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Sylvain Carras, Françoise Berger, Lara Chalabreysse, Evelyne Callet-Bauchut, Jean-François Cordier, Gilles Salles, Nicolas Girard
Primary cardiac lymphoma (PCL) represents a rare subset of extranodal lymphomas for which the primary lesion arises from the heart and/or the pericardium. Fundamental characteristics of PCL remain uncertain, regarding optimal diagnosis strategy, pathological features, treatments, as well as prognostic factors. This is a single-institution retrospective study of patients with histologically proven lymphoma, presenting with exclusive or predominant myocardial invasion at time of diagnosis. Thirteen patients were included, all of whom had symptoms related to cardiac tumour location with chronic chest pain in six (46%), dyspnea in seven (54%) and arythmia in three (23%)...
December 2017: Hematological Oncology
F Aboukhoudir, I Aboukhoudir, O Rica, E Benamo, F Latil Plat, V Ciobotaru, S Rekik
Pheochromocytoma is a rare tumor potentially life-threatening and associated with non specific and diverse symptomatology. Cardiac symptoms may mislead diagnosis; they could manifest as myocardial sideration concomitant to a hypertensive peak or supraventricular arythmia. We report a case of pheochromocytoma associated with hypokaliemia revealed by a myocardial ischemia with acute cardiac failure and severe left ventricular depression and complete reversal after surgery.
November 2015: Annales de Cardiologie et D'angéiologie
Robert G Salomon, Wenzhao Bi
SIGNIFICANCE: A diverse family of lipid-derived levulinaldehydes, isolevuglandins (isoLGs), is produced by rearrangement of endoperoxide intermediates generated through both cyclooxygenase (COX) and free radical-induced cyclooxygenation of polyunsaturated fatty acids and their phospholipid esters. The formation and reactions of isoLGs with other biomolecules has been linked to alcoholic liver disease, Alzheimer's disease, age-related macular degeneration, atherosclerosis, cardiac arythmias, cancer, end-stage renal disease, glaucoma, inflammation of allergies and infection, mitochondrial dysfunction, multiple sclerosis, and thrombosis...
June 20, 2015: Antioxidants & Redox Signaling
Agnieszka Kolak, Elzbieta Starosławska, Tomasz Kubiatowski, Dariusz Kieszko, Paweł Cisek, Krzysztof Ireneusz Patyra, Dariusz Surdyka, Agnieszka Mocarska, Franciszek Burdan
Modern cancer therapy prolongs patients life but commonly increases incidence of treatment-related complications. One of such adverse effect is a neurotoxicity, which usually manifestates as peripheral neuropathies (CIPN), characterised by various sensory (tingling, numbness, pain), motor (foot and hands drop, fastening buttons difficulties) and autonomic (constipation, arythmia) abnormalities as well as pain. Despite of intensive epidemiological and clinical studies, standardized diagnostic criteria and methods of the neuropathy prevention and treatment have not been fully established...
November 2013: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Laure De Decker, Marine Gegu, Pascal Chevalet, Gilles Berrut
UNLABELLED: The atrial fibrillation (AF) is one of the most important cause of arythmia and cerebrovascular disease in clinical practice. Comorbidity is defined as the association of active chronical diseases and a target disease. METHOD: comparison between burden illness of the patients in interventional (n=4) and observational studies, form Medline database (n=4), was performed. RESULTS: the level of comorbidity tend to be higher in patients from interventional than large observational studies...
December 2013: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
H Burgan, H Burri
Endurance sports can predispose to the occurrence of certain arrhythmias, making them more frequent in athletes than in the general population. Endurance athletes often exhibit electrocardiographic modifications that are difficult to interpret without specific knowledge of the athlete's ECG. Some of these ECG modifications and arrhythmias are benign, however others can be potentially life threatening.
March 6, 2013: Revue Médicale Suisse
I Philip, I Leblanc, C Berroëta, S Mouren, V Chterev, P Bourel
Atrial fibrillation (AF) is the most frequent arythmia. During the perioperative period and in intensive care units, management of patients with AF is frequent and difficult. As in cardiology, two main issues are present: the risk of acute hemodynamically instability and the risk of thromboembolic complication. Cardiological guidelines recently published must guide the management of patients in this context. Two main factors must be kept in mind: acute AF in these situations are often of short duration; the risk of anticoagulation can be superior to the risk of thrombotic complication in this situation...
November 2012: Annales Françaises D'anesthèsie et de Rèanimation
A P Ryzhak, B I Kuznik, V N Putkovskaia, G A Ryzhak
The study of peptide geroprotector's biological activity was conducted on basis of calf aorta extract Slavinorm in experimental models of hiperlypidemia and acute myocardial infarction. The study results show that Slavinorm possesses the evident antiatherogenic effect. It appears in blood lipid spectrum parameters optimization, including atherogenic coefficient normalization at the expense of high density lipids level increase and other cholesterol fractions decrease. Slavinorm manifested antiischemic effects in the model of acute myocardial infarction, which was expressed in significant decrease of necrotic zone after 4-hours coronary artery occlusion in comparison with parameters in control animals and in low frequency of postobstructive arythmia...
2012: Advances in Gerontology, Uspekhi Gerontologii
Habiba Mizouni, Younes Arous, Mohamed Hedhli, Maha Mahmoud, Emna Menif
BACKGROUND: Due to the recent technological progress, multislice computerized tomography (MSCT) allows visualizing the heart and coronary arteries. Multislice computed tomography is non invasive and provides high quality images.Its main limits are arythmia, tachycardia and coronary calcifications. But the main drawback with MSCT is the radiation dose. AIM: Report of usefuluess and indications of multislice CT scanner. METHODS: Rzview of literature RESULTS: Although the indications of MSCT did not reach a guideleness level yet, some trends can be stated...
March 2012: La Tunisie Médicale
Lars Møller Pedersen, Morten Petersen, Inger Søndergaard
Flumazenil is a benzodiazepine antagonist. It is widely used as an antidote in comatose patients suspected of having ingested a benzodiazepine overdose. Flumazenil is known to induce cardiac arythmias and seizures, in part because of drug interactions. We present a 75-year-old woman, who was brought to the Emergency Department with a drug overdose following a suicide attempt. She developed generalized seizures shortly after the administration of flumazenil.
June 1, 2009: Ugeskrift for Laeger
D Mioulet, L Braem, P Heno, P Paule, J-M Peloni, D Bonnet, L Fourcade
Primary or secondary cardiac lymphomas are not frequent. Their clinical expression is unusual and the diagnosis is rarely made during the patient's life. Our case report, which is a slow atrial flutter with a pericardial effusion, is an uncommon discovery mode for a malignant lymphoma. Their diagnosis and the mechanism of the arythmia were allowed by non-invasive cardiac imagery (transesophageal echography and magnetic resonance imaging), which showed a tumour-like infiltration of the right atrium, of the right ventricle posterior wall, and of the atrioventricular junction...
April 2009: Annales de Cardiologie et D'angéiologie
V Zamrazil
Subclinical thyroids disease (STD) is recently defined term in clinical thyroidology, which includes mainly functional disorders. Basic diagnostic signs are: normal values of thyroid hormones (fT4, fT3) and elevated TSH level (subclinical hypothyroidism) or suppresed TSH level (subclinical hyperthyroidism). In a category of STD may be included subclinical autoimunne thyroiditis (elevated level of thyroid antigens antibodies and/or hypoechogenity in sonographic screen, increased volume of the thyroid without clinical symptoms and/or autoimminity) and microscopic lesions of papillary thyroid carcinoma...
July 2007: Vnitr̆ní Lékar̆ství
Takako Migita, Ryouji Kawaguchi, Miwako Nakao, Nobuyoshi Sato, Naoki Tahara, Hiroshi Adachi, Shima Taguchi
BACKGROUND: Anticoagulated patients who undergo surgry have been increasing in number. They may develop thrombo-embolic and/or bleeding complications. METHODS: We studied 79 patients retrospectively who had undergone elective surgery from April 2002 through December 2003. We studied their basal diseases, types of anticoagulants, stopping or continuing anticoagulants during their surgical period, thrombo-embolic and/or bleeding complications and changing of the anesthetic method...
February 2006: Masui. the Japanese Journal of Anesthesiology
Ge Shen, San-tai Song, Ze-fei Jiang, Shou-geng Bian, Guang-ru Xie, Ya-jie Wang, Jie-jun Wang
OBJECTIVE: To investigate the effect and safety of zoledronic acid (Zoledex) in patients with cancer-induced hypercalcemia. METHODS: Seventeen patients with cancer-induced hypercalcemia (corrected blood calcium > 2.70 mmol/L) were treated intravenously by 4 mg zoledex within 15 minutes on the first day. The corrected blood calcium was observed every 4 days in the following 28 days. RESULTS: The response rate was 94.1% (16/17). The mean corrected blood calcium became normal after the first dose of zoledex (P < 0...
October 2005: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Alain Delabays, Adam Fischer
This paper answers to the main questions the surgeon is asking before an intervention on a cardiac valve. The optimal timing of surgery, the type of intervention (repair versus replacement), the complementary investigations and the treatment of associated arythmias are discussed. Particular emphasis is put on the best technique to solve these problems.
July 2004: Revue Médicale de la Suisse Romande
M A Delrue, D Lacombe
Ectrodactyly and phocomelia are well known limbs malformations. They can be a part of various syndromes, and are more often transmitted with dominant autosomal Inheritance with variable expression and Incomplete penetrance. Different loci have been Identified for ectrodactyly (SHFM1 at 7q21.3q22.1, SHFM2 at Xq26, SHFM3 at 10q24q25, SHFM4 at 3q27), and two genes are known (DSS1 for SHFM1, p63 for SHFM4). We report the case of a 33 year-old female affected with the association of ectrodactyly and phocomelia. It could be a "new" association, or a mild or partial expression of the syndrome Including ectrodactyly, phocomelia, deafness and sinusal arythmia...
2002: Genetic Counseling
M Javorka, I Zila, K Javorka, A Calkovská
The aim of this study was to ascertain the persistence of heart rate and blood pressure oscillations at the onset of voluntary apnea in humans and to assess the dependence of the fluctuations parameters on the chemoreceptor activity. In 24 young subjects (10 males, 14 females, mean age 20.4 years) heart rate (represented by its reciprocal value--RR-intervals), systolic blood pressure (SBP) and diastolic blood pressure (DBP) during controlled breathing (CB) of atmospheric air and oxygen followed by apnea were recorded continuously...
2002: Physiological Research
G Matsumiya, S Ohtake, Y Sawa, T Takahashi, M Nishimura, K Kagizaki, T Katsura, H Matsue, H Matsuda
The limitation and indication of off-pump coronary artery bypass grafting (OPCAB) remain controversial. Since May 1999, we have applied OPCAB for all isolated coronary bypass cases routinely. Intraoperative conversion to CCAB occurred in 8 patients (10.8%). The main reasons for conversion were intramyocardial coronary arteries and arythmia-induced hemodynamic instability in the acute phase of myocardial infarction. We evaluated the results of OPCAB as compared to conventional coronary artery bypass (CCAB) as a historical control...
April 2001: Kyobu Geka. the Japanese Journal of Thoracic Surgery
F Combemale, B Carnaille, B Tavernier, M B Hautier, A Thevenot, P Scherpereel, C Proye
The pre and intraoperative use of calcium channel blockers (CCB) has been suggested for the management of either eutopic or ectopic pheochromocytomas. We report our experience of 70 pheochromocytomas, operated between 1988 and 1996 and managed with CCB, especially nicardipine. 59 were hypertensive (84.2%). Preparation consisted of nicardipine in 61 patients or another CCB in 9 cases with duration ranging from 24 hours to several weeks depending on plasma volume and blood pressure control. Intraoperatively, nicardipine infusion was started after intubation, adjusted according to systolic blood pressure (SBP) and stopped before ligation of the tumor venous drainage...
1998: Annales de Chirurgie
S Bagnulo, A M Giannini, F Moscatelli, L Stragapede, A Acquafredda, A Dammacco
We evaluated therapy complications in 19 beta-thalassemia major patients (mean age from 3 years/5 months and 1 years/6 months) who were followed at II Pediatric Department-University of Bari. 3 out of 19 patients underwent allogenic BMT from matched related donor; 2 out of 19 underwent splenectomy. All of them were receiving hypertransfusion therapy and continuous chelation with DFO. In all patients we performed physical examination, laboratory assays, cardiac and endocrinologic function tests, serum HBV-HCV-HIV antibodies, otoscopy and audiometric test, fundus oculi, skeletal x-ray...
January 1998: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
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