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Lumbar spinal stenosis

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https://www.readbyqxmd.com/read/28635357/hypertrophy-of-the-ligamentum-flavum-and-expression-of-transforming-growth-factor-beta
#1
Aierken Amudong, Aikeremujiang Muheremu, Tuerhongjiang Abudourexiti
Objective To explore the relationship between cellular apoptosis and hypertrophy of the ligamentum flavum in the lumbar region. Methods Thirty patients with lumbar spinal stenosis were evaluated. Hypertrophy of the ligamentum flavum was present in 15 patients and absent in 15. Hematoxylin-eosin staining and transforming growth factor beta (TGF-β) immunohistochemical testing were applied to compare these two groups. Results Derangement of fibrous alignment, fibrocartilage changes, and infiltration of inflammatory cells were observed in the patients with hypertrophy of the ligamentum flavum, while fibrous alignment was normal and few inflammatory cells were observed in patients without hypertrophy...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28634709/incidental-durotomy-in-decompression-for-lumbar-spinal-stenosis-incidence-risk-factors-and-effect-on-outcomes-in-the-spine-tango-registry
#2
Christian Herren, Rolf Sobottke, Anne F Mannion, Thomas Zweig, Everard Munting, Philippe Otten, Tim Pigott, Jan Siewe, Emin Aghayev
PURPOSE: The three aims of this Spine Tango registry study of patients undergoing decompression for spinal stenosis were to: report the rate of dural tear (DT) stratified by treatment centre; find factors associated with an increased likelihood of incurring a DT; and compare treatment outcomes in relation to DT (none vs. repaired vs. unrepaired DT). METHODS: Multivariate logistic regression was used to assess the association between DT and patient and treatment characteristics...
June 20, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28634513/correlation-of-lumbar-lateral-recess-stenosis-in-magnetic-resonance-imaging-and-clinical-symptoms
#3
Annina Splettstößer, M Fawad Khan, Bernd Zimmermann, Thomas J Vogl, Hanns Ackermann, Marcus Middendorp, Adel Maataoui
AIM: To assess the correlation of lateral recess stenosis (LRS) of lumbar segments L4/5 and L5/S1 and the Oswestry Disability Index (ODI). METHODS: Nine hundred and twenty-seven patients with history of low back pain were included in this uncontrolled study. On magnetic resonance images (MRI) the lateral recesses (LR) at lumbar levels L4/5 and L5/S1 were evaluated and each nerve root was classified into a 4-point grading scale (Grade 0-3) as normal, not deviated, deviated or compressed...
May 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28632546/clinical-outcome-and-postoperative-ct-measurements-of-microendoscopic-decompression-for-lumbar-spinal-stenosis
#4
Xu Zhou, Lei Zhang, Hai-Long Zhang, Shi-Sheng He, Xin Gu, Guang-Fei Gu, Qing-Song Fu
STUDY DESIGN: This was a retrospective case series. OBJECTIVE: To retrospectively evaluate the clinical outcome of microendoscopic decompression for lumbar spinal stenosis (LSS) including an evaluation of the extent of decompression using computed tomography. SUMMARY OF BACKGROUND DATA: Microendoscopic decompression has been a widely applied procedure to treat LSS with satisfactory outcomes and comparatively fewer complications and revision...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28629944/what-are-the-risk-factors-for-dislocation-in-primary-total-hip-arthroplasty-a-multicenter-case-control-study-of-128-unstable-and-438-stable-hips
#5
M H Fessy, S Putman, A Viste, R Isida, N Ramdane, A Ferreira, A Leglise, B Rubens-Duval, N Bonin, F Bonnomet, A Combes, S Boisgard, D Mainard, S Leclercq, H Migaud
INTRODUCTION: Dislocation after total hip arthroplasty (THA) is a leading reason for surgical revision. The risk factors for dislocation are controversial, particularly those related to the patient and to the surgical procedure itself. The differences in opinion on the impact of these factors stem from the fact they are often evaluated using retrospective studies or in limited patient populations. This led us to carry out a prospective case-control study on a large population to determine: 1) the risk factors for dislocation after THA, 2) the features of these dislocations, and 3) the contribution of patient-related factors and surgery-related factors...
June 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28623897/altered-somatosensory-profile-according-to-quantitative-sensory-testing-in-patients-with-degenerative-lumbar-spine-disorders-scheduled-for-surgery
#6
Yvonne Lindbäck, Hans Tropp, Paul Enthoven, Björn Gerdle, Allan Abbott, Birgitta Öberg
BACKGROUND: Somatosensory profiling in affected and non-affected body regions can strengthen our insight regarding the underlying pain mechanisms, which can be valuable in treatment decision making and to improve outcomes, in patients with degenerative lumbar spine disorders pre-surgery. The aim was to describe somatosensory profiles in patients with degenerative lumbar spine disorders, to identify the proportion with altered somatosensory profile, and to analyze demographic characteristics, self-reported function, pain, and health pre- and 3 months post-surgery...
June 17, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28622909/biomechanical-evaluation-of-a-novel-pedicle-screw-based-interspinous-spacer-a-finite-element-analysis
#7
Hsin-Chang Chen, Jia-Lin Wu, Shou-Chieh Huang, Zheng-Cheng Zhong, Shiu-Ling Chiu, Yu-Shu Lai, Cheng-Kung Cheng
Interspinous spacers have been designed to provide a minimally invasive surgical technique for patients with lumbar spinal stenosis or foraminal stenosis. A novel pedicle screw-based interspinous spacer has been developed in this study, and the aim of this finite element experiment was to investigate the biomechanical differences between the pedicle screw-based interspinous spacer (M-rod system) and the typical interspinous spacer (Coflex-F™). A validated finite element model of an intact lumbar spine was used to analyze the insertions of the Coflex-F™, titanium alloy M-rod (M-Ti), and polyetheretherketone M-rod (M-PEEK), independently...
June 13, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28614284/cervical-spine-deformities-in-children-with-rhizomelic-chondrodysplasia-punctata
#8
Oussama Abousamra, Vinay Kandula, Angela L Duker, Kenneth J Rogers, Michael B Bober, William G Mackenzie
BACKGROUND: Cervical spine deformity in rhizomelic chondrodysplasia punctata (RCDP) has been described with different findings reported in the literature. However, available literature provides limited data from a few cases with magnetic resonance imaging (MRI) of the cervical spine. Our report describes the MRI findings in a group of children with RCDP, aiming to reach a better understanding of this pathology. METHODS: An Institutional Review Board-approved RCDP Registry was created at our institution with the goal of identifying pertinent medical issues over the lifespan of individuals with RCDP...
June 13, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28614282/clinical-outcomes-of-cervical-spinal-surgery-for-cervical-myelopathic-patients-with-coexisting-lumbar-spinal-canal-stenosis-tandem-spinal-stenosis-a-retrospective-analysis-of-297-cases
#9
Tsuyoshi Yamada, Toshitaka Yoshii, Naoki Yamamoto, Takashi Hirai, Hiroyuki Inose, Tsuyoshi Kato, Shigenori Kawabata, Atsushi Okawa
STUDY DESIGN: Retrospective observational study. OBJECTIVE: We evaluated the prevalence and clinical characteristics of tandem spinal stenosis (TSS) in patients with cervical myelopathy including ossification of the posterior longitudinal ligament of the cervical spine (C-OPLL). SUMMARY OF BACKGROUND DATA: Concurrent cervical and lumbar spinal canal stenosis is generally reported as TSS. Most previous studies have used magnetic resonance imaging to evaluate spinal stenosis in the cervical and lumbar spine...
June 13, 2017: Spine
https://www.readbyqxmd.com/read/28609751/aneurysmal-subarachnoid-hemorrhage-lead-to-systemic-upregulation-of-il-23-il-17-inflammatory-axis
#10
Shafqat Rasul Chaudhry, Erdem Güresir, Hartmut Vatter, Thomas M Kinfe, Dirk Dietrich, Alf Lamprecht, Sajjad Muhammad
IL-23 and IL-17 are pro-inflammatory cytokines. IL-23 is secreted by activated macrophages and dendritic cells, while IL-17 by Th17 cells. Serum IL-23 and IL-17 are known to be elevated in numerous inflammatory diseases including neurodegenerative diseases. The role of serum IL-23 and IL-17 in aneurysmal subarachnoid hemorrhage (aSAH) has still not been investigated. The present work investigates the serum IL-23 and IL-17 levels and their association with post hemorrhagic complications and clinical outcome in patients with aSAH...
June 10, 2017: Cytokine
https://www.readbyqxmd.com/read/28604494/risk-factors-for-and-complications-after-surgical-delay-in-elective-single-level-lumbar-fusion
#11
Scott C Wagner, Joseph S Butler, Ian D Kaye, Arjun Sebastian, Patrick B Morrissey, Christopher Kepler
STUDY DESIGN: Retrospective cohort Objective: To assess the incidence of and risk factors for delay of elective lumbar fusion surgery, as well as medical and surgical complications associated with surgical delay. SUMMARY OF BACKGROUND DATA: Lumbar fusion is a well-established treatment for patients with degenerative spondylolisthesis with stenosis who have failed conservative management. Rarely, patients admitted for elective lumbar fusion may experience a delay in surgery past the day of admission...
June 9, 2017: Spine
https://www.readbyqxmd.com/read/28604486/indication-variability-in-degenerative-lumbar-spine-surgery-a-4-nation-survey
#12
Bertrand Debono, Guillaume Lonjon, Luis Alvarez Galovich, Sébastien Kerever, Ben Guiot, Sven-Oliver Eicker, Olivier Hamel, Florian Ringel
STUDY DESIGN: Electronic survey OBJECTIVE.: To identify the international nuances in surgical treatment patterns for severals lumbar degenerative conditions. Specifically, identify 1) Differences in responses in each country group; 2) Identify different treatment trends across countries SUMMARY OF BACKGROUND DATA.: Significant variations in treatment of lumbar degenerative conditions exist among spine surgeons, related to the lack of established consensus in the literature. METHODS: An online survey with preformulated answers was submitted to 52 orthopaedic surgeons, 50 neurosurgeons neurosurgeons from 4 different countries (USA, France, Spain and Germany) regarding 5 vignette-cases...
June 9, 2017: Spine
https://www.readbyqxmd.com/read/28600006/is-there-still-a-role-for-interspinous-spacers-in-the-management-of-neurogenic-claudication
#13
REVIEW
Vijay M Ravindra, Zoher Ghogawala
Lumbar spinal stenosis with neurogenic claudication is prevalent in the elderly population. Decompression for this condition is the operation most commonly used to treat older patients. Because of the risks associated with open decompression procedures, particularly in older patients with comorbidities, minimally invasive procedures with implantation of interspinous process devices have been developed. This article reviews the current role of interspinous spacers in the treatment of lumbar spinal stenosis with neurogenic claudication and discusses the body of literature surrounding this treatment alternative...
July 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28598295/pelvic-retroversion-a-compensatory-mechanism-for-lumbar-stenosis
#14
Sina Pourtaheri, Akshay Sharma, Jason Savage, Iain Kalfas, Thomas E Mroz, Edward Benzel, Michael P Steinmetz
OBJECTIVE The flexed posture of the proximal (L1-3) or distal (L4-S1) lumbar spine increases the diameter of the spinal canal and neuroforamina and can relieve symptoms of neurogenic claudication. Distal lumbar flexion can result in pelvic retroversion; therefore, in cases of flexible sagittal imbalance, pelvic retroversion may be compensatory for lumbar stenosis and not solely compensatory for the sagittal imbalance as previously thought. The authors investigate underlying causes for pelvic retroversion in patients with flexible sagittal imbalance...
June 9, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28597302/the-impact-of-hypertension-on-the-occurrence-of-postoperative-spinal-epidural-hematoma-following-single-level-microscopic-posterior-lumbar-decompression-surgery-in-a-single-institute
#15
Yasushi Fujiwara, Hideki Manabe, Bunichiro Izumi, Takahiro Harada, Kazuyoshi Nakanishi, Nobuhiro Tanaka, Nobuo Adachi
PURPOSE: Postoperative spinal epidural hematoma (PSEH) is one of the most hazardous complications after spine surgery. A recent study has reported that a ≥50 mmHg increase in systolic blood pressure after extubation was a significant risk factor for symptomatic PSEH. In this paper, the impact of hypertension on PSEH occurrence was investigated. METHODS: Among a total of 2468 patients who underwent single level microscopic posterior decompression surgery for lumbar spinal stenosis in a single institute, 15 (0...
June 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28583914/association-between-col11a1-rs1337185-and-adamts5-rs162509-gene-polymorphisms-and-lumbar-spine-pathologies-in-chinese-han-population-an-observational-study
#16
Hua Jiang, Qinghua Yang, Jie Jiang, Xinli Zhan, Zengming Xiao
OBJECTIVES: A previous study identified a significant association between several single nucleotide polymorphisms (SNPs) and lumbar disc degeneration (LDD) in Indians. To validate the association between these SNPs and specific lumbar spine pathologies, we performed a case-control study in Chinese Han population. DESIGN: An observational study. SETTING: University Hospital in Nanning, China. PARTICIPANTS: This study included 428 patients with LDD and 400 normal controls...
June 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28580526/deformable-appearance-pyramids-for-anatomy-representation-landmark-detection-and-pathology-classification
#17
Qiang Zhang, Abhir Bhalerao, Charles Hutchinson
PURPOSE: Representation of anatomy appearance is one of the key problems in medical image analysis. An appearance model represents the anatomies with parametric forms, which are then vectorised for prior learning, segmentation and classification tasks. METHODS: We propose a part-based parametric appearance model we refer to as a deformable appearance pyramid (DAP). The parts are delineated by multi-scale local feature pyramids extracted from an image pyramid. Each anatomy is represented by an appearance pyramid, with the variability within a population approximated by local translations of the multi-scale parts and linear appearance variations in the assembly of the parts...
June 3, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28579287/effect-of-1-or-2-level-posterior-lumbar-interbody-fusion-on-global-sagittal-balance
#18
Jae Hwan Cho, Youn-Suk Joo, Cheongsu Lim, Chang Ju Hwang, Dong-Ho Lee, Choon Sung Lee
BACKGROUND CONTEXT: Sagittal imbalance is associated with poor clinical outcomes in patients with degenerative lumbar disease. However, there is no consensus on the impact of posterior lumbar interbody fusion (PLIF) on local and global sagittal balance. PURPOSE: To reveal the effect of 1- or 2-level PLIF on global sagittal balance. STUDY DESIGN/SETTING: A retrospective case-control study. PATIENTS SAMPLE: This study included 88 patients who underwent a 1- or 2-level PLIF for spinal stenosis with spondylolisthesis...
June 1, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28575297/prognostic-factors-for-satisfaction-after-decompression-surgery-for-lumbar-spinal-stenosis
#19
Rune Tendal Paulsen, Jamal Bech Bouknaitir, Søren Fruensgaard, Leah Carreon, Mikkel Andersen
BACKGROUND: Surgical treatment for lumbar spinal stenosis is associated with both short- and long-term benefits with improvements in patient function and pain. Even though most patients are satisfied postoperatively, some studies report that up to one-third of patients are dissatisfied. OBJECTIVE: To present clinical outcome data and identify prognostic factors related to patient satisfaction 1 yr after posterior decompression surgery for lumbar spinal stenosis...
June 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28567219/the-effect-of-anxiety-depression-and-optimism-on-postoperative-satisfaction-and-clinical-outcomes-in-lumbar-spinal-stenosis-and-degenerative-spondylolisthesis-patients-cohort-study
#20
Jaewon Lee, Hong-Sik Kim, Kyu-Dong Shim, Ye-Soo Park
BACKGROUND: The aim of this study is to evaluate the effect of depression, anxiety, and optimism on postoperative satisfaction and clinical outcomes in patients who underwent less than two-level posterior instrumented fusions for lumbar spinal stenosis and degenerative spondylolisthesis. METHODS: Preoperative psychological status of subjects, such as depression, anxiety, and optimism, was evaluated using the Hospital Anxiety and Depression Scale (HADS) and the Revised Life Orientation Test (LOT-R)...
June 2017: Clinics in Orthopedic Surgery
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