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https://www.readbyqxmd.com/read/29452385/longitudinal-tobacco-use-transitions-among-adolescents-and-young-adults-2014-2016
#1
Elizabeth C Hair, Alexa R Romberg, Raymond Niaura, David B Abrams, Morgane A Bennett, Haijun Xiao, Jessica M Rath, Lindsay Pitzer, Donna Vallone
Introduction: Among youth, the frequency and prevalence of using more than one tobacco (small cigar, cigarette, and hookah) or nicotine-containing product (e-cigarettes-ENDS) are changing. These shifts pose challenges for regulation, intervention, and prevention campaigns because of scant longitudinal data on the stability of use patterns in this changing product landscape. Methods: A nationally representative longitudinal survey of 15- to 21-year olds (n = 15,275) was used to describe transitions between never use, noncurrent use, and past 30-day use of combustible tobacco, e-cigarettes (ENDS), and dual use of both kinds of products...
February 13, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29451226/final-adult-height-and-endocrine-complications-in-young-adults-with-%C3%AE-thalassemia-major-tm-who-received-oral-iron-chelation-oic-in-comparison-with-those-who-did-not-use-oic
#2
Ashraf T Soliman, Mohamed A Yassin, Vincenzo De Sanctis
BACKGROUND: Relatively little is known about endocrine function, bone mineral health, and growth during oral iron chelation therapy in β-thalassemia major patients (TM) on treatment with deferasirox. AIMS OF THE STUDY: To study the frequency of endocrine complications, IGF-1 levels and final adult standing height (FA-Ht) in patients with BTM in two groups of adult patients. PATIENTS AND METHODS: The first group (Group A; 15 patients, 6 females and 9 males) received oral iron chelation therapy (OIC) with deferasirox for 6 years before puberty; the second group (Group B;40 patients) attained the FA-Ht before the use of OIC (iron chelation therapy with deferoxamine (DFO) given subcutaneously, since the age of 2 years)...
February 16, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29450662/preconception-counseling-for-adolescents-and-young-adults-with-diabetes-a-literature-review-of-the-past-10-years
#3
REVIEW
Frances Peterson-Burch, Hiba Abujaradeh, Nicole Charache, Andrea Fischl, Denise Charron-Prochownik
PURPOSE OF REVIEW: Women with diabetes who have unplanned pregnancies and uncontrolled blood sugars are at a higher risk for maternal and fetal morbidities and mortalities. Preconception counseling (PC) has been shown to decrease the risks and improve health outcomes. From 2009 to 2017, the American Diabetes Association has recommended that preconception counseling be given at each clinic visit for all women with diabetes of childbearing age starting at puberty (prior to sexual debut)...
February 15, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29450465/pediatric-inspired-treatment-regimens-for-adolescents-and-young-adults-with-philadelphia-chromosome-negative-acute-lymphoblastic-leukemia-a-review
#4
Stuart E Siegel, Wendy Stock, Rebecca H Johnson, Anjali Advani, Lori Muffly, Dan Douer, Damon Reed, Mark Lewis, David R Freyer, Bijal Shah, Selina Luger, Brandon Hayes-Lattin, Jerry J Jaboin, Peter F Coccia, Daniel J DeAngelo, Nita Seibel, Archie Bleyer
Importance: The incidence of acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in adolescent and young adult (AYA) patients (age range, 15-39 years) in the United States is increasing at a greater rate than in younger or older persons. Their optimal treatment has been increasingly debated as pediatric regimens have become more widely used in the age group. This review compares the basic features of pediatric and adult chemotherapy regimens for ALL and LBL, recognizes and describes the challenges of the pediatric regimen, and suggests strategies to facilitate its adoption for AYAs with ALL and LBL...
February 15, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29449513/adolescents-and-young-adults-with-a-rare-cancer-getting-past-semantics-to-optimal-care-for-patients-with-germ-cell-tumors
#5
Sara J Stoneham, Juliet P Hale, Carlos Rodriguez-Galindo, Ha Dang, Thomas Olson, Matthew Murray, James F Amatruda, Claire Thornton, G Suren Arul, Deborah Billmire, Mark Krailo, Dan Stark, Al Covens, Jean Hurteau, Sally Stenning, James C Nicholson, David Gershenson, A Lindsay Frazier
No abstract text is available yet for this article.
February 2018: Oncologist
https://www.readbyqxmd.com/read/29447146/health-risk-behaviors-and-chronic-conditions-among-adults-with-inflammatory-bowel-disease-united-states-2015-and-2016
#6
Fang Xu, James M Dahlhamer, Emily P Zammitti, Anne G Wheaton, Janet B Croft
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, involves chronic inflammation of the gastrointestinal tract. In 2015, an estimated 3.1 million adults in the United States had ever received a diagnosis of IBD (1). Nationally representative samples of adults with IBD have been unavailable or too small to assess relationships between IBD and other chronic conditions and health-risk behaviors (2). To assess the prevalence of health-risk behaviors and chronic conditions among adults with and without IBD, CDC aggregated survey data from the 2015 and 2016 National Health Interview Survey (NHIS)...
February 16, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29446833/body-fat-content-fat-distribution-and-adipocytokine-production-and-their-correlation-with-fertility-markers-in-young-adult-men-and-women-conceived-by-icsi
#7
F Belva, J De Schepper, M Roelants, H Tournaye, M Bonduelle, S Provyn
OBJECTIVE: Differences in body fat content during childhood and adolescence have been described in offspring conceived by In Vitro Fertilisation (IVF) and Intracytoplasmic Sperm Injection (ICSI). However, data on body fat and its distribution as well as on adipocytokine production in young adults conceived by ICSI are non-existent. We investigated if young adult men and women conceived by ICSI have a normal body fat patterning and adipocytokine production. DESIGN: Cohort study...
February 15, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29446217/clinical-staging-model-in-offspring-of-parents-with-bipolar-disorder-a-systematic-review
#8
REVIEW
Aigli Raouna, Cemre Su Osam, Angus MacBeth
OBJECTIVE: We sought to systematically review the literature on the psychiatric risk of offspring of parents with bipolar disorder (OPBD) using a developmental psychopathology framework. The review also sought to establish the utility of clinical stage modelling as a framework for identifying precursor disorders to later onset of bipolar disorder (BD) in OPBD. METHODS: A systematic search was performed using EMBASE, PsychINFO and Medline. Reference lists of included studies and previous reviews were also searched...
February 15, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29444895/optimizing-hybrid-closed-loop-therapy-in-adolescents-and-emerging-adults-using-the-minimed-670g-system
#9
Laurel H Messer, Gregory P Forlenza, Jennifer L Sherr, R Paul Wadwa, Bruce A Buckingham, Stuart A Weinzimer, David M Maahs, Robert H Slover
OBJECTIVE: The MiniMed 670G System is the first commercial hybrid closed-loop (HCL) system for management of type 1 diabetes. Using data from adolescent and young adult participants, we compared insulin delivery patterns and time-in-range metrics in HCL (Auto Mode) and open-loop (OL). System alerts, usage profiles, and operational parameters were examined to provide suggestions for optimal clinical use of the system. RESEARCH DESIGN AND METHODS: Data from 31 adolescent and young adult participants (14-26 years old) at three clinical sites in the 670G pivotal trial were analyzed...
February 14, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29444185/humoral-and-cell-mediated-immune-responses-after-a-booster-dose-of-hbv-vaccine-in-hiv-infected-children-adolescents-and-young-adults
#10
Vania Giacomet, Michela Masetti, Pilar Nannini, Federica Forlanini, Mario Clerici, Gian Vincenzo Zuccotti, Daria Trabattoni
OBJECTIVE: HBV vaccine induces protective antibodies only in 23-56% of HIV-infected children. The aim of our study is to evaluate the immunologic effects of a booster dose of HBV vaccine in HIV-infected youth. DESIGN: 53 young HIV-infected patients in whom HBV vaccination did not elicit protective Ab titers were enrolled. All patients were on ART with optimal immunological and viral response. METHOD: All patients received a booster dose of HBV vaccine (HBVAXPRO 10 μg i...
2018: PloS One
https://www.readbyqxmd.com/read/29442287/recent-developments-in-adolescent-and-young-adult-aya-acute-lymphoblastic-leukemia
#11
REVIEW
Victor M Orellana-Noia, Michael G Douvas
PURPOSE OF REVIEW: Adolescent and Young Adult (AYA) Oncology is a relatively new field encompassing research in the unique pathophysiology, clinical care, and psychosocial issues facing patients between the ages of 15 and 40 with cancer. About 100,000 of the approximately 1.5 million people diagnosed annually with cancer in the USA are in this age range. This chapter will review notable new developments in the care of adolescents and young adults with acute lymphoblastic leukemia (ALL) within the last 3 years...
February 14, 2018: Current Hematologic Malignancy Reports
https://www.readbyqxmd.com/read/29441653/cognitive-control-under-stressful-conditions-in-transitional-age-youth-with-bipolar-disorder-diagnostic-and-sleep-related-differences-in-fronto-limbic-activation-patterns
#12
Adriane M Soehner, Tina R Goldstein, Sarah M Gratzmiller, Mary L Phillips, Peter L Franzen
OBJECTIVES: Adults with bipolar disorder (BD) display aberrant activation in fronto-limbic neural circuitry during cognitive control. However, fronto-limbic response to cognitive control, and factors destabilizing this circuitry, remain under-studied during the transition from adolescence to young adulthood in BD. Sleep patterns are disturbed in BD, undergo change in adolescence, and support brain function. Among transitional age youth, BD diagnosis and sleep (duration and variability) were tested as predictors of fronto-limbic response to a stressful cognitive control task...
February 13, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29441182/pediatric-cardiac-anamnesis-prevention-of-additional-diagnostic-tests
#13
REVIEW
Izet Masic, Zijo Begic, Nabil Naser, Edin Begic
Pediatrics is defined as the science of a healthy and sick child from birth to end of adolescence. Diseases of the cardiovascular system are the leading causes of mortality in adults, with frequent onset in childhood. The cardiologic examination starts with anamnesis in a pleasant atmosphere, refined space, enough time and patience, detailed measurements, and preferably a noncrying child. Anamnesis, regardless of the development of diagnostic procedures, still constitutes the basis of every clinical examination...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29440857/eruptive-vellus-hair-cyst-an-uncommon-and-underdiagnosed-entity
#14
Priyanka Anand, Namrata Sarin, Rachita Misri, V K Khurana
Eruptive vellus hair cyst (EVHC) is a rare follicular developmental abnormality of the vellus hair follicles. They are usually seen in children, adolescents, or young adults and manifest as reddish-brown smooth papules most commonly involving the chest, limbs, and abdomen. An 18-year-old male presented with asymptomatic papules on the trunk and flexor aspect of both forearms for the past 2 years. There was no family history of similar lesions. His medical history was also not contributory. A clinical diagnosis of steatocystoma multiplex and chronic folliculitis was given, and a punch biopsy from the papule was performed and sent for histopathological examination...
January 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29440190/a-model-linking-sickle-cell-hemoglobinopathies-and-smarcb1-loss-in-renal-medullary-carcinoma
#15
Pavlos Msaouel, Nizar M Tannir, Cheryl Lyn Walker
Renal medullary carcinoma (RMC) is a highly aggressive malignancy that predominantly afflicts young adults and adolescents with sickle hemoglobinopathies. It is characterized by complete loss of expression of the chromatin remodeler and tumor suppressor SMARCB1. Despite therapy, the outcomes of patients with RMC remain very poor, highlighting the need to understand the etiology of this cancer, and develop new diagnostic, preventive, and therapeutic strategies. A key knowledge gap in RMC biology is why sickle hemoglobinopathies predispose to the development of this cancer...
February 12, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29439190/disparities-in-injury-morbidity-among-young-adults-in-the-usa-individual-and-contextual-determinants
#16
Susanne Schmidt, P Johnelle Sparks
BACKGROUND: Injuries have been recognised as important public health concerns, particularly among adolescents and young adults. Few studies have examined injuries using a multilevel perspective that addresses individual socioeconomic status (SES) and health behaviours and local socioeconomic conditions in early adolescence. We offer a conceptual framework incorporating these various components. METHODS: We test our conceptual framework using population data from the National Longitudinal Study of Adolescent Health Wave 4 when respondents were young adults and linked them to contextual level data from when they were middle-schoolers...
February 8, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29437492/the-experience-of-adolescents-and-young-adults-treated-for-cancer-in-an-adult-setting-a-review-of-the-literature
#17
Steve Marshall, Anne Grinyer, Mark Limmer
The purpose of this review is to explore the literature on the experience of adolescents and young adults (AYAs) having cancer treatment in an adult setting, rather than on a specialist adolescent cancer unit. The integrative review method was used to explore the current literature. Primary research on the topic was located systematically and then synthesized into a thematic narrative. The experience of AYAs undergoing treatment in an adult setting was generally negative. This can be attributed to three themes: feeling isolated in the adult setting; the lack of empathy from staff working in the adult setting; and the inappropriateness of the adult environment for this age group...
February 13, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29436455/sleep-in-adolescents-and-young-adults
#18
Martin Lee
No abstract text is available yet for this article.
February 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29435787/a-developmental-perspective-on-young-adult-romantic-relationships-examining-family-and-individual-factors-in-adolescence
#19
Mengya Xia, Gregory M Fosco, Melissa A Lippold, Mark E Feinberg
The ability to develop and maintain healthy romantic relationships is a key developmental task in young adulthood. The present study investigated how adolescent interpersonal skills (assertiveness, positive engagement) and family processes (family climate, parenting practices) influence the development of young adult romantic relationship functioning. We evaluated cross-lag structural equation models with a sample of 974 early adolescents living in rural and semi-rural communities in Pennsylvania and Iowa, starting in sixth grade (mean age = 12...
February 13, 2018: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/29435471/hiv-1-drug-resistance-and-third-line-therapy-outcomes-in-patients-failing-second-line-therapy-in-zimbabwe
#20
Cleophas Chimbetete, David Katzenstein, Tinei Shamu, Adrian Spoerri, Janne Estill, Matthias Egger, Olivia Keiser
Objectives: To analyze the patterns and risk factors of HIV drug resistance mutations among patients failing second-line treatment and to describe early treatment responses to recommended third-line antiretroviral therapy (ART) in a national referral HIV clinic in Zimbabwe. Methods: Patients on boosted protease inhibitor (PI) regimens for more than 6 months with treatment failure confirmed by 2 viral load (VL) tests >1000 copies/mL were genotyped, and susceptibility to available antiretroviral drugs was estimated by the Stanford HIVdb program...
February 2018: Open Forum Infectious Diseases
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