keyword
https://read.qxmd.com/read/38656094/teplizumab-s-breakthrough-a-beacon-of-hope-in-the-battle-against-type-1-diabetes-mellitus
#1
JOURNAL ARTICLE
Shayan Ahmad
No abstract text is available yet for this article.
April 24, 2024: Minerva endocrinology
https://read.qxmd.com/read/38656093/post-covid-19-syndrome-inflammation-and-insulin-resistance-a-retrospective-cohort-study
#2
JOURNAL ARTICLE
Patricia Fierro, David Martín, Emilio Pariente-Rodrigo, Stefanie F Pini, Héctor Basterrechea, Marian Tobalina, Benedetta Petitta, Camila Bianconi, Sara Díaz-Salazar, Merelyn Bonome, Carmen Ramos-Barrón, José L Hernández-Hernández
BACKGROUND: COVID-19-induced diabetes is a novel and enigmatic disease. Our aim was to evaluate a possible relationship between post-COVID-19 syndrome (PCS) and increased insulin resistance (IR) in non-diabetic outpatients after mild COVID-19. METHODS: Repeated measures design. Three evaluations [1E (pre-COVID, baseline), 2E (3 months post-COVID) and 3E (21 months post-COVID)] were performed, directed to PCS+ and PCS- subjects. Triglyceride-glucose (TyG) index ≥8...
April 24, 2024: Minerva endocrinology
https://read.qxmd.com/read/38656092/how-to-standardize-the-diagnostic-approach-to-pituitary-neuroendocrine-tumors
#3
JOURNAL ARTICLE
Sofia Asioli, Federica Guaraldi, Matteo Zoli, Diego Mazzatenta, Chiara Villa
Pituitary tumors present heterogeneous biochemical, clinico-radiological, and histological features. Although histologically benign, a non-negligible number of cases present an unpredictable aggressive behavior with local invasiveness, partial/complete resistance to treatment and/or recurrence after surgery, and, rarely, metastasize, overall leading to a significant increase of morbidity, and, thus, requiring skilled multidisciplinary management in referral Centers. Histopathological diagnosis is essential to stratify cancer patient risk and uniform follow-up among Centers...
April 24, 2024: Minerva endocrinology
https://read.qxmd.com/read/38656089/variational-femoral-vein-nerve-artery-arrangement-at-the-inguinal-region
#4
JOURNAL ARTICLE
Hande Gurbuz, Tuncay Colak
No abstract text is available yet for this article.
April 24, 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38656088/comment-on-comparison-of-shoulder-anterior-capsular-block-and-interscalene-brachial-plexus-block-for-shoulder-arthroscopy-a-preliminary-analysis
#5
JOURNAL ARTICLE
Alireza Shakeri
No abstract text is available yet for this article.
April 24, 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38656087/combined-lumbar-and-sacral-erector-spinae-plane-ls-esp-block-for-hip-fracture-pain-and-surgery
#6
JOURNAL ARTICLE
Francesco Marrone, Pierfrancesco Fusco, Saverio Paventi, Marco Tomei, Simona Lolli, Elisa Chironna, Carmine Pullano
No abstract text is available yet for this article.
April 24, 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38656086/ultrasound-guided-distal-glossopharyngeal-nerve-block-for-post-tonsillectomy-pain-relief-in-adults-a-prospective-randomized-study
#7
JOURNAL ARTICLE
Mohamed S Abdelghany, Gehan M Eid, Aliaa M Belal, Mona B El Mourad
BACKGROUND: We aimed to evaluate the safety and efficacy of the novel distal approach of ultrasound (US)-guided glossopharyngeal nerve (GPN) block at the pharyngeal wall for enhancing the quality of analgesia in patients undergoing tonsillectomy. METHODS: Fifty patients, both male and female, between the ages of 21 and 65, categorized as ASA I-II by the American Society of Anesthesiologists (ASA) and who were scheduled for tonsillectomy, were enrolled in the study...
April 24, 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38656085/a-comparison-of-simplified-acute-physiology-score-ii-and-sepsis-related-organ-failure-assessment-score-for-prediction-of-mortality-after-intensive-care-unit-cardiac-arrest
#8
JOURNAL ARTICLE
Gerrit Jansen, Stefanie Entz, Fee O Holland, Styliani Lamprinaki, Karl-Christian Thies, Rainer Borgstedt, Martin Krüger, Mariam Abu-Tair, Theodor W May, Sebastian Rehberg
BACKGROUND: This study investigates the predictive value and suitable cutoff values of the Sepsis-related Organ Failure Assessment Score (SOFA) and Simplified Acute Physiology Score II (SAPS-II) to predict mortality during or after Intensive Care Unit Cardiac Arrest (ICU-CA). METHODS: In this secondary analysis the ICU database of a German university hospital with five ICU was screened for all ICU-CA between 2016-2019. SOFA and SAPS-II were used for prediction of mortality during ICU-CA, hospital-stay and one-year-mortality...
April 24, 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38655646/freud-s-interpretation-in-medusa-s-head-and-some-alternative-psychoanalytic-implications-of-ovid-s-medusa
#9
JOURNAL ARTICLE
B J Sokol
Freud's very brief 1922 paper on the beheading of Medusa by Perseus wisely concludes with a call for a further examination of the sources of the legend. A now widespread interpretation of this legend is based (often without acknowledgement) on an addition to traditions concerning Medusa made in Ovid's Metamorphoses . It is argued here that this Ovidian innovation has often been misinterpreted, and that a more careful reading of Metamorphoses supports neither a widely alleged exclusively vengeful portrayal of Medusa, nor Freud's portrayal of Medusa's decapitation as solely a pitiable and terrible symbol of castration...
April 2024: International Journal of Psycho-analysis
https://read.qxmd.com/read/38652452/lumbar-intervertebral-disc-degeneration-in-low-back-pain
#10
REVIEW
Abby P Chiu, Catherine Chia, Lars Arendt-Nielsen, Michele Curatolo
Intervertebral disc degeneration is characterized by deterioration in structural support that is potentially followed by stimulated neuronal ingrowth, and dysfunction of cellular physiology in the disc. Discogenic low back pain originates from nociceptors within the intervertebral disc or the cartilage endplate. This narrative review examines the mechanisms of disc degeneration, the association between degeneration and pain, and the current diagnosis and treatment of discogenic low back pain. Mechanisms of disc degeneration include dysregulated homeostasis of the extracellular matrix of the disc, altered spine mechanics, DNA damage, oxidative stress, perturbed cell signaling pathways, and cellular senescence...
April 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38652451/short-term-effects-of-small-volume-saline-infusion-on-acid-base-equilibrium-in-critically-ill-patients
#11
JOURNAL ARTICLE
Davide Chiumello, Tommaso Pozzi, Giulia Catozzi, Mara Chioccola, Federico Cucinotta, Silvia Coppola
BACKGROUND: Short-term acid-base effects of 0.9% saline solution infusion are not well described. Aim of this study was to assess the effects of a fluid challenge with 0.9% saline in critically ill patients according to the Stewart's approach, which allows a precise determination of acid base equilibrium. METHODS: In 40 mechanically ventilated critically ill patients, acid-base variables according to Stewart's approach were measured before and after 30 minutes from the infusion of 0...
April 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38652450/incidence-of-dreaming-during-ciprofol-anesthesia-for-painless-gastroscopy
#12
JOURNAL ARTICLE
Xinyu Cao, Jiejie Zhou, Miaomiao Xu, Bin Wang, Chongya Yang, Jingwei Xiong, Kangli Hui
BACKGROUND: Dreaming is often reported by patients who undergo propofol-based sedation, but there have not been any studies to date focused on the incidence of dreaming and factors associated therewith following the administration of ciprofol anesthesia in patients undergoing painless gastroscopy. The present study was thus developed with the goal of assessing the incidence of dreaming. METHODS: In total, this study enrolled 200 patients undergoing painless gastroscopy...
April 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38652449/analgesic-effects-of-pectoserratus-plane-block-and-intermediate-cervical-plexus-block-for-transaxillary-endoscopic-thyroidectomy-a-prospective-randomized-controlled-trial
#13
RANDOMIZED CONTROLLED TRIAL
Dong Yin, Zongsheng Duan, Peisong Wang, Ruyan Zhao, Shuang Wang, Xinbai Li
BACKGROUND: Transaxillary endoscopic thyroidectomy (TAET) is favored for its favorable cosmetic outcomes and the preservation of anterior cervical function. Despite these benefits, postoperative analgesia has traditionally relied on pharmacological interventions, and regional anesthetic procedures may be an alternative method. This study aimed to evaluate the efficacy of an ultrasound-guided pectoserratus plane block (PSPB) combined with an intermediate cervical plexus block (ICPB) for TAET...
April 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38652448/ultrasound-guided-intersphincteric-space-block-combined-with-spinal-anesthesia-for-hemorrhoidectomy-a-randomized-clinical-trial
#14
RANDOMIZED CONTROLLED TRIAL
Xiaoxia Liang, Xingqing Liu, Ziyang Lin, Aiwu Luo, Xianjie Wen
BACKGROUND: We aimed to compare the analgesic effects and incidence of urinary retention between ultrasound-guided intersphincteric space block combined with low-dose ropivacaine spinal anesthesia and conventional-dose ropivacaine spinal anesthesia post-hemorrhoidectomy. METHODS: Fifty patients aged 20-65 years who underwent elective hemorrhoidectomy were stochastically assigned to one of two groups. Spinal anesthesia was induced with 8 mg ropivacaine, combined with ultrasound-guided intersphincteric space block in the treatment group...
April 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38652446/highlights-of-the-april-2024-issue
#15
EDITORIAL
Franco Cavaliere
No abstract text is available yet for this article.
April 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38647540/investigation-on-the-treatment-of-mandibular-first-molar-with-eight-canals
#16
JOURNAL ARTICLE
Cheng Bi, Baoyin Li, Ge Ye, Wenjun Shang
No abstract text is available yet for this article.
April 22, 2024: Minerva surgery
https://read.qxmd.com/read/38639735/timed-rolling-and-rising-tests-in-duchenne-muscular-dystrophy-ambulant-boys-a-feasibility-study
#17
JOURNAL ARTICLE
Agnieszka Sobierajska-Rek, Joanna Jabłońska-Brudło, Aneta Dąbrowska, Wiktoria Wojnicz, Jarosław Meyer-Szary, Jolanta Wierzba
BACKGROUND: Functional activities are extensively used in motor assessments of patients with Duchenne muscular dystrophy. The role of timed items has been reported as an early prognostic factor for disease progression. However, there are two functional activities that are not widely assessed in clinical practice among Duchenne muscular dystrophy patients: rolling and bed rising. This study aimed to investigate whether the 360-degree roll (roll) and supine to sit-to-edge (bed rise) measurements are feasible tools reflecting the functional status of ambulatory DMD children by establishing possible correlations between validated measures: the Vignos Scale (VS), timed rise from floor and the 6-Minute Walk Test (6MWT)...
April 2024: Minerva pediatrics
https://read.qxmd.com/read/38635304/regional-anesthesia-techniques-for-shoulder-arthroscopy
#18
JOURNAL ARTICLE
Raghuraman M Sethuraman
No abstract text is available yet for this article.
April 18, 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38634053/-ikzf1-plus-is-a-frequent-biomarker-of-adverse-prognosis-in-mexican-pediatric-patients-with-b-acute-lymphoblastic-leukemia
#19
JOURNAL ARTICLE
Joaquin Garcia-Solorio, Juan Carlos Núñez-Enriquez, Marco Jiménez-Olivares, Janet Flores-Lujano, Fernanda Flores-Espino, Carolina Molina-Garay, Alejandra Cervera, Diana Casique-Aguirre, José Gabriel Peñaloza-Gonzalez, Ma Del Rocío Baños-Lara, Ángel García-Soto, César Alejandro Galván-Díaz, Alberto Olaya-Vargas, Hilario Flores Aguilar, Minerva Mata-Rocha, Miguel Ángel Garrido-Hernández, Juan Carlos Solís-Poblano, Nuria Citlalli Luna-Silva, Lena Sarahi Cano-Cuapio, Pierre Mitchel Aristil-Chery, Fernando Herrera-Quezada, Karol Carrillo-Sanchez, Anallely Muñoz-Rivas, Luis Leonardo Flores-Lagunes, Elvia Cristina Mendoza-Caamal, Beatriz Eugenia Villegas-Torres, Vincent González-Osnaya, Elva Jiménez-Hernández, José Refugio Torres-Nava, Jorge Alfonso Martín-Trejo, María de Lourdes Gutiérrez-Rivera, Rosa Martha Espinosa-Elizondo, Laura Elizabeth Merino-Pasaye, María Luisa Pérez-Saldívar, Silvia Jiménez-Morales, Everardo Curiel-Quesada, Haydeé Rosas-Vargas, Juan Manuel Mejía-Arangure, Carmen Alaez-Verson
BACKGROUND: Recurrent genetic alterations contributing to leukemogenesis have been identified in pediatric B-cell Acute Lymphoblastic Leukemia (B-ALL), and some are useful for refining classification, prognosis, and treatment selection. IKZF1plus is a complex biomarker associated with a poor prognosis. It is characterized by IKZF1 deletion coexisting with PAX5 , CDKN2A/2B , or PAR1 region deletions. The mutational spectrum and clinical impact of these alterations have scarcely been explored in Mexican pediatric patients with B-ALL...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38629936/minocycline-to-reduce-inflammation-and-blood-brain-barrier-leakage-in-small-vessel-disease-minerva-a-phase-ii-randomized-double-blind-placebo-controlled-experimental-medicine-trial
#20
JOURNAL ARTICLE
Robin B Brown, Daniel J Tozer, Laurence Loubière, Eric L Harshfield, Young T Hong, Tim D Fryer, Guy B Williams, Martin J Graves, Franklin I Aigbirhio, John T O'Brien, Hugh S Markus
INTRODUCTION: Cerebral small vessel disease (SVD) is a common cause of stroke/vascular dementia with few effective treatments. Neuroinflammation and increased blood-brain barrier (BBB) permeability may influence pathogenesis. In rodent models, minocycline reduced inflammation/BBB permeability. We determined whether minocycline had a similar effect in patients with SVD. METHODS: MINERVA was a single-center, phase II, randomized, double-blind, placebo-controlled trial...
April 17, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
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