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https://www.readbyqxmd.com/read/28339965/opioid-prescriptions-by-specialty-in-ohio-2010-2014
#1
Scott G Weiner, Olesya Baker, Ann F Rodgers, Chad Garner, Lewis S Nelson, Peter W Kreiner, Jeremiah D Schuur
Background. : The current US opioid epidemic is attributed to the large volume of prescribed opioids. This study analyzed the contribution of different medical specialties to overall opioids by evaluating the pill counts and morphine milligram equivalents (MMEs) of opioid prescriptions, stratified by provider specialty, and determined temporal trends. Methods. : This was an analysis of the Ohio prescription drug monitoring program database, which captures scheduled medication prescriptions filled in the state as well as prescriber specialty...
March 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28329515/cutaneous-mucinosis-in-a-patient-taking-ustekinumab-for-palmoplantar-psoriasis
#2
Caren Garber, David Rosmarin, Bichchau Nguyen, Mahmoud Goodarzi, Shweta Shinagare, Chad Jessup, Abdulaziz Madani, Shiu-Chung Au, Afnan Hasanain
Discrete papular lichen myxedematosus (DPLM), asubset of localized lichen myxedematosus, is a rarecutaneous mucinosis of unknown etiology. We reporta case of a 57-year-old woman with palmoplantarpsoriasis who developed DPLM 8 weeks after addingustekinumab to a long-term course of methotrexate.The patient had previously failed 2 prior tumor necrosisfactor (TNF) inhibitors, adalimumab and etanercept.This case demonstrates an association between TNFinhibitor and ustekinumab use in a psoriasis patientand localized lichen myxedematosus for the secondtime in the literature...
March 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328166/treatment-of-subchondral-lucencies-in-the-medial-proximal-radius-with-a-bone-screw-in-8-horses
#3
Imma Roquet, J Lane Easter, Richard P C Coomer, Luis J Ezquerra, Chad A Marsh, Steve S Trostle, Elizabeth M Santschi
OBJECTIVE: To describe the results of screw placement through subchondral lucencies (SCL) of the proximal radius in 8 horses. STUDY DESIGN: Retrospective clinical study. ANIMALS: Horses with cubital SCL causing lameness (n=8). METHODS: Medical record review and clinical follow-up. RESULTS: Eight horses with SCL in the proximal radius causing lameness were treated with a screw placed across the lucency...
March 22, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28323693/assessment-of-vertebral-curves-using-the-manual-post-it-technique
#4
Brian P Gladnick, Joseph J Schreiber, Chad R Ishmael, Benjamin T Bjerke-Kroll, Matthew E Cunningham
STUDY DESIGN: A prospective study of a new technique. OBJECTIVE: The aims of this study were to report a manual technique for measuring vertebral curves on digital spine radiographs, and to assess the agreement of this technique with that of digital software for measuring vertebral curves. SUMMARY OF BACKGROUND DATA: Modern picture archiving and communication systems (PACS) typically include software for evaluating radiographic measurements...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28318338/latent-class-profiles-of-anxiety-symptom-trajectories-from-preschool-through-school-age
#5
Sarah J Kertz, Chad Sylvester, Rebecca Tillman, Joan L Luby
Anxiety typically arises early in childhood and decreases during school age. However, little is known about the earlier developmental course of anxiety in preschool, especially in at risk children, posing a clinically important problem. Given that anxiety in youth has a chronic course for some and also predicts later development of other mental health problems, it is important to identify factors early in development that may predict chronic anxiety symptoms. At-risk children (oversampled for depression) and caregivers completed 6 assessment waves beginning at preschool age (between 3-5...
March 20, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28298221/post-operative-opioid-pain-management-patterns-for-patients-who-receive-hip-surgery
#6
Chad E Cook, Daniel I Rhon, Brian D Lewis, Steven Z George
BACKGROUND: Identifying optimal, post-operative opioid management strategies is a priority of health providers and government agencies. At present, there are no studies we are aware of that have formally investigated opioid prescribing patterns for post-operative non-arthroplasty orthopedic conditions such as femoroacetabular impingement, nor has any study investigated the influence of opioid prescription patterns on health care costs and utilization. We aimed to investigate a subgrouping scheme associated with post-operative opioid prescription strategies and measure the subgroups' direct and indirect health care utilization and costs in individuals undergoing non-arthroplasty orthopedic hip surgery...
March 16, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28291419/risk-of-failure-in-pediatric-ventriculoperitoneal-shunts-placed-after-abdominal-surgery
#7
Joshua D Burks, Andrew K Conner, Robert G Briggs, Chad A Glenn, Phillip A Bonney, Ahmed A Cheema, Sixia Chen, Naina L Gross, Timothy B Mapstone
OBJECTIVE Experience has led us to suspect an association between shunt malfunction and recent abdominal surgery, yet information about this potential relationship has not been explored in the literature. The authors compared shunt survival in patients who underwent abdominal surgery to shunt survival in our general pediatric shunt population to determine whether such a relationship exists. METHODS The authors performed a retrospective review of all cases in which pediatric patients underwent ventriculoperitoneal shunt operations at their institution during a 7-year period...
February 17, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28291181/total-hip-arthroplasty-in-patients-with-cerebral-palsy-a-cohort-study-matched-to-patients-with-osteoarthritis
#8
Matthew T Houdek, Chad D Watts, Cody C Wyles, Robert T Trousdale, Todd A Milbrandt, Michael J Taunton
BACKGROUND: The spasticity and increased muscle tone observed in patients with cerebral palsy can lead to hip degeneration, subluxation, and pain. Currently, there is hesitation to perform total hip arthroplasty in patients with cerebral palsy because of fears of early wear and dislocation. The purpose of this study was to review the outcomes of total hip arthroplasty in patients with cerebral palsy and to compare outcomes with those of matched patients with a diagnosis of osteoarthritis...
March 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28288060/the-global-incidence-of-appendicitis-a-systematic-review-of-population-based-studies
#9
Mollie Ferris, Samuel Quan, Belle S Kaplan, Natalie Molodecky, Chad G Ball, Greg W Chernoff, Nij Bhala, Subrata Ghosh, Elijah Dixon, Siew Ng, Gilaad G Kaplan
OBJECTIVE: We compared the incidence of appendicitis or appendectomy across the world and evaluated temporal trends. SUMMARY BACKGROUND DATA: Population-based studies reported the incidence of appendicitis. METHODS: We searched MEDLINE and EMBASE databases for population-based studies reporting the incidence of appendicitis or appendectomy. Time trends were explored using Poisson regression and reported as annual percent change (APC) with 95% confidence intervals (CI)...
March 10, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28277687/subjective-social-status-and-rumination-in-relation-to-anxiety-and-depressive-symptoms-and-psychopathology-among-economically-disadvantaged-latinos-in-primary-care
#10
David C Talavera, Daniel J Paulus, Monica Garza, Melissa Ochoa-Perez, Chad Lemaire, Jeanette Valdivieso, Daniel Bogiaizian, Zuzuky Robles, Jafar Bakhshaie, Kara Manning, Rheeda Walker, Michael Businelle, Michael J Zvolensky
The present investigation examined the interactive effects of subjective social status and rumination in relation to anxiety/depressive symptoms and psychopathology among 276 Latinos (82% female; Mage = 39.2, SD = 11.1; 97.0% reported Spanish as first language) who attended a community-based primary health care clinic. Results indicated that the interaction between rumination and subjective social status was significantly associated with depression (B = -.04, t = -3.52, p < .001, 95% CI [-.06, -.02]), social anxiety (B = -...
March 9, 2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/28275168/clinical-trial-characteristics-and-barriers-to-participant-accrual-the-md-anderson-cancer-center-experience-over-30-years-a-historical-foundation-for-trial-improvement
#11
Chad Tang, Steven I Sherman, Mellanie Price, Jun Weng, Suzanne E Davis, David S Hong, James C Yao, Aman Buzdar, George Wilding, J Jack Lee
Purpose: Slow-accruing clinical trials delay the translation of basic biomedical research, contribute to increasing health care costs, and may prohibit trials from reaching their original goals.Experimental Design: We analyzed a prospectively maintained institutional database that tracks all clinical studies at the MD Anderson Cancer Center (Houston, TX). Inclusion criteria were activated phase I-III trials, maximum projected accrual ≥10 participants, and activation prior to March 25, 2011. The primary outcome was slow accrual, defined as <2 participants per year...
March 15, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28274987/the-university-of-north-carolina-medical-center-pharmacy-resident-leadership-certificate-program
#12
Kayley Lyons, Danielle Griggs, Rachel Lebovic, Mary E Roth, David A South, Chad Hatfield
PURPOSE: The development and implementation of a certificate program for pharmacy residents are described. SUMMARY: University of North Carolina (UNC) Medical Center met the call for increased efforts in the area of pharmacy residency leadership training through the design, implementation, and evaluation of a leadership certificate program. The purpose of the UNC certificate program is to develop leaders who will serve others, improve their communities, and advance the profession...
March 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28268504/hip-segmentation-from-mri-volumes-in-infants-for-ddh-diagnosis-and-treatment-planning
#13
Abhilash Rakkunedeth Hareendranathan, Dornoosh Zonoobi, Myles Mabee, Chad Diederichs, Kumaradevan Punithakumar, Michelle Noga, Jacob L Jaremko
Diagnosis and surgical management of Developmental Dysplasia of the Hip (DDH) relies on physical examination and 2D ultrasound scanning. Magnetic Resonance Imaging (MRI) can be used to complement existing techniques and could be advantageous in treatment planning due to its larger field of view. In this paper we propose a semi-automatic method to segment surface models of the acetabulum from MRI images. The method incorporates clinical knowledge in the form of intensity priors which are integrated into a Random Walker (RW) formulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268075/vaccination-of-active-component-us-military-personnel-against-salmonella-typhi
#14
Chad K Porter, Tia Sorrell, Indrani Mitra, Mark S Riddle
INTRODUCTION: Vaccination against Salmonella Typhi is one of the leading public health interventions reducing the risk of typhoid fever. There are two available licensed vaccines, Vivotif, oral live-attenuated, and Typhim Vi, intramuscular Vi capsular polysaccharide. The US military is a high risk travel population commonly vaccinated for S. Typhi. We describe the use of S. Typhi vaccination in this population and the acute reactogenicity profile of these vaccines. METHODS: Data were obtained from the Defense Medical Surveillance System and vaccination identified between 1998 and 2011 from vaccination codes...
March 3, 2017: Vaccine
https://www.readbyqxmd.com/read/28267213/echocardiography-fails-to-detect-left-ventricular-noncompaction-in-a-cohort-of-patients-with-noncompaction-on-cardiac-magnetic-resonance-imaging
#15
Sachin Diwadkar, Leelakrishna Nallamshetty, Carlos Rojas, Alexia Athienitis, Chris Declue, Chad Cox, Aarti Patel, Sanders H Chae
BACKGROUND: Left ventricular noncompaction (LVNC) is a rare disorder characterized by increased left ventricular trabeculation, deep intertrabecular recesses, and a thin compacted myocardial layer with associated clinical sequelae. Cardiac imaging with echocardiogram and cardiac magnetic resonance (CMRI) can detect variable myocardial morphology including excessive trabeculations. Multiple CMRI and echocardiographic criteria have been offered that attempt to identify LVNC morphology. The aim of this study was to assess the utility of echocardiogram in identifying LVNC in a cohort of patients with LVNC detected on CMRI...
March 7, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28262714/size-resolved-pb-distribution-in-the-athabasca-river-shows-snowmelt-in-the-bituminous-sands-region-an-insignificant-source-of-dissolved-pb
#16
Muhammad Babar Javed, Chad W Cuss, Iain Grant-Weaver, William Shotyk
Lead (Pb) is a metal of special importance because of its long history of commercial and industrial use, global atmospheric contamination accelerated by the use of gasoline additives, and health effects, with children being especially vulnerable. Global atmospheric Pb pollution reached its zenith in the 1970's, but subsequent impacts on freshwater aquatic systems are poorly understood. Employing metal-free sampling and handling protocols, we show that snowmelt from the Athabasca bituminous sands region is an insignificant source of dissolved Pb to the Athabasca River (AR)...
March 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28262440/telomere-length-in-patients-with-pulmonary-fibrosis-associated-with-chronic-lung-allograft-dysfunction-and-post-lung-transplantation-survival
#17
Chad A Newton, Julia Kozlitina, Jefferson R Lines, Vaidehi Kaza, Fernando Torres, Christine Kim Garcia
BACKGROUND: Prior studies have shown that patients with pulmonary fibrosis with mutations in the telomerase genes have a high rate of certain complications after lung transplantation. However, few studies have investigated clinical outcomes based on leukocyte telomere length. METHODS: We conducted an observational cohort study of all patients with pulmonary fibrosis who underwent lung transplantation at a single center between January 1, 2007, and December 31, 2014...
February 4, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28260880/impact-of-comorbid-conditions-in-copd-patients-on-health-care-resource-utilization-and-costs-in-a-predominantly-medicare-population
#18
Phil Schwab, Amol D Dhamane, Sari D Hopson, Chad Moretz, Srinivas Annavarapu, Kate Burslem, Andrew Renda, Shuchita Kaila
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) often have multiple underlying comorbidities, which may lead to increased health care resource utilization (HCRU) and costs. OBJECTIVE: To describe the comorbidity profiles of COPD patients and examine the associations between the presence of comorbidities and HCRU or health care costs. METHODS: A retrospective cohort study utilizing data from a large US national health plan with a predominantly Medicare population was conducted...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28252842/effects-of-transendocardial-stem-cell-injection-on-ventricular-proarrhythmia-in-patients-with-ischemic-cardiomyopathy-results-from-the-poseidon-and-tac-hft-trials
#19
Archana Ramireddy, Chad R Brodt, Adam M Mendizabal, Darcy L DiFede, Chris Healy, Vishal Goyal, Yahya Alansari, James O Coffey, Juan F Viles-Gonzalez, Alan W Heldman, Jeffrey J Goldberger, Robert J Myerburg, Joshua M Hare, Raul D Mitrani
Transendocardial stem cell injection in patients with ischemic cardiomyopathy (ICM) improves left ventricular function and structure but has ill-defined effects on ventricular arrhythmias. We hypothesized that mesenchymal stem cell (MSC) implantation is not proarrhythmic. Post hoc analyses were performed on ambulatory ECGs collected from the POSEIDON and TAC-HFT trials. Eighty-eight subjects (mean age 61 ± 10 years) with ICM (mean EF 32.2% ± 9.8%) received treatment with MSC (n = 48), Placebo (n = 21), or bone marrow mononuclear cells (BMC) (n = 19)...
March 2, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28244413/analysis-of-factors-affecting-successful-clinical-trial-enrollment-in-the-context-of-three-prospective-randomized-controlled-trials
#20
Jennifer K Logan, Chad Tang, Zhongxing Liao, J Jack Lee, John V Heymach, Stephen G Swisher, James W Welsh, Jianjun Zhang, Steven H Lin, Daniel R Gomez
PURPOSE: Challenges can arise when attempting to maximize patient enrollment in clinical trials. There have been limited studies focusing on the barriers to enrollment and the efficacy of alternative study design to improve accrual. We analyzed barriers to clinical trial enrollment, particularly the influence of timing, in context of three prospective, randomized oncology trials where one arm was considered more aggressive than the other. METHODS AND MATERIALS: From June 2011 to March 2015, patients who were enrolled on 3 prospective institutional protocols (an oligometastatic non-small cell lung cancer [NSCLC] trial and 2 proton vs intensity modulated radiation therapy trials in NSCLC and esophageal cancer) were screened for protocol eligibility...
March 15, 2017: International Journal of Radiation Oncology, Biology, Physics
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