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Low digestive tract bleeding

Ke-Ling Wang, Shu-Fang Ma, Ling-Yu Pang, Meng-Na Zhang, Lin-Yan Hu, Meng-Jia Liu, Li-Ping Zou
RATIONALE: Blue rubber bleb nevus syndrome (BRBNS) is a rare disease characterized by multiple venous malformations. The gastrointestinal bleeding and secondary iron deficiency anemia are the most common complications. There are currently no effective treatments for BRBNS. Here, we report a case of successful treatment with a small dose of sirolimus of a BRBN patient with a de novo gene mutation. PATIENT CONCERNS: A 12-year-old female was admitted to our hospital with multiple hemangiomas for 12 years...
February 2018: Medicine (Baltimore)
Ding-Yun Liu, Tao Gan, Ni-Ni Rao, Yao-Wen Xing, Jie Zheng, Sang Li, Cheng-Si Luo, Zhong-Jun Zhou, Yong-Li Wan
The gastrointestinal endoscopy in this study refers to conventional gastroscopy and wireless capsule endoscopy (WCE). Both of these techniques produce a large number of images in each diagnosis. The lesion detection done by hand from the images above is time consuming and inaccurate. This study designed a new computer-aided method to detect lesion images. We initially designed an algorithm named joint diagonalisation principal component analysis (JDPCA), in which there are no approximation, iteration or inverting procedures...
August 2016: Medical Image Analysis
Mario Rodriguez-Lopez, Rosalía Velasco-López, Sara Mambrilla-Herrero, Martin Bailon-Cuadrado, Katherine T Plua, Luis M Diez-González, Jose I Blanco-Álvarez, Enrique Asensio-Díaz, Marta Gonzalo-Martín, Baltasar Pérez-Saborido, Jose L Marcos-Rodríguez
Testicular germ cell tumors, though rare (1%), represent the most common neoplasm among young men. Gastrointestinal involvement from these malignancies usually presents as bowel obstruction and digestive bleeding, but their frequency is low (5%). The patterns of this involvement are: infiltration from affected retroperitoneal lymph nodes or, less frequently, by peritoneal seeding and direct hematogenous spread. Particularly, infiltration of duodenum is also rare, though its real frequency is not well defined...
October 2015: Revista Española de Enfermedades Digestivas
B East, J Hoch
INTRODUCTION: Patients with signs of acute bleeding into the gastrointestinal tract are hospitalized at intensive care units of surgical departments for organizational reasons. There is a growing proportion of those treated with various forms of antithrombotic therapy. From the onset of endoscopic methods of haemostasis, mortality is low and surgical treatment of these patients is rarely required. Their treatment takes up a lot of human and financial resources. The question remains, whether it would be possible to stop the volume growth or even reduce the number of these patients...
July 2015: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
Mario Rodríguez López, Rosalía Velasco López, Sara Mambrilla Herrero, Martin Bailon Cuadrado, Katherine T Plua, Luis M Díez González, Jose I Blanco Álvarez, Enrique Asensio Díaz, Marta Gonzalo Martín, Baltasar Pérez Saborido, Jose L Marcos Rodríguez
Testicular germ cell tumors, though rare (1%), represent the most common neoplasm among young men. Gastrointestinal involvement from these malignancies usually presents as bowel obstruction and digestive bleeding, but their frequency is low (5%). The patterns of this involvement are: infiltration from affected retroperitoneal lymph nodes or, less frequently, by peritoneal seeding and direct hematogenous spread. Particularly, infiltration of duodenum is also rare, though its real frequency is not well defined...
July 14, 2015: Revista Española de Enfermedades Digestivas
Guoqin Yu, Bruce A Dye, Mitchell H Gail, Jianxin Shi, Vanja Klepac-Ceraj, Bruce J Paster, Guo-Qing Wang, Wen-Qiang Wei, Jin-Hu Fan, You-Lin Qiao, Sanford M Dawsey, Neal D Freedman, Christian C Abnet
BACKGROUND: Bacteria affect oral health, but few studies have systematically examined the role of bacterial communities in oral diseases. We examined this relationship in a large population-based Chinese cancer screening cohort. METHODS: Human Oral Microbe Identification Microarrays were used to test for the presence of 272 human oral bacterial species (97 genera) in upper digestive tract (UDT) samples collected from 659 participants. Oral health was assessed using US NHANES (National Health and Nutrition Examination Survey) protocols...
2014: BMC Public Health
Xiaochuan Guo, Zhiyuan Mao, Dan Su, Zhaocai Jiang, Li Bai
The aim of the study was to describe and analyze the clinicopathological features and diagnosis of Chinese patients with small intestine primary malignant tumors and to explore the best therapy to small bowel adenocarcinoma (SBA). More than 26,000 patients with digestive tract malignant tumors received treatment in PLA hospital from 2000 to 2011, and among them, there were 887 patients who had small intestine primary malignant tumors, and 666 of 887 patients had the completed basic clinical documents. We retrospectively analyzed the correlation between clinical and pathological features of the 666 patients and analyzed the survival and prognosis of 173 SBA patients with follow-up data...
April 2014: Medical Oncology
Harald Farnik, Jochen Weigt, Peter Malfertheiner, Angela Grützmann, Liebwin Gossner, Mireen Friedrich-Rust, Stefan Zeuzem, Christoph Sarrazin, Jörg G Albert
BACKGROUND AND STUDY AIMS: Direct retrograde cholangioscopy (DRC) may improve the diagnostic and therapeutic yield of endoscopic retrograde cholangiography (ERC) but safety, feasibility, and outcome are unknown. PATIENTS AND METHODS: All consecutive patients who underwent DRC at three tertiary endoscopy centers for inconclusive findings at ERC were included in this retrospective analysis. Ultraslim endoscopes (FujiFilm EG 530NP; Olympus GIF XP180; GIF N180) were used by the peroral route for intubating all accessible bile ducts...
January 2014: Endoscopy
Shuntaro Yoshida, Hirotsugu Watabe, Hiroyuki Isayama, Hirofumi Kogure, Yousuke Nakai, Natsuyo Yamamoto, Takashi Sasaki, Kazumichi Kawakubo, Tsuyoshi Hamada, Yukiko Ito, Yoko Yashima, Naoki Sasahira, Kenji Hirano, Yutaka Yamaji, Minoru Tada, Masao Omata, Kazuhiko Koike
AIM: Stent migration due to peristalsis of the colon is one of the unresolved complications of colonic self-expandable metallic stent (SEMS) placement. Axial force (AF), a recovery force of the stent to a straight position after bending, has been considered a factor influencing the conformability of the digestive tract. An uncovered SEMS (Niti-S Enteral Colonic Uncovered Stent, D-type; Taewoong, Inc., Gimpo, South Korea) with improved conformability is considered to decrease migration...
March 2013: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Z Adam, L Pour, M Krejčí, L Zahradová, P Szturz, R Koukalová, Z Rehák, T Nebeský, R Hájek, Z Král, J Mayer
UNLABELLED: Lenalidomide has been licenced for the treatment of multiple myeloma and, in 2012, it is used as a standard treatment of relapses of the disease. Literature contains a number of publications on the effects of lenalidomide in myelodysplastic syndrome, in malignant lymphomas and chronic B lymphocytic leukaemia. The effects of the drug in rare diseases, however, have not been investigated so far. In this paper, we summarize our experience with lenalidomide in rare blood disorders...
November 2012: Vnitr̆ní Lékar̆ství
Zhankun He, Chao Sun, Zhongqing Zheng, Qingxiang Yu, Tao Wang, Xin Chen, Hailong Cao, Wentian Liu, Bangmao Wang
BACKGROUND AND AIM: Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the digestive tract with potential for malignant transformation, are mainly treated by open surgery or laparoscopic resection. The aim of this retrospective study was to evaluate the clinical efficacy, safety, and feasibility of endoscopic submucosal dissection (ESD) for large-size (2-5 cm) GISTs in the esophagus and stomach. METHODS: A total of 31 patients with large-size GISTs in the esophagus (6 patients) and stomach (25 patients) underwent ESD between September 2008 and December 2011...
February 2013: Journal of Gastroenterology and Hepatology
Ling-Ling Zhu, Ling-Cheng Xu, Yan Chen, Quan Zhou, Su Zeng
AIM: To investigate prescribing pattern in low-dose aspirin users and physician awareness of preventing aspirin-induced gastrointestinal (GI) injury with combined protective medications. METHODS: A retrospective drug utilization study was conducted in the 2nd Affiliated Hospital, School of Medicine, Zhejiang University. The hospital has 2300 beds and 2.5 million outpatient visits annually. Data mining was performed on all aspirin prescriptions for outpatients and emergency patients admitted in 2011...
June 28, 2012: World Journal of Gastroenterology: WJG
Z Adam, L Pour, M Matýšková, M Krejčí, M Tomíška, P Szturz, Z Rehák, R Koukalová, L Křikavová, T Nebeský, C Neuman, M Navrátil, R Hájek, Z Král, J Mayer
BACKGROUND: Multiple angiomatosis is a rare disease with angiomatous formations in multiple organs and tissues and associated with a risk of fatal bleeding. CASE DESCRIPTION: In this patient, the bones, pleural and peritoneal cavities and digestive tract were involved. The patient had long-term been administered zoledronate that provided relief from bone pain as early as after the second dose. The effect of antiangiogenics was evaluated on CT and MRI. Since angiomatous proliferation is associated with chronic disseminated intravascular coagulation (DIC) and anaemisation, blood count and fibrinogen as well as D-dimer and soluble fibrin monomer concentrations are also used to assess treatment response...
February 2012: Vnitr̆ní Lékar̆ství
Hichem Jerraya, Amine Bousslema, Foued Frikha, Chadli Dziri
BACKGROUND: Upper gastrointestinal bleeding is a frequent cause for emergency hospital admission. Most severity scores include in their computation the endoscopic findings. The Glasgow-Blatchford score is a validated score that is easy to calculate based on simple clinical and biological variables that can identify patients with a low or a high risk of needing a therapeutic (interventional endoscopy, surgery and/ or transfusions). AIM: To validate retrospectively the Glasgow-Blatchford Score (GBS)...
December 2011: La Tunisie Médicale
Francesco Manguso, Elisabetta Riccio, Germana de Nucci, Maria Luisa Aiezza, Gerardino Amato, Linda Degl'Innocenti, Maria Maddalena Piccirillo, Gianfranco De Dominicis, Tara Santoro, Elena Trimarco, Antonio Balzano
AIM: To establish the prevalence of Helicobacter pylori (H. pylori) infection in patients with a bleeding peptic ulcer after consumption of non-steroidal antiinflammatory drugs (NSAIDs). METHODS: A very early upper endoscopy was performed to find the source of upper gastrointestinal bleeding and to take biopsy specimens for analysis of H. pylori infection by the rapid urease (CLO) test, histological examination, and bacterial culture. IgG anti-CagA were also sought...
October 28, 2011: World Journal of Gastroenterology: WJG
Zhi-dong Ye, Peng Liu, Fei Wang, Fan Lin, Yu-guang Yang, Song-yi Qian
OBJECTIVE: To evaluate the clinical outcome of surgical venous thrombectomy and simultaneous stenting in patients with acute, symptomatic iliofemoral deep venous thrombosis (DVT). METHODS: From October 2008 to December 2010, a total of 15 patients with acute symptomatic DVT underwent combined surgical venous thrombectomy and endovascular stenting in ipsilateral iliac vein. There were 6 male and 9 female patients, with a mean age of 57.4 years (ranging from 36 to 71 years)...
June 1, 2011: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
M Ramírez, J C López Gutiérrez, M Diaz, C Soto, M Miguel, C A de la Torre Ramos, S Barrena, Z Ros, J A Tovar
INTRODUCTION/AIMS: Bean or Blue Rubber Bleb Nevus Syndrome (BRBNS) is an uncommon disease characterized by multifocal venous malformations that predominantly affect the skin, soft tissues and gastrointestinal tract. Our objective is to familiarize the pediatric surgeon with this condition, promoting early diagnosis and seriated surgical treatment as therapeutic options. We have reviewed the diagnosis and treatment of 6 patients treated from 1993 to 2009. MATERIAL AND METHODS: All the patients had a venous malformation (> 10 cm) that acted as a marker...
October 2010: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
Fernando Barreda Bolaños, Humberto Liu Bejarano, Juvenal Sánchez Lihon, Italo Landeo Aliaga, Ziliany Sánchez Rodríguez
INTRODUCTION: The gastrointestinal stromal tumor (GIST) is the designation for a specific type of mesenchymal tumor of the digestive tract that is origin in the interstitial cells of Cajal (ICC) or its precursor multipotentials, its presentation is rare and therefore its best knowledge must affect a proper diagnosis and treatment. OBJECTIVES: To evaluate the clinical characteristics and to identify factors influencing survival of patients with gastrointestinal stromal tumor...
October 2010: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
E Târcoveanu, G Dimofte, A Vasilescu, C Bradea, D Ferariu
UNLABELLED: Gastrointestinal stromal tumours (GISTs) represent the most common non-epithelial tumour of the digestive tract. Laparoscopic approach may be considered ideal for the resection of these tumours. Their particular biological behaviour allows for a curative resection even without large resection margins and extensive lymphadenectomies. METHOD: Over a period of five years, eight patients benefited from laparoscopic resections (six patients with primary gastric GIST and two patients with small bowel GIST)...
May 2010: Acta Chirurgica Belgica
Moshe Rubin, Syed A Hussain, Albert Shalomov, Rafael A Cortes, Michael S Smith, Sang H Kim
BACKGROUND: Risk stratification of patients with acute upper GI bleeding (UGIB) in the emergency room (ER) enables appropriate triage to urgent endoscopy and therapeutic intervention. AIM: The aim of this study was to evaluate the ability of Live View Video Capsule Endoscopy (VCE) with Pillcam Eso(®) to accurately identify high and low risk patients with UGIB. METHODS: Twenty-four patients with a history of UGIB within 48 h of admission to the ER were randomized to VCE versus standard clinical assessment...
March 2011: Digestive Diseases and Sciences
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