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Belle's palsy

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https://www.readbyqxmd.com/read/28299208/sensorimotor-cortical-neuroplasticity-in-the-early-stage-of-bell-s-palsy
#1
Wenwen Song, Minhui Dai, Lihua Xuan, Zhijian Cao, Sisi Zhou, Courtney Lang, Kun Lv, Maosheng Xu, Jian Kong
Neuroplasticity is a common phenomenon in the human brain following nerve injury. It is defined as the brain's ability to reorganize by creating new neural pathways in order to adapt to change. Here, we use task-related and resting-state fMRI to investigate neuroplasticity in the primary sensory (S1) and motor cortex (M1) in patients with acute Bell's palsy (BP). We found that the period directly following the onset of BP (less than 14 days) is associated with significant decreases in regional homogeneity (ReHo), fractional amplitude of low frequency fluctuations (fALFF), and intrinsic connectivity contrast (ICC) values in the contralateral S1/M1 and in ReHo and ICC values in the ipsilateral S1/M1, compared to healthy controls...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28293309/neutrophil-to-lymphocyte-ratio-platelet-to-lymphocyte-ratio-mean-platelet-volume-and-red-cell-distribution-width-measures-in-bells-palsy
#2
Caner Sahin, Ceyhun Varım
AIM: The purpose of this study was to investigate the usefulness of the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) Mean Platelet Volume (MPV) and Red Cell Distribution Width (RDW) in the differential diagnosis and follow-up of patients with Bells Palsy. MATERIAL AND METHODS: Twenty-eight patients diagnosed with Bells Palsy and 28 control patients were included in the study. Serum samples were analysed retrospectively on the initial presentation and the seventh day of admission...
March 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28276586/the-eating-and-drinking-ability-classification-system-in-a-population-based-sample-of-preschool-children-with-cerebral-palsy
#3
Katherine A Benfer, Kelly A Weir, Kristie L Bell, Robert S Ware, Peter Sw Davies, Roslyn N Boyd
AIM: To determine (1) the reproducibility of the Eating and Drinking Ability Classification System (EDACS); (2) EDACS classification distribution in a population-based cohort with cerebral palsy (CP); and (3) the relationships between the EDACS and clinical mealtime assessment, other classifications, and health outcomes. METHOD: This was a cross-sectional population-based cohort study of 170 children with CP at 3 years to 5 years (mean 57.6mo, standard deviation [SD] 8...
March 9, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28246588/intermittent-facial-spasms-as-the-presenting-sign-of-a-recurrent-pleomorphic-adenoma
#4
Rosalie A Machado, Sami P Moubayed, Azita Khorsandi, Juan C Hernandez-Prera, Mark L Urken
The intimate anatomical relationship of the facial nerve to the parotid parenchyma has a significant influence on the presenting signs and symptoms, diagnosis and treatment of parotid neoplasms. However, to our knowledge, hyperactivity of this nerve, presenting as facial spasm, has never been described as the presenting sign or symptom of a parotid malignancy. We report a case of carcinoma arising in a recurrent pleomorphic adenoma of the left parotid gland (i.e., carcinoma ex pleomorphic adenoma) that presented with hemifacial spasms...
February 10, 2017: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28222241/novel-pre-therapeutic-scoring-system-using-patient-and-hematological-data-to-predict-facial-palsy-prognosis
#5
Koichiro Wasano, Toru Ishikawa, Taiji Kawasaki, Sayuri Yamamoto, Shuta Tomisato, Seiichi Shinden, Shujiro Minami, Takeshi Wakabayashi, Kaoru Ogawa
OBJECTIVES: We describe a novel scoring system, the facial Palsy Prognosis Prediction score (PPP score), which we test for reliability in predicting pre-therapeutic prognosis of facial palsy. We aimed to use readily available patient data that all clinicians have access to before starting treatment. DESIGN: Multicenter case series with chart review. SETTING: Three tertiary care hospitals. PARTICIPANTS: We obtained hematological and demographic data from 468 facial palsy patients who were treated between 2010 and 2014 in three tertiary care hospitals...
February 21, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28197706/efficacy-of-the-red-blood-cell-distribution-width-for-predicting-the-prognosis-of-bell-palsy-a-pilot-study
#6
Yuichiro Horibe, Tohru Tanigawa, Rei Shibata, Hiroshi Nonoyama, Fumiya Kano, Satoshi Yamaguchi, Kenta Murotani, Takaki Ogawa, Hiromi Ueda
The aim of this study was to investigate the association between RDW values and the prognosis of patients with Bell palsy in an effort to find a prognostic biomarker that predicts recovery from Bell palsy. We measured RDW and evaluated facial movement in 61 patients with Bell palsy aged 50 years and less. All patients were treated with a steroid plus an antiviral agent. Seven patients underwent surgery for facial nerve decompression. During the post-treatment period, patients with a Yanagihara grading score of 36 or more were regarded as having a satisfactory recovery...
February 14, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28193257/bell-s-palsy-in-children-bellpic-protocol-for-a-multicentre-placebo-controlled-randomized-trial
#7
Franz E Babl, Mark T Mackay, Meredith L Borland, David W Herd, Amit Kochar, Jason Hort, Arjun Rao, John A Cheek, Jeremy Furyk, Lisa Barrow, Shane George, Michael Zhang, Kaya Gardiner, Katherine J Lee, Andrew Davidson, Robert Berkowitz, Frank Sullivan, Emily Porrello, Kim Marie Dalziel, Vicki Anderson, Ed Oakley, Sandy Hopper, Fiona Williams, Catherine Wilson, Amanda Williams, Stuart R Dalziel
BACKGROUND: Bell's palsy or acute idiopathic lower motor neurone facial paralysis is characterized by sudden onset paralysis or weakness of the muscles to one side of the face controlled by the facial nerve. While there is high level evidence in adults demonstrating an improvement in the rate of complete recovery of facial nerve function when treated with steroids compared with placebo, similar high level studies on the use of steroids in Bell's palsy in children are not available. The aim of this study is to assess the utility of steroids in Bell's palsy in children in a randomised placebo-controlled trial...
February 13, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28180070/disrupted-functional-connectivity-of-striatal-sub-regions-in-bell-s-palsy-patients
#8
Wenwen Song, Zhijian Cao, Courtney Lang, Minhui Dai, Lihua Xuan, Kun Lv, Fangyuan Cui, Kristen Jorgenson, Maosheng Xu, Jian Kong
The striatum plays an important role in controlling motor function in humans, and its degeneration has the ability to cause severe motor disorders. More specifically, previous studies have demonstrated a disruption in the connectivity of the cortico-striatal loop in patients suffering from motor disorders caused by dopamine dysregulation, such as Parkinson's disease. However, little is known about striatal functional connectivity in patients with motor dysfunction not caused by dopamine dysregulation. In this study, we used early-state Bell's palsy (BP) patients (within 14 days of onset) to investigate how functional connectivity between the striatum and motor cortex is affected by peripheral nerve injury in which the dopamine system remains fully functional...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28178096/relative-location-of-fundus-meatus-acustici-interni-via-porus-acusticus-internus-in-facial-nerve-decompression
#9
Xu Liu, Haodong Wang, Kailiang Cheng, Youqiong Li
Facial neural edema is the pathophysiological base of Bell's palsy. The middle cranial fossa approach is used to relieve the oppression of facial nerve at its most narrow course in the facial canal. In this research, the authors mainly discussed the internal auditory canal segment of facial nerve, completely in the shadow of the bony structure, which is inconvenient for transmastoid decompression. Therefore, the objective was to explore the definite position of the fundus meatus acustici interni from internal acoustic pore...
February 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28177168/bell-s-palsy-in-children-current-treatment-patterns-in-australia-and-new-zealand-a-predict-study
#10
Franz E Babl, Kaya K Gardiner, Amit Kochar, Catherine L Wilson, Shane A George, Michael Zhang, Jeremy Furyk, Deepali Thosar, John A Cheek, David Krieser, Arjun S Rao, Meredith L Borland, Nicholas Cheng, Natalie T Phillips, Kam K Sinn, Jocelyn M Neutze, Stuart R Dalziel
AIM: The aetiology and clinical course of Bell's palsy may be different in paediatric and adult patients. There is no randomised placebo controlled trial (RCT) to show effectiveness of prednisolone for Bell's palsy in children. The aim of the study was to assess current practice in paediatric Bell's palsy in Australia and New Zealand Emergency Departments (ED) and determine the feasibility of conducting a multicentre RCT within the Paediatric Research in Emergency Departments International Collaborative (PREDICT)...
February 8, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28168888/cutaneous-sensibility-changes-in-bell-s-palsy-patients
#11
Carlos Andrés Cárdenas Palacio, Francisco Alejandro Múnera Galarza
Objective Bell's palsy is a cranial nerve VII dysfunction that renders the patient unable to control facial muscles from the affected side. Nevertheless, some patients have reported cutaneous changes in the paretic area. Therefore, cutaneous sensibility changes might be possible additional symptoms within the clinical presentation of this disorder. Accordingly, the aim of this research was to investigate the relationship between cutaneous sensibility and facial paralysis severity in these patients. Study Design Prospective longitudinal cohort study...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28162825/safety-of-quadrivalent-live-attenuated-influenza-vaccine-in-subjects-aged-2-49years
#12
Roger Baxter, Abigail Eaton, John Hansen, Laurie Aukes, Herve Caspard, Christopher S Ambrose
BACKGROUND: Quadrivalent live attenuated influenza vaccine (Q/LAIV) was licensed in 2012 and replaced trivalent live attenuated influenza vaccine in the United States during the 2013-2014 influenza season. This study assessed the safety of Q/LAIV in children and adults aged 2-49years. METHODS: This was a prospective observational cohort study using data collected from Kaiser Permanente Northern California. Post-vaccination events of interest were any hospitalization, hospitalization for lower respiratory tract infection, and the following medically attended events: hypersensitivity, seizures/convulsions, lower respiratory tract infection, wheezing, Guillain-Barré syndrome, Bell's palsy, encephalitis, neuritis, vasculitis, and narcolepsy/cataplexy...
March 1, 2017: Vaccine
https://www.readbyqxmd.com/read/28161243/facial-nerve-paralysis-associated-with-temporal-bone-masses
#13
Hironobu Nishijima, Kenji Kondo, Ryoji Kagoya, Hitoshi Iwamura, Kazuo Yasuhara, Tatsuya Yamasoba
OBJECTIVE: To investigate the clinical and electrophysiological features of facial nerve paralysis (FNP) due to benign temporal bone masses (TBMs) and elucidate its differences as compared with Bell's palsy. METHODS: FNP assessed by the House-Brackmann (HB) grading system and by electroneurography (ENoG) were compared retrospectively. RESULTS: We reviewed 914 patient records and identified 31 patients with FNP due to benign TBMs. Moderate FNP (HB Grades II-IV) was dominant for facial nerve schwannoma (FNS) (n=15), whereas severe FNP (Grades V and VI) was dominant for cholesteatomas (n=8) and hemangiomas (n=3)...
February 1, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28156036/assessing-recording-delays-in-general-practice-records-to-inform-near-real-time-vaccine-safety-surveillance-using-the-clinical-practice-research-datalink-cprd
#14
Andreia Leite, Nick J Andrews, Sara L Thomas
PURPOSE: Near real-time vaccine safety surveillance (NRTVSS) is an option for post-licensure vaccine safety assessment. NRTVSS requires timely recording of outcomes in the database used. Our main objective was to examine recording delays in the Clinical Practice Research Datalink (CPRD) for outcomes of interest for vaccine safety to inform the feasibility of NRTVSS using these data. We also evaluated completeness of recording and further assessed reporting delays for hospitalized events in CPRD...
February 3, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28141956/bell-s-facial-nerve-palsy-in-pregnancy-a-clinical-review
#15
Ahsen Hussain, Charles Nduka, Philippa Moth, Raman Malhotra
Bell's facial nerve palsy (FNP) during pregnancy and the puerperium can present significant challenges for the patient and clinician. Presentation and prognosis can be worse in this group of patients. This article reviews the background, manifestation and management options of FNP. In particular, it focuses on the controversies that exist regarding corticosteroid use during pregnancy and outlines approaches to diagnosis and treatment. Based on this review, we recommend an early evidence-based approach using guidelines derived from non-pregnant populations...
January 31, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28135303/microrna-and-mrna-transcriptome-profiling-in-primary-human-astrocytes-infected-with-borrelia-burgdorferi
#16
Timothy Casselli, Humaira Qureshi, Elizabeth Peterson, Danielle Perley, Emily Blake, Bradley Jokinen, Ata Abbas, Sergei Nechaev, John A Watt, Archana Dhasarathy, Catherine A Brissette
Lyme disease is caused by infection with the bacterium Borrelia burgdorferi (Bb), which is transmitted to humans by deer ticks. The infection manifests usually as a rash and minor systemic symptoms; however, the bacteria can spread to other tissues, causing joint pain, carditis, and neurological symptoms. Lyme neuroborreliosis presents itself in several ways, such as Bell's palsy, meningitis, and encephalitis. The molecular basis for neuroborreliosis is poorly understood. Analysis of the changes in the expression levels of messenger RNAs and non-coding RNAs, including microRNAs, following Bb infection could therefore provide vital information on the pathogenesis and clinical symptoms of neuroborreliosis...
2017: PloS One
https://www.readbyqxmd.com/read/28125753/photographic-standards-for-patients-with-facial-palsy-and-recommendations-by-members-of-the-sir-charles-bell-society
#17
Katherine B Santosa, Adel Fattah, Javier Gavilán, Tessa A Hadlock, Alison K Snyder-Warwick
Importance: There is no widely accepted assessment tool or common language used by clinicians caring for patients with facial palsy, making exchange of information challenging. Standardized photography may represent such a language and is imperative for precise exchange of information and comparison of outcomes in this special patient population. Objectives: To review the literature to evaluate the use of facial photography in the management of patients with facial palsy and to examine the use of photography in documenting facial nerve function among members of the Sir Charles Bell Society-a group of medical professionals dedicated to care of patients with facial palsy...
January 26, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28118632/bell-s-palsy-clinical-analysis-of-372-cases-and-review-of-related-literature
#18
Hua Zhao, Xin Zhang, Yin-da Tang, Jin Zhu, Xu-Hui Wang, Shi-Ting Li
OBJECTIVE: To analyze some clinical and epidemiologic aspects of Bell's palsy (BP) and to develop relevant correlations between existing data in literature and those obtained in this research. METHODS: From January 2012 to December 2014, 372 consecutive patients diagnosed with BP were studied retrospectively. We reviewed the patients' data including gender, age, occupation, clinical manifestations, comorbid disease, and the rate of recurrence. RESULT: The highest incidence was identified in those between 39 and 50 years of age...
2017: European Neurology
https://www.readbyqxmd.com/read/28115404/concurrent-pityriasis-rosea-and-bell-s-palsy
#19
Vanessa Voss, Adam Mattox, Mary Guo
Pityriasis rosea is a dermatological disease with a well-documented clinical appearance, but less is known about causes and treatment. Bell's palsy is a neurological condition leading to acute idiopathic hemifacial paralysis. Recent studies indicate that human herpesvirus (HHV) 6-7 reactivation may be a contributing factor to both conditions. We report a case of the 2 concurrent diagnoses that supports a common contributing factor and suggests further awareness and research into the role HHV 6-7 may play in the aetiology of both conditions...
January 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28112552/acupuncture-for-the-treatment-of-peripheral-neuropathy-a-systematic-review-and-meta-analysis
#20
Alexandra Dimitrova, Charles Murchison, Barry Oken
OBJECTIVES: Neuropathy and its associated pain pose great therapeutic challenges. While there has been a recent surge in acupuncture use and research, little remains known about its effects on nerve function. This review aims to assess the efficacy of acupuncture in the treatment of neuropathy of various etiologies. METHODS: The Medline, AMED, Cochrane, Scopus, CINAHL, and clintrials.gov databases were systematically searched from inception to July 2015. Randomized controlled trials (RCTs) assessing acupuncture's efficacy for poly- and mononeuropathy were reviewed...
March 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
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