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Flora Pirozzi, Antonella Paglia, Laura Sasso, Pasquale Abete, Angelo Carlomagno, Carlo G Tocchetti, Domenico Bonaduce, Mario Petretta
OBJECTIVE: Doppler derived mitral peak early diastolic filling velocity to deceleration time ratio (E/DT) has been proposed as parameter for predicting prognosis in general population. This study prospectively investigates the incremental prognostic value of E/DT over clinical, conventional echocardiographic and mitral-Doppler variables in patients hospitalized for decompensated heart failure (HF). METHODS: We analyzed 95 HF patients (mean age 64.8 ± 12.2 years) hospitalized at our institution from January 2010 to March 2012...
July 2015: Journal of Geriatric Cardiology: JGC
Rebekka Lytzen, Morten Helvind, Finn Stener Jørgensen, Connie Jørgensen, Wolfgang Arzt, Gerald Tulzer, Niels Vejlstrup
In-utero treatment of fetal aortic stenosis (AS) may prevent hypoplastic left heart syndrome. A girl was diagnosed prenatally with severe AS and was referred to the Women's and Children's Hospital in Linz, Austria, where she underwent an intrauterine valvuloplasty of the aortic valve. Postnatally, the girl was given prostaglandin and operated a.m. Ross-Konno. An echocardiography at the age of four months showed a neoaorta without stenosis and insufficiency and a normal systolic function of the left ventricle...
January 26, 2015: Ugeskrift for Laeger
María Luaces Méndez, Isidre Vilacosta, Cristina Sarriá, Cristina Fernández, José A San Román, Juan V Sanmartín, Javier López, Enrique Rodríguez
INTRODUCTION AND OBJECTIVES: Among the complications of infective endocarditis, systemic enbolisms are an ominous prognostic sign. The aim of the present study was to compare the demographic, clinical, microbiologic, and echocardiographic features of episodes of endocarditis accompanied and unaccompanied by embolisms in the spleen, kidney or liver. We also assessed the prognostic impact of these embolisms. MATERIAL AND METHOD: Prospective, multicenter clinical cohort study...
December 2004: Revista Española de Cardiología
Su-Zhen Dong, Ming Zhu, Fen Li
BACKGROUND: The cardiovascular system is the part of the fetal anatomy that most frequently suffers from congenital pathology. This study shows our preliminary experience with fetal cardiovascular magnetic resonance (CMR) to evaluate congenital cardiovascular abnormalities. METHODS: Between January 2006 and June 2011, Prenatal routine obstetric ultrasound (US), echocardiography and CMR data from 68 pregnant women carrying fetuses with congenital cardiovascular anomalies were compared with postnatal diagnoses (postnatal imagings, surgery and autopsy)...
2013: Journal of Cardiovascular Magnetic Resonance
George Andrikopoulos, Spiros Kourouklis, Chrysanthi Trika, Stylianos Tzeis, Ioannis Rassias, Christos Papademetriou, Apostolos Katsivas, George Theodorakis
A 44-year-old male patient with known Becker muscular dystrophy and concomitant non-ischemic dilated cardiomyopathy presented to our department because of worsening heart failure and presyncope. Upon admission, the patient was in New York Heart Association functional class III despite optimal pharmacological treatment; his ECG showed sinus rhythm with left bundle branch block and a wide QRS complex. Non-sustained ventricular tachycardia was recorded during 24-hour Holter monitoring. A complete three-dimensional echocardiographic study was performed and documented the dilatation and concomitant hypertrabeculation of the left ventricle (LV), with severely depressed systolic LV performance (ejection fraction 20%), as well as mechanical dyssynchrony--mainly in terms of intraventricular delay...
May 2013: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
Gaoli Liu, Yanli Qiao, Liming Ma, Liangchun Ni, Shanguang Zeng, Qingchen Li
BACKGROUND: More and more surgeons and patients focus on the minimally invasive surgical techniques in the 21st century. Totally thoracoscopic operation provides another minimal invasive surgical option for patients with ASD (atrial septal defect). In this study, we reported our experience of 61 patients with atrial septal defect who underwent totally thoracoscopic operation and discussed the feasibility and safety of the new technique. METHODS: From January 2010 to October 2012, 61 patients with atrial septal defect underwent totally thoracoscopic closure but not traditional median sternotomy surgery...
2013: Journal of Cardiothoracic Surgery
Michael F Hill, Amish V Patel, Abigail Murphy, Holly M Smith, Cristi L Galindo, Laura Pentassuglia, Xuyang Peng, Carrie G Lenneman, Oghenerukevwe Odiete, David B Friedman, Marvin W Kronenberg, Siyuen Zheng, Zhongming Zhao, Yanna Song, Frank E Harrell, Maya Srinivas, Anindita Ganguly, Jennifer Iaci, Tom J Parry, Anthony O Caggiano, Douglas B Sawyer
AIMS: Recombinant Neuregulin (NRG)-1β has multiple beneficial effects on cardiac myocytes in culture, and has potential as a clinical therapy for heart failure (HF). A number of factors may influence the effect of NRG-1β on cardiac function via ErbB receptor coupling and expression. We examined the effect of the NRG-1β isoform, glial growth factor 2 (GGF2), in rats with myocardial infarction (MI) and determined the impact of high-fat diet as well as chronicity of disease on GGF2 induced improvement in left ventricular systolic function...
2013: PloS One
Julia Zöllner, Ruth Curry, Mark Johnson
PURPOSE OF REVIEW: Heart disease is a leading cause of maternal death worldwide. In western countries, the principal causes of death from heart disease are myocardial infarction, cardiomyopathy and congenital heart disease, whereas in developing countries, rheumatic heart disease and its long-term consequences are more important. RECENT FINDINGS: There are few prospective studies upon which to base the management of these complex cases. However, best practice includes the assessment of women prepregnancy by a multidisciplinary team, with the aim of optimizing the clinical state, changing therapy to avoid teratogenic treatments and advising the patient and her relatives about the potential risks and possible complications that may arise...
April 2013: Current Opinion in Obstetrics & Gynecology
Ladan Taheri, Masoumeh Sadeghi, Hamid Sanei, Katayoun Rabiei, Somayeh Arabzadeh, Nizal Sarrafzadegan
BACKGROUND: Lead contamination can affect many body organs including the heart. This study assessed a number of echocardiographic indices to clarify the effects of lead on cardiac function among battery factory workers who are in constant exposure to lead. METHODS: In a cross-sectional study, 142 male battery factory workers who had been exposed to lead for at least 1 year were evaluated. The subjects aged 25-55 years old and were excluded if they had hypertension, diabetes, or cardiovascular diseases...
2012: ARYA Atherosclerosis
Haruchika Masuda, Hiroto Iwasaki, Atsuhiko Kawamoto, Hiroshi Akimaru, Masakazu Ishikawa, Masaaki Ii, Tomoko Shizuno, Atsuko Sato, Rie Ito, Miki Horii, Hideyuki Ishida, Shunichi Kato, Takayuki Asahara
Quantitative and qualitative impairment of endothelial progenitor cells (EPCs) limits the efficacy of autologous cell therapy in patients with cardiovascular diseases. Here, we developed a serum-free quality and quantity control culture system for colony-forming EPCs to enhance their regenerative potential. A culture with serum-free medium containing stem cell factor, thrombopoietin, vascular endothelial growth factor, interleukin-6, and Flt-3 ligand was determined as optimal quality and quantity culture (QQc) in terms of the most vasculogenic colony-forming EPC expansion, evaluated by the newly established EPC colony formation assay...
February 2012: Stem Cells Translational Medicine
I M Khomaziuk, Zh M Habulavichene, V A Khomaziuk
Particularities and clinical importance of the structural and functional changes of myocardium were estimated in Chernobyl disaster clean-up workers with atrial fibrillation (AF). We examined 122 men with AF, which was associated with ischemic heart disease and arterial hypertension. Paroxysmal AF was diagnosed in 42 patients, 80 patients had permanent AE Control group comprised 80 men without AF. Echocardiography and Doppler studies were performed using ultrasound scanner Aloka SSD-630 (Japan). Significant structural and functional changes of the heart were revealed already in paroxysmal AF and became more pronounced in permanent AF...
July 2011: Likars'ka Sprava
Nir N Somekh, Ali Haider, Amgad N Makaryus, Stanley Katz, Steven Bello, Alan Hartman
The left circumflex coronary artery is susceptible to injury during mitral valve surgery because of its proximity to the mitral valve annulus. We report the case of a 73-year-old woman who had undergone mitral valve repair and experienced a perioperative myocardial infarction due to occlusion of the left circumflex coronary artery. After percutaneous coronary intervention, a fistulous communication had developed between the stented portion of the left circumflex coronary artery and the left atrium, which, to our knowledge, is the first report of such a complication...
2012: Texas Heart Institute Journal
Marek Maciejewski, Katarzyna Piestrzeniewicz, Agata Bielecka-Dabrowa, Andrzej Walczak
INTRODUCTION: Patients with implanted bioprostheses are at risk of structural dysfunction which results from the limited durability of biological valves. The aim of this study was to analyse the mechanism of bioprosthesis degeneration and to evaluate the usability of transthoracic and transoesophageal echocardiography in determining the indications for reoperation in 117 patients with a bioprosthesis implanted before 65 years old. MATERIAL AND METHODS: The study comprised 117 consecutive patients (M - 27, F - 90, age 48-74 years, 57...
December 31, 2011: Archives of Medical Science: AMS
Marc J Gollub, Neety Panu, Holly Delaney, Michael Sohn, Junting Zheng, Chaya S Moskowitz, Jurgen Rademaker, Jennifer Liu
PURPOSE: To examine the accuracy of the cardiothoracic ratio (CTR) at routine computed tomography (CT) of the chest to diagnose cardiomegaly by using echocardiography (ECHO) as a criterion standard, and secondarily, to search for CT cardiac measurements correlating with left ventricular hypertrophy (LVH) at ECHO. MATERIALS AND METHODS: We searched 2 databases: cancer patients who had chest CT who also underwent routine ECHO by one experienced cardiologist, from January to March 2008...
January 2012: Journal of Computer Assisted Tomography
Kyriaki Papadopoulou-Legbelou, Efimia Papadopoulou-Alataki, Alexandra Fleva, Sofia Spanou, Aikaterini Pavlitou, George Varlamis
OBJECTIVE: To investigate cardiac complications in infectious mononucleosis patients and to associate them with biochemical and immunological parameters, as well as with spleen ultrasound findings. DESIGN: Cross-sectional study with follow-up. SETTING: Tertiary care pediatric unit, in the city of Thessaloniki, Greece. PARTICIPANTS AND INTERVENTIONS: Twenty-five children (15 boys, aged 1-11.6 years) suffering from infectious mononucleosis were studied during the acute phase and after 3-6 months...
March 2012: Indian Pediatrics
L Menegazzo, C Bussadori, D Chiavegato, C Quintavalla, V Bonfatti, C Guglielmini, E Sturaro, L Gallo, P Carnier
The aims of this study were to investigate the role and relative importance of auscultation and echocardiography traits as risk factors for the diagnosis of subaortic (SubAS) and pulmonic (PS) stenosis and to estimate the heritability (h(2)) of cardiac measurements taken through echocardiography for a random sample of Italian Boxer dogs. The data were cardiovascular examination results of 1,283 Italian Boxer dogs (686 females and 597 males) enrolled in the national screening program for heart defects arranged by the Italian Boxer Club...
February 2012: Journal of Animal Science
Stephen M Campbell, Ahmet Fuat, Nick Summerton, Neil Lancaster, Fd Richard Hobbs
BACKGROUND: Some UK GPs are acquiring access to natriuretic peptide (NP) testing or echocardiography as diagnostic tests for heart failure. This study developed appropriateness ratings for the diagnostic application of these tests in routine general practice. AIM: To develop appropriateness ratings for the diagnostic application of NP testing or echocardiography for heart failure in general practice. DESIGN AND SETTING: An appropriateness ratings evaluation in UK general practice...
July 2011: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Sarah Ham
Aortic dissection is a life-threatening condition with a 50% mortality rate in the first 48 hours and a 3-month mortality rate of 90% in untreated patients. Aortic dissection is a rare complication of pregnancy, but there is significant morbidity and mortality for the mother and infant. A 43-year-old woman with a 37-week intrauterine pregnancy was admitted to the emergency department 6 hours after the onset of tightness in her throat and neck pain. She described the pain as similar to pain she experienced with a myocardial infarction 2 years previously...
February 2010: AANA Journal
B H Jiang, J-C Tardif, Y Shi, J Dupuis
Pulmonary hypertension (PH) and right ventricular (RV) dysfunction associated with heart failure (HF) carry a poor prognosis. Although endothelin receptor antagonists (ERAs) demonstrated benefits in pulmonary arterial hypertension, their efficacy in PH associated with HF was not specifically evaluated. 2 weeks after myocardial infarction (MI) rats received bosentan (100 or 200 mg·kg(-1)·day(-1)) or no treatment for 3 weeks. PH, RV hypertrophy and function as well as lung remodeling and function were evaluated...
March 2011: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Ruo-yan Zhu, Li-chan Li, Rui-yu Chen, Li-ye Shi, Jian-mei Niu, Xiao Wang, Jin-jin Wang
OBJECTIVE: To evaluate the prenatal diagnostic accuracy of fetal echocardiography for congenital heart defects. METHODS: Fetal echocardiographic databases from 2001 to 2007 were searched for patients with a prenatal diagnosis of congenital heart defect, medical records were obtained and the prenatal echocardiographic findings were correlated with postnatal echocardiography results or autopsy findings, if the pregnancy was terminated or the fetus died in utero. RESULTS: Prenatal diagnosis of congenital heart defects was made in 113 pregnancies at a mean gestational age of 26...
April 2009: Zhonghua Xin Xue Guan Bing za Zhi
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