Rachel Bolton, Moritz M Machelett, Jack Stubbs, Danny Axford, Nicolas Caramello, Lucrezia Catapano, Martin Malý, Matthew J Rodrigues, Charlotte Cordery, Graham J Tizzard, Fraser MacMillan, Sylvain Engilberge, David von Stetten, Takehiko Tosha, Hiroshi Sugimoto, Jonathan A R Worrall, Jeremy S Webb, Mike Zubkov, Simon Coles, Eric Mathieu, Roberto A Steiner, Garib Murshudov, Tobias E Schrader, Allen M Orville, Antoine Royant, Gwyndaf Evans, Michael A Hough, Robin L Owen, Ivo Tews
The marine cyanobacterium Prochlorococcus is a main contributor to global photosynthesis, whilst being limited by iron availability. Cyanobacterial genomes generally encode two different types of FutA iron-binding proteins: periplasmic FutA2 ABC transporter subunits bind Fe(III), while cytosolic FutA1 binds Fe(II). Owing to their small size and their economized genome Prochlorococcus ecotypes typically possess a single futA gene. How the encoded FutA protein might bind different Fe oxidation states was previously unknown...
March 19, 2024: Proceedings of the National Academy of Sciences of the United States of America