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Minerva

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https://www.readbyqxmd.com/read/28506917/atrial-antitachycardia-pacing-and-atrial-remodeling-a-substudy-of-the-international-randomized-minerva-trial
#1
Giuseppe Boriani, Raymond Tukkie, Mauro Biffi, Lluis Mont, Renato Ricci, Helmut Pürerfellner, Giovanni Luca Botto, Antonis S Manolis, Maurizio Landolina, Michele Gulizia, J Harrison Hudnall, Lorenza Mangoni, Andrea Grammatico, Luigi Padeletti
BACKGROUND: Atrial tachycardia (AT) and atrial fibrillation (AF) are common in pacemaker patients and are associated with bad prognosis. OBJECTIVE: To evaluate atrial antitachycardia pacing impact on AT/AF induced atrial remodeling, measured by early recurrence of AT/AF (ERAF) and by change in left atrium diameter (LAD). To evaluate impact of AT/AF duration on ERAF incidence. METHODS: Pacemaker patients were randomized to dual-chamber pacing (Control DDDR-385 patients), managed ventricular pacing (MVP-398 patients) or atrial antitachycardia pacing plus MVP (DDDRP+MVP-383 patients)...
May 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495268/the-presence-of-vegf-and-notch2-during-preantral-antral-follicular-transition-in-infantile-rats-anatomical-evidence-and-its-implications
#2
Minerva Carolina Torres-Ortiz, Gabriel Gutiérrez-Ospina, Margarita Gómez-Chavarín, Clara Murcia, Rogelio A Alonso-Morales, Gerardo Perera-Marín
Folliculogenesis is a process that depends on angiogenesis, in which VEGF and Notch signaling pathway members are involved. Although this pathway is present in preantral and antral follicular structures during the second stage of folliculogenesis, this association has not been described. Therefore, this study aimed to identify VEGF and Notch2 in ovary structures of infantile rats after induction of follicular development with a gonadotropin stimulus. In order to explore this possibility we analyzed rat ovary morphology from days 10-25 after birth; subsequently, the transition from preantral follicle to an antral stage was analyzed by the induction of follicular development with equine chorionic gonadotropin (eCG) and VEGF and Notch were identified in the rat ovary by fluorescence...
May 8, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28492846/a-large-right-shoulder-mass
#3
Minerva A Romero Arenas, Sarah B Fisher, Reza J Mehran
No abstract text is available yet for this article.
May 10, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28484686/impact-of-pe_pgrs33-gene-polymorphisms-on-mycobacterium-tuberculosis-infection-and-pathogenesis
#4
Serena Camassa, Ivana Palucci, Raffaella Iantomasi, Tiziana Cubeddu, Mariachiara Minerva, Flavio De Maio, Samuel Jouny, Elisa Petruccioli, Delia Goletti, Francesco Ria, Michela Sali, Maurizio Sanguinetti, Riccardo Manganelli, Stefano Rocca, Priscille Brodin, Giovanni Delogu
PE_PGRS33 is a surface-exposed protein of Mycobacterium tuberculosis (Mtb) which exerts its role in macrophages entry and immunomodulation. In this study, we aimed to investigate the polymorphisms in the pe_pgrs33 gene of Mtb clinical isolates and evaluate their impact on protein functions. We sequenced pe_pgrs33 in a collection of 135 clinical strains, genotyped by 15-loci MIRU-VNTR and spoligotyping and belonging to the Mtb complex (MTBC). Overall, an association between pe_pgrs33 alleles and MTBC genotypes was observed and a dN/dS ratio of 0...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28480329/african-american-exome-sequencing-identifies-potential-risk-variants-at-alzheimer-disease-loci
#5
Aurelie N'Songo, Minerva M Carrasquillo, Xue Wang, Jeremy D Burgess, Thuy Nguyen, Yan W Asmann, Daniel J Serie, Steven G Younkin, Mariet Allen, Otto Pedraza, Ranjan Duara, Maria T Greig Custo, Neill R Graff-Radford, Nilüfer Ertekin-Taner
OBJECTIVE: In African Americans, we sought to systematically identify coding Alzheimer disease (AD) risk variants at the previously reported AD genome-wide association study (GWAS) loci genes. METHODS: We identified coding variants within genes at the 20 published AD GWAS loci by whole-exome sequencing of 238 African American participants, validated these in 300 additional participants, and tested their association with AD risk in the combined cohort of 538 and with memory endophenotypes in 319 participants...
April 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28465807/evaluation-models-and-criteria-of-the-quality-of-hospital-websites-a-systematic-review-study
#6
REVIEW
Fatemeh Rangraz Jeddi, Hamidreza Gilasi, Sahar Khademi
INTRODUCTION: Hospital websites are important tools in establishing communication and exchanging information between patients and staff, and thus should enjoy an acceptable level of quality. The aim of this study was to identify proper models and criteria to evaluate the quality of hospital websites. METHODS: This research was a systematic review study. The international databases such as Science Direct, Google Scholar, PubMed, Proquest, Ovid, Elsevier, Springer, and EBSCO together with regional database such as Magiran, Scientific Information Database, Persian Journal Citation Report (PJCR) and IranMedex were searched...
February 2017: Electronic Physician
https://www.readbyqxmd.com/read/28461730/genetic-and-phytochemical-diversity-analysis-in-bunium-persicum-populations-of-north-western-himalaya
#7
Rakesh Kumar Chahota, Vikas Sharma, Minerva Ghani, Tilak Raj Sharma, Jai Chand Rana, Shyam Kumar Sharma
The present study explores morphological, genetic and phytochemical composition of Bunium persicum populations belonging to high altitudinal areas of Indian Himalayan region. In total, 23 morphological traits (13 quantitative and 10 qualitative traits) and 32 Random Amplified Polymorphic DNA primers were employed to infer the population structure of the species. Of the fourteen populations, five genetically diverse populations were analyzed for phytochemical diversity. Among morphological traits, inflorescence, seed and branch traits were most significant in detecting variation...
April 2017: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/28438783/mistakes-and-missed-opportunities-regarding-cosmetic-surgery-and-conscientious-objection
#8
Toni C Saad
In her paper 'Cosmetic surgery and conscientious objection', Minerva rightly identifies cosmetic surgery as an interesting test case for the question of conscientious objection in medicine. Her treatment of this important subject, however, seems problematic. It is argued that Minerva's suggestion that a doctor has a prima facie duty to satisfy patient preferences even against his better clinical judgment, which we call Patient Preference Absolutism, must be regarded with scepticism. This is because (1) it overlooks an important distinction regarding autonomy's meaning and place in clinical practice, and (2) it makes obsolete the important concepts of expert clinical judgment and beneficence...
April 24, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28428219/deficiency-of-cholesteryl-ester-transfer-protein-protects-against-atherosclerosis-in-rabbits
#9
Jifeng Zhang, Manabu Niimi, Dongshan Yang, Jingyan Liang, Jie Xu, Tokuhide Kimura, Anna V Mattew, Yanhong Guo, Yanbo Fan, Tianqing Zhu, Jun Song, Rose Ackermann, Yui Koike, Anna Schwendeman, Liangxue Lai, Subramaniam Pennathur, Minerva Garcia-Barrio, Jianglin Fan, Y Eugene Chen
OBJECTIVE: CETP (cholesteryl ester transfer protein) plays an important role in lipoprotein metabolism; however, whether inhibition of CETP activity can prevent cardiovascular disease remains controversial. APPROACH AND RESULTS: We generated CETP knockout (KO) rabbits by zinc finger nuclease gene editing and compared their susceptibility to cholesterol diet-induced atherosclerosis to that of wild-type (WT) rabbits. On a chow diet, KO rabbits showed higher plasma levels of high-density lipoprotein (HDL) cholesterol than WT controls, and HDL particles of KO rabbits were essentially rich in apolipoprotein AI and apolipoprotein E contents...
April 20, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28426765/allatotropin-a-pleiotropic-neuropeptide-that-elicits-mosquito-immune-responses
#10
Salvador Hernández-Martínez, Minerva Sánchez-Zavaleta, Kevin Brito, Antonia Herrera-Ortiz, Sheila Ons, Fernando G Noriega
Allatotropins (AT) are neuropeptides with pleotropic functions on a variety of insect tissues. They affect processes such as juvenile hormone biosynthesis, cardiac rhythm, oviduct and hindgut contractions, nutrient absorption and circadian cycle. The present work provides experimental evidence that AT elicits immune responses in two important mosquito disease vectors, Anopheles albimanus and Aedes aegypti. Hemocytes and an immune-competent mosquito cell line responded to AT by showing strong morphological changes and increasing bacterial phagocytic activity...
2017: PloS One
https://www.readbyqxmd.com/read/28425496/3-4-methylenedioxymethamphetamine-increases-affiliative-behaviors-in-squirrel-monkeys-in-a-serotonin-2a-receptor-dependent-manner
#11
Elizabeth G Pitts, Adelaide R Minerva, Erika B Oliver, Jordan N Kohn, Meghan T Logun, Agnieszka Sulima, Kenner C Rice, Leonard L Howell
3,4-methylenedioxymethamphetamine (MDMA) increases sociality in humans and animals. Release of serotonin (5-HT) is thought to play an important role in the increase in social behaviors, but the mechanisms underlying these effects are poorly understood. Despite the advantages of nonhuman primate models, no studies have examined the mechanisms of the social effects of MDMA in nonhuman primates. The behavior and vocalizations of four group-housed squirrel monkeys were examined following administration of MDMA, its enantiomers, and methamphetamine...
April 20, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28401438/resveratrol-induces-mitochondrial-dysfunction-and-decreases-chronological-life-span-of-saccharomyces-cerevisiae-in-a-glucose-dependent-manner
#12
Minerva Ramos-Gomez, Ivanna Karina Olivares-Marin, Melina Canizal-García, Juan Carlos González-Hernández, Gerardo M Nava, Luis Alberto Madrigal-Perez
A broad range of health benefits have been attributed to resveratrol (RSV) supplementation in mammalian systems, including the increases in longevity. Nonetheless, despite the growing number of studies performed with RSV, the molecular mechanism by which it acts still remains unknown. Recently, it has been proposed that inhibition of the oxidative phosphorylation activity is the principal mechanism of RSV action. This mechanism suggests that RSV might induce mitochondrial dysfunction resulting in oxidative damage to cells with a concomitant decrease of cell viability and cellular life span...
April 11, 2017: Journal of Bioenergetics and Biomembranes
https://www.readbyqxmd.com/read/28389185/an-unanticipated-airway-problem-in-a-man-undergoing-femoral-popliteal-bypass
#13
Soo H Kim, Jason C Vitek, Minerva P Kryniak, Paul S Pagel
No abstract text is available yet for this article.
December 20, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28381261/challenges-for-achieving-safe-and-effective-radical-cure-of-plasmodium-vivax-a-round-table-discussion-of-the-apmen-vivax-working-group
#14
Kamala Thriemer, Benedikt Ley, Albino Bobogare, Lek Dysoley, Mohammad Shafiul Alam, Ayodhia P Pasaribu, Jetsumon Sattabongkot, Elodie Jambert, Gonzalo J Domingo, Robert Commons, Sarah Auburn, Jutta Marfurt, Angela Devine, Mohammad M Aktaruzzaman, Nayeem Sohel, Rinzin Namgay, Tobgyel Drukpa, Surender Nath Sharma, Elvieda Sarawati, Iriani Samad, Minerva Theodora, Simone Nambanya, Sonesay Ounekham, Rose Nanti Binti Mudin, Garib Da Thakur, Leo Sora Makita, Raffy Deray, Sang-Eun Lee, Leonard Boaz, Manjula N Danansuriya, Santha D Mudiyanselage, Nipon Chinanonwait, Suravadee Kitchakarn, Johnny Nausien, Esau Naket, Thang Ngo Duc, Ha Do Manh, Young S Hong, Qin Cheng, Jack S Richards, Rita Kusriastuti, Ari Satyagraha, Rintis Noviyanti, Xavier C Ding, Wasif Ali Khan, Ching Swe Phru, Zhu Guoding, Gao Qi, Akira Kaneko, Olivo Miotto, Wang Nguitragool, Wanlapa Roobsoong, Katherine Battle, Rosalind E Howes, Arantxa Roca-Feltrer, Stephan Duparc, Ipsita Pal Bhowmick, Enny Kenangalem, Jo-Anne Bibit, Alyssa Barry, David Sintasath, Rabindra Abeyasinghe, Carol H Sibley, James McCarthy, Lorenz von Seidlein, J Kevin Baird, Ric N Price
The delivery of safe and effective radical cure for Plasmodium vivax is one of the greatest challenges for achieving malaria elimination from the Asia-Pacific by 2030. During the annual meeting of the Asia Pacific Malaria Elimination Network Vivax Working Group in October 2016, a round table discussion was held to discuss the programmatic issues hindering the widespread use of primaquine (PQ) radical cure. Participants included 73 representatives from 16 partner countries and 33 institutional partners and other research institutes...
April 5, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28358174/the-role-of-minimally-invasive-surgery-in-neuroendocrine-pancreatic-tumors
#15
Eugenia Yiannakopoulou
Minimally invasive surgery has an established role in the treatment of patients with pancreatic neuroendocrine tumors (pNETs). Enucleation is an established treatment option for insulinomas. The necessity of organ sparing surgery is well established in the case of multiple pNETs. A number of studies have demonstrated the efficacy and safety of laparoscopic surgery for the treatment of pNETs. However, pNETs are rare, and large studies focusing on pNET patients are difficult to be designed unless multicenter experience is collected...
June 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28327244/how-should-we-tackle-financial-and-prosocial-biases-against-unattractive-people
#16
Francesca Minerva
The fact that attractive people benefit from their good looks is not bad per se. Rather, what is worrisome is the fact that unattractive people are discriminated against, and that such discrimination negatively affects many aspects of their lives. I focus on the moral implications of this discrimination and on the possible measures that could be taken to alleviate it.
January 2017: Behavioral and Brain Sciences
https://www.readbyqxmd.com/read/28315532/oral-chemotherapy-adherence-a-novel-nursing-intervention-using-an-electronic-health-record-workflow%C3%A2
#17
German Rodriguez, Minerva A Utate, George Joseph, Thelma St Victor
In the ambulatory care setting, chemotherapy regimens have become increasingly complex with the combination of induction treatments and oral medications. Nurses at one cancer center implemented an oral adherence tracking documentation system in the electronic health record (EHR). Oncology nurses assessed and monitored adherence to oral chemotherapy at each clinical encounter and during telephone calls and then documented findings in the EHR. After implementing this new standardized approach, adherence rates were captured as a metric for the organization...
April 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28289810/non-odontogenic-tumors-of-the-facial-bones-in-children-and-adolescents-role-of-multiparametric-imaging
#18
REVIEW
Minerva Becker, Salvatore Stefanelli, Anne-Laure Rougemont, Pierre Alexandre Poletti, Laura Merlini
Tumors of the pediatric facial skeleton represent a major challenge in clinical practice because they can lead to functional impairment, facial deformation, and long-term disfigurement. Their treatment often requires a multidisciplinary approach, and radiologists play a pivotal role in the diagnosis and management of these lesions. Although rare, pediatric tumors arising in the facial bones comprise a wide spectrum of benign and malignant lesions of osteogenic, fibrogenic, hematopoietic, neurogenic, or epithelial origin...
April 2017: Neuroradiology
https://www.readbyqxmd.com/read/28255024/cosmetic-surgery-and-conscientious-objection
#19
Francesca Minerva
In this paper, I analyse the issue of conscientious objection in relation to cosmetic surgery. I consider cases of doctors who might refuse to perform a cosmetic treatment because: (1) the treatment aims at achieving a goal which is not in the traditional scope of cosmetic surgery; (2) the motivation of the patient to undergo the surgery is considered trivial; (3) the patient wants to use the surgery to promote moral or political values that conflict with the doctor's ones; (4) the patient requires an intervention that would benefit himself/herself, but could damage society at large...
March 2, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28228444/brown-adipose-tissue-not-just-a-heater
#20
EDITORIAL
Lin Chang, Minerva T Garcia-Barrio, Y Eugene Chen
No abstract text is available yet for this article.
March 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
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