Nattachai Srisawat, Kearkiat Praditpornsilpa, Kanitha Patarakul, Malee Techapornrung, Tinnapop Daraswang, Theerapon Sukmark, Kamol Khositrangsikun, Apinya Fakthongyoo, Petchdee Oranrigsupak, Laksamon Praderm, Ummarit Suwattanasilpa, Sadudee Peerapornratana, Passisd Loahaveeravat, Nattachai Suwachittanont, Thaksa-on Wirotwan, Chayanat Phonork, Sarinya Kumpunya, Khajohn Tiranathanagul, Chintana Chirathaworn, Somchai Eiam-ong, Kriang Tungsanga, Visith Sitprija, John A Kellum, Natavudh Townamchai
AKI is one of the most serious complications of leptospirosis, an important zoonosis in the tropics. Recently, NGAL, one of the novel AKI biomarkers, is extensively studied in various specific settings such as sepsis, cardiac surgery, and radiocontrast nephropathy. In this multicenter study, we aimed to study the role of NGAL as an early marker and an outcome predictor of leptospirosis associated AKI. Patients who presented with clinical suspiciousness of leptospirosis were prospectively enrolled in 9 centers from August 2012 to November 2014...
2015: PloS One