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Lower digestive tract bleeding

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https://www.readbyqxmd.com/read/27894604/evaluation-of-the-efficacy-of-therapeutic-endoscopy-in-gastrointestinal-bleeding-secondary-to-angiodysplasias
#1
J Arribas Anta, C Zaera de la Fuente, R Martín Mateos, J A González Martín, A Cañete Ruiz, D Boixeda de Miquel, A Albillos Martínez
INTRODUCTION: Gastrointestinal angiodysplasias are defined as vascular dilations that communicate capillaries and veins in the walls of the digestive tract. The clinical presentation of these lesions varies from chronic occult bleeding to severe gastrointestinal hemorrhage. AIM: The primary aim of our study was to analyze lesion location, the efficacy of therapeutic endoscopy with argon plasma coagulation, and the factors associated with rebleeding in patients with gastrointestinal angiodysplasias...
November 25, 2016: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/27677116/ulcerated-choledochocele-a-case-report
#2
E Ray-Offor, S N Elenwo, P O Igwe, C Ngeribara
BACKGROUND: The cystic dilatation of the biliary tract is an uncommon anomaly. Choledochocele, a cystic dilatation of the distal common bile duct, rarely presents clinically as massive gastrointestinal bleeding. AIM: This is to report a very rare disease condition and highlight minimal access options in surgical care. CASE SUMMARY: A 13 year-old boy was referred with a day history of sudden onset of passage of bright red blood per rectum with a fainting episode...
September 13, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27622351/the-role-of-colonoscopy-in-the-diverticular-disease
#3
Giuseppe Grande, Claudio Zulli, Flavia Pigò, Maria E Riccioni, Francesco Di Mario, Rita L Conigliaro
Colonic diverticula are one of the most frequent conditions found during the endoscopic examination of the lower digestive tract, interestingly in >70% of people after 80 years old. Of them, only a few percentage develop complications such as acute diverticulitis or diverticular bleeding. Up to now, colonoscopy represents the most important diagnostic and therapeutic tool on the hands of the clinicians. On the basis of this the need for a standardized and reproducible approach is now emerging. This short review article is tasked to point out some open issues concerning the role of colonoscopy in diverticular disease...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27348725/meddra%C3%A2-automated-term-groupings-using-ontoadr-evaluation-with-upper-gastrointestinal-bleedings
#4
Julien Souvignet, Hadyl Asfari, Jérémy Lardon, Emilie Del Tedesco, Gunnar Declerck, Cédric Bousquet
OBJECTIVE: To propose a method to build customized sets of MedDRA terms for the description of a medical condition. We illustrate this method with upper gastrointestinal bleedings (UGIB). RESEARCH DESIGN AND METHODS: We created a broad list of MedDRA terms related to UGIB and defined a gold standard with the help of experts. MedDRA terms were formally described in a semantic resource named OntoADR. We report the use of two semantic queries that automatically select candidate terms for UGIB...
September 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/27188612/-prognostic-analysis-of-gastrointestinal-stromal-tumors-complicated-with-gastrointestinal-bleeding
#5
R T Li, G J Zhang, W H Fu, W D Li
OBJECTIVE: To study the relationship between clinicopathological characteristics, prognosis and gastrointestinal bleeding in primary gastrointestinal stromal tumors (GIST). METHODS: The clinicopathological and follow-up data of 200 patients with gastrointestinal stromal tumors treated in our hospital from April 2008 to December 2014 were retrospectively reviewed. The correlation of gastrointestinal bleeding with gastrointestinal stromal tumor clinicopathological characteristics and prognosis were analyzed...
May 23, 2016: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/25972676/a-sporadic-small-jejunal-gist-presenting-with-acute-lower-gastrointestinal-hemorrhage-a-review-of-the-literature-and-management-guidelines
#6
Sridar Govindaraj, Brendan Hermenigildo Dias, S L Gautham
Gastrointestinal stromal tumors (GISTs) represent the majority of primary nonepithelial neoplasms of the digestive tract, most frequently expressing the KIT protein detected by immunohistochemical staining for the CD117 antigen. Jejunal GISTs account for approximately 10 % of GISTs. Patients usually present with abdominal discomfort. Jejunal GISTs may cause symptoms secondary to obstruction or hemorrhage. Pressure necrosis and ulceration of the overlying mucosa may cause gastrointestinal bleeding, and patients who experience significant blood loss may suffer from malaise and fatigue...
April 2015: Indian Journal of Surgery
https://www.readbyqxmd.com/read/25838821/somatostatin-analogs-in-the-medical-management-of-occult-bleeding-of-the-lower-digestive-tract
#7
REVIEW
Julie Martin-Grace, Gianluca Tamagno
The management of occult bleeding from the lower digestive tract can be very challenging. In cases of identified angiodysplasia, the first line management options can be limited by a number of clinical or anatomical factors and an alternative approach might be required, including the use of medications. Somatostatin analogs have been considered as an effective and well-tolerated alternative management option in a number of cases where the endoscopic therapeutic approach is not practical or is unsuccessful, in patients with coagulopathies or who need concomitant anticoagulation or antiplatelet treatment...
2015: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/25607401/meckel-s-diverticulum-in-children-clinical-and-pathological-aspects
#8
Georgeta Ligia Stănescu, Iancu Emil Pleşea, Radu Diaconu, Cristian Gheonea, Corneliu Sabetay, Dalia Ţîştea, Elena Carmen Niculescu
Meckel's diverticulum (MD) represents one of the most common malformations of the digestive tract, being a vestige of the proximal end of omphalo-mesenteric duct, which normally obliterates and atrophiates between the sixth and ninth week of intrauterine life. It is estimated that 2-4% of people are carriers of this malformation. The interest in this organ study lies in the fact that it presents its own non-specific pathology, mimicking a cecal, colon or small intestine pathology. It seems that most MD cases are asymptomatic (AS MD), being arbitrary discovered during surgeries, whereas only a small part are being symptomatic (S MD)...
2014: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/25144351/ulcerative-ileitis-after-proctocolectomy-in-children-a-complication-of-ulcerative-colitis-or-a-disease-in-itself-after-ileoanal-pullthrough
#9
Alba Sánchez-Galán, Ane M Andres, Beatriz Fernández-Caamaño, Alejandra Vilanova, Eva Dominguez, Ruben Ortiz, Gerardo Prieto, Manuel Lopez-Santamaria, J A Tovar
Ulcerative ileitis (UI) after restorative proctocolectomy (RPC) and ileoanal pullthrough procedure (IAPP) is a rare condition described as inflammation of the terminal ileum proximal to the anastomosis. It is mostly observed in ulcerative colitis (UC) and is designated as prepouch ileitis; sometimes with pouchitis, but not necessarily all the time. Its incidence in adults is less than 5%, but the information in children is limited. Pathogenesis is unknown, it has been considered as a disease by itself, independently on the underlying disease...
February 2015: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/24744592/non-small-bowel-abnormalities-identified-during-small-bowel-capsule-endoscopy
#10
Reinier A Hoedemaker, Jessie Westerhof, Rinse K Weersma, Jan J Koornstra
AIM: To investigate the incidence of non-small-bowel abnormalities in patients referred for small bowel capsule endoscopy, this single center study was performed. METHODS: Small bowel capsule endoscopy is an accepted technique to investigate obscure gastrointestinal bleeding. This is defined as bleeding from the digestive tract that persists or recurs without an obvious etiology after a normal gastroduodenoscopy and colonoscopy. Nevertheless, capsule endoscopy sometimes reveals findings outside the small bowel, i...
April 14, 2014: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/24653853/blue-rubber-bleb-nevus-syndrome-as-a-cause-of-lower-digestive-bleeding
#11
Carlos Augusto Real Martinez, Murilo Rocha Rodrigues, Daniela Tiemi Sato, Paulo Pedroso Silveira Júnior, Rafael Fernandes Gama, Christian Bornia Mattavelli, José Aires Pereira
Introduction. Blue rubber bleb nevus syndrome is a rare disorder that is characterized by multiple recurrent vascular malformations that involve the skin and the gastrointestinal tract. The disease can present chronic anemia and severe episodes of gastrointestinal bleeding. Case Report. A 41-year-old man was admitted with recurrent episodes of lower gastrointestinal bleeding and anemia that had worsened over the last 3 months. The physical examination showed soft, diffuse, compressible, bluish nodules on all of the skin surfaces of the body...
2014: Case Reports in Surgery
https://www.readbyqxmd.com/read/24569136/-digestive-diseases-in-the-epistolary-collection-of-16th-century
#12
Francesc Devesa Jordà
Correspondence is an important source of documentation for studying health and, therefore, the gastrointestinal symptoms of diseases. We studied the gastrointestinal disease described in the Monumenta Borgia collection, which contains documents from the 16th century, mainly letters about Francis Borgia, the last great figure of a family originally from Valencia and with universal significance. Of the 2769 documents examined, 1231 (44.5%) contained some health-related descriptions and 42 items were related to gastrointestinal disease, representing 7...
June 2014: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/24503927/triflusal-and-aspirin-in-the-secondary-prevention-of-atherothrombotic-ischemic-stroke-a-very-long-term-follow-up
#13
RANDOMIZED CONTROLLED TRIAL
José Alvarez-Sabín, Manuel Quintana, Estevo Santamarina, Olga Maisterra
BACKGROUND: The mean follow-up in the clinical trials of antiplatelet drugs in the secondary prevention of ischemic atherothrombotic stroke ranges from 1 to 5.5 years. Thus, the safety and efficacy of these drugs in the very long term is not totally documented. We have assessed the safety and effectiveness of triflusal and aspirin for a very long-term period in the secondary prevention of patients with ischemic atherothrombotic stroke. METHODS: Patients with atherothrombotic ischemic stroke, including TIA, who participated in randomized clinical trials of triflusal versus aspirin were included in the study...
2014: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/24126426/ibandronate-associated-ischemic-colitis-case-report
#14
Sofia Vitor, Ana Nunes, Cristina Fonseca, João Freitas
Ibandronate is considered to be a safe drug, and the few reported side-effects in the digestive system are usually related to the upper gastrointestinal tract. Large bowel lesions associated to ibandronate use in humans have not been reported. We describe the case of a 52-year-old female with two episodes of lower abdominal pain after the intake of oral ibandronate. The second pain episode was followed by hematochezia with endoscopic and histological evidence of sigmoid ischemia. No other possible causes of colonic ischemia were found...
October 2012: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/24007933/-wiskott-aldrich-syndrome-associated-to-vasculitis-a-therapeutic-challenge
#15
Aidé Tamara Staines-Boon, Luis Alfredo Domínguez-Sansores, Luz María Sánchez-Sánchez, Mario Amaya-Guerra, Diana González-Cabello, Silvia Danielian
Wiskott Aldrich syndrome (WAS) is an X-linked primary immunodeficiency, associated with WASP gene mutation that causes severe immunological abnormalities and alterations in platelet function. A seven year old male patient with WASP, began with acute abdominal pain, fever and knee swelling. The diagnosis of septic arthritis was made, and he was treated with broad-spectrum antibiotics and human gammaglobulin. During treatment he presented digestive tract bleeding with hypovolemic shock; after 72 hours palpable purpura in upper and lower extremities appeared...
January 2012: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/23708295/the-future-of-capsule-endoscopy
#16
REVIEW
Jean-Francois Rey
Small-bowel capsule endoscopy (SBCE) was introduced 11 years ago by Given Imaging and is becoming the gold standard for small-bowel examination. This major step in the field of digestive medicine has opened the possibility of promising non-invasive explorations of the esophagus, stomach, and colon. SBCE can be used to overcome the inherent limitations of enteroscopy, especially in the West, where the capsule has been available since 2001. Obscure gastrointestinal (GI) bleeding with normal findings on upper and lower endoscopy remains the most important indication, and suspected Crohn's disease is also a well-accepted indication...
2013: Keio Journal of Medicine
https://www.readbyqxmd.com/read/23486520/nonsteroidal-anti-inflammatory-drug-use-is-associated-with-cancer-risk-reduction-in-chronic-dialysis-patients
#17
Shuo-Ming Ou, Yung-Tai Chen, Pei-Wen Chao, Yi-Jung Lee, Chia-Jen Liu, Chiu-Mei Yeh, Tzeng-Ji Chen, Tzen-Wen Chen, Wu-Chang Yang, Szu-Yuan Li
Previous studies have shown that nonsteroidal anti-inflammatory drug (NSAID) use might be associated with a lower risk of developing cancer in the general population. Patients on dialysis have increased risk for cancer, but there are no studies to determine the relationship between NSAID use and cancer risk in these patients. To identify any association between NSAID use and cancer risk in patients with end-stage renal disease on dialysis, we used Taiwan's National Health Insurance database to conduct a nationwide population-based, propensity score-matched cohort study...
July 2013: Kidney International
https://www.readbyqxmd.com/read/23306759/-use-of-argon-plasma-coagulation-in-digestive-endoscopy-a-concise-review
#18
REVIEW
M Zippi, G Traversa, A Cocco, R Pica, C Cassieri, E V Avallone, G Occhigrossi
Argon plasma coagulation (APC) is a non-contact thermal method of hemostasis that has generated much attention in recent years. This endoscopic procedure is used primarily to control bleeding from lesions in the gastrointestinal tract, and also sometimes to debulk tumours in the case of patients for whom surgery is not recommended. APC involves the use of a jet of ionized argon gas (plasma) that is directed through a probe passed through the endoscope. The probe is placed at some distance from the lesion, and tissue damage is limited to superficial layers...
November 2012: La Clinica Terapeutica
https://www.readbyqxmd.com/read/23197242/multiple-carcinoid-tumors-of-the-small-intestine-preoperatively-diagnosed-by-double-balloon-endoscopy
#19
Se-Yong Lee, Shibuya Tomoyoshi, Keiichi Haga, Hitosi Sasaki, Chie Ogata, Osamu Nomura, Yuka Fukuo, Wataru Abe, Taro Osada, Akihito Nagahara, Tatsuo Ogihara, Hirohiko Kamiyama, Kazuhiro Sakamoto, Sumio Watanabe
BACKGROUND: Multiple carcinoid tumors of the small intestine are rare and are very difficult to detect preoperatively. CASE REPORT: A 75-year-old woman in whom the bleeding focus could not be found by upper and lower endoscopy and abdominal CT was admitted for evaluation of anemia. We examined the patient with total double-balloon endoscopy (DBE) and located multiple submucosal tumors. The multiple carcinoid tumors were resected successfully under laparoscopy. CONCLUSIONS: We report a case of a successful laparoscopic operation for multiple carcinoid tumors in the small intestine without intraoperative endoscopy...
December 2012: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/23152321/anal-squamous-carcinoma-a-new-aids-defining-cancer-case-report-and-literature-review
#20
Marcelo Corti, María F Villafañe, Esteban Marona, Daniel Lewi
Squamous anal cell carcinoma is a rare malignancy that represents the 1.5% to 2% of all the lower digestive tract cancers. However, an increased incidence of invasive anal carcinoma is observed in HIV-seropositive population since the widespread of highly active antiretroviral therapy. Human papillomavirus is strongly associated with the pathogenesis of anal cancer. Anal intercourse and a high number of sexual partners appear to be risk factors to develop anal cancer in both sexes. Anal pain, bleeding and a palpable lesion in the anal canal are the most common clinical features...
December 2012: Revista do Instituto de Medicina Tropical de São Paulo
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