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https://www.readbyqxmd.com/read/29218429/protein-expression-of-pttg1-as-a-diagnostic-biomarker-in-adrenocortical-carcinoma
#1
Minerva Angélica Romero Arenas, Timothy G Whitsett, Anna Aronova, Samuel A Henderson, Janine LoBello, Mouhammed Amir Habra, Elizabeth G Grubbs, Jeffrey E Lee, Kanishka Sircar, Rasa Zarnegar, Theresa Scognamiglio, Thomas J Fahey, Nancy D Perrier, Michael J Demeure
BACKGROUND: Adrenocortical carcinoma (ACC) has a poor prognosis and there is an unmet clinical need for biomarkers to improve both diagnostic and prognostic assessment. Pituitary-tumor transforming gene (PTTG1) has been shown to modulate cancer invasiveness and response to therapy. The potential role of PTTG1 protein levels in ACC has not been previously addressed. We assessed whether increased nuclear protein expression of PTTG1 distinguished ACCs from adrenocortical adenomas (ACAs)...
December 7, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29206228/spatial-relationships-between-above-ground-biomass-and-bird-species-biodiversity-in-palawan-philippines
#2
Minerva Singh, Daniel A Friess, Bruno Vilela, Jose Don T De Alban, Angelica Kristina V Monzon, Rizza Karen A Veridiano, Roven D Tumaneng
This study maps distribution and spatial congruence between Above-Ground Biomass (AGB) and species richness of IUCN listed conservation-dependent and endemic avian fauna in Palawan, Philippines. Grey Level Co-Occurrence Texture Matrices (GLCMs) extracted from Landsat and ALOS-PALSAR were used in conjunction with local field data to model and map local-scale field AGB using the Random Forest algorithm (r = 0.92 and RMSE = 31.33 Mg·ha-1). A support vector regression (SVR) model was used to identify the factors influencing variation in avian species richness at a 1km scale...
2017: PloS One
https://www.readbyqxmd.com/read/29205566/transglutaminase-type-2-plays-a-key-role-in-the-pathogenesis-of-mycobacterium-tuberculosis-infection
#3
I Palucci, I Matic, L Falasca, M Minerva, G Maulucci, M De Spirito, E Petruccioli, D Goletti, F Rossin, M Piacentini, G Delogu
BACKGROUND: Mycobacterium tuberculosis (MTB), the aetiological agent of tuberculosis (TB), is capable of interfering with the phagosome maturation pathway, by inhibiting phagosome-lysosome fusion and the autophagic process to ensure survival and replication in macrophages. Thus, it has been proposed that the modulation of autophagy may represent a therapeutic approach to reduce MTB viability by enhancing its clearance. OBJECTIVE: The aim of this study was to investigate whether transglutaminase type 2 (TG2) is involved in the pathogenesis of MTB...
December 4, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29171674/a-dubious-defense-of-after-birth-abortion-a-reply-to-r%C3%A3-s%C3%A3-nen
#4
Christopher Kaczor
Scholars have offered various critiques of Alberto Giubilini and Francesca Minerva's controversial article, 'After-birth abortion: Why should the baby live?' My book The Ethics of Abortion: Women's Rights, Human Life, and the Question of Justice presents four such critiques. First, Giubilini and Minerva argue from the deeply controversial to the even more controversial. Second, they presuppose a false view of personal identity called body-self dualism. Third, their view cannot secure human equality. And fourth, their account of harm cannot account for harm found in some cases of murder...
November 24, 2017: Bioethics
https://www.readbyqxmd.com/read/29154124/the-effectiveness-and-clinical-outcomes-of-the-minerva-cervical-thoracic-jacket-in-patients-with-type-ii-odontoid-fractures
#5
Sait Öztürk, Fatih Serhat Erol, Bekir Akgün, Metin Kaplan
Background/aim: The objective of this study was to carry out a detailed analysis and assess the outcomes for the Minerva cervical thoracic jacket (CTJ) in patients with type II odontoid fractures who could not be surgically treated. Materials and methods: Twenty-six patients for whom the Minerva CTJ was used rather than surgery for different reasons were included in the study. All patients were fitted with the Minerva CTJ within the first 24 h following diagnosis. The patients were followed 4 weeks after hospital discharge and then at 2-week intervals...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29147596/carotidynia-a-rare-diagnosis-for-unilateral-neck-pain-revealed-by-cross-sectional-imaging
#6
Corrado Santarosa, Salvatore Stefanelli, Roman Sztajzel, Pravin Mundada, Minerva Becker
Idiopathic carotidynia (IC) is a rare and poorly understood syndrome consisting of unilateral neck pain, tenderness, and increased pulsations over the affected carotid bifurcation. A growing body of evidence supports the hypothesis that IC is a distinct clinicopathologic entity with characteristic imaging features. We report the case of a 34-year-old Caucasian male presenting with intense unilateral neck pain in the emergency setting. Computed tomography and ultrasonography revealed fusiform eccentric thickening of the ipsilateral carotid bifurcation without vessel narrowing...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/29132437/hap2-a-novel-gene-in-babesia-bigemina-is-expressed-in-tick-stages-and-specific-antibodies-block-zygote-formation
#7
Minerva Camacho-Nuez, Diego Josimar Hernández-Silva, Elizabeth Jacqueline Castañeda-Ortiz, María Elena Paredes-Martínez, Marisol Karina Rocha-Martínez, María Elizbeth Alvarez-Sánchez, Ricardo Francisco Mercado-Curiel, Gabriela Aguilar-Tipacamu, Juan Mosqueda
BACKGROUND: Bovine babesiosis is a tick-borne disease caused by the protozoan parasites of the genus Babesia. In their host vector, Babesia spp. undergo sexual reproduction. Therefore, the development of sexual stages and the subsequent formation of the zygote are essential for the parasite to invade the intestinal cells of the vector tick and continue its life-cycle. HAP2/GCS1 is a protein identified in plants, protozoan parasites and other organisms that has an important role during membrane fusion in fertilization processes...
November 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29127053/practical-management-of-acne-for-clinicians-an-international-consensus-from-the-global-alliance-to-improve-outcomes-in-acne
#8
Diane M Thiboutot, Brigitte Dréno, Adbullah Abanmi, Andrew F Alexis, Elena Araviiskaia, Maria Isabel Barona Cabal, Vincenzo Bettoli, Flordeliz Casintahan, Steven Chow, Adilson da Costa, Tam El Ouazzani, Chee-Leok Goh, Harald Pm Gollnick, Minerva Gomez, Nobukazu Hayashi, Maria Isabel Herane, Juan Honeyman, Sewon Kang, Lajos Kemeny, Raj Kubba, Julien Lambert, Alison M Layton, James J Leyden, Jose Luis López-Estebaranz, Nopadon Noppakun, Falk Ochsendorf, Cristina Oprica, Beatriz Orozco, Montserrat Perez, Jaime Piquero Martin, Jo-Ann See, Dae Hun Suh, Jerry Tan, Vicente Torres Lozada, Patricia Troielli, Leihong Flora Xiang
No abstract text is available yet for this article.
November 7, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29122969/single-ca-2-transients-versus-oscillatory-ca-2-signalling-limitations-and-benefits
#9
Minerva Ferrer-Buitrago, Davina Bonte, Petra De Sutter, Luc Leybaert, Bjorn Heindryckx
Oocyte activation is a calcium (Ca(2+)) dependent process that has been investigated in depth, in particular regarding its impact in assisted reproduction technology (ART). Following a standard model of signal transduction, Ca(2+) drives the meiotic progression upon fertilization in all species studied to date. However, Ca(2+) changes during oocyte activation are species specific and they can be classified in two modalities based on the pattern defined by the Ca(2+) signature: a single Ca(2+) transient (e.g...
November 9, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/29119877/direct-puncture-onyx-embolization-of-a-large-calvarial-metastasis-with-intracranial-extension-case-report
#10
Minerva H Zhou, Gavin P Dunn, Joshua W Osbun, DeWitte T Cross, Christopher J Moran, Ralph G Dacey, Akash P Kansagra
We report a case of renal cell carcinoma (RCC) metastasis to the calvarium and describe a strategy for percutaneous embolization of hypervascular calvarial tumors with intracranial extension. An elderly patient with history of RCC presented with left-sided weakness. Imaging studies showed a large right frontoparietal calvarial mass with intra- and extracranial extension. The tumor was devascularized by direct puncture tumor embolization using Onyx 18, allowing subsequent operative resection without significant blood loss or the need for flap reconstruction of the scalp...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29110229/recurrence-of-metastatic-pro-insulinoma-nearly-50%C3%A2-years-after-subtotal-pancreatectomy
#11
Minerva A Romero Arenas, Courtney Olsen, James C Yao
No abstract text is available yet for this article.
November 7, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29107053/conserved-brain-myelination-networks-are-altered-in-alzheimer-s-and-other-neurodegenerative-diseases
#12
Mariet Allen, Xue Wang, Jeremy D Burgess, Jens Watzlawik, Daniel J Serie, Curtis S Younkin, Thuy Nguyen, Kimberly G Malphrus, Sarah Lincoln, Minerva M Carrasquillo, Charlotte Ho, Paramita Chakrabarty, Samantha Strickland, Melissa E Murray, Vivek Swarup, Daniel H Geschwind, Nicholas T Seyfried, Eric B Dammer, James J Lah, Allan I Levey, Todd E Golde, Cory Funk, Hongdong Li, Nathan D Price, Ronald C Petersen, Neill R Graff-Radford, Steven G Younkin, Dennis W Dickson, Julia R Crook, Yan W Asmann, Nilüfer Ertekin-Taner
INTRODUCTION: Comparative transcriptome analyses in Alzheimer's disease (AD) and other neurodegenerative proteinopathies can uncover both shared and distinct disease pathways. METHODS: We analyzed 940 brain transcriptomes including patients with AD, progressive supranuclear palsy (PSP; a primary tauopathy), and control subjects. RESULTS: We identified transcriptional coexpression networks implicated in myelination, which were lower in PSP temporal cortex (TCX) compared with AD...
October 26, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/29092474/minerva-a-facility-to-study-microstructure-and-interface-evolution-in-realtime-under-vacuum
#13
Chris Nicklin, Josue Martinez-Hardigree, Adam Warne, Stephen Green, Martin Burt, John Naylor, Adam Dorman, Dean Wicks, Salahud Din, Moritz Riede
A sample environment to enable real-time X-ray scattering measurements to be recorded during the growth of materials by thermal evaporation in vacuum is presented. The in situ capabilities include studying microstructure development with time or during exposure to different environmental conditions, such as temperature and gas pressure. The chamber provides internal slits and a beam stop, to reduce the background scattering from the X-rays passing through the entrance and exit windows, together with highly controllable flux rates of the evaporants...
October 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29075632/open-maximal-mucosa-sparing-functional-total-laryngectomy
#14
Pavel Dulguerov, Naif H Alotaibi, Stephanie Lambert, Nicolas Dulguerov, Minerva Becker
BACKGROUND: Total laryngectomy after (chemo)radiotherapy is associated with a high incidence of fistula and therefore flaps are advocated. The description of a transoral robotic total laryngectomy prompted us to develop similar minimally invasive open approaches for functional total laryngectomy. METHODS: A retrospective study of consecutive unselected patients with a dysfunctional larynx after (chemo)radiation that underwent open maximal mucosal-sparing functional total laryngectomy (MMSTL) between 2014 and 2016 is presented...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29062603/decreased-quality-of-life-and-treatment-satisfaction-in-patients-with-latent-autoimmune-diabetes-of-the-adult
#15
Minerva Granado-Casas, Montserrat Martínez-Alonso, Nuria Alcubierre, Anna Ramírez-Morros, Marta Hernández, Esmeralda Castelblanco, Joan Torres-Puiggros, Didac Mauricio
OBJECTIVES: Our main aim was to assess the quality of life (QoL) and treatment satisfaction (TS) of subjects with LADA (latent autoimmune diabetes of the adult) and compare these measures with those of patients with other diabetes types, i.e., type 1 (T1DM) and type 2 diabetes mellitus (T2DM). METHODS: This was a cross-sectional study with a total of 48 patients with LADA, 297 patients with T2DM and 124 with T1DM. The Audit of Diabetes-Dependent Quality of Life (ADDQoL-19) questionnaire and the Diabetes Treatment Satisfaction Questionnaire (DTSQ) were administered...
2017: PeerJ
https://www.readbyqxmd.com/read/29053055/successful-surgical-repair-and-recovery-in-a-2-week-old-infant-after-birth-related-cervical-fracture-dislocation
#16
Sara Saleh, Kyle I Swanson, Taryn Bragg
Cervical spine injuries are the most common spine injuries in the pediatric population. The authors present the youngest known patient who underwent cervical spine fusion to repair birth trauma-induced cervical fracture dislocation, resulting in spondyloptosis and spinal cord injury. A 2-week-old boy was found to have spondyloptosis and spinal cord injury after concerns arose from reduced movement of the extremities. The patient's birth was complicated by undiagnosed abdominal dystocia, which led to cervical distraction injury...
October 20, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29032366/from-assistive-to-enhancing-technology-should-the-treatment-enhancement-distinction-apply-to-future-assistive-and-augmenting-technologies
#17
Francesca Minerva, Alberto Giubilini
The treatment-enhancement distinction is often used to delineate acceptable and unacceptable medical interventions. It is likely that future assistive and augmenting technologies will also soon develop to a level that they might be considered to provide users, in particular those with disabilities, with abilities that go beyond natural human limits, and become in effect an enhancing technology. In this paper, we describe how this process might take place, and discuss the moral implications of such developments...
October 14, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28980212/injectable-facial-fillers-imaging-features-complications-and-diagnostic-pitfalls-at-mri-and-pet-ct
#18
REVIEW
Pravin Mundada, Romain Kohler, Sana Boudabbous, Laurence Toutous Trellu, Alexandra Platon, Minerva Becker
Injectable fillers are widely used for facial rejuvenation, correction of disabling volumetric fat loss in HIV-associated facial lipoatrophy, Romberg disease, and post-traumatic facial disfiguring. The purpose of this article is to acquaint the reader with the anatomy of facial fat compartments, as well as with the properties and key imaging features of commonly used facial fillers, filler-related complications, interpretation pitfalls, and dermatologic conditions mimicking filler-related complications. The distribution of facial fillers is characteristic and depends on the anatomy of the superficial fat compartments...
October 4, 2017: Insights Into Imaging
https://www.readbyqxmd.com/read/28972100/actinomycetoma-a-therapeutic-challenge
#19
Sylvia Aide Martínez-Cabriales, Jorge Ocampo-Candiani, Esperanza Welsh, Ana Sofía Ayala-Cortés, Minerva Gómez-Flores, Oliverio Welsh
No abstract text is available yet for this article.
September 29, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28968937/lipid-metabolism-and-pro-oxidant-antioxidant-balance-of-halamphora-oceanica-from-the-gulf-of-mexico-exposed-to-water-accommodated-fraction-of-maya-crude-oil
#20
Hugo F Olivares-Rubio, Lucía Salazar-Coria, Minerva Nájera-Martínez, José Luis Godínez-Ortega, Armando Vega-López
Diatoms play key roles in primary production and carbon fixation at a global scale and in some cases these species live on marine ecosystems impacted by crude oil (CO) spills. Halamphora oceanica, a new diatom species from the Southwest of the Gulf of Mexico was isolated and cultured in the laboratory and was exposed to water accommodated fraction (WAF) of different Maya CO loads at 0.01, 0.1, 1 and 10g/L by 96h. A battery of biomarkers involved in oxidative stress (O2•, H2O2, TBARS, ROOH, RC=O, SOD, CAT, GPx), biotransformation and conjugation (total CYP450 activity and GST) moreover fatty acid (FA) metabolism (FA levels, fatty-acid synthase and acyl-CoA oxidase) were measured...
January 2018: Ecotoxicology and Environmental Safety
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