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Diabetes urinary anomalies

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https://www.readbyqxmd.com/read/27686059/a-randomised-controlled-trial-evaluating-renal-protective-effects-of-selenium-with-vitamins-a-c-e-verapamil-and-losartan-against-extracorporeal-shockwave-lithotripsy-induced-renal-injury
#1
Ahmed R El-Nahas, Mohamed M Elsaadany, Diaa-Eldin Taha, Ahmed M Elshal, Mohamed Abo El-Ghar, Amani M Ismail, Essam A Elsawy, Hazem H Saleh, Ehab W Wafa, Amira Awadalla, Tamer S Barakat, Khaled Z Sheir
OBJECTIVE: To evaluate the protective effects of selenium with vitamins A, C and E (selenium ACE, i.e. antioxidants), verapamil (calcium channel blocker), and losartan (angiotensin receptor blocker) against extracorporeal shockwave lithotripsy (ESWL)-induced renal injury. PATIENTS AND METHODS: A randomised controlled trial was conducted between August 2012 and February 2015. Inclusion criteria were adult patients with a single renal stone (<2 cm) suitable for ESWL...
September 30, 2016: BJU International
https://www.readbyqxmd.com/read/27040999/maternal-risk-factors-involved-in-specific-congenital-anomalies-of-the-kidney-and-urinary-tract-a-case-control-study
#2
Sander Groen In 't Woud, Kirsten Y Renkema, Michiel F Schreuder, Charlotte H W Wijers, Loes F M van der Zanden, Nine V A M Knoers, Wout F J Feitz, Ernie M H F Bongers, Nel Roeleveld, Iris A L M van Rooij
BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT) comprise a heterogeneous group of birth defects with a variety of genetic and nongenetic factors suspected of involvement in the etiology. However, little is known about risk factors in specific CAKUT phenotypes. Therefore, we studied potential maternal risk factors in individual phenotypes within the CAKUT spectrum. METHODS: Questionnaire data were collected from parents of 562 children with CAKUT and 2139 healthy controls within the AGORA data- and biobank...
July 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/26844492/incidence-and-risks-of-congenital-anomalies-of-kidney-and-urinary-tract-in-newborns-a-population-based-case-control-study-in-taiwan
#3
You-Lin Tain, Hsing Luh, Ching-Yuang Lin, Chien-Ning Hsu
Congenital anomalies of the kidney and urinary tract (CAKUT) are 1 of the major factors in young adults needing renal replacement therapy, but there is little extensive assessment of their incidence and risk factors. This study aimed to evaluate trends in the incidence of and risk factors for CAKUT among all births in Taiwan.This population-based case-control study design was conducted using the Taiwan national births registry, which contains detailed information about maternal health and characteristics of newborns, supplied by health professionals...
February 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26833755/congenital-anomalies-of-the-kidney-and-the-urinary-tract-a-murmansk-county-birth-registry-study
#4
Vitaly A Postoev, Andrej M Grjibovski, Anton A Kovalenko, Erik Eik Anda, Evert Nieboer, Jon Øyvind Odland
BACKGROUND: Congenital anomalies of the kidney and the urinary tract (CAKUTs) are relatively common birth defects. The combined prevalence in Europe was 3.3 per 1000 in 2012. The risk factors for these anomalies are not clearly identified. The aims of our study were to calculate the birth prevalences of urinary malformations in Murmansk County during 2006 to 2011 and to investigate related prenatal risk factors. METHODS: The Murmansk County Birth Registry was the primary source of information and our study included 50,936 singletons in the examination of structure, prevalence and proportional distribution of CAKUTs...
March 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/26673201/whole-egg-consumption-prevents-diminished-serum-25-hydroxycholecalciferol-concentrations-in-type-2-diabetic-rats
#5
Samantha K Jones, Gar Yee Koh, Matthew J Rowling, Kevin L Schalinske
Type 2 diabetes (T2D) is characterized by vitamin D deficiency owing to increased urinary loss of 25-hydroxycholecalciferol (25D). Whole eggs are a rich source of vitamin D, particularly 25D, the circulating form that reflects status. Zucker diabetic (type 2) fatty (ZDF) rats and their lean counterparts were fed casein- or whole egg-based diets for 8 weeks. Whole egg consumption attenuated both hyperglycemia and hypertriglyceridemia, as well as reduced weight gain in ZDF rats compared to casein-fed diabetic rats...
January 13, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/26428651/late-onset-secondary-nocturnal-enuresis-in-adolescents-associated-with-post-traumatic-stress-disorder-developed-after-a-traffic-accident
#6
Serkan Akan, Ahmet Ürkmez, Caglar Yildirim, Aytac Sahin, Özgür Haki Yüksel, Ayhan Verit
Secondary nocturnal enuresis is generally seen between 5 and 7 years of age and it is rarely encountered when compared with the primary incontinence. Patients with suggested diagnosis of secondary nocturnal enuresis should be examined for neurological and spinal anomalies and diabetes mellitus, diabetes insipidus, renal failure and urinary tract infection should be ruled out in differential diagnosis (1-3). Herein, we are presenting case reports of adolescent patients with secondary nocturnal enuresis refractory to medical therapy and developed after in-vehicle and extravehicular accidents...
September 30, 2015: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/25919497/diabetes-induced-congenital-anomalies-of-the-kidney-and-urinary-tract-cakut-nurture-and-nature-at-work
#7
EDITORIAL
Kirsten Y Renkema, Marianne C Verhaar, Nine V A M Knoers
No abstract text is available yet for this article.
May 2015: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/25595566/maternal-diabetes-mellitus-and-congenital-anomalies-of-the-kidney-and-urinary-tract-cakut-in-the-child
#8
Allison B Dart, Chelsea A Ruth, Elizabeth A Sellers, Wendy Au, Heather J Dean
BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT) are the primary cause of chronic kidney disease in children. The relevance of timing of diabetes mellitus (DM) exposure on risk of CAKUT in exposed children is unknown. STUDY DESIGN: Population-based nested case-control study. SETTING & PARTICIPANTS: Infants born between fiscal years 1996/1997 and 2009/2010 in Manitoba, Canada, identified using administrative data housed at the Manitoba Centre for Health Policy...
May 2015: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/24173305/-not-available
#9
B Gibb, R Giebelmann, S Martin, F Martin, M Schulz, H G Lippmann
The object of this study was that of getting additional insight into the mechanism of proteinuria through analysis of the permeability of the glomerular filter for higher molecular weight proteins in patients with proteinuria resulting from diabetic nephropathy. Fifty hospitalized patients with insulin-requiring diabetes mellitus were selected according to the presence of proteinuria and divided into two groups: group I, with or without only minor symptoms of diabetic angiopathy; group II, with moderate to severe diabetic nephropathy and retinopathy grades 1 to 3...
April 1966: Diabetologia
https://www.readbyqxmd.com/read/23908517/nephrogenic-diabetes-insipidus-partially-responsive-to-oral-desmopressin-in-a-subject-with-lithium-induced-multiple-endocrinopathy
#10
C Kamath, J Govindan, A D Premawardhana, S J Wood, M A Adlan, L D Premawardhana
Lithium (Li) may cause multiple endocrinopathies, including hypercalcaemia, thyroid dysfunction and nephrogenic diabetes insipidus (NDI), but rarely in the same patient. The management of NDI remains a challenge. We report on a patient on long-term Li who had simultaneous NDI (paired serum and urine samples had abnormal osmolalities, typical of NDI, and treatment with parenteral desmopressin failed to affect urinary volume and serum osmolality), 'destructive' thyroiditis (hyperthyroidism, absent radioiodine uptake and absent thyrotrophin receptor antibodies) and primary hyperparathyroidism (compatible biochemistry, urine calcium excluding 'set point' anomalies and hypocalciuric hypercalcaemia, and normal parathyroid imaging)...
August 2013: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/23727699/impact-of-prenatal-risk-factors-on-congenital-heart-disease-in-the-current-era
#11
Alan Fung, Cedric Manlhiot, Sapna Naik, Herschel Rosenberg, John Smythe, Jane Lougheed, Tapas Mondal, David Chitayat, Brian W McCrindle, Seema Mital
BACKGROUND: The healthcare burden related to congenital heart disease (CHD) is increasing with improving survival. We assessed changing trends in prenatal risk factors for CHD in the current era in a Canadian cohort. METHODS AND RESULTS: CHD patients <18 years old (n=2339) and controls without structural heart disease (n=199) were prospectively enrolled in an Ontario province-wide biobank registry from 2008-2011. Family history, frequency of extra-cardiac anomalies (ECAs), and antenatal risk factors were assessed...
June 2013: Journal of the American Heart Association
https://www.readbyqxmd.com/read/22718458/-ultrasound-and-color-doppler-applications-in-nephrology-the-normal-kidney-anatomy-vessels-and-congenital-anomalies
#12
Mario Meola, Ilaria Petrucci, Lisa Giovannini, Sara Samoni, Carolina Dellafiore
Gray-scale ultrasound is the diagnostic technique of choice in patients with suspected or known renal disease. Knowledge of the normal and abnormal sonographic morphology of the kidney and urinary tract is essential for a successful diagnosis. Conventional sonography must always be complemented by Doppler sampling of the principal arterial and venous vessels. B-mode scanning is performed with the patient in supine, prone or side position. The kidney can be imaged by the anterior, lateral or posterior approach using coronal, transverse and oblique scanning planes...
May 2012: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/22460989/epidemiology-of-urolithiasis-an-update
#13
Alberto Trinchieri
Background & Aim. Changing socio-economic conditions generated changes in the prevalence, incidence and distribution for age, sex and type of urolithiasis in terms of both the site and the chemical-physical composition of the calculi.In the latter part of the 20(th) century the prevalence of upper urinary tract stones was increasing in Western countries whereas endemic infantile bladder stone disease was fairly widespread in huge areas of developing countries. The aim of this paper was to update previous epidemiological reports of urolithiasis by reviewing the more recent literature...
May 2008: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/22054394/maternal-risk-factors-for-congenital-urinary-anomalies-results-of-a-population-based-case-control-study
#14
Margarett Shnorhavorian, Rachel Bittner, Jonathan L Wright, Stephen M Schwartz
OBJECTIVE: Epidemiologic data addressing maternal risk factors for congenital urinary tract anomalies (CUTA) are limited, with conflicting results for preexisting diabetes mellitus, gestational diabetes, and tobacco and alcohol use. The purpose of this study was to examine the association between maternal risk factors and CUTA in a population-based case-control study. METHODS: A case-control analysis was performed using linked birth-hospital discharge records from Washington state for 1987-2007 to evaluate the association between maternal risk factors and CUTA...
November 2011: Urology
https://www.readbyqxmd.com/read/21713537/-is-the-training-and-continuing-education-for-urologists-in-germany-still-up-to-date
#15
S C Müller, T Strunk
Besides its role in bladder and kidney cancer, urology plays a leading part in oncology particularly with regard to prostate cancer, the most frequent malignant tumor found in men. The multitude of hereditary anomalies of the urogenital tract and the resultant medical conditions, the importance of urinary tract infections including the still deadly urosepsis, urolithiasis which has become as widespread a condition as diabetes mellitus, and urinary incontinence as an increasing problem of a continuously aging population play such a large role in routine practice that every practicing physician must acquire the necessary skills for appropriate diagnosis and treatment...
August 2011: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/21089741/genetic-syndrome-suspicion-examples-of-clinical-approach-in-the-neonatal-unit
#16
REVIEW
M Giuffrè, L De Sanctis
Overgrowth syndromes: the practical clinical approach. Excessive growth can be present in a variety of medical conditions as result of abnormal fetal metabolism (i.e., maternal gestational diabetes) or of an overgrowth syndrome. Within this latter group of diseases, a LGA newborn requires a complex differential diagnosis encompassing several syndromes, such as Beckwith-Wiedemman, Sotos, Weaver, Simpson-Golabi-Behmel, Perlman, and Bannayan-Riley-Ruvalcaba. Partial or global overgrowth, other dysmorphisms, abdominal organs anomalies, as well as benign and malignant tumors are the common issues to examine for the diagnosis and the monitoring of all these disorders...
June 2010: Minerva Pediatrica
https://www.readbyqxmd.com/read/20378641/spectrum-of-hnf1b-mutations-in-a-large-cohort-of-patients-who-harbor-renal-diseases
#17
Laurence Heidet, Stéphane Decramer, Audrey Pawtowski, Vincent Morinière, Flavio Bandin, Bertrand Knebelmann, Anne-Sophie Lebre, Stanislas Faguer, Vincent Guigonis, Corinne Antignac, Rémi Salomon
BACKGROUND AND OBJECTIVES: Hepatocyte nuclear factor 1beta (HNF1beta) is a transcription factor that is critical for the development of kidney and pancreas. In humans, mutations in HNF1B lead to congenital anomalies of the kidney and urinary tract, pancreas atrophy, and maturity-onset diabetes of the young type 5 and genital malformations. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We report HNF1B screening in a cohort of 377 unrelated cases with various kidney phenotypes (hyperechogenic kidneys with size not more than +3 SD, multicystic kidney disease, renal agenesis, renal hypoplasia, cystic dysplasia, or hyperuricemic tubulointerstitial nephropathy not associated with UMOD mutation)...
June 2010: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/20192931/clinical-and-laboratory-characteristics-of-acute-community-acquired-urinary-tract-infections-in-adult-hospitalised-patients
#18
Dilista Piljic, Dragan Piljic, Sead Ahmetagic, Farid Ljuca, Humera Porobic Jahic
Urinary tract infections (UTI) cause a great number of morbidity and mortality. These infections are serious complications in pregnancy, patients with diabetes, polycystic kidneys disease, sickle cell anaemia, kidney transplant and in patients with functional or structural anomalies of the urinary tract. The aim of this investigation was to determine a dominant causative agents of UTI and some of the clinical and laboratory characteristics of acute community-acquired UTI in adult hospitalised patients. We studied 200 adult patients with acute community-acquired UTI hospitalised in the Clinic for Infectious Diseases Tuzla from January 2006 to December 2007...
February 2010: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/20175044/deletion-of-hepatocyte-nuclear-factor-1-beta-in-an-infant-with-prune-belly-syndrome
#19
Sina Haeri, Patricia L Devers, Kathleen A Kaiser-Rogers, Vincent J Moylan, Beth S Torchia, Amanda L Horton, Honor M Wolfe, Arthur S Aylsworth
Prune belly syndrome is a rare congenital disorder characterized by deficiency of abdominal wall muscles, cryptorchidism, and urinary tract anomalies. We have had the opportunity to study a baby with prune belly syndrome associated with an apparently de novo 1.3-megabase interstitial 17q12 microdeletion that includes the hepatocyte nuclear factor-1-beta gene at 17q12. One previous patient, an adult, has been reported with prune belly syndrome and a hepatocyte nuclear factor-1-beta microdeletion. Hepatocyte nuclear factor-1-beta is a widely expressed transcription factor that regulates tissue-specific gene expression and is expressed in numerous tissues including mesonephric duct derivatives, the renal tubule of the metanephros, and the developing prostate of the mouse...
August 2010: American Journal of Perinatology
https://www.readbyqxmd.com/read/20140240/mutations-in-slc29a3-encoding-an-equilibrative-nucleoside-transporter-ent3-cause-a-familial-histiocytosis-syndrome-faisalabad-histiocytosis-and-familial-rosai-dorfman-disease
#20
Neil V Morgan, Mark R Morris, Hakan Cangul, Diane Gleeson, Anna Straatman-Iwanowska, Nicholas Davies, Stephen Keenan, Shanaz Pasha, Fatimah Rahman, Dean Gentle, Maaike P G Vreeswijk, Peter Devilee, Margaret A Knowles, Serdar Ceylaner, Richard C Trembath, Carlos Dalence, Erol Kismet, Vedat Köseoğlu, Hans-Christoph Rossbach, Paul Gissen, David Tannahill, Eamonn R Maher
The histiocytoses are a heterogeneous group of disorders characterised by an excessive number of histiocytes. In most cases the pathophysiology is unclear and treatment is nonspecific. Faisalabad histiocytosis (FHC) (MIM 602782) has been classed as an autosomal recessively inherited form of histiocytosis with similarities to Rosai-Dorfman disease (RDD) (also known as sinus histiocytosis with massive lymphadenopathy (SHML)). To elucidate the molecular basis of FHC, we performed autozygosity mapping studies in a large consanguineous family and identified a novel locus at chromosome 10q22...
February 5, 2010: PLoS Genetics
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