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https://www.readbyqxmd.com/read/28822778/diabetes-care-program-of-nova-scotia-celebrating-25-years-of-improving-diabetes-care-in-nova-scotia
#1
REVIEW
Jennifer I Payne, Margaret J Dunbar, Pamela Talbot, Meng H Tan
The Diabetes Care Program of Nova Scotia (DCPNS)'s mission is "to improve, through leadership and partnerships, the health of Nova Scotians living with, affected by, or at risk of developing diabetes." Working together with local, provincial and national partners, the DCPNS has improved and standardized diabetes care in Nova Scotia over the past 25 years by developing and deploying a resourceful and collaborative program model. This article describes the model and highlights its key achievements. With balanced representation from frontline providers through to senior decision makers in health care, the DCPNS works across the age continuum, supporting the implementation of national clinical practice guidelines and, when necessary, developing provincial guidelines to meet local needs...
August 16, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28812833/evaluating-the-implementation-and-feasibility-of-a-web-based-tool-to-support-timely-identification-and-care-for-the-frail-population-in-primary-healthcare-settings
#2
Beverley Lawson, Tara Sampalli, Stephanie Wood, Grace Warner, Paige Moorhouse, Rick Gibson, Laurie Mallery, Fred Burge, Lisa G Bedford
BACKGROUND: Understanding and addressing the needs of frail persons is an emerging health priority for Nova Scotia and internationally. Primary healthcare (PHC) providers regularly encounter frail persons in their daily clinical work. However, routine identification and measurement of frailty is not standard practice and, in general, there is a lack of awareness about how to identify and respond to frailty. A web-based tool called the Frailty Portal was developed to aid in identifying, screening, and providing care for frail patients in PHC settings...
March 7, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28811876/individual-quality-and-age-but-not-environmental-or-social-conditions-modulate-costs-of-reproduction-in-a-capital-breeder
#3
Lucie Debeffe, Jocelyn Poissant, Philip D McLoughlin
Costs associated with reproduction are widely known to play a role in the evolution of reproductive tactics with consequences to population and eco-evolutionary dynamics. Evaluating these costs as they pertain to species in the wild remains an important goal of evolutionary ecology. Individual heterogeneity, including differences in individual quality (i.e., among-individual differences in traits associated with survival and reproduction) or state, and variation in environmental and social conditions can modulate the costs of reproduction; however, few studies have considered effects of these factors simultaneously...
August 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28803396/early-regression-of-carotid-intima-media-thickness-after-bariatric-surgery-and-its-relation-to-serum-leptin-reduction
#4
G Lambert, Marcelo Miranda de Oliveira Lima, A C Felici, J C Pareja, A C J Vasques, F S Novaes, S Rodovalho, F F P Hirsch, J R Matos-Souza, Élinton A Chaim, B Geloneze
PURPOSE: Bariatric surgery (BS) promotes carotid intima-media thickness (C-IMT) regression as early as 6 months post-surgery. To verify whether C-IMT regression occurs even earlier, we aimed at the effect of Roux-en-Y gastric bypass (RYGBP) and biliopancreatic diversion (BPD) on C-IMT 1-2 months and 12 months post-surgery. SUBJECTS/METHODS: Prospective trial. BS was performed on 109 patients either with (RYGBP = 42; BDP = 40) or without type 2 diabetes (RYGBP = 27)...
August 12, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28799783/gluten-free-foods-in-rural-maritime-provinces-limited-availability-high-price-and-low-iron-content
#5
Jennifer A Jamieson, Laura Gougeon
We investigated the price difference between gluten-free (GF) and gluten-containing (GC) foods available in rural Maritime stores. GF foods and comparable GC items were sampled through random visits to 21 grocery stores in nonurban areas of Nova Scotia, New Brunswick, and Prince Edward Island, Canada. Wilcoxon rank tests were conducted on price per 100 g of product, and on the price relative to iron content; 2226 GF foods (27.2% staple items, defined as breads, cereals, flours, and pastas) and 1625 GC foods were sampled, with an average ± SD of 66 ± 2...
August 11, 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28796829/new-data-on-weddell-seal-leptonychotes-weddellii-colonies-a-genetic-analysis-of-a-top-predator-from-the-ross-sea-antarctica
#6
Ighor Antunes Zappes, Anna Fabiani, Valerio Sbordoni, Arnold Rakaj, Roberto Palozzi, Giuliana Allegrucci
In this paper, we studied the genetic variability in Weddell seal from colonies in Terra Nova Bay and Wood Bay, both sites located in the Ross Sea area, Antarctica. Two mitochondrial genes and one nuclear gene, with different mutation rates, were sequenced to investigate the haplotype diversity of the colonies and to test for a possible recent expansion. Fifteen microsatellites were used to analyze their genetic structure. Sequenced genes and microsatellites were also used to estimate the effective population size of the studied colonies and the Ross Sea seal population...
2017: PloS One
https://www.readbyqxmd.com/read/28794620/spreading-improvements-for-advanced-copd-care-through-a-canadian-collaborative
#7
Graeme M Rocker, Claudia Amar, Wendy L Laframboise, Jane Burns, Jennifer Y Verma
BACKGROUND: A year-long pan-Canadian quality improvement collaborative (QIC) led by the Canadian Foundation for Healthcare Improvement (CFHI) supported the spread of the successful Halifax, Nova Scotia-based INSPIRED COPD Outreach Program™ to 19 teams in the 10 Canadian provinces. We describe QIC results, addressing two main questions: 1) Can the results of the Nova Scotia INSPIRED model be replicated elsewhere in Canada? 2) How did the teams implement and evaluate their versions of the INSPIRED program? METHODS: Collaborative faculty selected measures that were evidence-based, relatively simple to collect, and relevant to local context...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28793996/ultra-processed-foods-in-human-health-a-critical-appraisal
#8
Michael J Gibney, Ciarán G Forde, Deirdre Mullally, Eileen R Gibney
The NOVA classification of foods proposes 4 categories: unprocessed or minimally processed foods, processed culinary ingredients, processed foods, and ultra-processed foods and drinks (UPFDs). It is argued that the latter relies heavily on modifications to foods, resulting in enhanced amounts of salt, added sugar, and fat as well as the use of additives in an attempt to make this food category highly palatable. It further argues that controlling food processing, rather than examining nutrients, should be foremost in shaping nutrition policy...
August 9, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28793081/methodological-aspects-of-dietary-quality-assessment-in-brazil-systematic-review
#9
Dayane de Castro Morais, Luís Fernando de Sousa Moraes, Danielle Cristina Guimarães da Silva, Carina Aparecida Pinto, Juliana Farias de Novaes
This systematic review analyzes the methodologies of Brazilian studies that have used indices to evaluate dietary quality. A systematic search was performed of electronic databases (Lilacs, Medline, SciELO and Scopus) with no restriction on the year of publication of the studies. Original, Brazilian articles were selected that assessed dietary quality using the Healthy Eating Index (HEI) or its revised versions. The descriptors were as follows: dietary quality; healthy eating index; and dietary quality index...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28783850/fetal-skeletal-lethal-dysplasia-case-report
#10
Alexandre Mello Savoldi, Maria Auxiliadora Monteiro Villar, Heloisa Novaes Machado, Juan C Llerena Júnior
The clinical management and decision-making in pregnancies in which there is suspicion of lethal fetal malformations during the prenatal period, such as lethal skeletal dysplasia (SD), demand a multidisciplinary approach coordinated by an experienced physician. Based on the presentation of a case of osteogenesis imperfecta type IIA, we offer and discuss recommendations with the intention of organizing clinical and laboratory investigations aiming toward the clinical management, prognosis, and etiological diagnosis of these malformations, as well as genetic counselling to patients who wish to become pregnant...
August 7, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28782809/overview-of-infectious-salmon-anaemia-virus-isav-in-atlantic-canada-and-first-report-of-an-isav-north-american-hpr0-subtype
#11
N Gagné, F LeBlanc
The infectious salmon anaemia virus (ISAV) is an important viral disease of farmed Atlantic salmon that has caused considerable financial losses for salmon farmers around the world, including Atlantic Canada. It is listed as a notifiable disease by the World Organization for Animal Health, and to this day, culling of infected cages or farms remains the current practice in many countries to mitigate the spread of the virus. In Atlantic Canada, ISAV was first detected in 1996 and continues to be detected. While some outbreaks seemed to have arisen from isolated infections of unknown source, others were local clusters resulting from horizontal spread of infection...
August 7, 2017: Journal of Fish Diseases
https://www.readbyqxmd.com/read/28780218/predicting-the-risk-of-macrosomia-at-mid-pregnancy-among-non-diabetics-a%C3%A2-retrospective-cohort-study
#12
Elizabeth Jeffers, Linda Dodds, Victoria Allen, Christy Woolcott
OBJECTIVE: To identify factors known in mid-pregnancy to be associated with risk of macrosomia (≥4000 g) among non-diabetic women and to develop a risk score to allow early identification of women at high risk. METHODS: Data were obtained from a population-based perinatal database and a hospital laboratory database in Nova Scotia, Canada. The study included singleton live births born to non-diabetic women between 1998 and 2005. Logistic regression was used to identify risk factors significantly associated with macrosomia...
August 2, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28774778/frontiers-in-endocrine-disruption-impacts-of-organotin-on-the-hypothalamus-pituitary-thyroid-axis
#13
REVIEW
Ana Paula Santos-Silva, Marcelle Novaes Andrade, Paula Pereira-Rodrigues, Francisca Diana Paiva-Melo, Paula Soares, Jones Bernardes Graceli, Glaecir Roseni Mundstock Dias, Andrea Claudia Freitas Ferreira, Denise Pires de Carvalho, Leandro Miranda-Alves
Endocrine disruptors (EDs), chemical substances widely used in industry and ubiquitously distributed in the environment, are able to interfere with the synthesis, release, transport, metabolism, receptor binding, action, or elimination of endogenous hormones. EDs affect homeostasis mainly by acting on nuclear and nonnuclear steroid receptors but also on serotonin, dopamine, norepinephrine and orphan receptors in addition to thyroid hormone receptors. Tributyltin (TBT), an ED widely used as a pesticide and biocide in antifouling paints, has well-documented actions that include inhibiting aromatase and affecting the nuclear receptors PPARγ and RXR...
July 31, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28774350/correlation-of-age-and-rurality-with-low-urgency-use-of-emergency-medical-services-luems-a-geographic-analysis
#14
Mikiko Terashima, Alix J E Carter
OBJECTIVES: Studies suggest that addressing the needs of the older population in rural areas may substantially reduce their low-urgency use of emergency medical services (LUEMS). It may ultimately also help improve the efficiency in our health system. There is, however, a dearth of evidence substantiating geographic patterns in LUEMS by different age cohorts. This exploratory study was aimed to clarify the understanding of emergency medical services (EMS) use in Nova Scotia through a geographic analysis...
August 4, 2017: CJEM
https://www.readbyqxmd.com/read/28770702/prevalence-of-anti-dfs70-antibodies-in-patients-with-and-without-systemic-autoimmune-rheumatic-diseases
#15
Ora Shovman, Boris Gilburd, Chen Chayat, Howard Amital, Pnina Langevitz, Abdulla Watad, Adi Guy, Dolores Perez, Danielle Azoulay, Miri Blank, Yael Segal, Chelsea Bentow, Michael Mahler, Yehuda Shoenfeld
OBJECTIVES: Autoantibodies to the dense fine speckled 70 (DFS70) antigen are common among antinuclear antibodies (ANA) positive healthy individuals (HI). We assessed the prevalence of anti-DFS70 antibodies in patients with and without ANA-associated rheumatic diseases (AARDs) by two methods: chemiluminescent immunoassay (CIA) and an indirect immunofluorescence (IIF) assay based on immunoadsorption for DFS70. METHODS: Fifty-one ANA-positive sera samples from patients with confirmed clinical diagnosis of AARD, 92 samples from HI and 85 samples submitted to a reference laboratory for routine ANA testing were evaluated for the presence of anti-DFS70 antibodies...
July 27, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28769635/a-new-paraleius-species-acari-oribatida-scheloribatidae-associated-with-bark-beetles-curculionidae-scolytinae-in-canada
#16
Wayne Knee
Bark beetles (Scolytinae) are hosts to a broad diversity of mites (Acari), including several genera of Oribatida (Sarcoptiformes). Of these, Paraleius (Scheloribatidae) species are the most frequently collected oribatid mites associated with bark beetles. A new species was discovered while surveying the acarofauna of bark beetles in Eastern Canada and is described as Paraleius leahaesp. n. (Oribatida, Scheloribatidae). This species was collected from two host beetle species, Hylastes porculus Erickson and Dendroctonus valens LeConte, in Ontario, New Brunswick and Nova Scotia...
2017: ZooKeys
https://www.readbyqxmd.com/read/28768201/human-tfiih-kinase-cdk7-regulates-transcription-associated-chromatin-modifications
#17
Christopher C Ebmeier, Benjamin Erickson, Benjamin L Allen, Mary A Allen, Hyunmin Kim, Nova Fong, Jeremy R Jacobsen, Kaiwei Liang, Ali Shilatifard, Robin D Dowell, William M Old, David L Bentley, Dylan J Taatjes
CDK7 phosphorylates the RNA polymerase II (pol II) C-terminal domain CTD and activates the P-TEFb-associated kinase CDK9, but its regulatory roles remain obscure. Here, using human CDK7 analog-sensitive (CDK7as) cells, we observed reduced capping enzyme recruitment, increased pol II promoter-proximal pausing, and defective termination at gene 3' ends upon CDK7 inhibition. We also noted that CDK7 regulates chromatin modifications downstream of transcription start sites. H3K4me3 spreading was restricted at gene 5' ends and H3K36me3 was displaced toward gene 3' ends in CDK7as cells...
August 1, 2017: Cell Reports
https://www.readbyqxmd.com/read/28767925/autism-spectrum-disorders-an-updated-guide-for-genetic-counseling
#18
Karina Griesi-Oliveira, Andréa Laurato Sertié
Autism spectrum disorder is a complex and genetically heterogeneous disorder, which has hampered the identification of the etiological factors in each patient and, consequently, the genetic counseling for families at risk. However, in the last decades, the remarkable advances in the knowledge of genetic aspects of autism based on genetic and molecular research, as well as the development of new molecular diagnostic tools, have substantially changed this scenario. Nowadays, it is estimated that using the currently available molecular tests, a potential underlying genetic cause can be identified in nearly 25% of cases...
April 2017: Einstein
https://www.readbyqxmd.com/read/28767888/analog-models-of-flanking-structures-and-a-natural-example-in-the-quadril%C3%A3-tero-ferr%C3%A3-fero-minas-gerais
#19
Caroline J S Gomes, Braulio A Rodrigues, Issamu Endo
The aim of this study is to present analog models of flanking structures and to analyze the Fábrica Nova synform, Quadrilátero Ferrífero, Minas Gerais, from a geometric point of view. We set up seven models using a linear viscous silicone and produced flanking structures with a shear velocity of 2 cm h-1. At different initial orientations with respect to the shear zone boundary, a rigid cross-cutting element with lubricated boundaries was deformed via sinistral bulk flow at a shear strain of γ = 1.28. The most interesting features of our experiments are the geometries of the different marker lines, which are heterogeneous and resulted from thickening and thinning of the silicone at the cross-cutting element terminations...
July 31, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28764133/distribution-of-cd-pb-and-cu-between-dissolved-fraction-inorganic-particulate-and-phytoplankton-in-seawater-of-terra-nova-bay-ross-sea-antarctica-during-austral-summer-2011-12
#20
S Illuminati, A Annibaldi, T Romagnoli, G Libani, M Antonucci, G Scarponi, C Totti, C Truzzi
During the austral summer 2011-2012, the metal quotas of Cd, Pb and Cu in the phytoplankton of Terra Nova Bay (TNB, Antarctica) were measured for the first time. Evolution of all the three metal distributions between dissolved and particulate fractions during the season was also evaluated. Metal concentrations were mainly affected by the dynamic of the pack ice melting and phytoplankton activity. In mid-December when TNB area was covered by a thick pack ice layer and phytoplankton activity was very low, all the three metals were present mainly in their dissolved species...
October 2017: Chemosphere
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