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https://www.readbyqxmd.com/read/28214397/a-case-of-iv-degree-on-acute-radiation-dermatitis-in-china
#1
Zhen Shen, Ya-Hong Chen, Yue Chen, Yan Chen, Zhe Lv, Hai-Cheng Gao
This report investigates the nursing procedure of a case of adjuvant therapy of rectal cancer on IV degree of acute radiation dermatitis patients in the penis and scrotum junction. The lesion degree gradually increased. Fixation of the dressing was difficult in the penis and scrotum junction. The concept of wet healing with new dressings was used in patient. The silver ion dressings were used in inhibiting infection, and the wound was covered by the rimmed foam dressings. When it comes to the shaping period, water gel transparent paste was applied instead to cover the wound...
February 2, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28211272/effects-of-dimethyloxalylglycine-embedded-poly-%C3%AE%C2%B5-caprolactone-fiber-meshes-on-wound-healing-in-diabetic-rats
#2
Qiankun Zhang, Joung-Hwan Oh, Chan Ho Park, Jeong-Hwa Baek, Hyun-Mo Ryoo, Kyung Mi Woo
Impaired wound healing in diabetic patients is associated with altered inflammatory responses, poor angiogenesis, deficient extracellular matrix (ECM) component, and peripheral neuropathy. To develop a wound dressing that is capable of the controlled delivery of bioactive small molecules that can improve diabetic wound healing, dimethyloxalylglycine (DMOG)-embedded poly(ε-caprolactone) (PCL) fiber (PCLF/DMOG) meshes are fabricated by electrospinning, and the effects of the PCLF/DMOG meshes on wound healing in diabetic rats are evaluated...
February 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28210450/repercussions-of-intraalveolar-placement-of-combination-of-0-2-chlorhexidine-10-mg-metronidazole-gel-on-the-occurrence-of-dry-sockets-a-randomized-control-trial
#3
Jasleen Kaur, Rushik Raval, Anupam Bansal, Vinod Kumawat
BACKGROUND: To evaluate the effects of intraalveolar placement of gel containing 0.2% chlorhexidine and 10gm of metronidazole on the incidence of alveolar osteitis. MATERIAL AND METHODS: A total of 300 impacted third molars were extracted in 150 patients enrolled in this trial. In each subject a socket was randomly selected and packed to the crest of alveolar ridge with the gel. The contralateral socket was packed with placebo dressing. The occurrence of dry socket was assessed during 3rd and 5th postoperative days ...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28207633/acute-liver-failure-injury-related-to-drug-reaction-with-eosinophilia-and-systemic-symptoms-outcomes-and-prognostic-factors
#4
Philippe Ichai, Astrid Laurent-Bellue, Faouzi Saliba, David Moreau, Camille Besch, Claire Francoz, Laurence Valeyrie-Allanore, Sylvie Roussin Bretagne, Marc Boudon, Teresa Maria Antonini, Florent Artru, Gabriella Pittau, Olivier Roux, Daniel Azoulay, Eric Levesque, François Durand, Catherine Guettier, Didier Samuel
BACKGROUND: Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) is a rare severe adverse drug induced reaction with multiorgan involvement. The outcome and prediction of those patients who develop severe acute liver injury (sALI) or acute liver failure (ALF) remain little known. METHODS: A multicenter retrospective study of patients admitted with a diagnosis of DRESS-related sALI or ALF. Histological review was performed on liver core biopsies from native livers...
February 15, 2017: Transplantation
https://www.readbyqxmd.com/read/28203363/an-exploratory-factor-analysis-of-the-spontaneous-reporting-of-severe-cutaneous-adverse-reactions
#5
Manfred Hauben, Eric Hung, Wen-Yaw Hsieh
BACKGROUND: Severe cutaneous adverse reactions (SCARs) are prominent in pharmacovigilance (PhV). They have some commonalities such as nonimmediate nature and T-cell mediation and rare overlap syndromes have been documented, most commonly involving acute generalized exanthematous pustulosis (AGEP) and drug rash with eosinophilia and systemic symptoms (DRESS), and DRESS and toxic epidermal necrolysis (TEN). However, they display diverse clinical phenotypes and variations in specific T-cell immune response profiles, plus some specific genotype-phenotype associations...
January 2017: Therapeutic Advances in Drug Safety
https://www.readbyqxmd.com/read/28199744/buccal-films-as-a-dressing-for-the-treatment-of-aphthous-lesions
#6
Zdeněk Daněk, Jan Gajdziok, Petr Doležel, Hana Landová, David Vetchý, Jan Štembírek
BACKGROUND: Buccal flexible films in the form of solid, thin, mucoadhesive patches can be used as dressings separating aphthous lesions from the environment of the oral cavity, which can in turn shorten the treatment period and reduce the pain perception. METHODS: The clinical study was performed on 36 volunteers suffering from aphthous lesions. The first group was treated using standard means - by application of an oral gel containing cholin salicylas (Mundisal) on the aphthous lesion...
February 15, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28198307/no-pjs-in-the-day-room
#7
Sue Young
In response to your story about Nottingham University Hospitals NHS Trust's campaign to get inpatients out of pyjamas to help speed up recovery (news, 8 February), I trained as a nurse in the late 1980s and getting people dressed was a fundamental part of our training.
February 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28198150/the-effectiveness-of-negative-pressure-therapy-on-infected-wounds-preliminary-results
#8
Federico Lo Torto, Marco Ruggiero, Paola Parisi, Zachary Borab, Manuel Sergi, Bruno Carlesimo
Vacuum-assisted closure (VAC) therapy is a sophisticated system that maintains a closed, humid, sterile and isolated environment. Wound infection is considered a relative contraindication. The objective of this study is to extend the indications for VAC therapy to include infected wounds by demonstrating its ability to increase the antibiotic concentration in the damaged and infected tissues. Patients who presented with ulcers infected with daptomycin-sensitive bacteria were eligible to be enrolled in this prospective study...
February 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28198006/associations-of-early-developmental-milestones-with-adult-intelligence
#9
Trine Flensborg-Madsen, Erik L Mortensen
The study investigated whether age at attainment of 20 developmental milestones within the areas of language, walking, eating, dressing, social interaction, and toilet training was associated with adult intelligence. Mothers of 821 children of the Copenhagen Perinatal Cohort recorded 20 developmental milestones at a 3-year examination, and all children were administered the Wechsler Adult Intelligence Scale when they were 20-34 years old. Later attainment of a number of milestones was associated with lower adult IQ with the strongest associations found for those related to language and social interaction...
February 15, 2017: Child Development
https://www.readbyqxmd.com/read/28196742/comparison-of-different-skin-preservation-methods-with-gamma-irradiation
#10
Linda Guerrero, Bernardo Camacho
Allografts are in constant demand, not only for burn victims, but also for all open wounds as "biological dressings". Tissue quality and security are two of the major concerns of Tissue Banks. There are limited studies published. There has been extensive discussion on the subject of preservation methods for cadaver skin. Most literature available comes from clinical reports. In this research, the authors compared 85% glycerolized non irradiated skin allografts with three glycerolized irradiated skin allografts (using different glycerol concentrations 50%, 70% and 85%)...
February 11, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28196382/bromelain-loading-and-release-from-a-hydrogel-formulated-using-alginate-and-arabic-gum
#11
Janaína Artem Ataide, Letícia Caramori Cefali, Marcia de Araujo Rebelo, Lívia Genovez Spir, Elias Basile Tambourgi, Angela Faustino Jozala, Marco Vinícius Chaud, Edgar Silveira, Xiaochen Gu, Priscila Gava Mazzola
An ideal wound dressing ensures a moist environment around the wound area and absorbs exudates from the wound surface. Topical application of bromelain to incised wounds has been shown to reprogram the wound microenvironment to promote effective tissue repair. Combining the characteristics of hydrogels and bromelain is therefore of great interest. Herein, we describe the development of a hydrogel, formulated using alginate and Arabic gum, for bromelain loading and release. The hydrogel formulation was evaluated using response surface methodology, considering the pH value and the concentration of alginate and Arabic gum...
February 14, 2017: Planta Medica
https://www.readbyqxmd.com/read/28195889/a-biodegradable-hemostatic-gelatin-polycaprolactone-composite-for-surgical-hemostasis
#12
Niann-Tzyy Dai, Keng-Yen Fu, Pai-Shan Hsieh, Yu-Min Hung, Yun-Lung Fang, Nien-Chi Huang, Tzu-Wei Lu, Lien-Guo Dai, Shyi-Gen Chen, Tim-Mo Chen
Massive bleeding is the leading cause of battlefield-related deaths and the second leading cause of deaths in civilian trauma centers. One of the challenges of managing severe wounds is the need to promote hemostasis as quickly as possible, which can be achieved by using hemostatic dressings. In this study, we fabricated 2 kinds of gelatin/polycaprolactone composites with 2 ratios of gelatin/polycaprolactone, 1:1 and 2:1 (GP11 and GP21, respectively). Scanning electron microscopy revealed that the GP11 composite exhibited rougher and more porous structure than the GP21 composite did...
February 14, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28195000/prevention-of-tracheostomy-related-hospital-acquired-pressure-ulcers
#13
Thomas R O'Toole, Natalie Jacobs, Brian Hondorp, Laura Crawford, Lisa R Boudreau, Jill Jeffe, Brian Stein, Phillip LoSavio
Objective To determine if standardization of perioperative tracheostomy care procedures decreased the incidence of hospital-acquired tracheostomy-related pressure ulcers. Methods All patients at least 18 years old who underwent placement of a tracheostomy tube in the operating room from July 1, 2014, through June 30, 2015, were cared for postoperatively through an institutionally adopted quality improvement protocol. This included 4 elements: (1) placement of a hydrocolloid dressing underneath the tracheostomy flange in the postoperative period, (2) removal of plate sutures within 7 days of the tracheostomy procedure, (3) placement of a polyurethane foam dressing after suture removal, and (4) neutral positioning of the head...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28194815/peristomal-psoriasis
#14
C Marshall, S Woodmansey, C C Lyon
BACKGROUND: Psoriasis is a common skin condition, affecting 1.3-2.2% of the population. The prevalence of psoriasis has previously been reported as 11.2% in patients with Crohn disease (CD) and 5.7% in patients with ulcerative colitis. AIM: To assess the prevalence of psoriasis around stoma sites and identify the most effective treatment. METHODS: A departmental database of all patients attendings stoma clinic was accessed between 1 May 2003 and 15 October 2015...
February 13, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28191311/supplemental-smartamine-m-in-higher-energy-diets-during-the-prepartal-period-improves-hepatic-biomarkers-of-health-and-oxidative-status-in-holstein-cows
#15
Mario Vailati-Riboni, Johan S Osorio, Erminio Trevisi, Daniel Luchini, Juan J Loor
BACKGROUND: Feeding higher-energy prepartum is a common practice in the dairy industry. However, recent data underscore how it could reduce performance, deepen negative energy balance, and augment inflammation and oxidative stress in fresh cows. We tested the effectiveness of rumen-protected methionine in preventing the negative effect of feeding a higher-energy prepartum. Multiparous Holstein cows were fed a control lower-energy diet (CON, 1.24 Mcal/kg DM; high-straw) during the whole dry period (~50 d), or were switched to a higher-energy (OVE, 1...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28185377/feeding-corn-distillers-grains-as-an-energy-source-to-gestating-and-lactating-beef-heifers-impact-of-excess-protein-on-feedlot-performance-glucose-tolerance-carcass-characteristics-and-longissimus-muscle-fatty-acid-profile-of-steer-progeny
#16
Patrick J Gunn, Glen A Bridges, Ronald P Lemenager, Jon P Schoonmaker
This study was conducted to determine the impact of dried distiller's grain with solubles (DDGS) from 192 days of gestation through 118 days of lactation on feedlot performance, carcass characteristics, Longissimus muscle (LM) fatty acids and glucose tolerance of male progeny (n = 36). Angus-Simmental heifer dams were fed diets that contained either DDGS (DG) or not (CON) formulated to provide similar daily net energy for gain but differing crude protein. In the feedlot, male progeny were fed a diet devoid of DDGS...
February 9, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28183632/a-potential-bioactive-wound-dressing-based-on-carboxymethyl-cellulose-zno-impregnated-mcm-41-nanocomposite-hydrogel
#17
Rasul Rakhshaei, Hassan Namazi
Lack of antibacterial activity, deficient water vapor and oxygen permeability, and insufficient mechanical properties are disadvantages of existing wound dressings. Hydrogels could absorb wound exudates due to their strong swelling ratio and give a cooling sensation and a wet environment. To overcome these shortcomings, flexible nanocomposite hydrogel films was prepared through combination of zinc oxide impregnated mesoporous silica (ZnO-MCM-41) as a nano drug carrier with carboxymethyl cellulose (CMC) hydrogel...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183599/electrospun-curcumin-loaded-cellulose-acetate-polyvinylpyrrolidone-fibrous-materials-with-complex-architecture-and-antibacterial-activity
#18
Petya B Tsekova, Mariya G Spasova, Nevena E Manolova, Nadya D Markova, Iliya B Rashkov
Novel fibrous materials from cellulose acetate (CA) and polyvinylpyrrolidone (PVP) containing curcumin (Curc) with original design were prepared by one-pot electrospinning or dual spinneret electrospinning. The electrospun materials were characterized by scanning electron microscopy (SEM), fluorescence microscopy, Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy (UV-Vis), differential scanning calorimetry (DSC), water contact angle measurements, and microbiological tests. It was found that the incorporation of Curc into the CA and PVP solutions resulted in an increase of the solution viscosity and obtaining fibers with larger diameters (ca...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183589/terbinafine-loaded-wound-dressing-for-chronic-superficial-fungal-infections
#19
Farnoush Asghari Paskiabi, Shahin Bonakdar, Mohammad Ali Shokrgozar, Mohammad Imani, Zahra Jahanshiri, Masoomeh Shams-Ghahfarokhi, Mehdi Razzaghi-Abyaneh
In spite of developing new drugs and modern formulations, the treatments of chronic fungal infections are still challenging. Fibrous wound dressings are new suggestions for the treatment of chronic superficial infections. In the present study, we formulated an antifungal agent, terbinafine hydrochloride (TFH), which is a hydrophobic drug, in wound dressings prepared by electrospun polycaprolactone, polycaprolactone/gelatin (50:50 w/w) and gelatin. To obtain more water-stable meshes, the preparations were treated by glutaraldehyde and their properties were determined before and after treatment...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183274/disability-in-long-term-care-residents-explained-by-prevalent-geriatric-syndromes-not-long-term-care-home-characteristics-a-cross-sectional-study
#20
Natasha E Lane, Walter P Wodchis, Cynthia M Boyd, Thérèse A Stukel
BACKGROUND: Self-care disability is dependence on others to conduct activities of daily living, such as bathing, eating and dressing. Among long-term care residents, self-care disability lowers quality of life and increases health care costs. Understanding the correlates of self-care disability in this population is critical to guide clinical care and ongoing research in Geriatrics. This study examines which resident geriatric syndromes and chronic conditions are associated with residents' self-care disability and whether these relationships vary across strata of age, sex and cognitive status...
February 10, 2017: BMC Geriatrics
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