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https://www.readbyqxmd.com/read/29780690/an-update-on-the-treatment-of-pediatric-autoimmune-encephalitis
#1
Cory Stingl, Kathleen Cardinale, Heather Van Mater
Purpose of review: Autoimmune encephalitis (AE) is an increasingly recognized etiology for neuropsychiatric deficits that are highly responsive to immunotherapy. As a result, rheumatologists are often called upon to help with the diagnosis and treatment of these conditions. The purpose of this review is to provide an update on the pharmacologic treatment of AE. Recent findings: To date, there are no prospective randomized placebo-controlled trials to guide treatment recommendations for AE...
March 2018: Current Treatment Options in Rheumatology
https://www.readbyqxmd.com/read/29769121/anxiety-and-depression-in-primary-sj%C3%A3-gren-s-syndrome-a-cross-sectional-study
#2
Yafei Cui, Ling Xia, Lin Li, Qian Zhao, Shengnan Chen, Zhifeng Gu
BACKGROUND: Prevalence of anxiety and depression is high in people with Primary Sjögren's syndrome (pSS). However, there are currently no known reported studies about anxiety/depression in pSS patients from China. Our aim was to compare anxiety/depression in pSS patients and healthy controls; to investigate the prevalence of anxiety and/or depression among pSS patients in China; to evaluate its relationship with the disease activity, fatigue, pain, education, ocular surface disease, oral health, swallowing disorders, employment status, European League Against Rheumatism Sjögren's Syndrome Patient Reported Index(ESSPRI) as well as to analyze potential determinants of anxiety and depression...
May 16, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29766250/juvenile-idiopathic-arthritis-the-role-of-imaging-from-a-rheumatologist-s-perspective
#3
REVIEW
Clara Malattia, Nikolay Tzaribachev, J Merlijn van den Berg, Silvia Magni-Manzoni
Alongside recent advances in treatment strategies for juvenile idiopathic arthritis (JIA), paediatric rheumatologists have taken increasing interest in the use of imaging. Magnetic resonance imaging (MRI) and musculoskeletal ultrasound, by providing more detailed information on disease activity than clinical examination and conventional radiography (CR), have become helpful diagnostic and managerial tools. The growing skeleton, however, with changing appearances over time, is still challenging in the establishment of valid scoring systems for pathological changes...
June 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29757802/assessing-unwanted-variations-in-rheumatology-clinic-previsit-rooming
#4
Edmond Ramly, Brad Stroik, Diane R Lauver, Heather M Johnson, Patrick McBride, Kristin Steffen Lewicki, Jon Arnason, Christie M Bartels
BACKGROUND: Rheumatologists face time pressures similar to primary care but have not generally benefitted from optimized team-based rooming during the time from the waiting room until the rheumatologist enters the room. OBJECTIVE: The aim of this study was to assess current capacity for population management in rheumatology clinics; we aimed to measure the tasks performed by rheumatology clinic staff (medical assistants or nurses) during rooming. METHODS: We performed a cross-sectional time-study and work-system analysis to measure rooming workflows at 3 rheumatology clinics in an academic multispecialty practice during 2014-2015...
May 11, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29757414/vaccination-coverage-in-systemic-lupus-erythematosus-a-cross-sectional-analysis-of-the-german-long-term-study-lula-cohort
#5
Gamal Chehab, Jutta G Richter, Ralph Brinks, Rebecca Fischer-Betz, Borgi Winkler-Rohlfing, Matthias Schneider
Objectives: Vaccinations are an important measure to prevent infections in immunocompromised patients. The knowledge of vaccination coverage and reasons for non-vaccination in patients with SLE is scarce. The aim of this study was to assess coverage rates of selected vaccinations in a representative sample of SLE patients and to identify predictors for non-vaccination. Methods: In 2013, information on selected vaccinations (coverage, application and reservations) and on demographics, clinical parameters and health beliefs was assessed by means of a self-reported questionnaire among a representative sample of SLE patients in Germany (LuLa cohort)...
May 10, 2018: Rheumatology
https://www.readbyqxmd.com/read/29755898/an-unusual-presentation-of-kikuchi-fujimoto-disease-with-recurrent-subdural-effusion
#6
Sara Shahid, Syed H Alam, Indira Hadley
A 24-year-old man complained of a right temporal headache for four weeks. The patient denied any trauma or previous anticoagulation use. He also reported tender right facial swelling. His physical exam was unrevealing except for right cranial nerve (CN) VI palsy, right parotid enlargement, and cervical adenopathy. Laboratory findings were significant for mild leukopenia at 3300 cells/uL. The computed tomography (CT) scan obtained showed a chronic left subdural effusion with a 4 mm midline shift and confirmed right parotid enlargement and cervical lymphadenopathy...
March 10, 2018: Curēus
https://www.readbyqxmd.com/read/29754192/gastrointestinal-disorders-associated-with-primary-immunodeficiency-diseases
#7
REVIEW
Stella Hartono, Michelina Rosa Ippoliti, Maria Mastroianni, Ricardo Torres, Nicholas L Rider
There are now 354 inborn errors of immunity (primary immunodeficiency diseases (PIDDs)) with 344 distinct molecular etiologies reported according to the International Union of Immunological Sciences (IUIS) (Clin Gastroenterol Hepatol 11: p. 1050-63, 2013, Semin Gastrointest Dis 8: p. 22-32, 1997, J Clin Immunol 38: p. 96-128, 2018). Using the IUIS document as a reference and cross-checking PubMed ( www.ncbi.nlm.nih.pubmed.gov ), we found that approximately one third of the 354 diseases of impaired immunity have a gastrointestinal component [J Clin Immunol 38: p...
May 13, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29735288/clinical-practice-guidelines-for-the-treatment-of-systemic-lupus-erythematosus-by-the-mexican-college-of-rheumatology
#8
Daniel Xibillé-Friedmann, Marcela Pérez-Rodríguez, Sandra Carrillo-Vázquez, Everardo Álvarez-Hernández, Francisco Javier Aceves, Mario C Ocampo-Torres, Conrado García-García, José Luis García-Figueroa, Javier Merayo-Chalico, Ana Barrera-Vargas, Margarita Portela-Hernández, Sandra Sicsik, Lilia Andrade-Ortega, Víctor Manuel Rosales-Don Pablo, Aline Martínez, Pilar Prieto-Seyffert, Mario Pérez-Cristóbal, Miguel Ángel Saavedra, Zully Castro-Colín, Azucena Ramos, Gabriela Huerta-Sil, María Fernanda Hernández-Cabrera, Luis Javier Jara, Leonardo Limón-Camacho, Lizbet Tinajero-Nieto, Leonor A Barile-Fabris
There are national and international clinical practice guidelines for systemic lupus erythematosus treatment. Nonetheless, most of them are not designed for the Mexican population or are devoted only to the treatment of certain disease manifestations, like lupus nephritis, or are designed for some physiological state like pregnancy. The Mexican College of Rheumatology aimed to create clinical practice guidelines that included the majority of the manifestations of systemic lupus erythematosus, and also incorporated guidelines in controversial situations like vaccination and the perioperative period...
May 4, 2018: Reumatología Clinica
https://www.readbyqxmd.com/read/29730684/ultrasonography-of-the-nail-unit-reveals-quantitative-and-qualitative-alterations-in-patients-with-psoriasis-and-psoriatic-arthritis
#9
Luca Idolazzi, Paolo Gisondi, Angelo Fassio, Ombretta Viapiana, Alessandro Giollo, Maurizio Rossini, Giampiero Girolomoni, Davide Gatti
AIMS: The nail unit is a matter of interest both for dermatologist and rheumatologist. The nail is considered one of the possible targets of assessment, especially when ultrasonography is performed. The aim of the study is to highlight peculiar features and alterations of the nail unit in patients affected by psoriasis and psoriatic arthritis versus healthy controls using ultrasonography. MATERIALS AND METHODS: The study sample included 82 patients affected by psoriasis and/or psoriatic arthritis and 50 healthy controls...
May 2, 2018: Medical Ultrasonography
https://www.readbyqxmd.com/read/29728839/development-of-minimum-standards-of-care-for-juvenile-localized-scleroderma
#10
REVIEW
Tamás Constantin, Ivan Foeldvari, Clare E Pain, Annamária Pálinkás, Peter Höger, Monika Moll, Dana Nemkova, Lisa Weibel, Melinda Laczkovszki, Philip Clements, Kathryn S Torok
Juvenile localized scleroderma (jLS), also known as morphea, is an orphan disease. Pediatric guidelines regarding diagnosis, assessment, and management are lacking.Our objective was to develop minimum standards of care for diagnosis, assessment, and management of jLS. A systematic review was undertaken to establish the pediatric evidence for assessment and monitoring of jLS. An expert panel, including members of the Pediatric Rheumatology European Society (PRES) Scleroderma Working Group, were invited to a consensus meeting where recommendations were developed based on evidence graded by the systematic review and, where evidence was lacking, consensus opinion...
May 4, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29722248/standardized-musculoskeletal-ultrasonographic-reference-values-for-healthy-korean-adults
#11
Hyun-Sook Kim, Hae-Rim Kim, Bo Young Kim, Yun Sung Kim, Young Ok Jung, Sung Jae Choi, Hyun-Ok Kim, Jiwon Hwang, Sunggun Lee, Hyoun-Ah Kim, So Young Bang, Ji-Young Chai, Sung-Hoon Park, Chong-Hyeon Yoon
Background/Aims: To define standard reference values for musculoskeletal ultrasonography (MSUS) in Korea. Methods: A total of 251 healthy adults were recruited for this study. Ultrasonography was performed by experienced rheumatologists who had undergone four appropriate training programs in Korea. A General Electric LOGIQ electronic ultrasound device fitted with a 12 MHz linear transducer was employed. Mean values ± standard deviations (SDs) were defined as standard reference values...
May 4, 2018: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29721712/a-retrospective-analysis-of-medication-prescription-records-for-determining-the-levels-of-compliance-and-persistence-to-urate-lowering-therapy-for-the-treatment-of-gout-and-hyperuricemia-in-the-netherlands
#12
C A Janssen, M A H Oude Voshaar, H E Vonkeman, M Krol, M A F J van de Laar
Urate-lowering therapy (ULT) is a recommended life-long treatment for gout patients. However, despite these recommendations, recurrent gout attacks are commonly observed in clinical practice. The purpose of this study was to assess the levels of compliance and persistence to ULT in The Netherlands, in order to reflect on the current gout care delivered by health professionals. Anonymous prescription records were obtained from IQVIA's Dutch retrospective longitudinal prescription database, containing ULT dispensing data for allopurinol, febuxostat, and benzbromarone from November 2013 to July 2017...
May 2, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29720509/state-of-the-art-in-interstitial-pneumonia-with-autoimmune-features-a-systematic-review-on-retrospective-studies-and-suggestions-for-further-advances
#13
REVIEW
Gianluca Sambataro, Domenico Sambataro, Sebastiano Emanuele Torrisi, Ada Vancheri, Mauro Pavone, Roberta Rosso, Matteo Schisano, Claudia Crimi, Francesca Pignataro, Aryeh Fischer, Nicoletta Del Papa, Carlo Vancheri
The term interstitial pneumonia with autoimmune features (IPAF) has been proposed to define patients with interstitial lung disease (ILD) associated with autoimmune signs not classifiable for connective tissue diseases (CTDs). This new definition overcomes previous nomenclatures and provides a uniform structure for prospective studies through specific classification criteria.This work evaluates the characteristics of IPAF patients reported in the literature, to highlight potential limits through a comparative analysis and to suggest better performing classification criteria...
June 30, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29718851/ultrasound-b-lines-in-the-evaluation-of-interstitial-lung-disease-in-patients-with-systemic-sclerosis-cut-off-point-definition-for-the-presence-of-significant-pulmonary-fibrosis
#14
Marika Tardella, Marco Di Carlo, Marina Carotti, Emilio Filippucci, Walter Grassi, Fausto Salaffi
The aim of this study was to establish the cut-off point of ultrasound (US) B-lines number for detecting the presence of significant interstitial lung disease (ILD) in patients with systemic sclerosis (SSc) (SSc-ILD) in relation to high-resolution computed tomography (HRCT) findings.Consecutive SSc-ILD patients underwent chest HRCT, lung US (LUS), pulmonary function test, and clinical assessment. Exclusion criteria were represented by the presence of a coexisting congestive heart failure and a clinical history suggestive of lung or pleural diseases...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29697850/depressive-symptoms-pain-and-disability-for-adolescent-patients-with-juvenile-idiopathic-arthritis-results-from-the-childhood-arthritis-prospective-study
#15
Laura Hanns, Lis Cordingley, James Galloway, Sam Norton, Livia A Carvalho, Deborah Christie, Debajit Sen, Roberto Carrasco, Amir Rashid, Helen Foster, Eileen Baildam, Alice Chieng, Joyce Davidson, Lucy R Wedderburn, Kimme Hyrich, Wendy Thomson, Yiannis Ioannou
Objectives: To determine if depressive symptoms assessed near diagnosis associate with future measures of pain, disability and disease for adolescent patients diagnosed with JIA. Methods: Data were analysed from JIA patients aged 11-16 years recruited to the Childhood Arthritis Prospective Study, a UK-based inception cohort of childhood-onset arthritis. Depressive symptoms (using the Mood and Feelings Questionnaire; MFQ), active and limited joint count, disability score (Childhood Health Assessment Questionnaire), pain visual analogue scale and patient's general evaluation visual analogue scale were collected...
April 25, 2018: Rheumatology
https://www.readbyqxmd.com/read/29691685/adherence-and-health-literacy-as-related-to-outcome-of-patients-treated-for-rheumatoid-arthritis-analyses-of-a-large-scale-observational-study
#16
J G Kuipers, M Koller, F Zeman, K Müller, J U Rüffer
BACKGROUND: Disabilities in daily living and quality of life are key endpoints for evaluating the treatment outcome for rheumatoid arthritis (RA). Factors possibly contributing to good outcome are adherence and health literacy. METHODS: The survey included a representative nationwide sample of German rheumatologists and their patients with RA. The physician questionnaire included the disease activity score (DAS28) and medical prescriptions. The patient questionnaire included fatigue (EORTC QLQ-FA13), health assessment questionnaire (HAQ), quality of life (SF-12), health literacy (HELP), and patients' listings of their medications...
April 24, 2018: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29688532/a-novel-lupus-activity-index-accounting-for-glucocorticoids-sledai-2k-glucocorticoid-index
#17
Zahi Touma, Dafna D Gladman, Jiandong Su, Nicole Anderson, Murray B Urowitz
Objective: To develop and validate a modification of SLEDAI-2K to accurately describe disease activity while accounting for glucocorticoid (GC) doses. Methods: The first two phases focused on the development of the index. Phase 1: identification of scenarios of real patients seen prospectively in a longitudinal cohort. Phase 2: derivation of an equation that explains the association between SLEDAI-2K and GC doses using physician global assessment as the external construct...
April 20, 2018: Rheumatology
https://www.readbyqxmd.com/read/29686439/clinical-pattern-of-systemic-sclerosis-in-central-ukraine-association-between-clinical-manifestations-of-systemic-sclerosis-and-hypertension
#18
Viktor Semenov, Olexandr Kuryata, Tatiana Lysunets
Objectives: Systemic sclerosis (SSc) is a rare disease of connective tissue, manifestations of which may vary in different geographical areas. We aimed to describe the clinical portrait of patients with SSc in Dnipropetrovsk region and to investigate how initial clinical and laboratory characteristics are connected with the presence of hypertension in SSc onset. Material and methods: Patients were enrolled to this study from the registry of SSc patients, established in the Rheumatology Department, Mechnikov Dnipropetrovsk Regional Clinic, Dnipro...
2018: Reumatologia
https://www.readbyqxmd.com/read/29686436/methotrexate-treatment-for-rheumatoid-arthritis-in-poland-retrospective-analysis-of-patients-in-routine-clinical-practice
#19
Jerzy Świerkot, Bogdan Batko, Piotr Wiland, Mariusz Jędrzejewski, Marcin Stajszczyk
Objectives: The aim of this study was to evaluate methotrexate (MTX) treatment administered by Polish rheumatologists in everyday practice. Material and methods: The study was based on a retrospective analysis of a cohort of 1957 patients with rheumatoid arthritis (RA). It was conducted among 100 rheumatologists, each of whom received 20 questionnaires and completed them based on the data from their rheumatoid arthritis patients. Results: Methotrexate was taken by 91% of patients, and 80% of them continued the treatment either as a monotherapy (65%) or concomitantly with other disease-modifying anti-rheumatic drugs...
2018: Reumatologia
https://www.readbyqxmd.com/read/29672808/anterior-chest-wall-in-axial-spondyloarthritis-imaging-interpretation-and-differential-diagnosis
#20
Winston J Rennie, Lennart Jans, Anne Grethe Jurik, Iwona Sudoł-Szopińska, Claudia Schueller-Weidekamm, Iris Eshed
Anterior chest wall (ACW) inflammation is not an uncommon finding in patients with axial spondyloarthritis (ax-SpA) and reportedly occurs in 26% of these patients. Radiologists may only be familiar with spinal and peripheral joint imaging, possibly due to the inherent challenges of ACW imaging on some cross-sectional imaging modalities. Knowledge of relevant joint anatomy and the location of sites of inflammation allows the interpreting radiologist to better plan appropriate imaging tests and imaging planes...
April 2018: Seminars in Musculoskeletal Radiology
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