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Nerve graft

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https://www.readbyqxmd.com/read/28738725/seeding-nerve-sutures-with-minced-nerve-graft-mine-g-a-simple-method-to-improve-nerve-regeneration-in-rats
#1
Salvatore D'Arpa, Giovanni Zabbia, Carla Cannizzaro, Grazia Salimbeni, Fulvio Plescia, Alessio Vincenzo Mariolo, Giovanni Cassata, Luca Cicero, Roberto Puleio, Anna Martorana, Francesco Moschella, Adriana Cordova
BACKGROUND: The aim of this study was to assess the effect of seeding the distal nerve suture with nerve fragments in rats. METHODS: On 20 rats, a 15 mm sciatic nerve defect was reconstructed with a nerve autograft. In the Study Group (10 rats), a minced 1 mm nerve segment was seeded around the nerve suture. In the Control Group (10 rats), a nerve graft alone was used. At 4 and 12 weeks, a walking track analysis with open field test (WTA), hystomorphometry (number of myelinated fibers (n), fiber density (FD) and fiber area (FA) and soleus and gastrocnemius muscle weight ratios (MWR) were evaluated...
July 25, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28736354/novel-technique-of-percutaneous-fat-graft-for-repair-of-persistent-large-pseudomeningocele
#2
Gabrielle Santangelo, Tyler Schmidt, Mithra Gonzalez, Per-Lennart Westesson, Howard Silberstein
BACKGROUND: Pseudomeningocele is an uncommon but problematic complication in lumbar spine surgery. Initial conservative measures are frequently successful but persistence requires additional management. The current surgical approach can involve a range of techniques, including blood patches, hydrogel/fibrin sealants, drains, open surgical repair of the dura or a combination of the above if symptoms persist. This report demonstrates a novel technique for repair using a percutaneous approach to deliver an autologous fat graft into the pseudomeningocele...
July 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28724864/anatomic-and-histological-study-of-lingual-nerve-and-its-clinical-implications
#3
Yoshiaki Shimoo, Masahito Yamamoto, Masashi Suzuki, Masato Yamauchi, Akihiro Kaketa, Masaaki Kasahara, Masamitsu Serikawa, Kei Kitamura, Satoru Matsunaga, Shinichi Abe
Although the risk of injuring the lingual nerve in the mandibular molar area during dental treatment is high, it can be repaired by nerve grafting. However, from the perspective of clinical dentistry, the pathway and histomorphometric characteristics of this nerve remain to be documented in detail. The purpose of the present study was to morphologically elucidate the pathway of the lingual nerve to clarify its significance in a clinical setting. A histomorphometric analysis was also performed in consideration of nerve grafting...
2017: Bulletin of Tokyo Dental College
https://www.readbyqxmd.com/read/28723757/comprehensive-comparing-percutaneous-endoscopic-lumbar-discectomy-with-posterior-lumbar-internal-fixation-for-treatment-of-adjacent-segment-lumbar-disc-prolapse-with-stable-retrolisthesis-a-retrospective-case-control-study
#4
Yapeng Sun, Wei Zhang, Suhui Qie, Nan Zhang, Wenyuan Ding, Yong Shen
The study was to comprehensively compare the postoperative outcome and imaging parameter characters in a short/middle period between the percutaneous endoscopic lumbar discectomy (PELD) and the internal fixation of bone graft fusion (the most common form is posterior lumbar interbody fusion [PLIF]) for the treatment of adjacent segment lumbar disc prolapse with stable retrolisthesis after a previous lumbar internal fixation surgery.In this retrospective case-control study, we collected the medical records from 11 patients who received PELD operation (defined as PELD group) for and from 13 patients who received the internal fixation of bone graft fusion of lumbar posterior vertebral lamina decompression (defined as control group) for the treatment of the lumbar disc prolapse combined with stable retrolisthesis at Department of Spine Surgery, the Third Hospital of Hebei Medical University (Shijiazhuang, China) from May 2010 to December 2015...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28720074/regeneration-of-long-distance-peripheral-nerve-defects-after-delayed-reconstruction-in-healthy-and-diabetic-rats-is-supported-by-immunomodulatory-chitosan-nerve-guides
#5
Lena Stenberg, Maria Stößel, Giulia Ronchi, Stefano Geuna, Yaobin Yin, Susanne Mommert, Lisa Mårtensson, Jennifer Metzen, Claudia Grothe, Lars B Dahlin, Kirsten Haastert-Talini
BACKGROUND: Delayed reconstruction of transection or laceration injuries of peripheral nerves is inflicted by a reduced regeneration capacity. Diabetic conditions, more frequently encountered in clinical practice, are known to further impair regeneration in peripheral nerves. Chitosan nerve guides (CNGs) have recently been introduced as a new generation of medical devices for immediate peripheral nerve reconstruction. Here, CNGs were used for 45 days delayed reconstruction of critical length 15 mm rat sciatic nerve defects in either healthy Wistar rats or diabetic Goto-Kakizaki rats; the latter resembling type 2 diabetes...
July 18, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28720003/current-trends-in-the-management-of-ballistic-fractures-of-the-hand-and-wrist-experiences-of-a-high-volume-level-i-trauma-center
#6
Paul A Ghareeb, Charles Daly, Albert Liao, Diane Payne
BACKGROUND: Ballistic fractures of the carpus and hand are routinely treated in large urban centers. These injuries can be challenging due to many factors. Various treatment options exist for these complicated injuries, but there are limited data available. This report analyzes patient demographics, treatments, and outcomes at a large urban trauma center. METHODS: All ballistic fractures of the hand and wrist of the patients who presented to a single center from 2011 to 2014 were retrospectively reviewed...
March 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28719556/inadvertent-harvest-of-the-median-nerve-instead-of-the-palmaris-longus-tendon
#7
Bruce M Leslie, A Lee Osterman, Scott W Wolfe
BACKGROUND: The palmaris longus tendon is frequently used as a tendon graft or ligament replacement. In rare instances the median nerve has been inadvertently harvested instead of the palmaris longus for use as a tendon. METHODS: Nineteen cases in which the median nerve had been mistakenly harvested instead of the palmaris longus tendon were collected from members of the American Society for Surgery of the Hand (ASSH) Listserve. Surgeons involved in the subsequent care of the subject who had had an inadvertent harvest were contacted or the chart was reviewed...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28709584/first-sacral-nerve-and-anterior-longitudinal-ligament-anatomy-clinical-applications-during-sacrocolpopexy
#8
Maria E Florian-Rodriguez, Jennifer Hamner, Marlene M Corton
BACKGROUND: The recommended location of graft attachment during sacrocolpopexy is at or below the sacral promontory on the anterior surface of the first sacral vertebra. Graft fixation below the sacral promontory may potentially involve the first sacral nerve. OBJECTIVES: The objectives of this study were to examine the anatomy of the right first sacral nerve relative to the midpoint of the sacral promontory and to evaluate the thickness and ultrastructural composition of the anterior longitudinal ligament at the sacral promontory level...
July 11, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28703910/medialis-pedis-flap-for-reconstruction-of-weight-bearing-heel
#9
Jin Sung Park, Jae Hoon Lee, Jung Suk Lee, Jong Hun Baek
BACKGROUND: Among the various flaps available for the reconstruction of the heel, a medial plantar flap has been widely accepted as the most ideal. This flap, however, involves the medial plantar nerve and its cutaneous branches, which may lead to postoperative hyperesthesia and dual sensation. The purpose of this report was to report the outcomes of the use of the medialis pedis flap for the coverage of weight bearing heel soft tissue defect. PATIENTS AND METHODS: A total of 8 patients who had undergone reconstruction of the weight bearing heel with the medialis pedis flap were enrolled for this study...
July 13, 2017: Microsurgery
https://www.readbyqxmd.com/read/28697631/recent-advances-on-biomedical-applications-of-scaffolds-in-wound-healing-and-dermal-tissue-engineering
#10
Azizeh Rahmani Del Bakhshayesh, Nasim Annabi, Rovshan Khalilov, Abolfazl Akbarzadeh, Mohammad Samiei, Effat Alizadeh, Mohammadreza Alizadeh-Ghodsi, Soodabeh Davaran, Azadeh Montaseri
The tissue engineering field has developed in response to the shortcomings related to the replacement of the tissues lost to disease or trauma: donor tissue rejection, chronic inflammation and donor tissue shortages. The driving force behind the tissue engineering is to avoid the mentioned issues by creating the biological substitutes capable of replacing the damaged tissue. This is done by combining the scaffolds, cells and signals in order to create the living, physiological, three-dimensional tissues. A wide variety of skin substitutes are used in the treatment of full-thickness injuries...
July 12, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28694597/management-of-cervical-monoradiculopathy-due-to-prolapsed-intervertebral-disc-an-institutional-experience
#11
Amresh S Bhaganagare, S A Nagesh, B G Shrihari, Vikas Naik, M N Nagarjun, Balaji S Pai
BACKGROUND: Cervical radiculopathy is the common clinical entity, often caused by "wear and tear" changes that occur in the spine. In the younger population, cervical radiculopathy is a result of a disc herniation or an acute injury causing foraminal impingement of an exiting nerve, whereas in the older individuals, it is due to foraminal narrowing from osteophyte formation, decreased disc height, and degenerative changes of the uncovertebral joints anteriorly and of the facet joints posteriorly...
April 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/28694091/combined-intranasal-nerve-growth-factor-and-ventricle-neural-stem-cell-grafts-prolong-survival-and-improve-disease-outcome-in-amyotrophic-lateral-sclerosis-transgenic-mice
#12
Shi-Jiang Zhong, Yan-Hua Gong, Yan-Chen Lin
Amyotrophic lateral sclerosis (ALS) is a fatal disease that selectively involves motor neurons. Neurotrophic factor supplementation and neural stem cell (NSC) alternative therapy have been used to treat ALS. The two approaches can affect each other in their pathways of action, and there is a possibility for synergism. However, to date, there have been no studies demonstrating the effects of combined therapy in the treatment of ALS. In this study, for the first time, we adopted a method involving the intranasal administration of nerve growth factor combined with lateral ventricle NSC transplantation using G93A-SOD1 transgenic mice as experimental subjects to explore the treatment effect of this combined therapy in ALS...
July 8, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28688935/indirect-transfer-of-the-sternal-head-of-the-pectoralis-major-with-autogenous-semitendinosus-augmentation-to-treat-scapular-winging-secondary-to-long-thoracic-nerve-palsy
#13
Tao Li, Ze Z Yang, Yuan Deng, Ming Xiao, Chuan Jiang, Jin W Wang
BACKGROUND: Scapular winging resulting from long thoracic nerve palsy is uncommon but debilitating, and the choice of surgical treatment is inconsistent. The autogenous semitendinosus tendon plays a key role as an interposed tendon graft, although its use in the indirect transfer of the sternal head of the pectoralis major during the treatment of scapular winging has rarely been reported. MATERIALS AND METHODS: A retrospective review was performed during a 9-year period from the clinical data of 26 cases (28 shoulders) with indirect transfer of the sternal head of the pectoralis major with the interposition of an autogenous semitendinosus tendon graft for dynamic stabilization of the scapula...
July 5, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28684285/a-higher-quality-of-life-with-cross-face-nerve-grafting-as-an-adjunct-to-a-hypoglossal-facial-nerve-jump-graft-in-facial-palsy-treatment
#14
Martinus M van Veen, Pieter U Dijkstra, Paul M N Werker
Nerve reconstructions are the preferred technique for short-standing facial paralysis, most commonly using the contralateral facial nerve or ipsilateral hypoglossal nerve. The hypoglossal nerve provides a strong motor signal, whereas the signal of a cross-face nerve graft is weaker but spontaneous. Spontaneity in facial expression is believed to be important for psychological wellbeing. Therefore, a combination of the two procedures incorporates the best of both: a strong motor signal and a spontaneous smile...
June 10, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28678580/reconstructive-subperiosteal-midface-lift-a-three-nonvisible-incision-approach
#15
Marco Sales-Sanz, Constanza Barrancos, Hae-Ryung Won-Kim, Andrea Sales-Sanz, César Colmenero
This article describes our surgical technique for subperiosteal midface elevation in patients with paralytic lower eyelid malposition or cicatricial inferior eyelid retraction. Nineteen patients with paralytic lower eyelid malposition and 15 patients with cicatricial inferior eyelid retraction underwent a subperiosteal midface lift (n = 34). The procedure was performed under local anesthesia through three nonvisible incisions. A transconjunctival incision allows preseptal dissection to the orbital rim, followed by a subperiosteal dissection of the midface...
July 5, 2017: Orbit
https://www.readbyqxmd.com/read/28673630/peripheral-nerve-defects-overviews-of-practice-in-europe
#16
REVIEW
Bruno Battiston, Paolo Titolo, Davide Ciclamini, Bernardino Panero
Many surgical techniques are available for the repair of peripheral nerve defects. Autologous nerve grafts are the gold standard for most clinical conditions. In selected cases, alternative types of reconstructions are performed to fill the nerve gap. Non-nervous autologous tissue-based conduits or synthetic ones are alternatives to nerve autografts. Allografts represent another new field of interest. Decision making in the treatment of nerve defects is based on timing of referral, level of the injury, type of lesion, and size of any gap...
August 2017: Hand Clinics
https://www.readbyqxmd.com/read/28669300/contralateral-c-7-transfer-is-direct-repair-really-superior-to-grafting
#17
Anil Bhatia, Piyush Doshi, Ashok Koul, Vitrag Shah, Justin M Brown, Mahmoud Salama
It is not uncommon for a severe traumatic brachial plexus injury to involve all 5 roots, resulting in a flail upper limb. In such cases, surgical reconstruction is often palliative, providing only rudimentary function. Nerve transfers are the mainstay of reconstructive strategies due to the predominance of root avulsions. Consistent results are obtained only for restoration of shoulder stability and elbow flexion, whereas restoring useful hand function remains a challenge. The transfer of the contralateral C-7 (cC-7) is commonly used in an attempt to restore basic hand function, but results are notoriously unreliable and inconsistent...
July 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28669295/nerve-transfer-versus-muscle-transfer-to-restore-elbow-flexion-after-pan-brachial-plexus-injury-a-cost-effectiveness-analysis
#18
Arvin R Wali, David R Santiago-Dieppa, Justin M Brown, Ross Mandeville
OBJECTIVE Pan-brachial plexus injury (PBPI), involving C5-T1, disproportionately affects young males, causing lifelong disability and decreased quality of life. The restoration of elbow flexion remains a surgical priority for these patients. Within the first 6 months of injury, transfer of spinal accessory nerve (SAN) fascicles via a sural nerve graft or intercostal nerve (ICN) fascicles to the musculocutaneous nerve can restore elbow flexion. Beyond 1 year, free-functioning muscle transplantation (FFMT) of the gracilis muscle can be used to restore elbow flexion...
July 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28661982/extra-articular-soft-tissue-calcification-after-burn-injury-a-case-study
#19
Young Jae Moon, Seong-Yup Jeong, Kwang-Bok Lee
Soft-tissue calcifications after burn injury commonly develop in periarticular regions, especially in the elbow joint. They can be easily recognized in patients because calcification in the joint limits range of motion and brings about tingling sensation due to compression of ulnar nerve. However, the incidence of extra-articular soft-tissue calcification after burn injury has rarely been reported. We present a patient with massive soft-tissue calcification in extra-articular burn scar with nonhealing ulcer after a long latency period of 40 years...
June 28, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28657487/delayed-spinal-cord-brachial-plexus-reconnection-after-c7-ventral-root-avulsion-the-effect-of-reinnervating-motoneurons-rescued-by-riluzole-treatment
#20
Balázs Gloviczki, Dénes G Török, Gábor Márton, László Gál, Tamás Bodzay, Sándor Pintér, Antal Nógrádi
Ventral root avulsion induces dramatic loss of the affected spinal cord motoneurons. The neuroprotective effect of riluzole has been previously proven on the injured motoneurons: the vast majority of them can be rescued even when they have no possibility to regenerate their axons. In this study the number of injured motoneurons rescued by riluzole treatment and their capacity to reinnervate the denervated forelimb muscles was investigated. Surgical reconnection with a peripheral nerve graft between the affected spinal cord segment and the C7 spinal nerve was established immediately or with 1- and 3-week delay after avulsion...
August 1, 2017: Journal of Neurotrauma
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