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https://www.readbyqxmd.com/read/29774777/current-research-status-of-palliative-care-in-mainland-china
#1
Tao Wang, Alex Molassiotis, Betty Pui Man Chung, Jing-Yu Tan
OBJECTIVES: This study aimed to obtain an overview of the current research status of palliative care in Mainland China and identify research directions for future studies by characterizing palliative care studies conducted among patients with any life-limiting illness in Mainland China and published in a peer-reviewed journal before November 2016. METHODS: A review guide with 7 categories was initially developed based on existing international palliative care definitions and guidelines through content analysis...
January 1, 2018: Journal of Palliative Care
https://www.readbyqxmd.com/read/29774377/effect-of-childhood-socioeconomic-conditions-on-cancer-onset-in-later-life-an-ambidirectional-cohort-study
#2
Bernadette W A van der Linden, Delphine S Courvoisier, Boris Cheval, Stefan Sieber, Piet Bracke, Idris Guessous, Claudine Burton-Jeangros, Matthias Kliegel, Stéphane Cullati
OBJECTIVES: Living in low socioeconomic conditions during childhood is associated with poor health outcomes in later life. Whether this link also applies to cancer is unclear. We examined whether childhood socioeconomic conditions (CSCs) are associated with cancer risk in later life and whether this effect remained after adjusting for adulthood socioeconomic conditions (ASCs). METHODS: Data for 26,431 individuals ≥ 50 years old included in SHARE were analysed...
May 17, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29773356/a-web-based-overview-systematic-review-and-meta-analysis-of-pancreatic-anastomosis-techniques-following-pancreatoduodenectomy
#3
REVIEW
Lois A Daamen, F Jasmijn Smits, Marc G Besselink, Olivier R Busch, Inne H Borel Rinkes, Hjalmar C van Santvoort, I Quintus Molenaar
BACKGROUND: Many pancreatic anastomoses have been proposed to reduce the incidence of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy, but a complete overview is lacking. This systematic review and meta-analysis aims to provide an online overview of all pancreatic anastomosis techniques and to evaluate the incidence of clinically relevant POPF in randomized controlled trials (RCTs). METHODS: A literature search was performed to December 2017...
May 14, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29772082/child-symptoms-parent-behaviors-and-family-strain-in-long-term-survivors-of-childhood-acute-lymphoblastic-leukemia
#4
I-Chan Huang, Tara M Brinkman, Larry Mullins, Ching-Hon Pui, Leslie L Robison, Melissa M Hudson, Kevin R Krull
BACKGROUND: How family environment and parental factors affect health status and symptoms in childhood cancer survivors is understudied. We examined the influence of family cohesion, parent distress, and overprotection on child symptom burden and health-related quality of life (HRQOL) and family strain in survivors of childhood acute lymphoblastic leukemia (ALL). METHODS: Parents of 213 children treated with chemotherapy-only completed a survey when survivors were at least five-years post-diagnosis...
May 17, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29771686/spleen-mediates-a-distinct-hematopoietic-progenitor-response-supporting-tumor-promoting-myelopoiesis
#5
Chong Wu, Huiheng Ning, Mingyu Liu, Jie Lin, Shufeng Luo, Wenjie Zhu, Jing Xu, Wen-Chao Wu, Jing Liang, Chun-Kui Shao, Jiaqi Ren, Bin Wei, Jun Cui, Min-Shan Chen, Limin Zheng
Cancer progression is associated with alterations of intra- and extramedullary hematopoiesis to support a systemic tumor-promoting myeloid response. However, the functional specialty, mechanism, and clinical relevance of extramedullary hematopoiesis (EMH) remain unclear. Here we showed that the heightened splenic myelopoiesis in tumor-bearing hosts was not only characterized by the accumulation of myeloid precursors, but also associated with profound functional alterations of splenic early hematopoietic stem/progenitor cells (HSPCs)...
May 17, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29770621/are-patients-and-physicians-willing-to-accept-less-radical-procedures-for-cervical-cancer
#6
Kemal Gungorduk, Roman Kocian, Derman Basaran, Taner Turan, Aykut Ozdemir, David Cibula
OBJECTIVE: To evaluate the opinions of women who underwent surgery for cervical cancer (CC) and physicians who treat CC about the acceptability of increased oncological risk after less-radical surgery. METHODS: One hundred eighty-two women who underwent surgery for CC and 101 physicians participated in a structured survey in 3 tertiary cancer centers in Czech Republic and Turkey. Patients and physicians were asked whether they would accept any additional oncological risks, which would be attributable to the omission of parametrectomy (radical hysterectomy/trachelectomy vs...
March 12, 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29769386/global-acceptance-of-biosimilars-importance-of-regulatory-consistency-education-and-trust
#7
REVIEW
Eduardo Cazap, Ira Jacobs, Ali McBride, Robert Popovian, Karol Sikora
Globally, biosimilars are expected to have a key role in improving patient access to biological therapies and addressing concerns regarding the escalating cost of health care. Indeed, in Europe, increased use of biologics and reduced drug prices have been observed after the introduction of biosimilars. Recently, several monoclonal antibody biosimilars of anticancer therapies have been approved, and numerous others are in various stages of clinical development. Biosimilars are authorized via a regulatory pathway separate from that used for generic drugs; they are also regulated separately from novel biologics...
May 16, 2018: Oncologist
https://www.readbyqxmd.com/read/29769124/knowledge-towards-cervical-cancer-prevention-and-screening-practices-among-women-who-attended-reproductive-and-child-health-clinic-at-magu-district-hospital-lake-zone-tanzania-a-cross-sectional-study
#8
Mabula M Mabelele, John Materu, Faraja D Ng'ida, Michael J Mahande
BACKGROUND: Cervical cancer is a global leading cause of morbidity and mortality, attributable to the death of approximately 266,000 women every year. Majority (87%) of cervical cancer deaths occur in developing countries including Tanzania. Though knowledge of cervical cancer is an important determinant of women's participation in prevention and screening for cervical cancer, little is known about this topic in Tanzania. This study aimed to determine the knowledge of cervical cancer prevention services and screening practices among women who attended Reproductive Child Health clinic at a district hospital in Lake Zone, Tanzania...
May 16, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29768942/updated-meta-review-of-evidence-on-support-for-carers
#9
Jane Dalton, Sian Thomas, Melissa Harden, Alison Eastwood, Gillian Parker
Objective To update a 2010 meta-review of systematic reviews of effective interventions to support carers of ill, disabled, or older adults. In this article, we report the most promising interventions based on the best available evidence. Methods Rapid meta-review of systematic reviews published from January 2009 to 2016. Results Sixty-one systematic reviews were included (27 high quality, 25 medium quality, and nine low quality). The quality of reviews has improved since the original review, but primary studies remain limited in quality and quantity...
January 1, 2018: Journal of Health Services Research & Policy
https://www.readbyqxmd.com/read/29764891/developing-a-complex-intervention-to-support-timely-engagement-with-palliative-care-for-patients-with-advanced-cancer-in-primary-and-secondary-care-in-the-uk-a-study-protocol
#10
Julia Hackett, Hilary Bekker, Michael I Bennett, Paul Carder, Jean Gallagher, Claire Henry, Suzanne Kite, Sally Taylor, Galina Velikova, Lucy Ziegler
INTRODUCTION: For patients with advanced cancer, timely access to palliative care can improve quality of life and enable patients to participate in decisions about their end-of-life care. However, in a UK population of 2500 patients who died from cancer, one-third did not receive specialist palliative care, and of those who did, the duration of involvement was too short to maximise the benefits. Initiating a conversation about palliative care is challenging for some health professionals and patients often have unmet information needs and misconceptions about palliative care...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29764801/assessing-unmet-information-needs-of-breast-cancer-survivors-exploratory-study-of-online-health-forums-using-text-classification-and-retrieval
#11
Susan McRoy, Majid Rastegar-Mojarad, Yanshan Wang, Kathryn J Ruddy, Tufia C Haddad, Hongfang Liu
BACKGROUND: Patient education materials given to breast cancer survivors may not be a good fit for their information needs. Needs may change over time, be forgotten, or be misreported, for a variety of reasons. An automated content analysis of survivors' postings to online health forums can identify expressed information needs over a span of time and be repeated regularly at low cost. Identifying these unmet needs can guide improvements to existing education materials and the creation of new resources...
May 15, 2018: JMIR Cancer
https://www.readbyqxmd.com/read/29764524/a-qualitative-examination-of-the-factors-related-to-the-development-and-maintenance-of-insomnia-in-cancer-survivors
#12
Sheila N Garland, Frances K Barg, Brigid Cakouros, Philip Gehrman, Katherine N DuHamel, Jun J Mao
OBJECTIVE: Insomnia is underrecognized and inadequately managed, with close to 60% of cancer survivors experiencing insomnia at some point in the treatment trajectory. The objective of this study was to further understand predisposing, precipitating, and perpetuating factors in the development and maintenance of insomnia in cancer survivors. METHOD: A heterogeneous sample of 63 patients who had completed active treatment was recruited. Participants were required to have a score >7 on the Insomnia Severity Index and meet the diagnostic criteria for insomnia disorder...
May 16, 2018: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29764414/patient-awareness-knowledge-towards-oral-cancer-a-cross-sectional-survey
#13
Neel Shimpi, Monica Jethwani, Aditi Bharatkumar, Po-Huang Chyou, Ingrid Glurich, Amit Acharya
BACKGROUND: Oral cancer (OC) is associated with multiple risk factors and high mortality rates and substantially contributes to the global cancer burden despite being highly preventable. This cross-sectional study sought to assess current knowledge, awareness, and behaviors of patients in rural communities surrounding OC risk. METHODS: An anonymous 21-question survey was distributed to patients in waiting rooms of a large integrated medical-dental health system serving north-central Wisconsin...
May 15, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29763754/determinants-of-cancer-treatment-and-mortality-in-older-cancer-patients-using-a-multi-state-model-results-from-a-population-based-study-the-incapac-study
#14
Angéline Galvin, Catherine Helmer, Gaëlle Coureau, Brice Amadeo, Pierre Joly, Camille Sabathé, Alain Monnereau, Isabelle Baldi, Muriel Rainfray, Pierre Soubeyran, Fleur Delva, Simone Mathoulin-Pélissier
INTRODUCTION: Several studies have reported disparities in the care management and survival of older cancer patients. The aim of our study was to identify determinants of treatment administration in this population of cancer patients aged over 65 years taking into account competing risks of death. METHODS: The INCAPAC study is a population-based study. Four cancer registries and three prospective cohort studies on older subjects (age ≥65 years) from Gironde, a French department, were merged to identify older cancer patients...
May 12, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29761752/addressing-cancer-patient-and-caregiver-role-transitions-during-home-hospice-nursing-care
#15
Janella Hudson, Maija Reblin, Margaret F Clayton, Lee Ellington
OBJECTIVE: Many family caregivers and hospice patients experience role changes resulting from advancing illness and the need for increased caregiver responsibility. Successful navigation of conflicts that arise because of these role transitions has been linked to higher quality of patient care and improved caregiver bereavement adjustment. Nursing communication with patients and their caregivers plays an important role in facilitating these transitions. Our objective is to describe patient-caregiver-nurse communication during transitions at end of life...
May 15, 2018: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29760830/patient-and-provider-perspectives-on-adherence-to-and-care-coordination-of-lynch-syndrome-surveillance-recommendations-findings-from-qualitative-interviews
#16
Jennifer L Schneider, Katrina A B Goddard, Kristin R Muessig, James V Davis, Alan F Rope, Jessica E Hunter, Susan K Peterson, Louise S Acheson, Sapna Syngal, Georgia L Wiesner, Jacob A Reiss
Background: Patients with a genetic variant associated with Lynch syndrome (LS) are recommended to undergo frequent and repeated cancer surveillance activities to minimize cancer-related morbidity and mortality. Little is known about how patients and primary care providers (PCPs) track and manage these recommendations. We conducted a small exploratory study of patient and PCP experiences with recommended LS surveillance activities and communication with family members in an integrated health care system...
2018: Hereditary Cancer in Clinical Practice
https://www.readbyqxmd.com/read/29759898/risk-factors-for-human-papillomavirus-detection-in-urine-samples-of-heterosexual-men-visiting-urological-clinics-in-japan
#17
Kazufumi Nakashima, Kazuyoshi Shigehara, Tadaichi Kitamura, Hiroshi Yaegashi, Masayoshi Shimamura, Shohei Kawaguchi, Kouji Izumi, Yoshifumi Kadono, Atsushi Mizokami
OBJECTIVE: The present study aimed to investigate human papillomavirus (HPV) prevalence and identify risk factors for HPV detection in urine samples among heterosexual men attending urological clinics. MATERIALS AND METHODS: Spot urine samples including initial stream were collected from 845 participants, and the cell pellets were preserved into liquid-based cytological solution. After DNA extraction from each sample, HPV-DNA amplification and genotyping were performed using Luminex multiplex polymerase chain reaction...
May 11, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29759259/1-300-days-and-counting-a-risk-model-approach-to-preventing-retained-foreign-objects-rfos
#18
Erika G Duggan, Jimmy Fernandez, Mary May Saulan, Dave L Mayers, Mira Nikolaj, Tamara M Strah, Lystra M Swift, Larissa Temple
BACKGROUND: A retained foreign object (RFO) is a devastating surgical complication that typically results in additional surgeries, increased length of stay, and risk of infections and is potentially fatal. Memorial Sloan Kettering Cancer Center (MSKCC) convened a multidisciplinary task force to undertake an improvement initiative to reduce the frequency of RFO incidents. METHODS: A needs assessment was undertaken using focus group interviews, review of past RFOs, and operating room (OR) observations, and a comprehensive intervention plan was initiated...
May 2018: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29759013/adapting-to-a-shifting-health-care-landscape-illinois-breast-and-cervical-cancer-program-lead-agencies-perspectives
#19
Yamile Molina, Cindy San Miguel, Stephanie Sanz, Liliana San Miguel, Kristin Rankin, Arden Handler
Understanding how safety net programs adapt to systemic health care changes is pivotal for creating feasible recommendations for policy implementation. This study characterizes perspectives of Lead Agency (LA) coordinators of the Illinois Breast and Cervical Cancer Program (IBCCP) in response to sociopolitical changes at state and national levels. Our cross-sectional study included 29 semistructured telephone interviews between December 2015 and January 2016. Respondents indicated some changes in the priority population served, changes in referrals and clinical services, and, a continued commitment to IBCCP...
May 1, 2018: Health Promotion Practice
https://www.readbyqxmd.com/read/29757877/report-from-the-20th-meeting-of-the-european-society-of-gynaecological-oncology-esgo-2017
#20
Kamil Zalewski, Elisa Piovano, Zoia Razumova, Ilker Selcuk, Tanja Nikolova
This is a report from the 20th Meeting of the European Society of Gynaecological Oncology (ESGO) held in Vienna, Austria on November 4 to 7, 2017. The conference offered state-of-the-art educational sessions and oral and poster abstract presentations. The general sessions throughout the meeting focused not only on prevention, screening, diagnosis, treatment, and translational research but also emerging trends, and current innovations in gynecological cancers were discussed. The ESGO-European Society for Radiotherapy and Oncology-European Society of Pathology guidelines on management of cervical cancers were reported for the first time in public...
May 4, 2018: International Journal of Gynecological Cancer
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