Wasim S El Nekidy, Khaled Al Zaman, Emna Abidi, Diaa Alrahmany, Islam M Ghazi, Rania El Lababidi, Mohamad Mooty, Fadi Hijazi, Muriel Ghosn, Mohamed Askalany, Mohamed Helal, Ahmed Taha, Khaled Ismail, Jihad Mallat
Background : The clinical outcomes of usual doses of Trimethoprim-sulfamethoxazole (TMP/SMZ) for treating S. maltophilia in critically ill patients on renal replacement therapies (RRT) have not been established. We sought to assess the clinical outcomes of TMP/SMZ in patients with sepsis utilizing RRT. Methods : A retrospective study was performed on all critically ill adult patients with S. maltophilia infections who received RRT between May 2015 and January 2022. The primary endpoint was clinical cure while the secondary endpoints were microbiologic cure, 30-day infection recurrence, and mortality...
April 14, 2024: Journal of Clinical Medicine