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https://www.readbyqxmd.com/read/27896825/is-it-time-to-reconsider-lobectomy-in-low-risk-paediatric-thyroid-cancer
#1
Wouter P Kluijfhout, Jesse D Pasternak, Danielle van der Kaay, Menno R Vriens, Evan J Propst, Jonathan D Wasserman
OBJECTIVE: Current guidelines recommend total thyroidectomy for nearly all children with well-differentiated thyroid cancer (WDTC). These guidelines, however, derive from older data accrued prior to current high-resolution imaging. We speculate that there is a sub-population of children who may be adequately treated with lobectomy. DESIGN: Retrospective analysis of prospectively maintained database. PATIENTS: 73 children with WDTC treated between 2004 and 2015...
November 29, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27870977/longitudinal-treatment-patterns-with-adp-receptor-inhibitors-after-myocardial-infarction-insights-from-the-canadian-observational-antiplatelet-study
#2
Akshay Bagai, Tracy Y Wang, Shaun G Goodman, Harold N Fisher, Robert C Welsh, Jean-Pierre Dery, Xiang Zhang, Yajun E Zhu, Asim N Cheema, Payam Dehghani, Saleem A Kassam, John Ducas, Neil Brass, Hahn Hoe Kim, Anthony Fung, Erick Schampaert, Ata Ur Rehman Quraishi, Shamir R Mehta
BACKGROUND: After myocardial infarction (MI) treated with percutaneous coronary intervention (PCI), guidelines recommend dual antiplatelet therapy (DAPT) with aspirin and an ADP receptor inhibitor (ADPri) for at least 1year. However, whether real-world Canadian practice patterns reflect this recommendation is unknown. METHODS: We studied 2175 MI patients treated with PCI and discharged from 26 Canadian hospitals between 12/2011 and 05/2013 in the Canadian Observational Antiplatelet sTudy (COAPT)...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27835925/response-to-therapy-status-is-an-excellent-predictor-of-pregnancy-associated-structural-disease-progression-in-patients-previously-treated-for-differentiated-thyroid-cancer
#3
Luba Rakhlin, Stephanie Fish, R Michael Tuttle
BACKGROUND: Pregnancy may be associated with an increased risk of recurrence /progression of differentiated thyroid cancer (DTC). However, it is unclear if the impact of pregnancy would differ based on pre-pregnancy response to therapy status. Our objective was to investigate the risk of recurrence /progression of DTC applying the response to therapy assessments to pre-pregnancy status as recommended by the 2015 ATA thyroid cancer guidelines. METHODS: This is a retrospective review of 235 women followed at Memorial Sloan Kettering Cancer Center (MSKCC) for DTC and who had a term pregnancy after initial treatment for DTC between 1997 and 2015...
November 11, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27804016/ultrasonography-scoring-systems-can-rule-out-malignancy-in-cytologically-indeterminate-thyroid-nodules
#4
Giorgio Grani, Livia Lamartina, Valeria Ascoli, Daniela Bosco, Francesco Nardi, Ferdinando D'Ambrosio, Antonello Rubini, Laura Giacomelli, Marco Biffoni, Sebastiano Filetti, Cosimo Durante, Vito Cantisani
PURPOSE: To assess the accuracy and reproducibility of ultrasonography classification systems in characterizing cytologically indeterminate thyroid nodules. METHODS: We retrospectively identified 49 nodules that had been surgically resected owing to features classified as indeterminate according to 2010 Italian Consensus on Thyroid Cytology criteria. Three experienced sonographers independently reviewed original sonographic images of each nodule and classified it using the 2015 American Thyroid Association (ATA) guidelines and the Thyroid Imaging Reporting and Data System (TI-RADS) classification proposed by Korean radiologists; later, images were reviewed jointly to obtain consensus classifications of each nodule...
October 31, 2016: Endocrine
https://www.readbyqxmd.com/read/27758032/temporal-analysis-of-thyroid-cancer-management-in-a-melbourne-tertiary-centre
#5
James C Lee, Paula Chang, Simon Grodski, Meei Yeung, William Johnson, Jonathan Serpell
BACKGROUND: The American Thyroid Association (ATA) management guidelines for thyroid cancer were revised in 2009. The aim of this study was to determine if management of thyroid cancer in our institution has changed in accordance with the introduction of the revised ATA guidelines (ATA(2009) ), and to compare the characteristics and management of thyroid cancer in a Melbourne endocrine surgery unit over a 7-year period. METHODS: All patients treated by the Monash University Endocrine Surgery Unit for thyroid cancer between 2007 and 2013 were divided into two groups - the pre-ATA(2009) group (2007-2010) and the post-ATA(2009) group (2011-2013)...
October 18, 2016: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/27750029/significance-of-size-of-persistent-recurrent-central-nodal-disease-on-surgical-morbidity-and-response-to-therapy-in-reoperative-neck-dissection-for-papillary-thyroid-carcinoma
#6
Brian H Lang, Tony Shek, Angel On-Kei Chan, C Y Lo, Koon Yat Wan
Background To balance the risk of disease progression, morbidity and efficacy of reoperative central neck dissection (RCND) in papillary thyroid carcinoma, the latest clinical guidelines recommend early surgery over surveillance when the largest diseased node is >8 mm in its smallest dimension. However, the evidence remains scarce. To determine an appropriate size for first-time RCND, we examined the relationship between size of largest diseased central node, morbidity and response-to-therapy following RCND...
October 17, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27750028/practical-performance-of-the-2015-american-thyroid-association-guidelines-for-predicting-tumor-recurrence-in-patients-with-papillary-thyroid-cancer-in-south-korea
#7
Seul Gi Lee, Woo Kyung Lee, Hye Sun Lee, Jieun Moon, Cho Rok Lee, Sang Wook Kang, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung, Young Suk Jo, Jandee Lee
BACKGROUND: The 2015 American Thyroid Association (ATA) management guidelines for adult patients with differentiated thyroid cancer propose the use of the modified initial risk stratification and response to therapy re-stratification systems. This study was conducted to validate the practicality of the revised guidelines for predicting tumor recurrence in patients with differentiated thyroid cancer. METHODS: Patients with papillary thyroid cancer (n = 2425) who underwent total thyroidectomy with central neck node dissection with or without modified radical neck node dissection at a single institution between October 1985 and July 2009 were retrospectively enrolled...
November 16, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27717219/comprehensive-management-of-recurrent-thyroid-cancer-an-american-head-and-neck-society-consensus-statement-ahns-consensus-statement
#8
Joseph Scharpf, Michael Tuttle, Richard Wong, Drew Ridge, Russell Smith, Dana Hartl, Robert Levine, Gregory Randolph
This American Head and Neck Society (AHNS) consensus statement focuses on the detection and management of recurrent thyroid cancer. This document describes the radiologic approach to defining structural recurrent disease and the operative and nonoperative rationale in addressing identified structural disease to create equipoise in the personalized treatment strategy for the patient. The recommendations of this AHNS multidisciplinary consensus panel of the American Head and Neck Society are intended to help guide all multidisciplinary clinicians who diagnose or manage adult patients with thyroid cancer...
December 2016: Head & Neck
https://www.readbyqxmd.com/read/27704738/the-revised-2016-korean-thyroid-association-guidelines-for-thyroid-nodules-and-cancers-differences-from-the-2015-american-thyroid-association-guidelines
#9
Ka Hee Yi
Increased detection of thyroid nodules using high-resolution ultrasonography has resulted in a world-wide increase in the incidence of differentiated thyroid cancer (DTC). Despite the steep increase in its incidence, the age-standardized mortality rate of thyroid cancer has remained stable, which leads toward a trend of more conservative treatment. The latest American Thyroid Association (ATA) guidelines for thyroid nodules and thyroid cancer revised in 2015 suggested that fine needle aspiration biopsy should be performed for thyroid nodules larger than 1 cm and lobectomy might be sufficient for 1 to 4 cm intrathyroidal DTC...
September 2016: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27690203/practice-guidelines-for-teledermatology
#10
Karen McKoy, Nina M Antoniotti, April Armstrong, Rashid Bashshur, Jordana Bernard, Daniel Bernstein, Anne Burdick, Karen Edison, Mark Goldyne, Carrie Kovarik, Elizabeth A Krupinski, Joseph Kvedar, Jim Larkey, Ivy Lee-Keltner, Jules B Lipoff, Dennis H Oh, Hon Pak, Mark P Seraly, Daniel Siegel, Trilokraj Tejasvi, John Whited
Previous American Telemedicine Association (ATA) Teledermatology Practice Guidelines were issued in 2007. This updated version reflects new knowledge in the field, new technologies, and the need to incorporate teledermatology practice in a variety of settings, including hospitals, urgent care centers, Federally Qualified Health Centers, school-based clinics, public health facilities, and patient homes.
September 30, 2016: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/27623139/variability-of-serum-thyroglobulin-levels-in-post-thyroidectomy-patients-with-well-differentiated-thyroid-cancer-the-ata-guidelines
#11
Frieda Silva, Ralph J Martin, Jannette Figueroa, Fernando Rincón, Diego Román
OBJECTIVE: Evaluate the variability of stimulated serum thyroglobulin (Tg) levels in post-thyroidectomy patients with well-differentiated thyroid cancer (WDTC) and determine the frequency of undetectable Tg in patients with evidence of functional thyroid tissue after a 131-I whole-body scan (WBS). METHODS: A retrospective record review of patients with WDTC referred to our clinic from 1990 to 2010. Demographic data, histology, staging, imaging studies, stimulated Tg values, and the presence if applicable of Tg antibodies (TgAb) were documented...
September 2016: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/27557846/acknowledging-gray-areas-2015-vs-2009-american-thyroid-association-differentiated-thyroid-cancer-guidelines-on-ablating-putatively-low-intermediate-risk-patients
#12
Savvas Frangos, Ioannis P Iakovou, Robert J Marlowe, Nicolaos Eftychiou, Loukia Patsali, Anna Vanezi, Androulla Savva, Vassilis Mpalaris, Evanthia I Giannoula
PURPOSE: Typically formulated by investigators from "world centres of excellence," differentiated thyroid carcinoma (DTC) management guidelines may have more limited applicability in settings of less expert care and fewer resources. Arguably the world's leading DTC guidelines are those of the American Thyroid Association, revised in 2009 ("ATA 2009") and 2015 ("ATA 2015"). To further explore the issue of "real-world applicability" of DTC guidelines, we retrospectively compared indications for ablation using ATA 2015 versus ATA 2009 in a two-centre cohort of ablated T1-2, M0 DTC patients (N = 336)...
August 25, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27540892/prognostic-factors-for-early-and-long-term-remission-in-pediatric-differentiated-thyroid-carcinoma-the-role-of-sex-age-clinical-presentation-and-the-newly-proposed-american-thyroid-association-risk-stratification-system
#13
Barbara Pereira Pires, Paulo Alonso Garcia Alves, Maria Alice Bordallo, Daniel Alves Bulzico, Flavia Paiva Proença Lobo Lopes, Terence Farias, Fernando Dias, Roberto Araújo Lima, Izabella Costa Santos Gisler, Claudia Medina Coeli, Raquel Vasconcellos Carvalhaes de Oliveira, Rossana Corbo, Mario Vaisman, Fernanda Vaisman
BACKGROUND: The incidence of pediatric differentiated thyroid carcinoma (DTC) has been rising in recent years, and the main risk factors for recurrence are lymph node and distant metastasis at diagnosis. Other clinical features remain unclear, such as the impact of age, sex, and puberty. Furthermore, until now, this population has been treated using the same strategies used to treat adults. In 2015, the American Thyroid Association (ATA) published the first guidelines targeted at this age group...
October 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27521067/2016-american-thyroid-association-guidelines-for-diagnosis-and-management-of-hyperthyroidism-and-other-causes-of-thyrotoxicosis
#14
Douglas S Ross, Henry B Burch, David S Cooper, M Carol Greenlee, Peter Laurberg, Ana Luiza Maia, Scott A Rivkees, Mary Samuels, Julie Ann Sosa, Marius N Stan, Martin A Walter
BACKGROUND: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference. This document describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist and subspecialty physicians and others providing care for patients with this condition. METHODS: The American Thyroid Association (ATA) previously cosponsored guidelines for the management of thyrotoxicosis that were published in 2011...
October 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27495016/anatomic-study-of-anterior-transdiscal-axial-screw-fixation-for-subaxial-cervical-spine-injuries
#15
Wei Ji, Minghui Zheng, Dongbin Qu, Lin Zou, Yongquan Chen, Jianting Chen, Qingan Zhu
Anterior transdiscal axial screw (ATAS) fixation is an alternative or supplement to the plate and screw constructs for the upper cervical spine injury. However, no existing literatures clarified the anatomic feasibility of this technique for subaxial cervical spine. Therefore, the objective of this study was to evaluate the anatomical feasibility and to establish guidelines for the use of the ATAS fixation for the subaxial cervical spine injury.Fifty normal cervical spines had radiographs to determine the proposed screw trajectory (the screw length and insertion angle) and the interbody graft-related parameters (the disc height and depth, and the distance between anterior vertebral margin and the screw) for all levels of the subaxial cervical spine...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27447700/national-trends-in-the-surgical-treatment-of-non-advanced-medullary-thyroid-cancer-mtc-an-evaluation-of-adherence-with-the-2009-american-thyroid-association-guidelines
#16
Eun Hae Estelle Chang, Waseem Lutfi, Joseph Feinglass, Alexandra Eudokia Reiher, Tricia Moo-Young, Mihir Kiran Bhayani
BACKGROUND: Medullary thyroid cancer (MTC) represents the third most common type of thyroid cancer, and the prognosis depends on the stage of the disease at diagnosis and completeness of tumor resection. In 2009, the American Thyroid Association (ATA) published guidelines with evidence-based recommendations for the treatment of MTC. This study aimed to determine national adherence rates of the treatment according to the ATA guidelines specific for MTC. METHODS: Patients diagnosed with MTC from 2004 to 2013 were identified from the National Cancer Database...
December 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27418023/the-changing-incidence-of-thyroid-cancer
#17
Cari M Kitahara, Julie A Sosa
During the past few decades, the incidence of thyroid cancer has increased substantially in many countries, including the USA. The rise in incidence seems to be attributable both to the growing use of diagnostic imaging and fine-needle aspiration biopsy, which has led to enhanced detection and diagnosis of subclinical thyroid cancers, and environmental factors. The latest American Thyroid Association (ATA) practice guidelines for the management of adult patients with thyroid nodules and differentiated thyroid cancer differ substantially from the previous ATA guidelines published in 2009...
November 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27368451/pediatric-thyroid-nodules-a-single-center-experience
#18
Jason Trahan, Abhita Reddy, Ellen Chang, Ricardo Gomez, Pinki Prasad, Anita Jeyakumar
OBJECTIVES: 1. Analyze our center's experience with thyroid nodules. 2. Evaluate the efficacy of fine needle biopsy. 3. Compare our experience with the 2015 ATA guidelines. METHODS: IRB approved retrospective chart review from July 1993-July 2014 at a tertiary pediatric institution. Patients under age 21 with documented thyroid nodules who underwent fine needle aspiration, and/or thyroidectomy were included. RESULTS: 126 patients were identified...
August 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27267210/new-american-thyroid-association-sonographic-patterns-for-thyroid-nodules-perform-well-in-medullary-thyroid-carcinoma-institutional-experience-systematic-review-and-meta-analysis
#19
Pablo Valderrabano, Donald L Klippenstein, John B Tourtelot, Zhenjun Ma, Zachary J Thompson, Howard S Lilienfeld, Bryan McIver
BACKGROUND: The 2015 American Thyroid Association (ATA) thyroid nodule guidelines recommend selecting nodules for biopsy based on a sonographic pattern classification. These patterns were developed based on features of differentiated thyroid cancer. This study aimed to evaluate the performance and the inter-observer agreement of this classification system in medullary thyroid carcinoma (MTC). METHODS: The medical records of all patients with MTC evaluated at the authors' institution between 1998 and 2014 were retrospectively reviewed...
August 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27266722/t1a-versus-t1b-differentiated-thyroid-cancers-do-we-need-to-make-the-distinction
#20
Kevin L Anderson, Linda M Youngwirth, Randall P Scheri, Michael T Stang, Sanziana A Roman, Julie A Sosa
BACKGROUND: The 7th edition of the American Joint Committee on Cancer (AJCC) staging system trialed a subdivision of T1 tumors into T1a (<1 cm) and T1b (1.0-2 cm). The 2009 American Thyroid Association (ATA) guidelines recommended total thyroidectomy for tumors >1 cm, and lobectomy for those ≤1 cm. These AJCC staging parameters remain a focus of debate, and ATA guidelines are in transition. The aim of this study was to determine if the T1 staging subdivision is associated with different treatment strategies and patterns of patient survival...
August 2016: Thyroid: Official Journal of the American Thyroid Association
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