keyword
MENU ▼
Read by QxMD icon Read
search

red blood cell distribution

keyword
https://www.readbyqxmd.com/read/29133071/red-blood-cell-distribution-width-is-associated-with-mortality-in-elderly-patients-with-sepsis
#1
An-Yi Wang, Hon-Ping Ma, Wei-Fong Kao, Shin-Han Tsai, Cheng-Kuei Chang
INTRODUCTION: RDW is a prognostic biomarker and associated with mortality in cardiovascular disease, stroke and metabolic syndrome. For elderly patients, malnutrition and multiple comorbidities exist, which could affect the discrimination ability of RDW in sepsis. The main purpose of our study was to evaluate the prognostic value of RDW in sepsis among elderly patients. METHODS: This was a retrospective cohort study conducted in emergency department intensive care units (ED-ICU) between April 2015 and November 2015...
November 10, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29125137/red-blood-cell-distribution-width-relative-lymphocyte-count-and-type-2-diabetes-mellitus-predict-all-cause-mortality-in-patients-with-advanced-heart-failure
#2
Bożena Szyguła-Jurkiewicz, Łukasz Siedlecki, Łukasz Pyka, Ewa Romuk, Piotr Przybyłowski, Mariusz Gąsior
INTRODUCTION    Early identification of patients with advanced heart failure (HF) who are at a higher risk for poor outcome is an important element of patient management, both from the medical and the economic point of view. OBJECTIVES    In the present study, we sought to determine the association between hematologic parameters assessed on admission and within the 3-year mortality period in patients consecutively admitted with advanced HF.  We also investigated the association between baseline demographic and clinical data and mortality...
November 9, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29120816/tumor-targeted-stealthy-and-degradable-bismuth-nanoparticles-for-enhanced-x-ray-radiation-therapy-of-breast-cancer
#3
Junjie Deng, Shandong Xu, Weike Hu, Xiaojie Xun, Liyuan Zheng, Ming Su
Nanoparticles of heavy elements can be used as radiosensitizers to enhance X-ray radiation therapy, but a major roadblock in translating nanoparticle radiosensitizers into clinical practice of cancer treatment is related to the non-degradable nature of the nanoparticles, which can cause accumulation inside body and long-term toxicity. This paper reports the use of a folate-inserted, red blood cell membrane-modified bismuth (i.e., F-RBC bismuth) nanoparticles in X-ray radiation therapy for breast cancer, where cell membrane coating provides long blood circulation time, folate acts as tumor targeting agent, X-ray and bismuth nanoparticles interaction generates more free radicals for cancer cells damage, and physiological condition helps dissolve bismuth nanoparticles after treatment...
October 30, 2017: Biomaterials
https://www.readbyqxmd.com/read/29114616/detection-of-regional-radiation-induced-lung-injury-using-hyperpolarized-129-xe-chemical-shift-imaging-in-a-rat-model-involving-partial-lung-irradiation-proof-of-concept-demonstration
#4
Brandon Zanette, Elaine Stirrat, Salomeh Jelveh, Andrew Hope, Giles Santyr
Purpose: The purpose of this work was to use magnetic resonance imaging (MRI) of hyperpolarized (HP) (129)Xe dissolved in pulmonary tissue (PT) and red blood cells (RBCs) to detect regional changes to PT structure and perfusion in a partial-lung rat model of radiation-induced lung injury and compare with histology. Methods and materials: The right medial region of the lungs of 6 Sprague-Dawley rats was irradiated (20 Gy, single-fraction). A second nonirradiated cohort served as the control group...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114229/structural-control-of-microvessel-diameters-origins-of-metabolic-signals
#5
Bettina Reglin, Timothy W Secomb, Axel R Pries
Diameters of microvessels undergo continuous structural adaptation in response to hemodynamic and metabolic stimuli. To ensure adequate flow distribution, metabolic responses are needed to increase diameters of vessels feeding poorly perfused regions. Possible modes of metabolic control include release of signaling substances from vessel walls, from the supplied tissue and from red blood cells (RBC). Here, a theoretical model was used to compare the abilities of these metabolic control modes to provide adequate tissue oxygenation, and to generate blood flow velocities in agreement with experimental observations...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29109595/the-role-of-hematological-indices-in-patients-with-acute-coronary-syndrome
#6
REVIEW
Jan Budzianowski, Konrad Pieszko, Paweł Burchardt, Janusz Rzeźniczak, Jarosław Hiczkiewicz
An increased systemic and local inflammation plays a key role in the pathophysiology of acute coronary syndrome (ACS). This review will discuss the role of hematological indices: white blood cells (WBC), neutrophil to lymphocyte ratio (NLR), red cell distribution width (RDW), and platelet indices, that is, platelet to lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet distribution width (PDW) in the case of ACS. In recent years, a strong interest has been drawn to these indices, given that they may provide independent information on pathophysiology, risk stratification, and optimal management...
2017: Disease Markers
https://www.readbyqxmd.com/read/29107511/red-blood-cells-distribution-width-as-a-potential-prognostic-biomarker-in-patients-with-pulmonary-arterial-hypertension-and-chronic-thromboembolic-pulmonary-hypertension
#7
Anna Smukowska-Gorynia, Iga Tomaszewska, Katarzyna Malaczynska-Rajpold, Justyna Marcinkowska, Anna Komosa, Magdalena Janus, Anna Olasinska-Wisniewska, Sylwia Slawek, Aleksander Araszkiewicz, Stanislaw Jankiewicz, Tatiana Mularek-Kubzdela
BACKGROUND: Red blood cells distribution width (RDW) predicts survival in cardiovascular diseases. Little is known about the variability of RDW level over time among patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). To our knowledge, RDW has never been analysed as a marker of response to specific treatment. MATERIALS AND METHODS: We retrospectively analysed 77 patients for: i) RDW measured during the last hospitalisation before death or during the last follow-up (RDWlast); ii) mean RDW from all hospitalisations during the entire follow-up of the patient (RDWmean); iii) maximum RDW of all hospitalisations of each patient (RDWmax)...
August 24, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29101675/red-blood-cell-distribution-width-a-potential-laboratory-parameter-for-monitoring-inflammation-in-rheumatoid-arthritis
#8
Yujue He, Can Liu, Zhiyong Zeng, Weilin Ye, Jinpiao Lin, Qishui Ou
Correlation analysis of red blood cell distribution width (RDW) and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), tumor necrosis factor α (TNF-α), interleukin (IL)-6, and IL-10 in rheumatoid arthritis (RA) to investigate whether RDW can serve as a potential parameter for indicating inflammation in RA patients. A total of 670 RA patients from October 2014 to April 2016 were enrolled in our study. The white blood cell (WBC), red blood cell (RBC), platelet (PLT), hemoglobin (HGB), RDW, CRP, and ESR in peripheral blood of patients with RA were retrospectively analyzed...
November 3, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29096100/layered-double-hydroxide-nanoparticles-impact-on-vascular-cells-blood-cells-and-the-complement-system
#9
Zi Gu, Shiyu Yan, Soshan Cheong, Zhenbang Cao, Huali Zuo, Anita C Thomas, Barbara E Rolfe, Zhi Ping Xu
The mounting interest in layered double hydroxide (LDH) nanoparticles as drug carriers and bio-imaging contrast agents makes biosafety evaluation of LDH essential. Considering the important role of blood circulation in bio-distribution of nanoparticles, the present work evaluated the impact of MgAl-LDHs on key components of the circulatory system, including vascular cells (vascular smooth muscle cells (SMCs) and endothelial cells (HUVECs)), red blood cells (RBCs), and complement activation. The results showed that LDH had no effects on SMCs and HUVECs at concentrations up to 500 and 10 µg/mL respectively, in terms of cell proliferation and viability...
October 19, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29092215/reconstructions-of-refractive-index-tomograms-via-a-discrete-algebraic-reconstruction-technique
#10
Moosung Lee, Seungwoo Shin, Yongkeun Park
Optical diffraction tomography (ODT) provides three-dimensional refractive index (RI) tomograms of a transparent microscopic object. However, because of the finite numerical aperture of objective lenses, ODT has a limited access to diffracted light and suffers from poor spatial resolution, particularly along the axial direction. To overcome the limitation of the quality of RI tomography, we present an algorithm that accurately reconstructs RI tomography of a specimen with discrete and uniform RI, using prior information about the RI levels...
October 30, 2017: Optics Express
https://www.readbyqxmd.com/read/29090247/perioperative-red-blood-cell-transfusion-in-orofacial-surgery
#11
REVIEW
So-Young Park, Kwang-Suk Seo, Myong-Hwan Karm
In the field of orofacial surgery, a red blood cell transfusion (RBCT) is occasionally required during double jaw and oral cancer surgery. However, the question remains whether the effect of RBCT during the perioperative period is beneficial or harmful. The answer to this question remains challenging. In the field of orofacial surgery, transfusion is performed for the purpose of oxygen transfer to hypoxic tissues and plasma volume expansion when there is bleeding. However, there are various risks, such as infectious complications (viral and bacterial), transfusion-related acute lung injury, ABO and non-ABO associated hemolytic transfusion reactions, febrile non-hemolytic transfusion reactions, transfusion associated graft-versus-host disease, transfusion associated circulatory overload, and hypersensitivity transfusion reaction including anaphylaxis and transfusion-related immune-modulation...
September 2017: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/29084189/-multiorgan-malfunction-after-fontan-operation-in-adult-patients
#12
Monika Smaś-Suska, Paweł Iwaszczuk, Beata Róg, Piotr Weryński, Maria Olszowska, Piotr Podolec, Lidia Tomkiewicz-Pająk
Although 85% of patients with univentricular heart after Fontan procedure survive twenty years after operation, the procedure alone seems to be an inadequate treatment as a permanent clinical solution. Patients with a "Fontan physiology" additionally have to face a various extra-cardiac complications, including thyroid, liver and kidney dysfunction, which are not only potentially life-threatening, but also can potentiate the circulatory insufficiency. AIM: The aim of the study was to assess a multiorgan dysfunction in adult patients after Fontan operation in long term follow-up and compare to healthy controls...
October 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29072032/training-induced-annual-changes-in-red-blood-cell-profile-in-highly-trained-endurance-and-speed-power-athletes
#13
Monika Ciekot-Sołtysiak, Krzysztof Kusy, Tomasz Podgórski, Jacek Zieliński
BACKGROUND: An extensive body of literature exists on the effects of training on haematological parameters, but the previous studies have not reported how hematological parameters respond to changes in training loads within consecutive phases of the training cycle in highly-trained athletes in extremely different sport disciplines. The aim of this study was to identify changes in red blood cell (RBC) profile in response to training loads in consecutive phases of the annual training cycle in highly-trained sprinters (8 men, aged 24 ± 3 years) and triathletes (6 men, aged 24 ± 4 years) who competed at the national and international level...
October 24, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29071816/application-of-multiplex-ligation-dependent-probe-amplification-assay-for-genotyping-major-blood-group-systems-including-del-variants-in-the-d-negative-korean-population
#14
Banseok Kim, Seung Tae Lee, Sinyoung Kim, Jong Rak Choi, Hyun Ok Kim
BACKGROUND: The DEL blood type, a very weak D variant, is a major concern in the field of transfusion medicine because of its potential to cause anti-D alloimmunization. We investigated the molecular basis of serologically D-negative phenotypes, including the DEL type, and the distribution of other blood group systems in the Korean population using the recently developed multiplex ligation-dependent probe amplification (MLPA) assay. METHODS: Blood group genotyping using the MLPA assay and RhCE phenotyping were performed on randomly selected 95 D-negative red blood cell products...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29069071/clinical-signi%C3%AF-cance-of-routine-blood-test-associated-inflammatory-index-in-breast-cancer-patients
#15
Hong Sun, Chang-Qing Yin, Qing Liu, Fubing Wang, Chun-Hui Yuan
BACKGROUND It is now widely acknowledged that chronic inflammation is closely associated with the process of cancer development. As a simple noninvasive blood-based test, hematological parameters in the routine blood test have been considered as inflammation markers. We aimed to evaluate platelet count (PC), red blood cell distribution width (RDW), white blood cell count (WBC), mean platelet volume (MPV), number of neutrophils/lymphocytes ratio (NLR), and platelet count/lymphocytes ratio (PLR) as surrogate inflammatory markers in breast cancer (BC) patients, and we compared these to those in healthy individuals...
October 25, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29067069/can-hematologic-parameters-predict-treatment-of-ectopic-pregnancy
#16
Hatice Akkaya, Gulsum Uysal
OBJECTIVE: Ectopic pregnancy (EP) is the major cause of maternal morbidity and mortalityinthe first trimester of pregnancy. EP can be treated either medical or surgical approches. The purpose of our study wasto predict the treatment choice of tubal EP by usinghematologic parameters which are routinely used in clinical practice. METHODS: After retrospectively data evaluation was done from Januaryu 2014 to Deceber 201. we had 153 patients with EP. Patientsadmitted to methotrexate (MTX) therapy was Group-1...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29064853/red-blood-cell-distribution-width-independently-predicts-1-month-mortality-in-acute-decompensation-of-cirrhotic-patients-admitted-to-emergency-department
#17
Gianni Turcato, Tommaso Campagnaro, Antonio Bonora, Nicola Vignola, Gian Luca Salvagno, Gianfranco Cervellin, Giorgio Ricci, Antonio Maccagnani, Giuseppe Lippi
AIM: The aim of this study was to explore whether red blood cell distribution width (RDW) can help predict the risk of short-term mortality in patients with acute decompensation of cirrhosis. PATIENTS AND METHODS: We carried out a retrospective analysis of all patients consecutively admitted to the emergency department (ED) of the University Hospital of Verona (Italy) for acute decompensation of liver cirrhosis, between 1 June 2013 and 31 December 2016. The RDW value was measured at ED admission, along with collection of clinical features and other laboratory data, and was then correlated with severity of disease (Chronic Liver Failure Consortium Acute Decompensation score; CLIF-C AD score) and 1-month mortality...
October 23, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29063631/donor-specific-individuality-of-red-blood-cell-performance-during-storage-is-partly-a-function-of-serum-uric-acid-levels
#18
Vassilis L Tzounakas, Dimitrios G Karadimas, Alkmini T Anastasiadi, Hara T Georgatzakou, Eleftheria Kazepidou, Dimitris Moschovas, Athanassios D Velentzas, Anastasios G Kriebardis, Nikolaos E Zafeiropoulos, Apostolos Avgeropoulos, Marilena Lekka, Konstantinos E Stamoulis, Issidora S Papassideri, Marianna H Antonelou
BACKGROUND: Previous investigations in leukoreduced units of red blood cells (RBCs) in mannitol additive solution revealed the close association of uric acid (UA) levels in vivo with the susceptibility of RBCs to storage lesion markers. In this study, we examined whether UA has a similar correlation with the capability of RBCs to cope with the oxidative provocations of storage under different conditions, namely, in CPDA-1 and in the absence of leukoreduction. STUDY DESIGN AND METHODS: The UA-dependent antioxidant capacity of the supernatant was measured in nonleukoreduced units of RBCs in CPDA (n = 47)...
October 23, 2017: Transfusion
https://www.readbyqxmd.com/read/29060914/three-wavelength-method-for-the-optical-differentiation-of-methemoglobin-and-sulfhemoglobin-in-oxygenated-blood
#19
Spencer R Van Leeuwen, Gladimir V G Baranoski, Bradley W Kimmel
Methemoglobinemia and sulfhemoglobinemia are rare, but potentially life threatening, diseases that refer to an abnormal amount of methemoglobin or sulfhemoglobin in the blood, respectively. Unfortunately, blood samples containing abnormal quantities of methemoglobin or sulfhemoglobin have similar spectral characteristics. This makes it difficult to optically differentiate them and, hence, difficult to diagnose a patient with either disease. However, performing treatments for one of the diseases without a correct diagnosis can introduce increased risk to the patient...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060461/in-silico-investigation-of-the-effects-of-hemolysis-on-the-hyperspectral-absorptance-of-blood-in-motion
#20
Spencer R Van Leeuwen, Gladimir V G Baranoski, Bradley W Kimmel
Measurement of the optical absorptance of blood can provide insight into its composition and behaviour. Accordingly, optical devices and sensors are commonly used in a clinical setting to measure the absorptance of blood, either directly or indirectly through measurement of skin spectral responses. These measurements enable the evaluation or constant monitoring of a patient's blood. In this paper, we perform predictive simulations to investigate the absorptance of blood and how it is affected by hemolysis. These simulations are performed using a cell-based light interaction model, known as CLBlood, which accounts for the orientation and distribution of red blood cells...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
keyword
keyword
59402
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"