuan, Ru-Hong Li, Jian-Hong Zhong, Le-Qun Li
AIMS: The role of adoptive immunotherapy (AIT) for patients with hepatocellular carcinoma (HCC) who have received curative therapy is still not well illustrated. This timely meta-analysis aims to update the current evidence on efficacy and safety of AIT for patients with HCC who have received curative therapy. METHODS: We searched PubMed, EMBASE, Scopus and the Cochrane Library Through January 2017 for relevant studies. Mortality and tumor recurrence were compared between patients with or without adjuvant AIT...
2017: PloS One
https://www.readbyqxmd.com/read/28338811/interventions-for-the-prevention-and-treatment-of-disability-due-to-acquired-joint-contractures-in-older-people-a-systematic-review
#7
Susanne Saal, Katrin Beutner, Julia Bogunski, Kathrin Obermüller, Martin Müller, Eva Grill, Gabriele Meyer
Background: acquired joint contractures have significant effects on quality of life and functioning. Objective: to determine the effects of interventions to prevent and treat disabilities in older people with acquired joint contractures. Methods: systematic search (last 8/2016) via Cochrane Library, PubMed, EMBASE, PEDro, CINAHL, trial registries, reference lists of retrieved articles and scientific congress pamphlets. Controlled and randomised controlled trials in English or German comparing an intervention with another intervention or standard care were included...
February 25, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28338807/is-orthostatic-hypotension-related-to-falling-a-meta-analysis-of-individual-patient-data-of-prospective-observational-studies
#8
Laura Caroline Hartog, Dennis Schrijnders, G W D Landman, Klaas Groenier, Nanne Kleefstra, Henk J G Bilo, Kornelis Johannes Jongers van Hateren
Background: orthostatic hypotension (OH) is one out of many risk factors believed to contribute to an increased fall risk in elderly subjects but it is unclear whether an independent association between OH and falling exists. Objectives: to perform an individual patient data (IPD) meta-analysis of prospective observational studies investigating the relationship between OH and falling. Design: MEDLINE, EMBASE, the Cochrane Library and the abstracts of annual meetings of selected hypertension societies were searched...
February 25, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28338169/-meta-analysis-of-extralevator-abdominoperineal-excision-for-rectal-cancer
#9
Yilin Chen, Pan Chi
OBJECTIVE: To evaluate the efficacy of extralevator abdominoperineal excision (ELAPE) of rectal cancer. METHODS: PubMed, Cochrane Library and Embase database were searched for clinical studies comparing the ELAPE and abdominoperineal excision (APE) for rectal cancer between 2007 and 2016. Two reviewers independently screened the articles and extracted the data. The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of the observational studies and the score more than 5 points was the inclusion criteria...
March 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28338168/-safety-and-efficacy-of-hand-assisted-laparoscopic-versus-open-distal-gastrectomy-for-gastric-cancer-a-systematic-review-and-meta-analysis
#10
Guibing Chen, Xiaoqian Xu, Jiaqing Gong, Guohu Zhang, Yongkuan Cao, Lin Zhang
OBJECTIVE: To systematically assess the safety and efficacy of hand-assisted laparoscopic distal gastrectomy (HALG) versus open distal gastrectomy (ODG) for gastric cancer. METHODS: Chinese or English literature regarding comparison of HALG and ODG were collected by searching in databases (such as PubMed, Cochrane Library, CNKI, Wanfang database) between January 1996 and September 2016. The data of operative time, incision length, blood loss, number of harvested lymph nodes, time to flatus, hospital stay, postoperative complication morbidity and long-term outcomes were compared between the two procedures...
March 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28338036/to-cord-or-not-to-cord-that-is-still-a-question
#11
Analia Veitz-Keenan, James R Keenan
Data sourcesA broad computerised search with similar key terms was performed in different databases that included: Ovid Medline, Thomson's ISI Web of Science, PubMed, Science Direct, EMBASE and the Cochrane Library. Grey literature, dissertations, abstracts and theses were searched too. Reference lists of the selected articles were hand-searched.Study selectionThe inclusion criteria included in vivo randomised clinical trials and quasi-randomised clinical trials using gingival retraction techniques with and without cord...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28338032/reliability-of-cbct-diagnosing-root-fractures-remains-uncertain
#12
Niloufar Amintavakoli, Silvia Spivakovsky
Data sourcesPubMed, Web of Science, Science Direct, Cochrane library, Embase, SCOPUS, CNKI and Wanfang databases were searched until April 2014 followed by hand searching of relevant references.Study selectionUsing no language restrictions two authors independently assessed for inclusion of in vivo and in vitro studies involving at least ten teeth on the use of CBCT for diagnosing complete root fractures on non-endodontically treated teeth.Data extraction and synthesisTwo authors independently assessed for inclusion and performed quality assessment using QUADAS-2 (quality assessment of studies of diagnostic accuracy-2)...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28338025/preventing-perioperative-bleeding-in-patients-with-inherited-bleeding-disorders
#13
Colin Watterson, Nicholas Beacher
Data sourcesCochrane Cystic Fibrosis and Genetic Disorders Group's Coagulopathies Trials Register, a regularly updated database informed by trials identified within electronic databases including MEDLINE. Further defined searches were undertaken in PubMed, Embase, The Cochrane Library, ClinicalTrials.gov and WHO International Clinical Trials Registry Platform. Additional hand searching of relevant journals and books of conference proceedings was undertaken.Study selectionRandomised and quasi-randomised controlled trials in people of all ages with haemophilia or VWD undergoing oral or dental procedures using antifibrinolytic agents (tranexamic acid (TXA) or epsilon aminocaproic acid (EACA)) to prevent perioperative bleeding compared to no intervention with or without placebo...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28338024/evidence-for-use-of-intraoral-scanners-under-clinical-conditions-for-obtaining-full-arch-digital-impressions-is-insufficient
#14
Hadil Khraishi, Brett Duane
Data sourcesPubMed, Scopus, Cochrane Library, Web of Science, Embase. Relevant papers were also searched from the reference lists of selected studies. A web search of current manufacturers of intraoral scanners.Study selectionStudies with full-arch digital impressions recorded intraorally that tested any of the following outcomes; validity, repeatability, reproducibility, time efficiency. Patient acceptance of digital impressions were considered for the review.Data extraction and synthesisInitially, only titles of the papers identified from the databases were screened, then further screening of the abstracts of the selected titles was carried out...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28337998/circulating-tumor-cell-status-monitors-the-treatment-responses-in-breast-cancer-patients-a-meta-analysis
#15
Wen-Ting Yan, Xiang Cui, Qing Chen, Ya-Fei Li, You-Hong Cui, Yan Wang, Jun Jiang
Whether circulating tumor cells (CTCs) can be used as an indicator of treatment response in breast cancer (BC) needs to be clarified. We addressed this issue by a meta-analysis. PubMed, EMBase and Cochrane library databases were searched in June 2016. Effect measures were estimated as pooled risk ratio (RR), odds ratio (OR) or mean difference by fixed- or random-effect models, according to heterogeneity of included studies. In total, 50 studies with 6712 patients were recruited. Overall analysis showed that there was a significant reduction of CTC-positive rate (RR = 0...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28337750/efficacy-and-safety-of-the-drugs-used-to-reverse-direct-oral-anticoagulants-a-systematic-review-and-meta-analysis
#16
REVIEW
Luis Teodoro da Luz, Mylene Marchand, Bartolomeu Nascimento, Homer Tien, Avery Nathens, Prakesh Shah
BACKGROUND: Direct oral anticoagulants (DOACs) are effective and safe for prophylaxis and treatment of thromboembolic phenomena. However, managing DOACs during bleeding emergencies is challenging. A systematic review and meta-analysis was conducted on studies addressing efficacy and safety of the drugs used for reversal of DOACs. STUDY DESIGN AND METHODS: Medline, Embase, Cochrane Library, and ClinicalTrials.gov were searched up to September 2016. Studies that examined clinical and laboratory effects of drugs used to reverse DOACs were included...
March 24, 2017: Transfusion
https://www.readbyqxmd.com/read/28337546/robotic-thyroidectomy-versus-conventional-open-thyroidectomy-for-thyroid-cancer-a-systematic-review-and-meta-analysis
#17
Jing-Hua Pan, Hong Zhou, Xiao-Xu Zhao, Hui Ding, Li Wei, Li Qin, Yun-Long Pan
BACKGROUND: Despite the new technical alternative offered by the robotic surgery for minimally invasive thyroid surgery, the role of the robotic thyroidectomy (RT) in thyroid cancer has been highly disputed. This paper gives a systematic review and meta-analysis aiming to compare RT and open thyroidectomy (OT) based on the surgical outcomes and oncologic results. METHODS: Relevant literature was searched from various databases up to July 2016, including PubMed, MEDLINE, EMBASE, Cochrane Library, Web of science and Clinical Trials...
March 23, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28337228/evaluation-of-efficacy-and-safety-of-dan-e-fukang-soft-extract-in-the-treatment-of-endometriosis-a-meta-analysis-of-39-randomized-controlled-trials-enrolling-5442-patients
#18
REVIEW
Yantao Li, Te Li, Shilin Song
Objective. To systematically evaluate the efficacy and safety of Dan'e-fukang soft extract in endometriosis treatment. Method. PubMed, CNKI, Wanfang Database, VIP, SinoMed, and Cochrane Library were searched. Randomized controlled trials (RCTs) comparing the efficacy of Dan'e-fukang soft extract and conventional western medicines for endometriosis treatment were included. The data were extracted independently by two people and analyzed using RevMan 5.2.0 software. The relative risk (RR) and mean difference (MD) with 95% confidence intervals were considered as effective outcome indicators...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28336735/risk-of-tuberculosis-in-patients-treated-with-tnf-%C3%AE-antagonists-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#19
Zheng Zhang, Wei Fan, Gui Yang, Zhigao Xu, June Wang, Qingyuan Cheng, Mingxia Yu
OBJECTIVES: An increased risk of tuberculosis (TB) has been reported in patients treated with TNF-α antagonists, an issue that has been highlighted in a WHO black box warning. This review aimed to assess the risk of TB in patients undergoing TNF-α antagonists treatment. METHODS: A systematic literature search for randomised controlled trials (RCTs) was performed in MEDLINE, Embase and Cochrane library and studies selected for inclusion according to predefined criteria...
March 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28336402/post-operative-efficacy-predictability-safety-and-visual-quality-of-laser-corneal-refractive-surgery-a-network-meta-analysis
#20
Daizong Wen, Colm McAlinden, Ian Flitcroft, Ruixue Tu, Qinmei Wang, Jorge Alió, John Marshall, Yingying Huang, Benhao Song, Liang Hu, Yune Zhao, Senmiao Zhu, Rongrong Gao, Fangjun Bao, Ayong Yu, Ye Yu, Hengli Lian, Jinhai Huang
PURPOSE: To compare the post-operative efficacy, predictability, safety and visual quality of all major forms of laser corneal refractive surgeries for correcting myopia. DESIGN: Systematic review and network meta-analysis. METHODS: MEDLINE, EMBASE, Cochrane Library and the US trial registry was conducted up to November 2015. Randomized controlled trials (RCT) reporting in accordance with the eligibility criteria were included in this review...
March 20, 2017: American Journal of Ophthalmology
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