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Belle's palsy

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https://www.readbyqxmd.com/read/29343258/mass-spectrometric-profiling-of-cerebrospinal-fluid-reveals-metabolite-biomarkers-for-cns-involvement-in-varicella-zoster-virus-reactivation
#1
Maike Kuhn, Kurt-Wolfram Sühs, Manas K Akmatov, Frank Klawonn, Junxi Wang, Thomas Skripuletz, Volkhard Kaever, Martin Stangel, Frank Pessler
BACKGROUND: Varicella zoster virus (VZV) reactivation spans the spectrum from uncomplicated segmental herpes zoster to life-threatening disseminated CNS infection. Moreover, in the absence of a small animal model for this human pathogen, studies of pathogenesis at the organismal level depend on analysis of human biosamples. Changes in cerebrospinal fluid (CSF) metabolites may reflect critical aspects of host responses and end-organ damage in neuroinfection and neuroinflammation. We therefore applied a targeted metabolomics screen of CSF to three clinically distinct forms of VZV reactivation and infectious and non-infectious disease controls in order to identify biomarkers for CNS involvement in VZV reactivation...
January 17, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29301560/delayed-facial-nerve-decompression-for-severe-refractory-cases-of-bell-s-palsy-a-25-year-experience
#2
Ilyes Berania, Mohamed Awad, Issam Saliba, Jean-Jacques Dufour, Marc-Elie Nader
BACKGROUND: This study aims to assess the effectiveness of delayed facial nerve decompression for Bell's palsy (BP). METHODS: We performed a retrospective case review of all patients having undergone facial nerve decompression for severe refractory BP between 1984 and 2009 at our tertiary referral center. Demographics, timing between onset of symptoms and surgical decompression, degree of facial nerve dysfunction pre- and post-operatively, follow-up length after surgery and postoperative complications were recorded...
January 4, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29284561/does-type-2-diabetes-mellitus-affect-the-healing-of-bell-s-palsy-in-adults
#3
Sultan Şevik Eliçora, Duygu Erdem
OBJECTIVES: Bell's palsy (BP) is defined as an acute facial weakness of unknown cause. Many factors affecting the healing of BP have been identified; 1 factor commonly considered relevant is the presence of type 2 diabetes mellitus. Our aim was to investigate the effects of diabetes on the healing of BP. METHODS: Sixty patients with BP were followed up for 1 to 3 years and were divided into 2 groups, those with and those without type 2 diabetes. All were prescribed prednisone (initially 1 mg/kg per day, with a tapered dose reduction) and acyclovir (200 mg orally every 4 h, 5 times daily, for 5 days)...
December 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29283103/a-view-of-the-therapy-for-bell-s-palsy-based-on-molecular-biological-analyses-of-facial-muscles
#4
Hiroshi Moriyama, Nobuyuki Mitsukawa, Masahiro Itoh, Naruhito Otsuka
OBJECTIVE: Details regarding the molecular biological features of Bell's palsy have not been widely reported in textbooks. We genetically analyzed facial muscles and clarified these points. MATERIALS AND METHODS: We performed genetic analysis of facial muscle specimens from Japanese patients with severe (House-Brackmann facial nerve grading system V) and moderate (House-Brackmann facial nerve grading system III) dysfunction due to Bell's palsy. Microarray analysis of gene expression was performed using specimens from the healthy and affected sides, and gene expression was compared...
December 14, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29250758/refractory-facial-paralysis-a-case-report
#5
Yu-Wei Hsu, Jiunn-Tay Lee, Yi-Shu Liao, Shin Nieh, Chun-An Cheng, Chia-Kuang Tsai
PURPOSE: To present a case of salivary gland malignancy initially mimicking Bell's palsy. CASE REPORT: A 75-year-old woman with hypertension visited our neurological outpatient department,complaining of persistent right facial paralysis for more than a year after oral glucocorticoid therapy with recent development of vertigo and unsteady gait. She was previously diagnosed as having Bell's palsy and was prescribed oral glucocorticoid. However, her right facial muscles were still completely paralyzed, with no signs of improvement...
June 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/29237635/new-onset-bell-palsy-and-lyme-disease
#6
(no author information available yet)
No abstract text is available yet for this article.
December 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29232151/adjuvanted-influenza-vaccines
#7
John S Tregoning, Ryan F Russell, Ekaterina Kinnear
In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health. One approach to improve influenza vaccines is to include adjuvants; substances that boost the immune response. Adjuvants are particularly beneficial for influenza vaccines administered during a pandemic when a rapid response is required or for use in patients with impaired immune responses, such as infants and the elderly. This review outlines the current use of adjuvants in human influenza vaccines, including what they are, why they are used and what is known of their mechanism of action...
December 12, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29227146/time-dependent-recovery-of-human-synovial-membrane-mesenchymal-stem-cell-function-after-high-dose-steroid-therapy-case-report-and-laboratory-study
#8
Yukihiko Yasui, David A Hart, Norihiko Sugita, Ryota Chijimatsu, Kota Koizumi, Wataru Ando, Yu Moriguchi, Kazunori Shimomura, Akira Myoui, Hideki Yoshikawa, Norimasa Nakamura
BACKGROUND: The use of mesenchymal stem cells from various tissue sources to repair injured tissues has been explored over the past decade in large preclinical models and is now moving into the clinic. PURPOSE: To report the case of a patient who exhibited compromised mesenchymal stem cell (MSC) function shortly after use of high-dose steroid to treat Bell's palsy, who recovered 7 weeks after therapy. STUDY DESIGN: Case report and controlled laboratory study...
December 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29216223/increased-risk-of-peripheral-arterial-occlusive-disease-in-patients-with-bell-s-palsy-using-population-data
#9
Li-Syue Liou, Chih-Ya Chang, Hsuan-Ju Chen, Chun-Hung Tseng, Cheng-Yu Chen, Fung-Chang Sung
OBJECTIVE: This population-based cohort study investigated the risk of developing peripheral arterial occlusive disease (PAOD) in patients with Bell's palsy. METHODS: We used longitudinal claims data of health insurance of Taiwan to identify 5,152 patients with Bell's palsy newly diagnosed in 2000-2010 and a control cohort of 20,608 patients without Bell's palsy matched by propensity score. Incidence and hazard ratio (HR) of PAOD were assessed by the end of 2013...
2017: PloS One
https://www.readbyqxmd.com/read/29191062/recurrent-bell-s-palsy-following-ventriculoperitoneal-shunt-insertion-an-unusual-case-to-face
#10
Ashwin Kumaria, Tim C Hammett, Murugan Sitaraman, Dan A D'Aquino, Donald C Macarthur
We present the case of a 15 year old boy who developed transient lower motor neuron facial weakness on two separate occasions shortly after ventriculoperitoneal shunt insertion. Both episodes, each of which occurred on the ipsilateral side to shunt insertion, were transient, self-limiting and were managed medically with a course of oral steroids. We believe this is the first reported case of Bell's palsy after this type of surgery in a child. Potential pathophysiological mechanisms are discussed.
November 30, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29172335/facial-palsy-masquerading-as-an-acute-dental-abscess
#11
Arif Razzak, Frances O’Leary, Nabeela Ahmed
Facial nerve palsy has specific symptomology, but varied aetiology. Prompt and thorough assessment is required to ascertain if upper or lower motor neurone damage has occurred. This report discusses a 6-year-old female, presenting in the Emergency Department with unilateral facial weakness. Initially thought to be facial swelling relating to her carious dentition, clinical assessment from the maxillofacial team identified that the patient had a unilateral facial palsy, later diagnosed as Bell’s palsy. Her delayed presentation was due to initial misdiagnoses in primary care...
March 2017: Dental Update
https://www.readbyqxmd.com/read/29167377/oropharyngeal-dysphagia-and-cerebral-palsy
#12
Katherine A Benfer, Kelly A Weir, Kristie L Bell, Robert S Ware, Peter S W Davies, Roslyn N Boyd
OBJECTIVES: To determine the progression of oropharyngeal dysphagia (OPD) in preschool-aged children with cerebral palsy (CP) according to gross motor function. It was hypothesized that fewer children would have OPD at 60 months compared with 18 to 24 months (predominately Gross Motor Function Classification System [GMFCS] I-II). METHODS: Longitudinal population-based cohort of 179 children (confirmed CP diagnosis, born in Queensland in 2006-2009, aged 18-60 months at study entry [mean = 34...
November 22, 2017: Pediatrics
https://www.readbyqxmd.com/read/29164322/prevalence-and-characteristics-of-hearing-loss-in-patients-diagnosed-with-bell-s-palsy
#13
Tomer Maller, Sonia Goldenstein, Ohad Ronen
OBJECTIVES: To assess the incidence of hearing loss in patients diagnosed with Bell's palsy (BP) and to characterize its clinical features. DESIGN: Patients with BP who underwent audiometry testing in our institute were included. Bone hearing level differences between the ipsilateral and the contralateral ears to the palsied side were calculated for 6 frequencies: 250, 500, 1000, 2000, 4000 and 8000 Hz. Subjects with interaural differences higher than 5 dB in at least one frequency were considered as having ipsilateral unilateral sensorineural hearing loss (uSNHL)...
November 21, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29154053/acupuncture-and-kinesio-taping-for-the-acute-management-of-bell-s-palsy-a-case-report
#14
Derya Özmen Alptekin
BACKGROUND: Bell's palsy is an idiopathic, acute peripheral palsy of the facial nerve that supplies the muscles of facial expression. Despite an expected 70% full recovery rate, up to 30% of patients are left with potentially disfiguring facial weakness, involuntary movements, or persistent lacrimation. The most frequently used treatment options are corticosteroids and antiviral drugs. However, accompanying clinical conditions, such as uncontrolled diabetes, hypertension, gastrointestinal disturbances, polypharmacy of geriatric patients, and significant sequelae ratios, indicate the need for safe and effective complementary therapies that would enhance the success of the conventional interventions...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29152808/observational-safety-study-of-specific-outcomes-after-trivalent-cell-culture-seasonal-influenza-vaccination-optaflu-%C3%A2-among-adults-in-thin-database-of-electronic-uk-primary-healthcare-records
#15
Gillian C Hall, Paul T G Davies, M Yousuf Karim, Mendel D M Haag, Caroline O'Leary
PURPOSE: To investigate the safety of trivalent seasonal influenza vaccine (TIVc) (Optaflu(®) ), the first cell culture seasonal trivalent influenza vaccine available in Europe. METHODS: Codes and unstructured text in adult electronic healthcare records (The Health Improvement Network) were searched for a TIVc brand name or batch number and possible outcomes within a 3 month pre- to 6 month post-TIVc exposure study period (2012-2015). The outcomes were severe allergic reactions, Bell's palsy, convulsions, demyelination, paresthesia, noninfectious encephalitis, neuritis (optic and brachial), vasculitis, inflammatory bowel disease, and thrombocytopenia...
November 20, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29144221/a-case-of-bell-s-palsy-complicated-by-subsequent-herpes-simplex-virus-encephalitis
#16
Margaret Moores, Caroline Nott
No abstract text is available yet for this article.
November 16, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29135869/usefulness-of-high-resolution-3d-multi-sequences-for-peripheral-facial-palsy-differentiation-between-bell-s-palsy-and-ramsay-hunt-syndrome
#17
Junko Kuya, Keita Kuya, Yuki Shinohara, Yasuomi Kunimoto, Hiroaki Yazama, Toshihide Ogawa, Hiromi Takeuchi
OBJECTIVE: To investigate the usefulness of magnetic resonance imaging (MRI) including three-dimensional (3D) sequences in the differentiation between Bell's palsy (BP) and Ramsay Hunt syndrome (RHS). STUDY DESIGN: A prospective study. SETTING: Tertiary care center. PATIENTS: Twenty patients: 15 patients with BP and five patients with RHS. INTERVENTION: Diagnostic. MAIN OUTCOME MEASURE: Clinical diagnosis (BP or RHS)...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29132189/-from-the-expert-s-office-examination-of-bell-s-palsy-in-consideration-of-the-austrian-private-accident-insurance
#18
Wolfgang Willibald Kuchler
No abstract text is available yet for this article.
November 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29109140/teaching-neuroimages-sucking-candy-sign-in-bell-palsy
#19
Cynthia E Armand, Matthew S Robbins
No abstract text is available yet for this article.
November 7, 2017: Neurology
https://www.readbyqxmd.com/read/29065089/high-incidence-of-bell-s-palsy-after-mastoidectomy-a-longitudinal-follow-up-study
#20
Hyo Geun Choi, Songyong Sim, Sung Kwang Hong, Su-Kyoung Park, Hyo-Jeong Lee, Jiwon Chang
OBJECTIVE: The objective of this study was to compare the prevalence of Bell's palsy in participants who underwent mastoidectomy (to treat chronic otitis media) and nonmastoidectomy participants (control). METHODS: Using the national cohort study from the Korean Health Insurance Review and Assessment Service, mastoidectomy patients (2,045) and control participants (8,180) were matched 1:4 for age, sex, income, and region of residence. The prevalence of Bell's palsy in both the groups was measured from 0 to 10 years postoperation...
December 2017: Otology & Neurotology
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