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https://www.readbyqxmd.com/read/28544749/role-of-treatment-on-the-development-of-secondary-malignancies-in-patients-with-essential-thrombocythemia
#1
Cristina Santoro, Isabella Sperduti, Roberto Latagliata, Erminia Baldacci, Barbara Anaclerico, Giuseppe Avvisati, Massimo Breccia, Francesco Buccisano, Michele Cedrone, Giuseppe Cimino, Cinzia De Gregoris, Marianna De Muro, Ambra Di Veroli, Sabrina Leonetti Crescenzi, Marco Montanaro, Enrico Montefusco, Raffaele Porrini, Angela Rago, Antonio Spadea, Francesca Spirito, Nicoletta Villivà, Alesssandro Andriani, Giuliana Alimena, Maria Gabriella Mazzucconi
Aim of this study is to explore the role of different treatments on the development of secondary malignancies (SMs) in a large cohort of essential thrombocythemia (ET) patients. We report the experience of a regional cooperative group in a real-life cohort of 1026 patients with ET. We divided our population into five different groups: group 0, no treatment; group 1, hydroxyurea (HU); group 2, alkylating agents (ALK); group 3, ALK + HU sequentially or in combination; and group 4, anagrelide (ANA) and/or α-interferon (IFN) only...
May 23, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28544700/income-inequality-and-traumatic-dental-injuries-in-12-years-old-children-a-multi-level-analysis
#2
Mario Vianna Vettore, Salma Efhima, Carolina Machuca, Gabriela de Almeida Lamarca
BACKGROUND/AIM: Contextual socioeconomic factors have been associated with traumatic dental injuries (TDIs). However, evidence concerning the role of income inequality on TDIs in children is scarce.The aim of this study was to investigate the association between contextual income inequality over a ten-year period and TDIs in Brazilian children. SUBJECTS AND METHODS: The study population comprised a representative sample of 5027 children aged 12 years who participated in the Brazilian oral health survey in 2010...
May 24, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28544224/quantification-of-specific-t-and-b-cells-immunological-markers-in-children-with-chronic-and-transient-itp
#3
Sarina Levy-Mendelovich, Atar Lev, Shraga Aviner, Nurit Rosenberg, Caim Kaplinsky, Nechama Sharon, Hagit Miskin, Aviya Dvir, Gili Kenet, Irit Eisen Schushan, Raz Somech
BACKGROUND: Immune thrombocytopenic purpura (ITP) is characterized by a transient (nonchronic) or permanent (chronic) decline in the number of platelets. Predicting the course of ITP, at the time of diagnosis, is of importance. Here we studied at diagnosis, clinical and immunological parameters in order to distinguish between different courses. The latter included the measure of new B and T cells using quantification of kappa-deleting recombination excision circles (KRECs) and T-cell receptor excision circles (TRECs), respectively...
May 22, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28543814/intra-and-interindividual-variability-of-fatty-acid-unsaturation-in-six-different-human-adipose-tissue-compartments-assessed-by-1-h-mrs-in-vivo-at-3%C3%A2-t
#4
Jürgen Machann, Norbert Stefan, Robert Wagner, Malte Bongers, Erwin Schleicher, Andreas Fritsche, Hans-Ulrich Häring, Konstantin Nikolaou, Fritz Schick
It is generally accepted that the amount and distribution of adipose tissue (AT) in the human body play an important role in the pathogenesis of metabolic diseases. In addition, metabolic effects of released saturated fatty acids (FAs) in blood are known to be more critical than those of unsaturated FAs. However, little is known about the variability in unsaturation of FAs in various AT compartments. The aim of this prospective study was the assessment of mono- and polyunsaturated FAs in various AT compartments by localized (1) H-MRS in order to obtain insight into the intra- and interindividual variability...
May 25, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28543619/the-company-you-keep-is-socialising-with-higher-status-people-bad-for-mental-health
#5
Min-Ah Lee, Ichiro Kawachi
Socialising with higher-status individuals can be hypothesised to exert opposing influences on the mental health of the ego. On the one hand, socialising with higher-status alters might enable individuals to access valuable resources. On the other hand, status-discrepant friendships could be detrimental to mental health by engendering feelings of unfairness. We sought to examine the impact of status-discrepant social relationships on depressive symptoms in the 2012 Korean General Social Survey (KGSS), a nationally representative sample...
May 24, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28543321/conscientiousness-but-not-agreeableness-mediates-females-tendency-toward-being-a-morning-person
#6
Arash Rahafar, Ina Castellana, Christoph Randler, Juan Manuel Antúnez
Individuals differ in their chronotype, and some are identified as morning ones and others as evening ones. Earlier studies showed that women were higher on morningness, conscientiousness, and agreeableness. In this study, we aimed at exploring the mediational effects of conscientiousness and agreeableness in the relationship of gender and morningness-eveningness. Participants were 669 university students. Results supported positive relationships between morningness and conscientiousness and agreeableness and between conscientiousness and agreeableness...
June 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28542525/women-s-role-in-sanitation-decision-making-in-rural-coastal-odisha-india
#7
Parimita Routray, Belen Torondel, Thomas Clasen, Wolf-Peter Schmidt
BACKGROUND: While women and girls face special risks from lack of access to sanitation facilities, their ability to participate and influence household-level sanitation is not well understood. This paper examines the association between women's decision-making autonomy and latrine construction in rural areas of Odisha, India. METHODS: We conducted a mixed-method study among rural households in Puri district. This included a cross sectional survey among 475 randomly selected households...
2017: PloS One
https://www.readbyqxmd.com/read/28541817/gendered-cultural-identities-the-influences-of-family-and-privacy-boundaries-subjective-norms-and-stigma-beliefs-on-family-health-history-communication
#8
Soo Jung Hong
This study investigates the effects of cultural norms on family health history (FHH) communication in the American, Chinese, and Korean cultures. More particularly, this study focuses on perceived family boundaries, subjective norms, stigma beliefs, and privacy boundaries, including age and gender, that affect people's FHH communication. For data analyses, hierarchical multiple regression and logistic regression methods were employed. The results indicate that participants' subjective norms, stigma beliefs, and perceived family/privacy boundaries were positively associated with current FHH communication...
May 25, 2017: Health Communication
https://www.readbyqxmd.com/read/28541777/multidimensional-determinants-of-the-caregiving-burden-among-chinese-male-caregivers-of-older-family-members-in-hong-kong
#9
Xue Bai, Chang Liu, Luisa Baladon, Maria Rubio-Valera
OBJECTIVES: The objective of this study was to examine multidimensional determinants of the caregiving burden among Chinese male caregivers of older family members in Hong Kong. Based on a modified stress process model, this study explored how background and contextual factors (demographic characteristics and mental health status of caregivers, caregiving-related factors, and support and services), primary stressors (degree of care dependency and special care needs), and secondary stressors (self-efficacy and gender role conflict) might affect the caregiving burden among male caregivers...
May 25, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28540571/peer-victimization-and-unhealthy-weight-control-behaviors-the-role-of-intersecting-identities-among-new-york-city-youth
#10
Kriti Thapa, Elizabeth A Kelvin
We investigated the intersection of sexual minority, gender, and Hispanic identities, and their interaction with peer victimization in predicting unhealthy weight control behaviors (UWCB) among New York City (NYC) youths. Using logistic regression with data from the 2011 NYC Youth Risk Behavior Survey, we examined the association of sexual identity, gender, ethnicity, and peer victimization (dating violence, bullying at school, electronic bullying) in predicting UWCB. Sexual minority youths, dating violence victims, and youths bullied at school had 1...
May 24, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28540522/the-role-of-ego-resiliency-as-mediator-of-the-longitudinal-relationship-between-family-socio-economic-status-and-school-grades
#11
Guido Alessandri, Antonio Zuffianò, Nancy Eisenberg, Concetta Pastorelli
Family socio-economic status (SES) represents one of the major determinants of youth's scholastic achievement, and thus it is important to unravel the psychological factors underlining this relation. In this article, we examined youth's ability to flexibly adapt and, thus, cope with harsh environmental conditions-assessed by the construct of ego-resiliency-as a mediating mechanism in the across-time association between family SES and academic achievement. The longitudinal sample was composed of 265 (56% females) Italian students who were about 13 years old at Time 1 (T1) and about 18 years old at Time 2 (T2)...
May 24, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28540143/association-between-coronary-artery-disease-and-microrna-literature-review-and-clinical-perspective
#12
Rehan Malik, Raja S Mushtaque, Usman A Siddiqui, Adnan Younus, Muhammad A Aziz, Choudhry Humayun, Kanaan Mansoor, Muhammad A Latif, Salman Waheed, Salman Assad, Idrees Khan, Syed M Bukhari, Daniel DelCampo, Ali Adus, Swetha Gannarapu
BACKGROUND: Until recently, circulating micro-RNAs (miRNAs) have attracted major interest as novel biomarkers for the early diagnosis of coronary artery disease (CAD). This review article summarizes the available evidence on the correlation of micro-RNAs with both the clinical and subclinical coronary artery disease and highlights the necessity for exploring miRNAs as a potential diagnostic and prognostic biomarker of early CAD in an adult population. METHODS: A systematic literature analysis and retrieval online systems Public/Publisher MEDLINE/ Excerpta Medica Database /Medical Literature Analysis and Retrieval System Online,(PUBMED/EMBASE/MEDLINE) search were conducted for relevant information...
April 23, 2017: Curēus
https://www.readbyqxmd.com/read/28539425/perceptual-competition-promotes-suppression-of-reward-salience-in-behavioral-selection-and-neural-representation
#13
Mengyuan Gong, Ke Jia, Sheng Li
Visual attentional selection is influenced by the value of objects. Previous studies have demonstrated that reward-associated items lead to rapid distraction and associated behavioral costs, which are difficult to override with top-down control. However, it has not been determined whether a perceptually competitive environment could render the reward-driven distraction more susceptible to top-down suppression. Here, we trained both genders of human subjects to associate two orientations with high and low magnitudes of reward...
May 24, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28539178/gender-marital-status-and-longevity
#14
REVIEW
Gemma Tatangelo, Marita McCabe, Stephen Campbell, Cassandra Szoeke
Most studies report a positive relationship between marital status and health, with findings consistent across cultures and countries. Gender effects are significant, with men demonstrating greater health benefit than women. The vast majority of the research has examined heterosexual marriages, yet there has been rapid evolution in society of cohabitation patterns, who can marry, and roles in marriage. In this review, we summarise research findings and discuss important future challenges. Broader work looking at the impact of social connectedness, loneliness and support on survival should be supported...
June 2017: Maturitas
https://www.readbyqxmd.com/read/28539133/gender-differences-in-the-trajectories-and-the-risk-factors-of-depressive-symptoms-in-later-life
#15
Jiae Lee, Soong-Nang Jang, Sung-Il Cho
BACKGROUND: The present study investigated changes in the trajectories of depressive symptoms in the elderly and attempted to identify risk factors that influence these changes according to gender. METHODS: All data were obtained from a subsample of subjects who participated in the Korean Longitudinal Study of Ageing between 2006 and 2012; 3,667 individuals (1,566 men and 2,101 women) aged 60 years and older were included in the present study. A group-based trajectory model was employed to determine the appropriate number of groups and to observe changes in depressive symptoms according to research year...
May 25, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28538943/low-serum-chromium-is-rare-in-patients-that-underwent-endoscopic-gastrostomy-for-long-term-enteral-feeding
#16
Carla Adriana Santos, Jorge Fonseca, Elisabete Carolino, António Sousa Guerreiro
BACKGROUND: Patients that underwent Percutaneous Endoscopic Gastrostomy (PEG) present with protein-energy malnutrition. Trace elements are required in small quantities and Chromium (Cr) displays a major role in the metabolism. OBJECTIVE: This study aims to evaluate Cr levels and its relationship with serum proteins, BMI and underlying diseases during the first 3 months of PEG feeding. METHODS: Prospective observational study during 3-months, when PEG was performed (T0), after 4 (T1), and 12 weeks (T3)...
May 18, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28538912/equity-promotion-policies-in-health-for-vulnerable-groups-the-role-of-the-ministry-of-health
#17
Sandra Aparecida Venâncio de Siqueira, Eliane Hollanda, José Inácio Jardim Motta
This article aims to analyze Equity Promotion Policies in Health implemented by the Ministry of Health for vulnerable groups, through the Department of Strategy and Participative Management based on race, ethnicity, gender and lifestyle markers. The three structural elements of these policies are identified as: participatory management, transversality and awareness / professional qualifications. In carrying out research for this article, different documental sources were used including: policies, videos, conferences and minutes from council meetings as well as information from health committees...
May 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28538657/social-support-religious-involvement-and-alcohol-use-among-students-at-a-conservative-religious-university
#18
Wendy E Thompson
The misuse of alcohol among college students remains a significant public health concern in the United States. Excessive drinking among college students has been linked to numerous negative consequences, including rape, impaired academic performance, absenteeism from work and school and damaged social relations. This study examined whether religious involvement and social support played a role in reducing the frequency of alcohol use. A non-random convenience sample of 364 students from a larger study of 760 college students-18 years old and older-were recruited over a 2 month period...
May 24, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28538414/clinical-predictors-for-the-manifestation-of-late-gadolinium-enhancement-after-acute-myocardial-infarction
#19
Nadine Abanador-Kamper, Lars Kamper, Marc Vorpahl, Hilmar Brinkmann, Vasiliki Karamani, Patrick Haage, Melchior Seyfarth
Despite prompt revascularization, some patients with acute myocardial infarction (AMI) develop myocardial scars, which can be visualized by late gadolinium enhancement (LGE) in cardiovascular magnetic resonance imaging (CMR). Our goal was to identify angiographic findings that were predictive for scar development in patients after reperfused AMI.We examined 136 patients after first ST-elevated myocardial infarction by CMR after a median of 4 days (range: 2-7). Patients with manifestation of LGE were matched to patients without LGE by means of age and gender...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28538231/informal-peer-assisted-learning-groups-did-not-lead-to-better-performance-of-saudi-dental-students
#20
Maha AbdelSalam, Maha El Tantawi, Asim Al-Ansari, Adel AlAgl, Fahad Al-Harbi
OBJECTIVES: To describe peer-assisted learning (PAL) groups formed by dental undergraduate students in a biomedical course and investigate the association of individual and group characteristics with academic performance. SUBJECTS AND METHODS: In 2015, 92 4th yr. students (males: 43; females: 49) in the College of Dentistry, University of Dammam, Saudi Arabia were invited to form PAL groups to study a unit in a biomedical course. An examination was used to assess their knowledge after two weeks...
May 23, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
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