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Constantine Scordalakes, Robert delRosario, Andrew Shimer, Russell Stankiewicz
Objective: Compare amenorrhea rate, menstrual symptoms, patient satisfaction, and adverse events in women who underwent endometrial ablation with the NovaSure versus the Minerva radiofrequency ablation systems. Methods: We surveyed 189 premenopausal women (mean 40.8±6.2 years old) who underwent endometrial ablation for abnormal uterine bleeding using the NovaSure (n=97) or Minerva (n=92) systems, at four private US gynecology clinics, and whose procedure date was after July 2015 with follow-up ≥3 months...
2018: International Journal of Women's Health
Charlotte Lybol, Sanne van der Coelen, Anouk Hamelink, Lidewij Ruth Bartelink, Theodoor Elbert Nieboer
STUDY OBJECTIVE: Endometrial ablation using the NovaSure system (Hologic Inc., Marlborough, MA) is 1 of the treatment options for heavy menstrual bleeding (HMB), which has a reported success rate of 81% to 90%. We aimed to identify predictors for NovaSure endometrial ablation failure. This will contribute to a more effective and individualized preoperative counseling. DESIGN: A retrospective multicenter cohort study (Canadian Task Force classification II-2). SETTING: One university hospital and 1 large teaching hospital...
March 14, 2018: Journal of Minimally Invasive Gynecology
Zhang Wangping, Wu Hanbing
RATIONALE: Postpartum hemorrhage is a common complication and difficult problem in obstetrics. Radiofrequency-induced endometrial ablation (RFIEA) widely used in abnormal uterine bleeding and achieved good effects. This article will investigate the effect of RFIEA for treatment of postpartum hemorrhage. PATIENTS CONCERNS: A 26-year-old healthy full-term parturient woman presented with postpartum hemorrhage after vaginal delivery for 11 hours, who was ready to emergency surgery (hysterectomy) 7 hours after inserting an intrauterine balloon into uterine cavity...
December 2017: Medicine (Baltimore)
Shamma Al-Inizi
No abstract text is available yet for this article.
August 9, 2017: International Journal of Gynaecology and Obstetrics
J Ferguson, E Kot, L Thiel, E Karreman, D Rattray, J Thiel
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
Qing Liu, Xiu-Lan Li, Ji-Juan Liu, Xiao-Hong Song, Xiao-Ying Jiang, Wei Li, Hua Zhang, Calvin Q Pan
AIM: Abnormal uterine bleeding (AUB) occurs in 10-30% of women of reproductive age and up to 61% of cirrhotic women. We evaluated the efficacy and safety of endometrial ablation (NovaSure therapy) for AUB in cirrhotic women. METHODS: This prospective, two-arm, observational study enrolled patients for NovaSure treatment, and they were followed for 12 months. Primary measurements were the amenorrhea rate and changes of pictorial blood loss assessment chart (PBLAC) scores at 1-month post-therapy...
December 2016: Journal of Obstetrics and Gynaecology Research
Dan Li, Yajun Wan, Qingling Mu
OBJECTIVE: To investigate the efficacy and safety of NovaSure system for dysmenorrhea and abnormal uterine bleeding of adenomyosis.
 METHODS: A retrospective analysis on 30 patients with adenomyosis, who treated by NovaSure, were carried out. We collected related clinical data before operation and collected postoperative information about dyemenorrhea, menstruation, anemia and uterine volume by visiting outpatient or telephone.
 RESULTS: All patients were followed up for 7 to 31 months after the operation...
January 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Josien P M Penninx, Malou C Herman, Roy F P M Kruitwagen, Annette J F Ter Haar, Ben W Mol, Marlies Y Bongers
OBJECTIVE: To compare the effectiveness of bipolar radiofrequency (Novasure®) ablation and balloon endometrial ablation (Thermablate®). STUDY DESIGN: We performed a multi-center double blind, randomized controlled trial in three hospitals in The Netherlands. Women with heavy menstrual bleeding were randomly allocated to bipolar or balloon endometrial ablation, performed in the office, using a paracervical block. The primary outcome was amenorrhea. Secondary outcome measures were pain, satisfaction, quality of life and reintervention...
January 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
D Athanatos, G Pados, C A Venetis, P Stamatopoulos, D Rousso, D Tsolakidis, C P Stamatopoulos, B C Tarlatzis
PURPOSE OF INVESTIGATION: To compare the efficacy and safety of two different second-generation ablation devices, Novasure impedance control system and microwave endometrial ablation (MEA), in cases of abnormal uterine bleeding (AUB). MATERIALS AND METHODS: This is a randomized controlled trial that took place in a single Gynecological Department of a University Hospital. Sixty-six women with dysfunctional uterine bleeding (DUB), unresponsive to medical treatment, were included in the trial...
2015: Clinical and Experimental Obstetrics & Gynecology
Weili Zhu, Jiaping Mao, Xia Liu
OBJECTIVE: To explore the feasibility, safety and effectiveness of treatment by Novasure system in abnormal uterine bleeding caused by endometrial polyps (AUB-P) or uterine leiomyomas up to 3 cm (AUB-LSM). METHODS: From June 2011 to June 2012, 30 women with abnormal uterine bleeding caused by AUB-P and AUB-LSM were treated by NoveSure system. The clinical efficacies and complications were followed up at months 1, 3, 6, 12. RESULTS: All operations were completed successfully...
February 17, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Jeffrey D Miller, Gregory M Lenhart, Machaon M Bonafede, Cindy M Basinski, Andrea S Lukes, Kathleen A Troeger
OBJECTIVES: Abnormal uterine bleeding (AUB) interferes with physical, emotional, and social well-being, impacting the quality of life of more than 10 million women in the USA. Hysterectomy, the most common surgical treatment of AUB, has significant morbidity, low mortality, long recovery, and high associated health care costs. Global endometrial ablation (GEA) provides a surgical alternative with reduced morbidity, cost, and recovery time. The NovaSure(®) system utilizes unique radiofrequency impedance-based GEA technology...
2015: International Journal of Women's Health
Bianca B Mengerink, Anneke A M van der Wurff, Johanne F ter Haar, Ilse A van Rooij, Johanna M A Pijnenborg
STUDY OBJECTIVE: To determine the prevalence of adenomyosis and deep adenomyosis after NovaSure (Hologic Inc., Newark, DE) endometrial ablation in hysterectomy specimens after NovaSure endometrial ablation failure. DESIGN: Prospective observational study (Canadian Task Force classification II-2). SETTING: The TweeSteden Hospital, a teaching hospital in the south of the Netherlands. PATIENTS: All women who underwent hysterectomy for menorrhagia and/or dysmenorrhea after failure of NovaSure endometrial ablation between November 2007 and January 2011...
February 2015: Journal of Minimally Invasive Gynecology
John A Thiel, M Martha Briggs, Scott Pohlman, Darrien Rattray
OBJECTIVE: To evaluate procedure-related adverse events, post-procedure menstrual bleeding status, and surgical re-intervention in women with a sounded uterine length > 10 cm compared to women with a sounded uterine length ≤ 10 cm who underwent the NovaSure endometrial ablation procedure. METHODS: We conducted a retrospective cohort study of 188 women from a Canadian community-based gynaecology practice. Eighty-seven women had a sounded uterine length > 10 cm, and 101 patients had a sounded length ≤ 10 cm...
June 2014: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Cindy M Basinski, Pamela Price, Jamie Burkhart, Jamie Johnson
Objective: In-office NovaSure(®) after Essure(®) is a clinical paradigm for which physicians are seeking information. A PubMed search (July 2011) revealed no peer-reviewed articles describing this treatment sequence. To address the paucity of data on this topic, patients who had undergone Essure followed by NovaSure in a private practice office between July 1, 2008 and December 31, 2009 were evaluated. The objective was to evaluate safety and feasibility of in-office NovaSure after Essure, and to determine if the effectiveness of either procedure was altered by this treatment sequence...
April 2012: Journal of Gynecologic Surgery
Richard J Gimpelson
This review examines the peer-reviewed literature describing prospective studies that report amenorrhea rates, patient satisfaction, and surgical reintervention rates following the NovaSure® endometrial ablation procedure. A search of the English-language literature published from 2000 to 2011 was conducted using PubMed. Ten prospective studies, six single-arm NovaSure trials, and four randomized controlled trials comparing the NovaSure procedure with other global endometrial ablation modalities met the inclusion criteria and were reviewed...
2014: International Journal of Women's Health
H W Unger, E Megaly, A Dick, A W Horne, S Milne, C West
Impedance-controlled endometrial ablation (NovaSure) is commonly used to treat premenopausal heavy menstrual bleeding in Lothian, Scotland. Using postal questionnaires, we assessed patient satisfaction, treatment success and post-procedure symptoms in a cohort of women who had NovaSure treatment between January 2007 and May 2009. The response rate was 61.2% (115/188): 90.4% (104/115) of women were satisfied and would recommend the procedure; 36.8% (42/114) of women were amenorrhoeic at follow-up (mean = 497 days) and NovaSure significantly improved levels of both menstrual bleeding and pain (p < 0...
May 2014: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Jamie Kroft, Grace Liu
OBJECTIVE: To estimate the clinical and economic effect of using second-generation endometrial ablation devices compared to first-generation devices for treatment of menorrhagia in pre-menopausal women. The secondary objective was to compare the second-generation devices with one another. DATA SOURCES: We searched Medline and EMBASE, and other sources of unpublished literature, and screened references from relevant articles. STUDY SELECTION: We included only randomized controlled trials or full economic evaluations of premenopausal women with menorrhagia undergoing endometrial ablation using first-generation compared with second-generation devices...
November 2013: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Royce T Adkins, Phillip L Bressman, Patricia B Bressman, Theresa L Lucas
STUDY OBJECTIVE: To assess adverse events associated with radiofrequency endometrial ablation in treatment of heavy menstrual bleeding in patients with a history of low transverse cesarean delivery (C-section group) and patients who delivered vaginally (vaginal delivery group). DESIGN: Retrospective cohort study (Canadian Task Force classification II-2). SETTING: Community-based gynecology practice in the United States. PATIENTS: The study included 194 patients (100 in the C-section group and 94 in the vaginal delivery group), aged 21 to 55 years, with a history of heavy menstrual bleeding...
November 2013: Journal of Minimally Invasive Gynecology
Larry R Glazerman
Until the 1980s, the only available definitive treatment for heavy menstrual bleeding (HMB) was hysterectomy, usually performed abdominally, and sometimes vaginally. Historically, multiple attempts to effect ablation of the endometrium were developed, including using steam and toxic chemicals, such as chloriquine. The advent of Nd-YAG laser endometrial ablation in the mid-1980s offered the first minimally invasive alternative to hysterectomy for the treatment of HMB. Nd-YAG ablation, however, was expensive, cumbersome, and difficult to learn; rollerball resectoscopic ablation was initially described by DeCherney in 1987, and soon overtook laser as the main method of ablation, although adoption continued to be limited because of the hysteroscopic skills necessary to perform the technique were not widely available...
September 2013: Surgical Technology International
Malou C Herman, Marian J van den Brink, Peggy M Geomini, Hannah S van Meurs, Judith A Huirne, Heleen P Eising, Anne Timmermans, Johanna M A Pijnenborg, Ellen R Klinkert, Sjors F Coppus, Theodoor E Nieboer, Ruby Catshoek, Lucet F van der Voet, Hugo W F van Eijndhoven, Giuseppe C M Graziosi, Sebastiaan Veersema, Paul J van Kesteren, Josje Langenveld, Nicol A C Smeets, Huib A A M van Vliet, Jan Willem van der Steeg, Yvonne Lisman-van Leeuwen, Janny H Dekker, Ben W Mol, Marjolein Y Berger, Marlies Y Bongers
BACKGROUND: Heavy menstrual bleeding is an important health problem. Two frequently used therapies are the levonorgestrel intra-uterine system (LNG-IUS) and endometrial ablation. The LNG-IUS can be applied easily by the general practitioner, which saves costs, but has considerable failure rates. As an alternative, endometrial ablation is also very effective, but this treatment has to be performed by a gynaecologist. Due to lack of direct comparison of LNG-IUS with endometrial ablation, there is no evidence based preferred advice for the use of one of these treatment possibilities...
August 8, 2013: BMC Women's Health
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