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Chronic pain and suffering

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https://www.readbyqxmd.com/read/29925460/the-symptomatology-of-psychological-trauma-in-the-aftermath-of-war-1945-1980-uk-army-veterans-civilians-and-emergency-responders
#1
Alberta Engelbrecht, Howard Burdett, Maria João Silva, Kamaldeep Bhui, Edgar Jones
BACKGROUND: UK veterans suffering from a psychological or psychiatric illness as a consequence of service in the Second World War were entitled to a war pension. Their case files, which include regular medical assessments, are a valuable resource to investigate the nature, distribution and duration of symptoms. METHODS: A standardised form was used to collect data from pension records of a random sample of 500 UK army veterans from the first presentation in the 1940s until 1980...
June 21, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29920067/anti-inflammation-and-joint-lubrication-dual-effects-of-a-novel-hyaluronic-acid-curcumin-nanomicelle-improve-the-efficacy-of-rheumatoid-arthritis-therapy
#2
Zengjie Fan, Jie Li, Jianli Liu, Hongjing Jiao, Bin Liu
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, which can cause endless suffering to the patients and severely impact their normal lives. To treat RA, the drugs in use have many serious side effects, high cost or only focus on their anti-inflammatory mechanisms without taking joint lubrication into consideration. Therefore, in this study, we aim to construct a novel anti-RA drug composed of hyaluronic acid/curcumin (HA/Cur) nanomicelle to resolve these problems. Characterizations show that Cur is bound to HA by ester linkages, and self-assembles to form a spherical nanomicelle with a diameter of around 164 nm under the main driving of the hydrophilic and hydrophobic forces...
June 19, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29916767/development-of-an-ear-cap-in-chronic-suppurative-otitis-media-using-additive-manufacturing-and-triz
#3
Mahesh B Mawale, Abhaykumar Kuthe, Anupama M Mawale, Sandeep W Dahake
The prevalence rate of chronic suppurative otitis media is high and its treatment continues to be a challenge for the otorhinolaryngologists. Due to middle ear infection, there may be pain, hearing loss and spontaneous rupture of the eardrum which results in perforation. Infections can cause a hole in the eardrum as a side effect of otitis media. The patients suffering from ear perforation or having a hole in eardrum require preventing entry of water in the ear. This article describes the development of ear cap using additive manufacturing and TRIZ (a collaborative tool) to prevent the entry of water in the ear during chronic otitis media...
June 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29915913/onabotulinumtoxina-in-the-treatment-of-refractory-chronic-cluster-headache
#4
Christian Lampl, Mirjam Rudolph, Elisabeth Bräutigam
BACKGROUND: Cluster headache (CH) is a clinically well-defined primary headache disorder, approximately 20% of cluster headache sufferers experience recurrent attacks without periods of significant remission. For the treatment of chronic cluster headache (CCH) only limited therapeutic options are available. METHODS: A potential refractory CCH patient group was identified according to the clinical definition of rCCH based on the consensus statement of the European Headache Federation (EHF)...
June 19, 2018: Journal of Headache and Pain
https://www.readbyqxmd.com/read/29913998/early-maladaptive-schemas-in-finnish-adult-chronic-male-and-female-pain-patients
#5
Tom H J Saariaho, Anita S I Saariaho, Irma A Karila, Matti I Joukamaa
Background and aims of the study The connection between chronic pain and traumatic experiences in childhood has been established in several studies. The association of emotional maltreatment with chronic pain has been studied, but to a lesser degree. Schema therapy [24] is an extension of cognitive therapy and presents the early maladaptive schema (EMS) concept. EMSs reflect early, mainly emotional maltreatment. The aim of the present study was to examine the existence of EMSs, the association between EMSs and pain variables and EMS driven patterns...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913933/a-personal-experience-learning-from-two-pain-pioneers-j-j-bonica-and-w-fordyce-lessons-surviving-four-decades-of-pain-practice
#6
Stephen Butler
This article was requested by the Editor, Professor Harald Brevik after listening to a lecture I gave in a similar vein. Harald wanted the information in print and I have done this in a partly autobiographical form to explain how I came to work and learn from both the late John J. Bonica and the late Wilbert Fordyce. Both of these men have been important in different ways to our present pain world. John J. Bonica made many contributions not only in pain but in regional anesthesia and obstetrical anesthesia but not on the same level...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913923/national-guidelines-for-evaluating-pain-patients-legal-right-to-prioritised-health-care-at-multidisciplinary-pain-clinics-in-norway-implemented-2009
#7
Karen Walseth Hara, Petter Borchgrevink
Background All nations are posed with the challenge of deciding how to allocate limited health care resources. A Patients' Rights Law from 1999 gives patients in Norway with a serious health condition, for which there is efficacious and cost-effective treatment, a legal right to receive health care from the National Health Care system. Methods Recently national guidelines have been produced for implementing these legal rights within 32 fields of specialist health care. One of these fields deals with serious chronic pain conditions...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913921/applying-dialectical-behavior-therapy-to-chronic-pain-a-case-study
#8
Steven J Linton
Background and aims Chronic pain patients often present with a host of psychological and somatic problems and are unable to work despite receiving traditional pain management. For example, it is common that patients with persistent pain also suffer from a variety of anxiety and depressive symptoms. Indeed, the regulation of emotions may be one important factor that is associated with the development of persistent pain. Dialectical behavior therapy, a form of cognitive-behavioral therapy, focuses on emotion regulation and has successfully addressed other complex problems...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913873/postherpetic-neuralgia-new-hopes-in-prevention-with-adult-vaccination-and-in-treatment-with-a-concentrated-capsaicin-patch
#9
Ewa Gawecka, Oddbjørn Viken
Background and purpose Postherpetic neuralgia (PHN) is a complication of acute herpes zoster (HZ). The evidence base for management of PHN has increased by recent publications. Therefore, we reviewed incidence of HZ, prevalence, risk factors, and mechanism of PHN pain, prevention and treatment of PHN with special interest in studies on adult vaccination and topical application of lidocaine and concentrated capsaicin patch. Methods We searched databases with an English language restriction: MEDLINE 1944-2011, EMBASE 1988-2011, PubMed, and the Cochrane Controlled Trial Register and Cochrane Library (2011)...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913831/pulsed-radiofrequency-in-peripheral-posttraumatic-neuropathic-pain-a-double-blind-sham-controlled-randomized-clinical-trial
#10
Ethem Akural, Voitto Järvimäki, Raija Korhonen, Hannu Kautiainen, Maija Haanpää
Background and purpose Pulsed radiofrequency (PRF) is widely used for the treatment of chronic pain, although its mechanism of action is not known. The evidence of efficacy of PRF for neuropathic pain (NP) conditions is limited. A double-blind, randomized, sham-controlled parallel study was conducted to evaluate the efficacy and safety of PRF in the treatment of peripheral posttraumatic NP. Methods Forty-five patients with peripheral posttraumatic NP in their upper or lower limb were randomly assigned to receive PRF or sham treatment to the injured peripheral nerve (s) causing peripheral posttraumatic NP...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913782/translational-animal-models-using-veterinary-patients-an-example-of-canine-osteoarthritis-oa
#11
Outi Vainio
Background and purpose The use of laboratory animals in pain research has powerfully contributed to our detailed understanding of the physiological mechanisms of pain. Animal models also represent an essential tool to screen and select novel drug molecules with potentially analgesic properties. Despite of the inevitable input of laboratory animal trials, recent studies have shown that animal pain models have repeatedly failed to predict clinical analgesic efficacy and adverse side effects of potential drug molecules in human pain patients...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913762/the-impact-of-chronic-pain-european-patients-perspective-over-12-months
#12
Tony O'Brien, Harald Breivik
Background and methods Pain Study Tracking Ongoing Responses for a Year (PainSTORY) is a longitudinal study generating some quantitative and limited qualitative data concerning the experiences of individual patients with non-malignant chronic pain. Research was conducted across 13 European countries and a total of 294 patients completed the full evaluation process over 12 months. Adult patients (>18 years old) scoring >4 on an 11-point numeric pain rating scale (NRS-11) for most days during an average week were eligible...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913746/neuroimaging-of-the-human-visceral-pain-system-a-methodological-review
#13
Jens Brøndum Frøkjær, Søren Schou Olesen, Carina Graversen, Trine Andresen, Dina Lelic, Asbjørn Mohr Drewes
During the last decades there has been a tremendous development of non-invasive methods for assessment of brain activity following visceral pain. Improved methods for neurophysiological and brain imaging techniques have vastly increased our understanding of the central processing of gastrointestinal sensation and pain in both healthy volunteers as well as in patients suffering from gastrointestinal disorders. The techniques used are functional magnetic resonance imaging (fMRI), positron emission tomography (PET), electroencephalography (EEG)/evoked brain potentials (EPs), magnetoencephalography (MEG), single photon emission computed tomography (SPECT), and the multimodal combinations of these techniques...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913704/cathepsin-s-is-increased-in-cerebrospinal-fluid-from-patients-with-neuropathic-pain-a-support-of-the-microglia-hypothesis-in-humans
#14
Torsten Gordh, Anne-Li Lind, Constantin Bodolea, Ellen Hewitt, Anders Larsson
Aims Cathepsin S has been reported to be a biomarker of spinal microglial activation, a process suggested to be involved in the pathophysiology of chronic neuropathic pain. So far this has been shown only in animal experiments. The aim of this study was to investigate the concentrations of cathepsin S in human cerebrospinal fluid (CSF) samples from a well-defined patient cohort suffering from neuropathic pain as compared to controls. Methods CSF samples from patients suffering from chronic neuropathic pain (n = 14) were analyzed for cathepsin S levels using commercial sandwich ELISAs (DY1183, R&D Systems, Minneapolis, MN, USA)...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913689/a-hybrid-emotion-focused-exposure-treatment-for-chronic-pain-a-feasibility-study
#15
Steven J Linton, Alan E Fruzzetti
Background and aims Exposure in vivo for patients with fear-related chronic pain has a strong theoretical base as well as empirical support. However, the treatment does not work for every patient and overall the effect size is only moderate, underscoring the need for improved treatments. One possible way forward might be to integrate an emotion regulation approach since emotions are potent during exposure and because distressing emotions may both interfere with exposure procedures and patient motivation to engage in exposure...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913684/depression-and-anxiety-in-adolescents-aggravate-abdominal-pain-and-abdominal-pain-deepens-depression-which-increases-suffering-from-chronic-pain
#16
EDITORIAL
Harald Breivik
No abstract text is available yet for this article.
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913683/psychosocial-aspects-of-everyday-life-with-chronic-musculoskeletal-pain-a-systematic-review
#17
Lotte Nygaard Andersen, Maria Kohberg, Birgit Juul-Kristensen, Lene Gram Herborg, Karen Søgaard, Kirsten Kaya Roessler
Background and objective Chronic pain is a growing phenomenon worldwide. It is considered a medical problem because, besides the socio-economic issues involved, pain is often accompanied by psychosocial problems. Apart from the physical pain, living with chronic pain has many additional consequences. People living with chronic pain generally suffer from other physical and psychological consequences. The impact of chronic pain varies enormously between individuals, but the suffering is frequently pervasive and detrimental...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913678/female-chronic-pelvic-pain-is-highly-prevalent-in-denmark-a-cross-sectional-population-based-study-with-randomly-selected-participants
#18
S Loving, T Thomsen, P Jaszczak, J Nordling
Background and purpose Female chronic pelvic pain is a significant clinical problem that burdens the health care services and work productivity, and leads to disability and reduced quality of life among the women affected. A recent systematic review reported worldwide prevalence rates for female chronic pelvic pain ranging from 2.1% to 24%. Our aim was to assess the prevalence, characteristics, and factors associated with chronic pelvic pain among women living in Denmark, and to compare these findings with a pain-free reference group...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913656/suicide-attempts-in-chronic-pain-patients-a-register-based-study
#19
Elsebeth Stenager, Erik Christiansen, Gitte Handberg, Børge Jensen
Background There are several studies about the relationship between depression and chronic non-malignant pain. These studies have shown that up to 50% of chronic pain patients are suffering from depression. It is, therefore, reasonable to expect that pain patients would also have an increased risk of suicidal behaviour. This problem is not well studied. Since 1990 the Centre for Suicide Research, Odense, Denmark has registered all suicide attempts in patients residing in the Region of Funen, Denmark. The Pain Clinic, Odense University Hospital receives patients with chronic pain from the entire Region of Southern Denmark...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913653/pain-and-other-symptoms-in-patients-with-chronic-benign-paroxysmal-positional-vertigo-bppv
#20
Wenche Iglebekk, Carsten Tjell, Peter Borenstein
Background and aim A diagnosis of chronic benign paroxysmal positional vertigo (BPPV) is based on brief attacks of rotatory vertigo and concomitant nystagmus elicited by rapid changes in head position relative to gravity. However, the clinical course of BPPV may vary considerably from a self-limiting to a persisting and/or recurrent disabling problem. The authors' experience is that the most common complaints of patients with chronic BPPV are nautical vertigo or dizziness with other symptoms including neck pain, headache, widespread musculoskeletal pain, fatigue, and visual disturbances...
December 29, 2017: Scandinavian Journal of Pain
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