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red blood cell distribution

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https://www.readbyqxmd.com/read/28102039/a-dispermic-chimerism-detected-in-a-taiwanese-potential-unrelated-hematopoietic-stem-cell-donor
#1
E K L Yang, S G E Marsh, P-Y Chen, C-P Chen, S-P Chen, P Y Lin
Chimerism is defined as the presence of 2 or more than 1 genetically distinct cell populations in an organism. Dispermic chimeras are derived from the fertilization of 1 or 2 matured nuclei by 2 sperms. We here report detection of a healthy and phenotypically normal female with normal ABO red blood cell typing in whom dispermic chimerism was suspected after 3 alleles were identified at multiple human leukocyte antigen (HLA) loci using molecular HLA analysis. Molecular HLA typing showed the donor to have 3 HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 alleles in blood, saliva and nail samples...
February 2017: HLA
https://www.readbyqxmd.com/read/28101125/preventive-transarterial-embolization-in-upper-nonvariceal-gastrointestinal-bleeding
#2
Aleksejs Kaminskis, Aina Kratovska, Sanita Ponomarjova, Anna Tolstova, Maksims Mukans, Solvita Stabiņa, Raivis Gailums, Andrejs Bernšteins, Patricija Ivanova, Viesturs Boka, Guntars Pupelis
BACKGROUND: Transarterial embolization (TAE) is a therapeutic option for patients with a high risk of recurrent bleeding after endoscopic haemostasis. The aim of our prospective study was a preliminary assessment of the safety, efficacy, and clinical outcomes following preventive TAE in patients with non-variceal acute upper gastrointestinal bleeding (NVUGIB) with a high risk of recurrent bleeding after endoscopic haemostasis. METHODS: Preventive visceral angiography and TAE were performed after endoscopic haemostasis on patients with NVUGIB who were at a high risk of recurrent bleeding (PE+ group)...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28098429/natural-history-of-nonimmune-mediated-thrombocytopenia-and-acute-kidney-injury-in-pediatric-open-heart-surgery
#3
Shannon Tew, Manuel L Fontes, Nathaniel H Greene, Miklos D Kertai, George Ofori-Amanfo, Robert D B Jaquiss, Andrew J Lodge, Warwick A Ames, Hercilia Mayumi Homi, Kelly A Machovec, Edmund H Jooste
OBJECTIVE: Thrombocytopenia and acute kidney injury (AKI) are common following pediatric cardiac surgery with cardiopulmonary bypass (CPB). However, the relationship between postoperative nadir platelet counts and AKI has not been investigated in the pediatric population. Our objective was to investigate this relationship and examine independent predictors of AKI. DESIGN: After IRB approval, we performed a retrospective review of the institution's medical records and database...
January 18, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28070471/importance-of-mean-red-cell-distribution-width-in-hypertensive-patients
#4
Ahmed Bilal, Junaid H Farooq, Immad Kiani, Salman Assad, Haider Ghazanfar, Imran Ahmed
PURPOSE: Red cell distribution width (RDW), expressed in femtoliters (fl), is a measure of the variation in the size of circulating erythrocytes and is often expressed as a direct measurement of the width of the distribution. We aim to observe the mean value of red cell distribution width (RDW) in hypertensive patients. Increased RDW can be used as a tool for early diagnosis, as an inflammatory marker, and a mortality indicator in hypertensive patients due to its close relation to inflammation...
November 29, 2016: Curēus
https://www.readbyqxmd.com/read/28066938/effect-of-gender-and-exercise-on-haematological-and-biochemical-parameters-in-holsteiner-horses
#5
A Andriichuk, H Tkachenko
The objective of this study was to assess the influence of exercise of average intensity in the haematological and biochemical values, as well as acidic resistance of erythrocytes in mares and stallions of Holsteiner breed. A total of seventeen horses of Holstein breed (seven mares and 10 stallions aged 6 years) were used in this study. The blood samples were assessed for haematocrit (HCT) value, haemoglobin concentration (HGB), the amount of red blood cells (RBC), white blood cells (WBC), platelets (PLT), leucogram, mean corpuscular haemoglobin concentration (MCHC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), red cell distribution width (RDW) and platelet distribution width (PDW)...
January 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28063061/isolation-and-characterization-of-aortic-dendritic-cells-and-lymphocytes-in-atherosclerosis
#6
Tae Jin Yun, Jun Seong Lee, Dahee Shim, Jae-Hoon Choi, Cheolho Cheong
Dendritic cells (DCs) are central to initiate antigen-specific immunity and tolerance. The in vivo development and distribution of DCs are now better understood even in nonlymphoid tissues [1]. Atherosclerosis is a chronic inflammatory disease of blood vessels and DCs are highly enriched in the intimal area of the aorta, which is predisposed to develop atherosclerosis. Previously, we were the first to show antigen presenting DCs and their subsets in the aorta [2, 3]. Here, we discuss several useful methods to characterize not only DCs but also other immune cells in steady state and atherosclerotic aorta...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28054922/evaluating-the-use-of-hematological-parameters-in-staging-hidradenitis-suppurativa
#7
Necdet Fatih Yaşar, Mustafa Ufuk Uylas, Mustafa Baspinar, Hakan Sarsilmaz, Ersin Ates, Serdar Erkasap, Adnan Sahin
INTRODUCTION: Recently, it has been shown that hematological parameters may be used as markers of inflammatory response. In this study, the authors aimed to identify the potential roles of the neutrophil-lymphocyte ratio (NLR) and other hematological markers in the evaluation of hidradenitis suppurativa (HS), a chronic, recurrent inflammatory disease. MATERIALS AND METHODS: A total of 35 patients, diagnosed with HS between January 1, 2012 and December 31, 2014, were categorized into 3 groups according to the Hurley staging system...
December 29, 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28051909/in-vitro-heterogeneous-degradation-of-alginate-and-its-validation-of-different-molecular-weight-on-blood-bio-compatibility
#8
Mengxue Xu, Chao Feng, Juan Wang, Xuqian Lang, Guixue Xia, Xiaoping Yu, Qiuxia Ji, Xiaojie Cheng, Ming Kong, Ya Liu, Xiguang Chen
In the present work, sodium alginate (ALG) was degraded by heterogeneous phase acid degradation. The molecular weight distribution of ALG after degradation was close to homogenization. Then the blood bio-compatibility of ALG with different molecular weights (ALG-0h 50,075, ALG-0.5h 20,680, ALG-2h 13,170 and ALG-96h 1170 kDa) was evaluated in vitro and vivo. The human umbilical vein endothelial cells were used to assess the cytotoxicity of ALGs, ALG-0.5h and ALG-2h exhibited greater increment in percentage of cell viability comparing with ALG-0h and ALG-96h...
January 18, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28044355/a-cellular-model-of-shear-induced-hemolysis
#9
Salman Sohrabi, Yaling Liu
A novel model is presented to study red blood cell (RBC) hemolysis at cellular level. Under high shear rates, pores form on RBC membranes through which hemoglobin (Hb) leaks out and increases free Hb content of plasma leading to hemolysis. By coupling lattice Boltzmann and spring connected network models through immersed boundary method, we estimate hemolysis of a single RBC under various shear rates. First, we use adaptive meshing to find local strain distribution and critical sites on RBC membranes, and then we apply underlying molecular dynamics simulations to evaluate damage...
January 3, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28006888/iron-parameters-prohepcidin-and-soluble-transferrin-receptor-levels-in-obese-children
#10
Güzide Doğan, Nesibe Andiran, Nurullah Çelik, Sema Uysal
BACKGROUND: Iron deficiency is common in obese children although the underlying mechanism is unclear. Several studies have investigated the relation between iron deficiency and obesity, but studies focusing on children are rare. The aim was to investigate the associations between iron parameters, prohepcidin and soluble transferrin receptor levels in obese children. METHODS: A total of 110 children, ranging in age from 6-16, 50 with primary obesity and 60 healthy children and adolescents, were enrolled...
December 22, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/28002028/within-day-biological-variation-and-hour-to-hour-reference-change-values-for-hematological-parameters
#11
Judith M Hilderink, Lieke J J Klinkenberg, Kristin M Aakre, Norbert C J de Wit, Yvonne M C Henskens, Noreen van der Linden, Otto Bekers, Roger J M W Rennenberg, Richard P Koopmans, Steven J R Meex
BACKGROUND: Middle- and long-term biological variation data for hematological parameters have been reported in the literature. Within-day 24-h variability profiles for hematological parameters are currently lacking. However, comprehensive hour-to-hour variability data are critical to detect diurnal cyclical rhythms, and to take into account the 'time of sample collection' as a possible determinant of natural fluctuation. In this study, we assessed 24-h variation profiles for 20 hematological parameters...
December 21, 2016: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/27994379/preoperative-red-cell-distribution-width-not-a-useful-prognostic-indicator-for-30-day-mortality-in-patients-who-undergo-major-or-ultra-major-noncardiac-surgery
#12
Yik-Nang Cheung, Hoi-Ping Shum, King-Chung Chan, Wing-Wa Yan
BACKGROUND: Red cell distribution width (RDW) has been shown to be associated with mortality in cardiac surgical patients. This study investigates the association of RDW with the 30-day mortality for those patients who undergo major- or ultra-major noncardiac surgery. METHODS: Patients who received major- or ultra-major noncardiac surgery between July 2012 and May 2013 were included in the study and patients those with preoperative hemoglobin <10 g/day were excluded from the study...
November 2016: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27993597/a-comparison-of-blood-nitric-oxide-metabolites-and-hemoglobin-functional-properties-among-diving-mammals
#13
Angela Fago, Daniel Garcia Parraga, Elin E Petersen, Niels Kristensen, Lea Giouri, Frank B Jensen
The ability of marine mammals to hunt prey at depth is known to rely on enhanced oxygen stores and on selective distribution of blood flow, but the molecular mechanisms regulating blood flow and oxygen transport remain unresolved. To investigate the molecular mechanisms that may be important in regulating blood flow, we measured concentration of nitrite and S-nitrosothiols (SNO), two metabolites of the vasodilator nitric oxide (NO), in the blood of 5 species of marine mammals differing in their dive duration: bottlenose dolphin, South American sea lion, harbor seal, walrus and beluga whale...
December 18, 2016: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/27957678/haemato-biochemical-non-specific-immunity-antioxidant-capacity-and-histopathological-changes-in-labeo-rohita-fingerlings-fed-rubber-protein-isolate
#14
Femi John Fawole, N P Sahu, K K Jain, S Gupta, K V Rajendran, N Shamna, Nalini Poojary
A 60-day feeding trial was conducted to evaluate the haemato-biochemical, innate immune response, antioxidant capacity and histopathological changes in Labeo rohita fingerlings fed rubber protein isolates (RPI). One hundred and eighty fingerlings (average weight 4.45 ± 0.01 g) were distributed into five experimental groups in triplicate and fed with isonitrogenous and isocaloric diets. Soybean protein isolate (SPI) served as the reference diet (Control), and the treatment diets were formulated as RPI25, RPI50, RPI75 and RPI100 replacing 25, 50, 75 and 100% of SPI protein, respectively...
December 12, 2016: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/27955893/distribution-of-local-anesthetics-between-aqueous-and-liposome-phases
#15
Suvi-Katriina Ruokonen, Filip Duša, Antti H Rantamäki, Alexandra Robciuc, Paula Holma, Juha M Holopainen, Mohamed Abdel-Rehim, Susanne K Wiedmer
Liposomes were used as biomimetic models in capillary electrokinetic chromatography (EKC) for the determination of distribution constants (KD) of certain local anesthetics and a commonly used preservative. Synthetic liposomes comprised phosphatidylcholine and phosphatidylglycerol phospholipids with and without cholesterol. In addition, ghost liposomes made from red blood cell (RBC) lipid extracts were used as pseudostationary phase to acquire information on how the liposome composition affects the interactions between anesthetics and liposomes...
January 6, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27939469/red-blood-cell-distribution-width-a-simple-parameter-in-preeclampsia
#16
Zehra Vural Yılmaz, Elif Yılmaz, Tuncay Küçüközkan
OBJECTIVE: Preeclampsia is a serious disease and a leading cause of maternal and perinatal mortality and morbidity. Red blood cell distribution width (RDW), a measure of anisocytosis, is used as an inflammation marker in hypertension and cardiovascular diseases. Although the relationship between RDW and hypertension has been well documented, the association between preeclampsia and RDW is not clear. We aimed to investigate the relationship between RDW and preeclampsia and its severity...
October 2016: Pregnancy Hypertension
https://www.readbyqxmd.com/read/27936006/prognostic-value-of-red-blood-cell-distribution-width-in-non-cardiovascular-critically-or-acutely-patients-a-systematic-review
#17
Rubin Luo, Jian Hu, Libing Jiang, Mao Zhang
BACKGROUND: RDW (red cell distribution width) has been reported to been associated with the prognosis of patients with cardiovascular diseases. However, RDW is often overlooked by clinicians in treating patients with non-cardiovascular diseases, especially in an emergency. The objective of this systematic review is to explore the prognostic value of RDW in non-cardiovascular emergencies. METHODS: PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were systematically searched from their inception to December 31, 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27932670/annals-express-red-blood-cell-distribution-width-and-neutrophil-to-lymphocyte-ratio-are-associated-with-outcomes-of-adult-subarachnoid-hemorrhage-patients-admitted-to-intensive-care-unit
#18
Yuan-Lan Huang, Zhi-Jun Han, Zhi-De Hu
BACKGROUND: Red blood cell distribution width (RDW) and neutrophil to lymphocyte ratio (NLR) have been reported to be associated with outcomes of acute cerebral infarction. However, their prognostic value in patients with subarachnoid hemorrhage (SAH) remains largely unknown. The aim of this study was to investigate the prognostic value of RDW and NLR in SAH patients. METHODS: Medical records of adult SAH patients admitted to intensive care unit (ICU) were extracted from Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II, version 2...
December 8, 2016: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/27926498/prognostic-value-of-rdw-in-cancers-a-systematic-review-and-meta-analysis
#19
REVIEW
Linhui Hu, Manman Li, Yangyang Ding, Lianfang Pu, Jun Liu, Jingxin Xie, Michael Cabanero, Jingrong Li, Ru Xiang, Shudao Xiong
Red blood cell distribution width (RDW), a parameter that used to differentiate the type of anemia for several decades, recent studies suggest it was a prognostic factor in various types of cancer patients. However, the prognostic value of RDW in cancer patients remains controversial. Here, we performed a meta-analysis and systematic review to evaluate the prognostic value of RDW in cancer patients. Relevant studies were picked out from the databases of Web of Science, Embase, Pubmed and Cochrane Library. A total of 16 papers with 4267 patients were included in this meta-analysis, and the combined results indicated that elevated RDW was associated with poor over survival (OS) (HR = 1...
December 2, 2016: Oncotarget
https://www.readbyqxmd.com/read/27925452/usefulness-of-admission-red-blood-cell-distribution-width-as-a-predictor-of-severity-of-acute-pulmonary-embolism
#20
Recep Akgedik, Harun Karamanli, Ali Bekir Kurt, Zeki Yüksel Günaydın
BACKGROUND: Previous researches have represented a considerable relation between acute pulmonary embolism (PE) and red blood cell distribution width (RDW). To the authors' knowledge no research has been informed in subjects with PE severity. Pulmonary arterial obstruction index (PAOI) is associated with the severity of acute PE. OBJECTIVES: In our investigation, we purposed to assess the relation between PAOI and RDW and the benefit of these factors in the detection of PE severity...
December 7, 2016: Clinical Respiratory Journal
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