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Damage reanimation

Sertac Yetiser
Hypoglossal-facial anastomosis provides excellent motor supply to the mimetic muscles of the face when there is no chance of recovery of the damaged facial nerve. However, to achieve optimal results, the timing of facial nerve surgery based on electrophysiological testing and clinical evaluation requires close follow-up of the patient. Functional results after delayed surgery are not predictable and depend on the number of surviving fibers, type of injury, severity of damage, degree of infiltration of inflammatory cells, and local fibrosis...
December 27, 2017: Journal of Craniofacial Surgery
Jasmin Hasmik Shahinian, Jonas Quitt, Mark Wiese, Friedrich Eckstein, Oliver Reuthebuch
BACKGROUND: Mechanical chest compression using a piston device during reanimation is often the only way to ensure stable chest compression at a constant rate and force. However, its use can be associated with severe fractures of the thoracic rib cage and endanger the clinical course of the patient. Thus, the usage of such a piston device during the reanimation has currently been classified as a mere Class IIB indication. CASE PRESENTATION: We present a case of a 66-year-old male who underwent emergent CABG surgery after receiving out-of-hospital resuscitation as a result of myocardial infarction using the LUCAS system...
September 7, 2017: Journal of Cardiothoracic Surgery
Benedict Kjaergaard, Cristian Sevcencu, Sigridur Olga Magnusdottir, Henrik Bygum Krarup, Thomas Nørgaard Nielsen
OBJECTIVES: Surviving long lasting cardiac arrest following accidental hypothermia has been reported after treatment with extra corporeal life support (ECLS), but there is a risk of neurologic injury. Most surviving hypothermia patients have a prolonged stay in the intensive care unit, where most patients experience polyneuropathy. Theoretically, accidental hypothermic cardiac arrest may in itself contribute to polyneuropathy. This study was designed to examine the impact of three hours of cardiac arrest at a core temperature of 20°C followed by reanimation of peripheral nerve function...
February 2017: Journal of Thermal Biology
Alice S Ferng, David Schipper, Alana M Connell, Katherine M Marsh, Shannon Knapp, Zain Khalpey
BACKGROUND: Heart transplantation remains the gold standard for end-stage heart failure, with current ex vivo organ storage times limited to 4 to 6 h before critical tissue damage occurs. Many preservation solutions exist in an attempt to limit both ischemic and reperfusion damage. In order to compare the effects of various storage solutions, mitochondrial function can be used to provide a sensitive analysis of cellular metabolic function. METHODS: Experimental plates were seeded with cardiac myoblasts and kept in suspended animation for either 4 or 8 h at either 4(o) or 21 °C, in Celsior®, Perfadex®, or Somah storage solutions...
January 26, 2017: Journal of Cardiothoracic Surgery
Valentina La Corte, Géraldine Delarue, Emmanuel Chevrillon, Aurore Balan, Béatrice Garcin
OBJECTIVE: Confabulations are described as "a falsification of memory occurring in clear consciousness in association with an organically derived amnesia". We describe production of confabulations in long-term memory in a 51-year-old woman who do not present amnesic syndrome typically associated. The patient was admitted in reanimation unit for septic shock. After 8 days of coma, she presented signs of encephalopathy of Gayet-Wernicke, without cerebral damage on T1 MRI. OBSERVATIONS: At 6 months of acute episode, the patient presents a severe cognitive and behavioural dysexecutive syndrome, with impulsivity, perseverations and environmental dependency...
September 2016: Annals of Physical and Rehabilitation Medicine
Tinen L Iles, Brian Howard, Stephen Howard, Stephen Quallich, Christopher Rolfes, Eric Richardson, Hanna R Iaizzo, Paul A Iaizzo
To date, many pharmacological agents used to treat or prevent arrhythmias in open-heart cases create undesired systemic side effects. For example, antiarrhythmic drugs administered intravenously can produce drops in systemic pressure in the already compromised cardiac patient. While performing open-heart procedures, surgeons will often either create a small port or form a pericardial cradle to create suitable fields for operation. This access yields opportunities for target pharmacological delivery (antiarrhythmic or ischemic preconditioning agents) directly to the myocardial tissue without undesired side effects...
July 7, 2016: Journal of Visualized Experiments: JoVE
Jennifer Kim
Facial paralysis can have a profound effect on the patient from both an aesthetic and functional point of view. Just as there are numerous etiologies of facial paresis, there are as many therapeutic options and variations of these options. The purpose of this article was to review the most current surgical options for neural reanimation of a damaged facial nerve, including recent advances in nerve repair, conduit technology, and nerve transfers, as well as emerging technology in translational research with biomedical engineering and tissue engineering...
February 2016: Facial Plastic Surgery Clinics of North America
R Mustafin, A Bakirov
The article presents the functional characteristics of lung tissue in reanimation profile patients with different pathologies with forced ventilation and auxiliary support on the background. The aim of this study was to analyze the dynamics properties of lung tissue in intensive care unit patients with symptoms of severe violations of restrictive lung tissue being on ventilatory support. Results were subjected to analysis of acid-base status and dynamics of the main indicators of the biomechanical properties of the lung in 32 patients with severe concomitant injury (n=21), acute bilateral community-acquired pneumonia (n=7), septic shock (n=4) during the entire period of the respiratory "prosthetics "(before and after the beginning of mechanical ventilation)...
September 2015: Georgian Medical News
Sameep Kadakia, Samuel Helman, Masoud Saman, Nisha Cooch, Donald Wood-Smith
OBJECTIVES: Individuals with nerve transection face unpredictable outcomes, and microsurgical interventions have variable success. The facial nerve in particular is prone to traumatic transection and leads to debilitating sequelae. Surgeons have used multiple modalities of enhancing nerve regeneration and restoring premorbid functionality. The success of nerve regeneration is predicated on multiple physiologic factors. This article sought to collate the literature on factors influencing nerve damage and repair, using the facial nerve as a paradigm...
June 2015: Journal of Craniofacial Surgery
Nagahiro Takahashi, Koichi Watanabe, Noriyuki Koga, Hideaki Rikimaru, Kensuke Kiyokawa, Tsuyoshi Saga, Moriyoshi Nakamura, Yoko Tabira, Koh-Ichi Yamaki
BACKGROUND: The latissimus dorsi (LD) muscle flap has been widely used in facial reanimation surgery. However, there are no standards to what degree the muscle flap may be safely thinned because the three-dimensional positional relationship of thoracodorsal artery, vein, and nerve inside the LD muscle is poorly understood. METHODS: From 18 formalin-fixed cadavers, we made 36 transparent specimens of LD muscles using a newly developed decoloration technique. In 26 specimens, nerve staining (Sihler's staining method) and silicone rubber (Microfil) injection to the thoracodorsal artery were performed, and the relationship of the artery and the vein was examined in 10 specimens...
May 2013: Plastic and Reconstructive Surgery. Global Open
S K Lowalekar, H Cao, X-G Lu, P R Treanor, H S Thatte
Organ preservation at 4°C results in temporally irreversible injury to cellular structure and function. This study was designed to evaluate the possibility of storing hearts at ambient temperatures in novel organ preservation solution Somah to prevent damage and preserve optimum function by maintaining cellular energy over the temperature range of storage. Porcine hearts were stored in Celsior at 4°C and Somah at 4°C, 13°C and 21°C for 5 h thereafter reperfused and reanimated in vitro for 3 h. Heart weights, histopathology, ultrastructure and 2-dimensional echocardiography (2D-Echo) assessments showed preservation of structure in Somah groups...
October 2014: American Journal of Transplantation
Fabiana Allevi, Paolo Fogagnolo, Luca Rossetti, Federico Biglioli
Patients affected by facial palsy suffer from failure to fully close the eyelids; the resulting eye exposure can lead to dry eye syndrome, loss of epithelial integrity, corneal ulceration and infections. Corneal anaesthesia exacerbates risk of corneal damage in these patients. Eyelid paralysis-associated corneal lesions may induce severe visual impairment, for which the ideal treatment is corneal transplantation, a procedure contraindicated in patients with corneal sensitivity and inadequate eyelid closure...
2014: BMJ Case Reports
Jonas B Zimmermann, Andrew Jackson
As yet, no cure exists for upper-limb paralysis resulting from the damage to motor pathways after spinal cord injury or stroke. Recently, neural activity from the motor cortex of paralyzed individuals has been used to control the movements of a robot arm but restoring function to patients' actual limbs remains a considerable challenge. Previously we have shown that electrical stimulation of the cervical spinal cord in anesthetized monkeys can elicit functional upper-limb movements like reaching and grasping...
2014: Frontiers in Neuroscience
Ia L Zaruts'kyĭ, I R Trutiak
In 91 injured persons, suffering severe closed combined abdominal trauma, the staged surgical treatment was conducted, in 41 of them the operation was performed during one narcosis, but with surgical pause after temporary stopping of hemorrhage, in 50 the "damage control surgery" was applied. Unstable critical state of the injured persons, "unfavorable" prognosis of course of an acute period of the traumatic disease served as indications for the staged surgical treatment conduction. While the urgent laparotomy performance the surgical manipulations were conducted in minimal volume, surgical pause was applied with the patient's state reestimation...
October 2013: Klinichna Khirurhiia
Florian Doepp Connolly, Johanna Reitemeier, Christian Storm, Dietrich Hasper, Stephan J Schreiber
AIM: Despite successful resuscitation, cardiac arrest (CA) often has a poor clinical prognosis. Different diagnostic tools have been established to predict patients' outcome. However, their sensitivity remains low. Assessment of cerebral perfusion by duplex ultrasound might provide additional information regarding the extent of neuronal damage. The aim of the present study was to analyse the changes of global cerebral blood flow (CBF) and intracranial blood flow parameters in the acute stage after CA and its correlation with patients' outcome...
April 2014: Resuscitation
Paulo A S Armada-da-Silva, Cátia Pereira, Sandra Amado, António P Veloso
Despite the great regenerative ability of the peripheral nervous system (PNS), traumatic peripheral nerve damage often causes severe chronic disability. Rehabilitation following PNS trauma usually employs therapeutic exercise in an attempt to reanimate the target organs and stimulate functional recovery. Over the past years, important neurobiological determinants of PNS regeneration and successful end-organ reinnervation were unveiled. Such knowledge provides cues for designing novel strategies for treating and rehabilitating traumatic PNS damage...
2013: International Review of Neurobiology
Alvaro Campero, Pablo Ajler, Mariano Socolovsky, Carolina Martins, Albert Rhoton
BACKGROUND: Hypoglossal-facial anastomosis is the gold standard treatment for facial reanimation in those cases where the facial nerve has been damaged near the brainstem. The technique that requires temporal bone drilling and partial section of the hypoglossal nerve is usually preferred. This technique diminishes tongue morbidity while preserves good facial reanimation. The goal of the present work is to describe a simple technique to expose the mastoid portion of the facial nerve. METHODS: The mastoid portion of the facial nerve runs on the anterior wall of the mastoid process; mean 18+/-3 mm deeply to the lateral wall...
2012: Surgical Neurology International
Francis Wattel, François Dubois
In France, acute life-threatening situations are handled by the French Secours a Personne (assistance to persons) and emergency medical facilities. An unequivocal success, this early management of life-threatening emergency situations relies upon centralized call reception, medical dispatching, and immediate on-site emergency medical care. We describe the different emergency care providers and steps involved in the response to emergency situations. Each call centre (Samu, phone number 15; Sapeurs-Pompiers, 18) provides a response tailored to the nature of incoming calls for assistance...
April 2012: Bulletin de L'Académie Nationale de Médecine
Margaret Coyle, Andrew Godden, Peter A Brennan, Luke Cascarini, Darryl Coombes, Cyrus Kerawala, James McCaul, Daryl Godden
Facial paralysis can have a profound effect on the patient from both an aesthetic and functional point of view. The symptoms depend on which branch of the nerve has been damaged and the severity of the injury. The purpose of this paper is to review currently available treatments for dynamic reanimation of a damaged facial nerve, and the goals are a symmetrical and coordinated smile. Careful selection of patients and use of the appropriate surgical technique can have excellent results.
December 2013: British Journal of Oral & Maxillofacial Surgery
Sang Hyun Lim, Sungsoo Lee, Kentaro Noda, Tomohiro Kawamura, Yugo Tanaka, Norihisa Shigemura, Atsunori Nakao, Yoshiya Toyoda
OBJECTIVES: Advanced donor age is one of the risk factors for graft failure and is the leading cause of early death after heart transplantation. Better myocardial preservation methods should reduce graft failure. The purpose of this study was to determine if adenosine, which is known to enhance cardioplegic protection, enhances myocardial preservation during heart transplantation using older donors. METHODS: We used a rat heterotopic heart transplantation model with Lewis rats that were at least 60 weeks old as donors...
June 2013: European Journal of Cardio-thoracic Surgery
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