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https://www.readbyqxmd.com/read/29771829/repairing-a-facial-cleft-by-polyether-ether-ketone-implant-combined-with-titanium-mesh
#1
Yuan Deng, Weiwei Tang, Zhengkang Li
The Tessier Number 4 cleft is one of the rarest, most complex craniofacial anomalies that presents difficulties in surgical treatment. In this article, we report a case of simultaneous facial depression, eye displacement, and medial canthus deformity. In this case, the maxillary bony defect was reconstructed using computer-assisted design computer-assisted manufacturing (CAD-CAM) polyether-ether-ketone (PEEK) material, and the orbital floor defect was repaired with AO prefabricated titanium mesh. Additionally, the medial canthus was modified with canthopexy and a single Z-plasty flap...
May 15, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29746154/psychosocial-functioning-of-children-in-a-craniofacial-support-group
#2
Alexis L Johns, Laura Bava
OBJECTIVE: To describe psychosocial functioning before and after participation in support groups for pediatric patients with craniofacial diagnoses and their families. DESIGN: Baseline and postgroup outcomes and comparison to test norms. SETTING: Urban children's hospital. PARTICIPANTS: Patients (N = 138) were 54% female, primarily Latino (83%), aged 7 to 18 years (mean = 10.4, standard deviation = 2.8), and had public insurance (72%)...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29742253/the-maxillary-lateral-incisor-in-the-rehabilitation-of-cleft-lip-and-palate
#3
Guida Paola Genovez Tereza, Marcos Antônio Corrêa Dos Santos, Vivian Patricia Saldias Vargas Winckler, Ana Lúcia Pompeia Fraga de Almeida, Gisele da Silva Dalben
Objective This study analyzed the maintenance of lateral incisors in the dental rehabilitation of individuals with cleft lip and palate. Material and Methods The study was conducted on a tertiary craniofacial center and comprised retrospective analysis of panoramic and periapical radiographs of Caucasoid individuals with non-syndromic complete unilateral cleft lip and palate, analyzing all radiographs available on the records of each individual, from the first to the last up to 12 years of age. Overall, 2,826 records were reviewed to achieve a sample of 1,000 individuals...
2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29738288/association-between-dlx4-polymorphisms-and-nonsyndromic-orofacial-clefts-in-a-chinese-han-population
#4
Miao He, Zhuan Bian
OBJECTIVE: Distal-less 4 ( DLX4) was recently identified as the causative gene for a syndromic form of cleft lip with or without cleft palate, and further biological analyses have established the importance of Dlx4 gene in craniofacial development, which suggested DLX4 as a promising candidate to further investigate any possible association between DLX4 polymorphisms and risk to nonsyndromic orofacial clefts (NSOFCs). DESIGN: Single-nucleotide polymorphisms (SNPs) with minor allele frequency >5% in the Han Chinese population which locate in the 5' flanking region, 5'/3'-untranslated region, or coding region with nonsynonymous changes in DLX4 were selected...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29733966/transcriptome-profiling-reveals-candidate-cleft-palate-related-genes-in-cultured-chinese-sturgeons-acipenser-sinensis
#5
Jing Yang, Yacheng Hu, Kan Xiao, Xueqing Liu, Chun Tan, Binzhong Wang, Hejun Du
The Chinese sturgeon (Acipenser sinensis) is an anadromous fish distributed in the Yangtze River and the East China Sea. In this study, we report the novel finding of cleft palates in Chinese sturgeons derived from artificial fertilization. To explore the genetic basis of palate malformation in A. sinensis, Illumina RNA-seq technology was used to analyze the transcriptome data of farmed Chinese sturgeons with normal palates and cleft-palates. Raw reads were obtained and assembled into 808,612 unigenes, with an average length of 509...
May 4, 2018: Gene
https://www.readbyqxmd.com/read/29727220/repair-of-primary-cleft-palate-and-oronasal-fistula-with-acellular-dermal-matrix-a-systematic-review-and-surgeon-survey
#6
Andrew Simpson, Osama A Samargandi, Alison Wong, M Elise Graham, Michael Bezuhly
OBJECTIVE: The current review and survey aim to assess the effectiveness of acellular dermal matrix (ADM) in the repair of cleft palate and oronasal fistula and to evaluate the current trends of ADM use in palate surgery. DESIGN: A systematic review of English articles was conducted using MEDLINE (1960 to July 1, 2016), the Cochrane Controlled Trials Register (1960 to July 1, 2016), and EMBASE (1991 to July 1, 2016). Additional studies were identified through a review of references cited in initially identified articles...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29719267/high-resolution-epigenomic-atlas-of-human-embryonic-craniofacial-development
#7
Andrea Wilderman, Jennifer VanOudenhove, Jeffrey Kron, James P Noonan, Justin Cotney
Defects in patterning during human embryonic development frequently result in craniofacial abnormalities. The gene regulatory programs that build the craniofacial complex are likely controlled by information located between genes and within intronic sequences. However, systematic identification of regulatory sequences important for forming the human face has not been performed. Here, we describe comprehensive epigenomic annotations from human embryonic craniofacial tissues and systematic comparisons with multiple tissues and cell types...
May 1, 2018: Cell Reports
https://www.readbyqxmd.com/read/29708801/erratum
#8
(no author information available yet)
Kawamoto H. 2017 Whitaker Lecture: History of the American Society of Craniofacial Surgery. Cleft Palate Craniofac J. 2018;55:8-11. (Original DOI: 10.1177/1055665617740350 ) In the January 2018 issue of The Cleft Palate-Craniofacial Journal, Table 3 on page 10 contained several errors. The corrected Table 3 appears below: [Table: see text].
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29708800/birth-prevalence-of-orofacial-clefts-in-kuwait-from-hospital-based-registration-retrospective-study
#9
Wasmiya A Alhayyan, Sharat C Pan, Fawzi M AlQatami
INTRODUCTION: Cleft lip and palate (CLAP) are the most common craniofacial anomalies and birth defects globally. Despite the fact that a tertiary care registry of clefts has existed in Kuwait since 2008, to date there is no published data regarding the prevalence of orofacial clefts in this population. OBJECTIVE: To tabulate the pattern of orofacial clefts from tertiary care center registration during 2009 through 2014 and to estimate the prevalence and trend using population-based records...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29707444/applications-of-computer-technology-in-complex-craniofacial-reconstruction
#10
Kristopher M Day, Kyle S Gabrick, Larry A Sargent
Background: To demonstrate our use of advanced 3-dimensional (3D) computer technology in the analysis, virtual surgical planning (VSP), 3D modeling (3DM), and treatment of complex congenital and acquired craniofacial deformities. Methods: We present a series of craniofacial defects treated at a tertiary craniofacial referral center utilizing state-of-the-art 3D computer technology. All patients treated at our center using computer-assisted VSP, prefabricated custom-designed 3DMs, and/or 3D printed custom implants (3DPCI) in the reconstruction of craniofacial defects were included in this analysis...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29697637/impact-of-a-cleft-and-craniofacial-center-on-an-academic-health-system-correction
#11
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29697619/the-skoog-lip-repair-for-unilateral-cleft-lip-deformity-the-uppsala-experience
#12
Alberto Falk-Delgado, Anna Lång, Malin Hakelius, Valdemar Skoog, Daniel Nowinski
BACKGROUND: The Uppsala Craniofacial Center has been treating patients with unilateral cleft lip deformity using the lip repair technique described by Tord Skoog. The aim of this study was to determine complications after lip surgery and the incidence and indications for lip revisions in all patients born with unilateral cleft lip from 1960 to 2004. METHODS: All patients who were born from 1960 to 2004 with unilateral cleft lip, cleft lip and alveolus, or cleft lip and palate and underwent lip repair were studied retrospectively...
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29694940/gene-gene-interaction-for-nonsyndromic-cleft-lip-with-or-without-cleft-palate-in-chilean-case-parent-trios
#13
José Suazo, José Luis Santos, Alicia Colombo, Rosa Pardo
OBJECTIVE: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a birth defect for which several genes susceptibility genes been proposed. Consequently, it has been suggested that many of these genes belong to common inter-related pathways during craniofacial development gene-gene interaction. We evaluated the presence of gene-gene interaction for single nucleotide polymorphisms within interferon regulatory factor 6 (IRF6), muscle segment homeobox 1 (MSX1), bone morphogenetic protein 4 (BMP4) and transforming growth factor 3 (TGFB3) genes in NSCL/P risk in Chilean case-parent trios...
April 18, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29679588/growth-and-development-of-craniofacial-structures-in-patients-at-different-ages-with-unrepaired-submucous-cleft-palate
#14
Congcong Cao, Xue Xu, Qian Zheng, Bing Shi, Jingtao Li, Yan Wang
PURPOSE: Submucous cleft palate (SMCP) is a particular subtype of cleft palate deformity; research related to the craniofacial features of patients with SMCP is comparatively rare. The study objective was to perform a cephalometric comparison of the craniofacial features of patients with SMCP and non-cleft controls at different ages. MATERIALS AND METHODS: The sample in this cross-sectional study was composed of 2 groups: SMCP patients and non-cleft controls. The primary predictor variables were study group (cleft and non-cleft) and age...
March 28, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29675824/lamellation-in-fibrous-dysplasia-a-clinicopathologic-study
#15
Ali Fuat Cicek, Melih Kilinc, Mukerrem Safali, Omer Gunhan
BACKGROUND: Fibrous dysplasia (FD) is a maturation defect characterized by immature woven bones and stroma. However, especially in craniofacial bones, lamellation can be seen and this is associated with the maturation. AIM: To show maturation in FD and discuss the factors that may affect the maturation. MATERIALS AND METHODS: Ninety-five FD cases were divided into three subgroups according to the lamellation percentage as Groups 1, 2 and 3 (low, moderate and high lamellation, respectively)...
April 20, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29673851/the-use-of-allogeneic-cartilage-for-grafting-in-functional-and-reconstructive-rhinoplasty
#16
Andrew M Read-Fuller, David M Yates, Alaaaldin Radwan, Alexander M Schrodt, Richard A Finn
PURPOSE: Allogeneic cartilage grafting has multiple uses in rhinoplasty. Autogenous cartilage is frequently used in cases of nasal obstruction or reconstruction, but harvesting grafts can cause complications or might be contraindicated. Rhinoplasties of the patient with cleft might require costochondral grafts. Allogeneic rib is an effective and safe alternative to autogenous grafts, prevents complications, and obviates postoperative admission after rib harvest. MATERIALS AND METHODS: Patients who had allogeneic cartilage placed during functional or reconstructive rhinoplasty were studied from 2 institutions, including 19 who had functional rhinoplasty using allogeneic Cartiform patellar cartilage grafts and 15 patients who underwent reconstructive cleft rhinoplasty with allogeneic rib cartilage...
March 27, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29665341/the-median-mandibular-symphysis-tessier-30-cleft-3d-imaging-analysis-and-review-of-the-literature
#17
Siddharth Mahajan, Pravin K Patel, Yao Duan, Neil Warshawsky
Atypical craniofacial clefts of the upper facial region have been well documented; however, the mandibular clefts remain rare and reported as isolated case reports. We report a case of a median mandibular cleft within the context of a Tessier 0-14 axis that we have followed over a 5-year period without surgical/orthodontic intervention. The mandibular symphysis cleft remained open without evidence of the fusion, in contrast to ossification of the metopic dysraphism. Within this context, we present a review of the median mandibular cleft cases from 1819 to 2015...
May 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29664137/msh-homeobox-1-polymorphisms-and-the-risk-of-non-syndromic-orofacial-clefts-a-meta-analysis
#18
Min Gu, Yan Zhang, Hualian Liu, Jue Liu, Danxia Zhu, Xu Yang
MSH homebox 1 (MSX1) is a susceptibility gene for non-syndromic orofacial clefts (NSOCs). Here, a meta-analysis was conducted to assess their associations. A systematic search of PubMed to 1 September 2017, was performed to retrieve all eligible studies. Odds ratios (ORs) were used to calculate the associations. The stability of the results was evaluated by sensitivity analysis. Publication bias was assessed using Begg's funnel plots and the Egger test. In silico Msx1 expression during early mouse craniofacial development was evaluated by the Gene Expression Omnibus...
April 17, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29652532/comparing-psychological-adjustment-across-cleft-and-other-craniofacial-conditions-implications-for-outcome-measurement-and-intervention
#19
Nicola Marie Stock, Kristin Billaud Feragen
Although cleft lip and/or palate (CL/P) has been a focus of psychological research for a number of years, investigation of adjustment to other, rarer craniofacial anomalies (CFAs) has been scarce. Yet, many features of the journey experienced by patients with CL/P could also have relevance for those affected by other CFAs and vice versa. This brief article summarizes the literature pertaining to psychological adjustment across both craniofacial groups, as represented by several prominent review articles. Similarities across the 2 patient groups in relation to key domains of psychological adjustment and corresponding factors are identified...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29652530/assessing-psychological-adjustment-to-congenital-craniofacial-anomalies-an-illustration-of-methodological-challenges
#20
Nicola Marie Stock, Kristin Billaud Feragen
BACKGROUND: Recognition of the challenges inherent in psychology research related to cleft lip and/or palate (CL/P) and other craniofacial anomalies (CFAs) is far from novel; yet these challenges continue to limit progress within the field. The aim of the present article was to illustrate these challenges by utilizing data extracted from 2 recent literature reviews pertaining to psychological adjustment within CL/P and CFA research. DESIGN: Data relating to 148 CL/P and 41 CFA studies were extracted, summarized, and compared, using percentages, figures, and χ2 calculations...
January 1, 2018: Cleft Palate-craniofacial Journal
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