keyword
https://read.qxmd.com/read/37389671/thrombotic-microangiopathy-and-disseminated-intravascular-coagulation-in-a-patient-with-carcinomatosis-of-the-bone-marrow-due-to-gastric-adenocarcinoma-case-report
#21
JOURNAL ARTICLE
Gabriel Suarez-Reyes, Kateir Contreras, Fredy Alexander Avila-Almanza, Ana Janeth Salazar-Vargas, Camilo Molineros-Baron, Julian Serrano-Giraldo
Carcinomatosis of the bone marrow is a rare clinical condition characterized by diffuse tumor infiltration of the bone marrow accompanied by hematological abnormalities, including thrombotic microangiopathy (TMA) and disseminated intravascular coagulation (DIC). In patients with gastric carcinoma, this association is infrequent. Below we present a case of a 19-year-old female patient with no known pathological history who presented with upper digestive tract bleeding. Upon examination, anemia and thrombocytopenia were documented, with schistocytes in the peripheral blood smear and prolonged coagulation times...
June 30, 2023: Romanian Journal of Internal Medicine
https://read.qxmd.com/read/37253640/preclinical-study-of-a-novel-ingestible-bleeding-sensor-for-upper-gastrointestinal-bleeding
#22
JOURNAL ARTICLE
Kimberly F Schuster, Christopher C Thompson, Marvin Ryou
BACKGROUND/AIMS: Upper gastrointestinal bleeding (UGIB) is a life-threatening condition that necessitates early identification and intervention and is associated with substantial morbidity, mortality, and socioeconomic burden. However, several diagnostic challenges remain regarding risk stratification and the optimal timing of endoscopy. The PillSense System is a noninvasive device developed to detect blood in patients with UGIB in real time. This study aimed to assess the safety and performance characteristics of PillSense using a simulated bleeding model...
May 31, 2023: Clinical Endoscopy
https://read.qxmd.com/read/37248086/-a-case-of-corrosive-digestive-tract-and-lung-injury-caused-by-ingestion-of-pipeline-dredging-agent
#23
JOURNAL ARTICLE
B B Wang, J X Wang, H G Chen, R J Yang
Ingestion of corrosive substances can severely burn the upper digestive tract leading to bleeding or perforation, and may even be life-threatening. Less commonly, damage to the trachea and bronchi is involved. In this paper, a case of corrosive digestive tract injury and lung injury after oral administration of pipeline dredging agent (the main components are hydroxide, sodium carbonate, sodium hypochlorite, etc.) was analyzed. After active rescue treatment, the patient died of massive hemoptysis. It is suggested that serious complications may occur after ingestion of corrosive substances...
May 20, 2023: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://read.qxmd.com/read/37193446/to-bleed-or-not-to-bleed
#24
Peter A Iskander, Syed Muhammad Hussain Zaidi, Jiayi Zheng, Anthony Iskander, Mark M Aloysius, Vikas Khurana, Simin Nasr
The location of gastrointestinal (GI) bleeding can be characterized based on the characteristics of the bowel movements these patients present with. Bright red blood per rectum is usually associated with a lower bleed; if brisk and significant enough, however, upper bleeds can present similarly. Melenic or "tar-colored" bowel movements are more likely to occur from upper bleeds as the color is secondary to digestion of hemoglobin as it passes through the GI tract. At times, there can be a mix of the two which can make a clinical decision for intervention less obvious...
April 2023: Curēus
https://read.qxmd.com/read/37165534/a-practical-approach-for-small-bowel-bleeding
#25
REVIEW
Sung Eun Kim, Hyun Jin Kim, Myeongseok Koh, Min Cheol Kim, Joon Sung Kim, Ji Hyung Nam, Young Kwan Cho, A Reum Choe
Gastrointestinal (GI) bleeding is one of the most common conditions among patients visiting emergency departments in Korea. GI bleeding is divided into upper and lower GI bleeding, according to the bleeding site. GI bleeding is also divided into overt and occult GI bleeding based on bleeding characteristics. In addition, obscure GI bleeding refers to recurrent or persistent GI bleeding from a source that cannot be identified after esophagogastroduodenoscopy or colonoscopy. The small intestine is the largest part of the alimentary tract...
May 2023: Clinical Endoscopy
https://read.qxmd.com/read/37084302/transgastric-laparoscopic-polypectomy-in-giant-gastric-polyps-not-susceptible-of-endoscopic-management-novel-surgical-technique-and-case-series
#26
JOURNAL ARTICLE
Felipe Cabrera, Felipe Bernal, Ricardo Villarreal, Jean Pulido, Mauricio Pedraza, Sebastian Sánchez, Laura T Padilla-Pinzon, María A Pineda
BACKGROUND: The identification of gastric polyps incidentally in endoscopies of the upper digestive tract has increased its incidence, varying between 0.5% and 23%. 10% of these polyps have symptoms, 40% are hyperplastic. We allow ourselves to propose a laparoscopic technique for the management of giant hyperplastic polyps associated with a pyloric syndrome, not susceptible to endoscopic resection. METHOD: A series of patients approached by laparoscopic transgastric polypectomy due to the giant gastric polyps associated with pyloric syndrome, in Bogotá, Colombia, from January 2015 to December 2018...
2023: Cirugia y Cirujanos
https://read.qxmd.com/read/37072314/-risk-factors-for-complications-of-endoscopic-full-thickness-resection-of-upper-gastrointestinal-submucosal-tumors
#27
JOURNAL ARTICLE
L J Ni, W X Zhu, C T Zou, G T Xu, C Wang, A R Wu
Objective: To analyze the risk factors for complications of endoscopic full-thickness resection (EFTR) of upper gastrointestinal submucosal tumors (SMTs). Methods: This was a retrospective observational study. The indications for EFTR included: (1) SMTs originating from the muscularis propria layer and growing out of the cavity or infiltrating the deep part of the muscularis propria layer; (2) SMTs diameter <5 cm; and (3) tumor identified as closely adherent to the serous layer during endoscopic submucosal dissection or endoscopic mucosal resection...
April 25, 2023: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/37008525/endoscopic-submucosal-dissection-for-subepithelial-tumor-treatment-in-the-upper-digestive-tract-a-western-multicenter-study
#28
JOURNAL ARTICLE
Raffaele Manta, Francesco Paolo Zito, Francesco Pugliese, Angelo Caruso, Santi Mangiafico, Alessandra D'Alessandro, Danilo Castellani, Ugo Germani, Massimiliano Mutignani, Rita Luisa Conigliaro, Luca Reggiani Bonetti, Takahisa Matsuda, Vincenzo De Francesco, Angelo Zullo, Giuseppe Galloro
BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) has been proposed for removal of gastrointestinal subepithelial tumors (GI-SETs), but data are still scanty. This study aimed to report a case series from a western country. PATIENTS AND METHODS: Data of patients with upper GI-SETs suitable for ESD removal observed in 4 centers were retrospectively reviewed. Before endoscopic procedure, the lesion was characterized by endosonographic evaluation, histology, and CT scan...
March 2023: GE Portuguese Journal of Gastroenterology
https://read.qxmd.com/read/36976599/medical-malpractice-and-diagnostic-errors-in-japanese-emergency-departments
#29
JOURNAL ARTICLE
Taiju Miyagami, Takashi Watari, Taku Harada, Toshio Naito
INTRODUCTION: Emergency departments (ED) are unpredictable and prone to diagnostic errors. In addition, non-emergency specialists often provide emergency care in Japan due to a lack of certified emergency specialists, making diagnostic errors and associated medical malpractice more likely. While several studies have investigated the medical malpractice related to diagnostic errors in EDs, only a few have focused on the conditions in Japan. This study examines diagnostic error-related medical malpractice lawsuits in Japanese EDs to understand how various factors contribute to diagnostic errors...
February 20, 2023: Western Journal of Emergency Medicine
https://read.qxmd.com/read/36713281/undifferentiated-carcinoma-with-osteoclast-like-giant-cells-a-rare-cause-of-upper-gastrointestinal-bleeding
#30
Sofia Ventura, Pedro Rodrigues, Eugénia Cancela, Ana Catarina Carvalho, Cláudio Rodrigues, Ângela Domingues, Juliana Pinho, Diana Martins, Américo Silva
Undifferentiated osteoclast-like giant cell carcinomas (UOLGCCs) of the digestive tract are very rare, with only a few cases reported in the literature. An 82-year-old man was referred to the emergency department for melena. Endoscopic examination revealed a hemicircumferential ulcerovegetative lesion, involving the bulbar apex and extending to the second portion of the duodenum; biopsies revealed an UOLGCC. The patient underwent transfusion support therapy, and he was proposed for best supportive care. Duodenal UOLGCC is an extremely rare cause of upper gastrointestinal bleeding...
January 2023: ACG Case Reports Journal
https://read.qxmd.com/read/36562527/multiple-lymphomatous-polyposis-rectal-prolapse-as-an-atypical-presentation-of-the-disease
#31
JOURNAL ARTICLE
Fernando García Villarreal, Paola Jaqueline Bran Alvarado, Grecia Celis-Valenzuela, María Fernanda Castillo Martínez, José Luis Herrera Elizondo, Sofía Rodríguez Jacobo, Aldo Azael Garza Galindo, Joel Omar Jáquez-Quintana
Multiple lymphomatous polyposis is a rare entity that can involve different types of both B-cell and T-cell lymphomas, including mantle cell lymphoma. A 57-year-old male patient is presented with prolapse of the rectal canal associated with data of lower digestive tract bleeding. A colonoscopy and subsequent upper endoscopy were performed with findings compatible with lymphomatous polyposis. After a biopsy study, mantle cell lymphoma was diagnosed and chemotherapy treatment was started. The endoscopic finding of multiple lymphomatous polypoposis associated with an adequate histopathological diagnosis improves the treatment success rate in patients with different types of gastrointestinal lymphomas...
December 23, 2022: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/36525139/safety-of-direct-oral-anticoagulants-in-patients-with-advanced-solid-tumors-receiving-anti-vegf-agents-a-retrospective-study
#32
JOURNAL ARTICLE
Alice Boileve, Laurence Albiges, Michel Ducreux, Eric Baudin, Alexandra Leary, Benjamin Besse, Julien Hadoux, David Malka, André Rieutord, Florian Scotté, Amandine Maulard, Olivier Mir
PURPOSE: Kinase inhibitors (KI) and antibodies targeting the VEGF pathway are approved in a broad spectrum of cancers and associated with an increased risk of bleeding and thromboembolic events (TE). The use of direct oral anticoagulants (DOACs) apixaban and rivaroxaban is increasing in cancer patients, but limited data are available for patients receiving anti-VEGF agents. METHODS: To assess safety of DOAC with concomitant anti-VEGF agents, a retrospective chart review of all patients receiving concomitantly DOAC and anti-VEGF agents was performed from 2013 to 2020 in our center...
December 16, 2022: Supportive Care in Cancer
https://read.qxmd.com/read/36514851/prevalence-and-prognostic-significance-of-vitamin-c-deficiency-in-patients-with-acute-upper-gastrointestinal-bleeding-a%C3%A2-prospective-cohort-study
#33
JOURNAL ARTICLE
Samuel Hui, Andy Lim, Elaine Koh, Joshua Abasszade, Aparna Morgan, Pei Y Tan, Christopher Lemoh, Marcus Robertson
BACKGROUND: Vitamin C is an essential dietary nutrient important for collagen synthesis, including within the gastrointestinal tract. AIM: We aimed to document the prevalence of Vitamin C deficiency (VCD) in patients who present with upper gastrointestinal bleeding (UGIB) and its association with clinical outcomes. METHODS: We conducted a prospective cohort study of patients presenting with UGIB. Fasting Vitamin C levels were collected at admission...
December 13, 2022: Alimentary Pharmacology & Therapeutics
https://read.qxmd.com/read/36510773/hemostatic-effect-and-mechanism-of-epidermal-growth-factor-hemostatic-powder-after-endoscopic-submucosal-dissection-in-a-porcine-model
#34
JOURNAL ARTICLE
Da Hyun Jung, Ji Hyun Youn, Bo Mi Moon, Ji Hye Lee, Hyun-Seung Ryu, Joon Sung Kim, Hyuk Lee, Gwang Ha Kim, Jun Chul Park
BACKGROUND/AIMS: Among several methods used to prevent endoscopic submucosal dissection (ESD) bleeding, the recently developed hemostatic powder (HP) has few technical limitations and is relatively easy-to-use. This study aimed to analyze the hemostatic effects and mechanisms of two HPs using a porcine upper gastrointestinal hemorrhage model. METHODS: We evaluated HPs (Endospray and epidermal growth factor [EGF]-endospray) for adhesion, waterproofing ability, permeability, and absorption in vitro ...
December 13, 2022: Gut and Liver
https://read.qxmd.com/read/36276848/early-identification-of-high-risk-factors-for-upper-gastrointestinal-bleeding
#35
JOURNAL ARTICLE
Xuesong Jin, Xiaohong Wang, Pengfei Mao
OBJECTIVE: To identify simple and accurate pre-endoscopy risk factors for early identification of high-risk upper gastrointestinal bleeding. METHODS: Patients who were admitted to Suzhou Hospital of Integrated Traditional Chinese and Western Medicine from January 1, 2016, to December 31, 2019, due to upper gastrointestinal bleeding were retrieved, and the detailed clinical data of the above patients were collected. Patients with a definite diagnosis of bleeding from esophageal/and gastric varices were assigned to the high-risk group...
2022: Evidence-based Complementary and Alternative Medicine: ECAM
https://read.qxmd.com/read/36240492/upper-digestive-tract-bleeding-as-presentation-of-diffuse-large-b-cell-lymphoma1
#36
JOURNAL ARTICLE
Gabriela Reis, Joana Nunes, Nélia Gaspar, Susana Teixeira, Maria do Céu Espinheira, Eunice Trindade
No abstract text is available yet for this article.
October 14, 2022: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/36148665/a-window-in-the-duodenal-bulb-an-atypical-presentation-of-chronic-cholecystitis
#37
JOURNAL ARTICLE
André Mascarenhas, Liliana Carvalho, Ana Rita Franco, Raquel Mendes, Pedro Barreiro
A 74-year-old male presented with melena and fatigue, without fever or abdominal pain. Laboratory examination revealed anemia, leukocytosis, elevated C-reactive protein levels and conjugated hyperbilirubinemia with elevated liver enzymes. Upper endoscopy identified blood in the stomach and duodenum and a 6 mm hole in the anterosuperior surface of the duodenal bulb with spontaneous drainage of a bloody brownish content. The mucosa surrounding the hole was normal and there was a discrete mucosal flap that throbbed with air insufflation...
September 23, 2022: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/35846966/selection-of-digestive-tract-reconstruction-after-partial-gastric-sparing-surgery-in-patients-with-adenocarcinoma-of-the-esophagogastric-junction-of-ct-2-t-3-stage
#38
JOURNAL ARTICLE
Junli Zhang, Xijie Zhang, Sen Li, Chenyu Liu, Yanghui Cao, Pengfei Ma, Zhenyu Li, Zhi Li, Yuzhou Zhao
Objective: To investigate the appropriate reconstruction method of the digestive tract after partial gastric sparing surgery for adenocarcinoma of the esophagogastric junction of stage cT2 -T3 . Methods: A retrospective analysis of the clinical data of patients with adenocarcinoma of the esophagogastric junction from January 2015 to January 2019 in the General Surgery Department of Zhengzhou University Affiliated Tumor Hospital was performed. Patients with intraoperative double tract anastomosis composed the double tract reconstruction (DTR) group, and patients with intraoperative oesophagogastrostomy with a narrow gastric conduit group composed the oesophagogastrostomy by a narrow gastric conduit (ENGC) group...
2022: Frontiers in Surgery
https://read.qxmd.com/read/35801787/a-sewing-needle-in-the-liver-in-children-a-case-report-and-literature-review
#39
REVIEW
Huiwu Xing, Bingqian Tan, Chenyu Yang, Mingman Zhang
RATIONALE: In clinical practice, foreign bodies (FBs) in the digestive tract are more common in children, but intrahepatic FBs are rare, especially those that can cause infection, bleeding, bile leakage, and other complications. However, there is no consensus on its diagnosis and treatment due to the lack of large-scale cohort studies. PATIENT CONCERNS: Case 1 is a 4-years 8-months-old girl, who at the age of 10 months, showed an X-ray finding of a striped FB in her liver, with no symptoms...
July 8, 2022: Medicine (Baltimore)
https://read.qxmd.com/read/35764547/-clinical-characteristics-of-500-hospitalized-patients-with-liver-cirrhosis-a-retrospective-analysis-from-a-tertiary-hospital-in-beijing
#40
JOURNAL ARTICLE
J H Xu, Y N Fan, T T Ji, R Y Liang, Y Y Yu
Objective: To understand the clinical characteristics of hospitalized patients with liver cirrhosis, so as to provide theoretical basis for disease diagnosis and treatment, formulation of intervention measures, and improve the level of disease diagnosis and treatment. Methods: Hospitalized patients who were initially diagnosed with liver cirrhosis at Peking University First Hospital from August 2017 to December 2018 were selected retrospectively as the research objects. Liver cirrhosis demographic data, etiology, severity classification, incidence of complications, diagnosis and prognosis were recorded...
May 20, 2022: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
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