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https://www.readbyqxmd.com/read/29679842/context-matters-social-cognition-task-performance-in-psychometric-schizotypes
#1
Madeline J Pflum, Diane C Gooding
Patients with schizophrenia show performance deficits on tasks requiring empathy-related social cognition. The extent to which empathy impairments are observed in psychometric schizotypy is unclear. We compared accuracy and reaction time in three groups of individuals characterized by positive schizotypy (n = 79), negative schizotypy (n = 123), or low schizotypy group (n = 137). On a social cognition task that provided context, namely, the Emotion Perspective Taking Task, the positive schizotypes showed poorer performance than the negative schizotypy and control groups...
April 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29679743/dual-t-1-and-t-2-weighted-magnetic-resonance-imaging-based-on-gd-3-loaded-bioinspired-melanin-dots
#2
Liying Xu, Su Hyun Hong, Yao Sun, Ziyan Sun, Kangquan Shou, Kai Cheng, Hao Chen, Daijuan Huang, Haibo Xu, Zhen Cheng
In this report, a novel T1 /T2 dual modal nanoprobe based on highly efficient and bioinspired melanin dots (M-dots) with directly loading gadolinium (Gd-M-dots) for magnetic resonance imaging (MRI) is described. In vitro and in vivo investigations have revealed that Gd-M-dots showed nontoxicity and good biocompatibilitity. Gd-M-dots relaxivity values on 3 T were determined to be r1 =23.4 and r2 =123.3mM-1 s-1 , which were much higher than both Gd-DTPA (r1 =5.1, r2 =6.2mM-1 s-1 ) and Fe-M-dots (r1 =1.2, r2 =2...
April 18, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29679691/newly-developed-endoscopic-detachable-snare-ligation-therapy-for-colonic-diverticular-hemorrhage-a-multicenter-phase-ii-trial-with-videos
#3
Daisuke Akutsu, Toshiaki Narasaka, Katsumasa Kobayashi, Kenji Matsuda, Mariko Wakayama, Yoshinori Hiroshima, Shinji Endo, Takashi Mamiya, Takahisa Watahiki, Kazuto Ikezawa, Hiroyasu Ishida, Mitsuaki Hirose, Yuji Mizokami, Ichinosuke Hyodo
BACKGROUND AND AIMS: We previously reported preliminary safety results for a new method, endoscopic detachable snare ligation (EDSL), for diverticular hemorrhage. This method does not need endoscope removal to attach a ligation device after detection of the bleeding site. The aim of the present study was to evaluate the efficacy and safety of EDSL in a larger patient population. METHODS: This prospective study was conducted in 12 institutions. Patients suspected of having diverticular hemorrhage without serious systemic disease were enrolled...
April 18, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29678734/polymeric-micelle-mediated-delivery-of-half-sandwich-ruthenium-ii-complexes-with-phosphanes-derived-from-fluoroloquinolones-for-lung-adenocarcinoma-treatment
#4
Przemysław Kołoczek, Agnieszka Skórska-Stania, Agnieszka Cierniak, Victor Sebastian, Urszula K Komarnicka, Michał Płotek, Agnieszka Kyzioł
Novel half-sandwich ruthenium(II) complexes with aminomethyl(diphenyl)phosphine derived from fluoroloquinolones (RuPCp, RuPSf, RuPLm, RuPNr) were being investigated as alternatives to well-established metal-based chemotherapeutics. All compounds were characterized by elemental analysis, selected spectroscopic methods (i.e., absorption and fluorescence spectroscopy, ESI-MS, NMR, circular dichroizm), X-ray diffractometry, ICP-MS, and electrochemical techniques. To overcome low solubility, serious side effects connected with systemic cytotoxicity of ruthenium complexes, and acquiring the resistance of cancer cells, polymeric nanoformulations based on Pluronic P-123 micelles loaded with selected Ru(II) complexes were prepared and characterized...
April 17, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29677014/continuous-electroencephalography-in-the-critically-ill-clinical-and-continuous-electroencephalography-markers-for-targeted-monitoring
#5
Christopher R Newey, Tyler G Kinzy, Vineet Punia, Stephen Hantus
PURPOSE: Electrographic seizures detected by continuous electroencephalography (CEEG) in critically ill patients with altered mental status is becoming increasingly recognized. Data guiding the appropriate selection of patients to be monitored on CEEG are lacking. The aims of this article were to study the incidence of seizures in the critical care setting and to evaluate for clinical predictors to improve the efficiency of CEEG monitoring. METHODS: Retrospective review of the CEEG and clinical data on 1,123 consecutive patients who had continuous video EEG over a 24-month period...
April 17, 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29676689/intravenous-acetaminophen-for-postoperative-supratentorial-craniotomy-pain-a-prospective-randomized-double-blinded-placebo-controlled-trial
#6
Walavan Sivakumar, Michael Jensen, Julie Martinez, Michael Tanana, Nancy Duncan, Robert Hoesch, Jay K Riva-Cambrin, Craig Kilburg, Safdar Ansari, Paul A House
OBJECTIVE Acute pain control after cranial surgery is challenging. Prior research has shown that patients experience inadequate pain control post-craniotomy. The use of oral medications is sometimes delayed because of postoperative nausea, and the use of narcotics can impair the evaluation of brain function and thus are used judiciously. Few nonnarcotic intravenous (IV) analgesics exist. The authors present the results of the first prospective study evaluating the use of IV acetaminophen in patients after elective craniotomy...
April 20, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29676357/is-a-diagnostic-lumbar-puncture-indicated-in-intraocular-retinoblastoma
#7
Sidharth Totadri, Vinay Munikoty, Usha Singh, Radhika Srinivasan, Amita Trehan, Richa Jain, Nandita Kakkar, Akshay Kumar Saxena, Arvind Rajwanshi, Deepak Bansal
Background: Lumbar puncture (LP) is frequently performed in patients with advanced intraocular retinoblastoma. However, this may not be necessary in a significant proportion of patients. Materials and Methods: A file review of patients who were diagnosed with retinoblastoma over a 13-year-period was performed. Patients who underwent LP as part of staging were included in the study. Results: The study included 223 patients. One-third had bilateral retinoblastoma...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29675891/association-of-the-hla-b27-antigen-and-the-ctla4-gene-ct60-rs3087243-polymorphism-with-ankylosing-spondylitis-in-algerian-population-a-case-control-study
#8
C A Dahmani, A Benzaoui, H Amroun, F Mecabih, F Z Sediki, F Zemani-Fodil, M Fodil, W Boughrara, B Mecheti, N Attal, N Mehtar, E Petit-Teixeira, A Boudjema
Ankylosing spondylitis (AS) is a complex inflammatory disease that represents a major health problem both in Algeria and worldwide. Several lines of evidence support that genetic risk factors play a role in AS etiology and the CTLA4 gene has attracted a considerable attention. In this study, we were interested in evaluating the HLA-B27 frequency and in exploring the CTLA4 gene in a sample of the North African population. The dataset of the current study is composed of 81 patients with AS and 123 healthy controls...
April 19, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29675767/high-risk-for-severe-emotional-dysregulation-in-psychiatrically-referred-youth-with-autism-spectrum-disorder-a-controlled-study
#9
Gagan Joshi, Janet Wozniak, Maura Fitzgerald, Stephen Faraone, Ronna Fried, Maribel Galdo, Stephannie L Furtak, Kristina Conroy, J Ryan Kilcullen, Abigail Belser, Joseph Biederman
To assess prevalence and severity of emotional dysregulation (ED) in psychiatrically referred youth with autism spectrum disorder (ASD). ASD youth (N = 123) were compared to youth with attention-deficit/hyperactivity disorder (ADHD) and controls. The majority of psychiatrically referred youth with ASD had positive Child Behavior Checklist-ED (CBCL-ED) profile that was significantly higher than in youth with ADHD (82 vs. 53%; p < 0.001). The severe emotional dysregulation (SED) profile was significantly greater in ASD youth than ADHD (44 vs...
April 19, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29675439/coronary-events-in-patients-presenting-for-repair-of-acute-type-a-aortic-dissection
#10
Paul C Tang, Shahab A Akhter, Satoru Osaki, Lucian Lozonschi, Takushi Kohmoto, Nilto C De Oliveira
Background: Preoperative coronary angiography is often not performed in acute Type A dissection. We examined differences in the incidence of pre-existing coronary disease and subsequent coronary events between patients undergoing acute Type A dissection repair and patients undergoing elective proximal aortic aneurysm repair. Methods: From 2000 to 2015, there were 154 acute Type A dissection repairs and 457 elective proximal aortic aneurysm repairs. We performed a retrospective review to evaluate preoperative coronary disease and postoperative coronary interventions such as percutaneous coronary intervention (PCI) and coronary bypass grafting (CABG)...
June 2017: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/29675243/electronic-modulation-of-transition-metal-phosphide-via-doping-as-efficient-and-ph-universal-electrocatalysts-for-hydrogen-evolution-reaction
#11
Xin Xiao, Leiming Tao, Man Li, Xiaowei Lv, Dekang Huang, Xingxing Jiang, Haiping Pan, Mingkui Wang, Yan Shen
It is highly desirable to develop efficient and low-cost catalysts to minimize the overpotential of the hydrogen evolution reaction (HER) for large-scale hydrogen production from electrochemical water splitting. Doping a foreign element into the host catalysts has been proposed as an effective approach to optimize the electronic characteristics of catalysts and thus improve their electrocatalytic performance. Herein we, for the first time, report vanadium-doped CoP on self-supported conductive carbon cloth (V-CoP/CC) as a robust HER electrocatalyst, which achieves ultra-low overpotentials of 71, 123 and 47 mV to afford a current density of 10 mA cm-2 in 1 M KOH, 1 M PBS and 0...
February 21, 2018: Chemical Science
https://www.readbyqxmd.com/read/29675093/prognostic-value-of-preoperative-lymphocyte-monocyte-ratio-in-patients-with-ovarian-clear-cell-carcinoma
#12
Byung Su Kwon, Dae Hoon Jeong, Jung Mi Byun, Tae Hwa Lee, Kyung Un Choi, Yong Jung Song, Dong Soo Suh, Ki Hyung Kim
Objective: The aim of the present study was to determine the prognostic significances of markers of preoperative systemic inflammatory response (SIR) in patients with ovarian clear cell carcinoma (OCCC). Methods: A total of 109 patients diagnosed with OCCC that underwent primary cytoreductive surgery and adjuvant platinum-based chemotherapy from 2009 to 2012 were enrolled in this retrospective study. SIR markers were calculated from complete blood cell counts determined before surgery. Receiver operating characteristic (ROC) curve analysis was used to determine optimal cut-off values for neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR)...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29674055/determination-of-deuterium-oxide-content-in-water-based-on-luminescence-quenching
#13
J Kucera, P Lubal, S Lis, P Taborsky
Water molecules (H2 O) often reduce luminescence lifetimes of various luminescence probes. The change of lifetime is usually caused by dynamic luminescence quenching induced by O-H oscillators which effectively take away energy from excited molecule. The process can be described by Stern-Volmer equation. We have studied selected luminescence systems where it is possible to detect considerable changes of lifetime in presence/absence of H2 O and D2 O in this work for analytical purposes. We have tested both, inorganic (Ln3+ ) and organic compounds using three different instrumentation in order to find the largest change between τH and τD ...
July 1, 2018: Talanta
https://www.readbyqxmd.com/read/29674050/quantification-of-transformation-products-of-rocket-fuel-unsymmetrical-dimethylhydrazine-in-soils-using-spme-and-gc-ms
#14
Nadezhda V Bakaikina, Bulat Kenessov, Nikolay V Ul'yanovskii, Dmitry S Kosyakov
Determination of transformation products (TPs) of rocket fuel unsymmetrical dimethylhydrazine (UDMH) in soil is highly important for environmental impact assessment of the launches of heavy space rockets from Kazakhstan, Russia, China and India. The method based on headspace solid-phase microextraction (HS SPME) and gas chromatography-mass spectrometry is advantageous over other known methods due to greater simplicity and cost efficiency. However, accurate quantification of these analytes using HS SPME is limited by the matrix effect...
July 1, 2018: Talanta
https://www.readbyqxmd.com/read/29673794/difference-in-risk-of-breast-and-ovarian-cancer-according-to-putative-functional-domain-regions-in-korean-brca1-2-mutation-carriers
#15
Ji Soo Park, Seung-Tae Lee, Jung Woo Han, Tae Il Kim, Eun Ji Nam, Hyung Seok Park
INTRODUCTION: We investigated the relative risk of breast and ovarian cancers related to the putative functional domain regions, obesity, and parity among Korean BRCA1/2 mutation carriers. PATIENTS AND METHODS: We analyzed the clinical characteristics, cancer history, and mutations according to the putative functional domain of BRCA proteins among 229 women with BRCA1/2 mutations who were treated at Yonsei Cancer Center, Severance Hospital between January 2009 and March 2017...
February 20, 2018: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29673659/effect-of-epidural-anesthesia-in-labor-pregnancy-with-cardiovascular-disease
#16
Hiroaki Tanaka, Chizuko Kamiya, Shinji Katsuragi, Kayo Tanaka, Jun Yoshimatsu, Tomoaki Ikeda
OBJECTIVE: We studied the effect and safety of epidural anesthesia during labor in pregnant women with cardiovascular disease. MATERIALS AND METHODS: In the pregnant women with cardiovascular disease, we compared maternal outcome and suppressive effect on blood pressure retrospectively between the epidural group (anesthetized epidurally during labor) and the no-epidural group (not anesthetized epidurally during labor). RESULTS: A total of 277 patients were included in the analyses...
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29673605/rest-tremor-quantification-based-on-fuzzy-inference-systems-and-wearable-sensors
#17
Luis A Sanchez-Perez, Luis P Sanchez-Fernandez, Adnan Shaout, Juan M Martinez-Hernandez, Maria J Alvarez-Noriega
BACKGROUND: Currently the most consistent, widely accepted and detailed instrument to rate Parkinson's disease (PD) is the Movement Disorder Society sponsored Unified Parkinson Disease Rating Scale (MDS-UPDRS). However, the motor examination is based upon subjective human interpretation trying to capture a snapshot of PD status. Wearable sensors and machine learning have been broadly used to analyze PD motor disorder, but still most ratings and examinations lay outside MDS-UPDRS standards...
June 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29673077/maternal-factors-associated-with-offspring-polycystic-ovarian-syndrome
#18
Anne Z Steiner
In this Swedish national registry-based cohort study Valgeirsdottir et al. sought to determine the association between 1) in-utero exposures and 2) birth indices and the subsequent development of polycystic ovarian syndrome (PCOS) after age 15. To do this, they selected 681,123 girls, whose birth was recorded in the Swedish birth registry between 1982 and 1995. They followed the girls in the Swedish Patient Registry until 2010 for a diagnosis of PCOS using International Classification of Diseases (ICD) codes...
April 19, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29672171/prevalence-of-enterotoxin-genes-in-staphylococcus-aureus-isolates-from-pork-production
#19
Yang Zhang, Yage Wang, Rujian Cai, Lei Shi, Chunling Li, He Yan
In this study, 130 Staphylococcus aureus isolates from samples associated with pork production were tested for prevalence of 18 staphylococcal enterotoxin (SE) genes. Approximately 94.6% (123/130) of isolates from different stages of pork production harbored one or more SE genes forming 37 different enterotoxin gene profiles. Seb was present in 60.0% of the S. aureus isolates, the highest among the genes tested. The genes, sed, sej, seo, sep, ser, and seu, were not found. The five classical SE genes (including sea, seb, sec, sed, see) had lower prevalence than the egc gene cluster (seg, sei, sem, sen, seo, or seu)...
April 19, 2018: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/29671874/pain-assessment-by-pupil-dilation-reflex-in-response-to-noxious-stimulation-in-anaesthetized-adults
#20
D Wildemeersch, N Peeters, V Saldien, M Vercauteren, G Hans
BACKGROUND: In response to noxious stimulation, pupillary dilation reflex (PDR) occurs even in anaesthetized patients. The aim of the study was to evaluate the ability of pupillometry with an automated increasing stimulus intensity to monitor intraoperative opioid administration. METHODS: Thirty-four patients undergoing elective surgery were enrolled. Induction by propofol anaesthesia was increased progressively until the sedation depth criteria (SeD) were attained...
April 19, 2018: Acta Anaesthesiologica Scandinavica
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