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Periprosthetic infection

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https://www.readbyqxmd.com/read/28644421/antibacterial-effect-of-a-4x-cu-tio%C3%A2-coating-simulating-acute-periprosthetic-infection-an-animal-model
#1
Andreas Mauerer, Stefanie Stenglein, Stefan Schulz-Drost, Christoph Schörner, Dominic Taylor, Sebastian Krinner, Frank Heidenau, Werner Adler, Raimund Forst
The purpose of our study was to investigate the antibacterial effect of a spacer (Ti6Al4V) coated with 4x Cu-TiO₂ in an animal model simulating an acute periprosthetic infection by Staphylococcus aureus. Ti6Al4 bolts contaminated with Staphylococcus aureus were implanted into the femoral condyle of rabbits (n = 36) divided into 3 groups. After one week in group 1 (control) the bolts were removed without any replacement. In group2 Ti6Al4V bolts with a 4x Cu-TiO₂ coating and in group 3 beads of a gentamicin-PMMA chain were imbedded into the borehole...
June 23, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28639846/antibiotic-prophylaxis-is-not-indicated-prior-to-dental-procedures-for-prevention-of-periprosthetic-joint-infections
#2
Willem M H Rademacher, Geert H I M Walenkamp, Dirk Jan F Moojen, Johannes G E Hendriks, Theo A Goedendorp, Frederik R Rozema
Background and purpose - To minimize the risk of hematogenous periprosthetic joint infection (HPJI), international and Dutch guidelines recommended antibiotic prophylaxis prior to dental procedures. Unclear definitions and contradictory recommendations in these guidelines have led to unnecessary antibiotic prescriptions. To formulate new guidelines, a joint committee of the Dutch Orthopaedic and Dental Societies conducted a systematic literature review to answer the following question: can antibiotic prophylaxis be recommended for patients (with joint prostheses) undergoing dental procedures in order to prevent dental HPJI? Methods - The Medline, Embase, and Cochrane databases were searched for randomized controlled trials (RCTs), reviews, and observational studies up to July 2015...
June 22, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28637910/excellent-diagnostic-characteristics-for-ultra-fast-gene-profiling-of-defa1-il1b-ltf-in-the-detection-of-prosthetic-joint-infections
#3
Regina Fillerova, Jiri Gallo, Martin Radvansky, Veronika Kraiczova, Milos Kudelka, Eva Kriegova
The timely and exact diagnosis of prosthetic joint infection (PJI) is crucial for surgical decision-making. Intra-operatively, delivery of the result within an hour is required. Alpha-defensin lateral immunoassay of joint fluid (JF) is precise in the intra-operative exclusion of PJI, however in patients with a limited amount of JF and/or when the JF is bloody this test is unhelpful. Important information is hidden in the periprosthetic tissues that could much better reflect the current status of implant pathology...
June 21, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28637383/inflammation-induced-osteogenesis-in-a-rabbit-tibia-model
#4
Michiel Croes, Willemijn Boot, Moyo C Kruyt, Harrie Weinans, Behdad Pouran, Yvonne van der Helm, Debby Gawlitta, Charles Vogely, Jacqueline Alblas, Wouter Dhert, F Cumhur Oner
Pathologic conditions associated with bone formation can serve as models to identify bone-promoting mediators. The inflammatory response to bacterial infections generally leads to osteolysis and impaired bone healing, but paradoxically, it can also have pro-osteogenic effects. As a potential model to investigate pro-osteogenic stimuli, this study characterizes the bone formation in an established rabbit tibia model of periprosthetic infection. Our hypothesis was that the infection with Staphylococcus aureus (S...
June 22, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28626592/diffuse-b-cell-non-hodgkin-s-lymphoma-presenting-atypically-as-periprosthetic-joint-infection-in-a-total-hip-replacement
#5
Aysha Rajeev, Angela Ralte, Nameer Choudhry, Faizan Jabbar, Paul Banaszkiewicz
The occurrence of extranodal primary B cell non-Hodgkin's lymphoma is rare. Total hip replacement is one of the most common orthopaedic procedures performed. There has been an increased incidence of primary lymphomas involving periprosthetic sites. Chronic inflammation due to metal debris arising from the prosthetic implants has been evidenced as one of the causes for the development of soft tissue lymphomas albeit rarely. We describe a case report of a 77-year-old patient who had underwent a cemented total hip replacement in the past who further developed large B cell primary non-Hodgkin's lymphoma...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28622842/two-stage-knee-arthrodesis-with-a-modular-intramedullary-nail-due-to-septic-failure-of-revision-total-knee-arthroplasty-with-extensor-mechanism-deficiency
#6
Max J Friedrich, Jan Schmolders, Matthias D Wimmer, Andreas C Strauss, Milena M Ploeger, Dieter C Wirtz, Sascha Gravius, Thomas M Randau
BACKGROUND: Periprosthetic joint infection is a serious complication and reconstruction after failed revision total knee arthroplasty with significant bone loss and compromised soft-tissues can be challenging. Objective of this study was to assess clinical and functional results, implant survival and infection recurrence rates in patients treated with two-stage arthrodesis after failed revision TKA with extensor mechanism deficiencies due to PJI, and to identify the factors that affect outcomes after surgery...
June 13, 2017: Knee
https://www.readbyqxmd.com/read/28619483/characterizing-infections-in-prosthetic-breast-reconstruction-a-validity-assessment-of-national-health-databases
#7
Merisa L Piper, Lauren O Roussel, Peter F Koltz, Frederick Wang, Kyra Singh, Robin Chin, Hani Sbitany, Howard N Langstein
INTRODUCTION: Current guidelines in the United States require reporting only the 30-day postoperative outcomes to standardized databases, including the National Surgical Quality Improvement Program (NSQIP). Thus, many breast implant-related complications go unreported in standard databases. We sought to characterize late periprosthetic infections following implant-based breast reconstruction. METHODS: We conducted a retrospective analysis of all women who underwent expander/implant reconstruction from 2005 to 2014 at two institutions...
May 18, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28611966/periprostetic-joint-infection-caused-by-salmonella-case-reports-of-two-azathioprine-and-prednisolone-induced-immunocompromised-patients
#8
Mehmet Ekinci, Serkan Bayram, Turgut Akgül, Mehmet Ersin, Önder Yazicioğlu
Periprosthetic joint infection (PJI) due to Salmonella is rare. It frequently occurs patients receiving immunosuppressive medicine. We describe two periprosthetic Salmonella infection of two immunocompromised patients. Both of patients were receiving azathioprine and prednisolone therapy. First patient presented six years after total hip arthroplasty with a huge abscess on her right thigh that was reached to femoral component through the lytic area of lateral femur. Second patient presented with drainage from his hip and he had undergone two-step revision surgery for PJI 3 months ago...
June 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/28610654/periprosthetic-infection-in-joint-replacement
#9
Christina Otto-Lambertz, Ayla Yagdiran, Franziska Wallscheid, Peer Eysel, Norma Jung
BACKGROUND: The volume of joint replacement surgery has risen steadily in recent years, because the population is aging and increasingly wishes to reserve a high functional status onward into old age. Infection is among the more common complications of joint replacement surgery, arising in 0.2% to 2% of patients, or as many as 9% in special situations such as the implantation of megaprostheses. The associated morbidity and mortality are high. It is thus very important to minimize risk factors for infection and to optimize the relevant diagnostic and therapeutic strategies...
May 26, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28608224/concordance-between-the-old-and-new-diagnostic-criteria-for-periprosthetic-joint-infection
#10
Meeri Honkanen, Esa Jämsen, Matti Karppelin, Reetta Huttunen, Outi Lyytikäinen, Jaana Syrjänen
PURPOSE: There is no uniform definition for periprosthetic joint infection (PJI). New diagnostic criteria were formulated in an international consensus meeting in 2013 and adopted by Centers for Disease Control (CDC) in 2016. The purpose of this study is to compare the new diagnostic criteria with the old CDC criteria from the year 1992. METHODS: Patients, who had been treated for PJI of hip or knee from 2002 to 2014, in a tertiary care hospital, were identified...
June 12, 2017: Infection
https://www.readbyqxmd.com/read/28606121/the-risk-factors-of-failed-reimplantation-arthroplasty-for-periprosthetic-hip-infection
#11
Shun-Wun Jhan, Yu-Der Lu, Mel S Lee, Chen-Hsiang Lee, Jun-Wen Wang, Feng-Chih Kuo
BACKGROUND: Two-stage reimplantation arthroplasty is one of the standard treatments for chronic periprosthetic joint infection (PJI). Scanty data exist regarding the risk factors for failure after two-stage reimplantation for periprosthetic hip infection. The purpose of this study was to investigate and identify the risk factors associated with failure after two-stage reimplantation hip arthroplasty. METHODS: Sixty-two patients with hip PJI treated with a two-stage reimplantation protocol at our institution from 2005 to 2012 were reviewed...
June 12, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28602532/what-is-the-difference-between-modular-and-nonmodular-tapered-fluted-titanium-stems-in-revision-total-hip-arthroplasty
#12
Yong Huang, Yixin Zhou, Hongyi Shao, Jianming Gu, Hao Tang, Qiheng Tang
BACKGROUND: Both modular and nonmodular tapered fluted titanium stems are used in revision total hip arthroplasty (THA), with follow-up showing good results for both stems. We aimed to determine whether there were any differences in clinical outcomes, survivorship, or frequency of complications. METHODS: A retrospective review of 160 consecutive THAs (153 patients) revised with a tapered fluted modular titanium stem from 2002 to 2014 and 129 consecutive THAs (128 patients) revised with a tapered fluted nonmodular titanium stem between 2008 and 2014 was conducted...
May 18, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28595609/erratum-to-high-incidence-of-periprosthetic-joint-infection-with-propionibacterium-acnes-after-the-use-of-a-stemless-shoulder-prosthesis-with-metaphyseal-screw-fixation-a-retrospective-cohort-study-of-241-patients-propionibacter-infections-after-eclipse-tsa
#13
https://www.readbyqxmd.com/read/28594503/two-stage-revision-total-knee-arthroplasty-in-the-setting-of-periprosthetic-knee-infection
#14
Zain Sayeed, Afshin A Anoushiravani, Mouhanad M El-Othmani, Monique C Chambers, William M Mihalko, William A Jiranek, Wayne G Paprosky, Khaled J Saleh
Two-stage revision total knee arthroplasty (TKA) is the standard of care for patients who require a revision procedure for the mangement of a late or chronic periprosthetic knee infection. A careful examination of two-stage revision TKA is warranted as the number of patients who require revision TKA in the United States continues to rise. Surgeons should understand the intricacies involved in two-stage revision TKA, including the indications, procedural variations, and current deliberations on two-stage revision TKA in the literature...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28594502/single-stage-revision-total-knee-arthroplasty-in-the-setting-of-periprosthetic-knee-infection-indications-contraindications-and-postoperative-outcomes
#15
Afshin A Anoushiravani, Zain Sayeed, Mouhanad M El-Othmani, Monique C Chambers, William M Mihalko, William A Jiranek, Wayne G Paprosky, Khaled J Saleh
Single-stage revision total knee arthroplasty has become an increasingly common treatment option for patients with failed knee prostheses. Periprosthetic knee infection is the leading and most devastating cause of revision total knee arthroplasty. Although periprosthetic knee infection has been extensively studied in the orthopaedic literature, the role of single-stage revision total knee arthroplasty for the treatment of periprosthetic knee infection warrants further research. As healthcare reform shifts from a volume-based to a value-based system, it is imperative that orthopaedic surgeons understand the procedural indications, risks, and benefits of single-stage revision total knee arthroplasty...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28594501/prevention-and-diagnosis-of-periprosthetic-knee-infection
#16
Bilal Mahmood, Mouhanad M El-Othmani, William M Mihalko, William A Jiranek, Wayne G Paprosky, Khaled J Saleh
Total knee arthroplasty (TKA) has become an increasingly common treatment option for patients who have debilitating knee arthritis. TKA is a relatively safe and efficient procedure that results in promising outcomes and has a positive effect on a patient's quality of life. More TKAs are being performed annually because the procedure substantially reduces pain and improves functionality; however, as the number of TKAs continues to rise, there is concern for potential complications that may result in prosthetic joint failure...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28591963/-extensively-porous-coated-distal-fixation-long-stem-prosthesis-for-unstable-proximal-femur-fracture-with-complex-hip-disease
#17
Song Hong, Jia-Sheng Lin, Yong Zhou, Chang Zou, Wen-Li Zhang, Hong Duan, Chong-Qi Tu
OBJECTIVES: To evaluate the clinical results of femoral proximal fracture with complex hip diseases using an uncemented extensively porous-coated long femoral stems. METHODS: 15 cases of femoral proximal fracture with complex hip diseases treated with the uncemented extensively porous-coated long femoral stem were retrospectively reviewed. All patients were followed up at 1, 3, 6, 12 months in the first year postoperatively and once a year from the second year on...
July 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28590378/increasing-body-mass-index-is-associated-with-worse-outcomes-after-shoulder-arthroplasty
#18
Eric R Wagner, Matthew T Houdek, Cathy Schleck, William S Harmsen, Joaquin Sanchez-Sotelo, Robert Cofield, John W Sperling, Bassem T Elhassan
BACKGROUND: Although obesity is associated with increased complication rates after lower-extremity arthroplasty, there is a relative paucity of studies examining the effect of body mass index (BMI) on shoulder arthroplasty. The purpose of this investigation was to evaluate the effect of BMI on implant survival and the rate of complications after shoulder arthroplasty. METHODS: Using an institutional total joint registry, 4,567 consecutive shoulder arthroplasty cases from 1970 to 2013 were studied...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28590375/familial-clustering-identified-in-periprosthetic-joint-infection-following-primary-total-joint-arthroplasty-a-population-based-cohort-study
#19
Mike B Anderson, Karen Curtin, Jathine Wong, Christopher E Pelt, Christopher L Peters, Jeremy M Gililland
BACKGROUND: It is estimated that the cost to treat periprosthetic joint infection in the United States will approach $1.62 billion by 2020. Thus, the need to better understand the pathogenesis of periprosthetic joint infection is evident. We performed a population-based, retrospective cohort study to determine if familial clustering of periprosthetic joint infection was observed. METHODS: Analyses were conducted using software developed at the Utah Population Database (UPDB) in conjunction with the software package R...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28588662/management-of-painful-reverse-shoulder-arthroplasty
#20
REVIEW
Anders L Ekelund
Even though reverse shoulder arthroplasty is a very successful procedure, painful complications occur. During the initial postoperative years, the most common reasons for pain are instability, postoperative fracture of the acromion or spine, and periprosthetic infection. Later, aseptic loosening, with humeral loosening being more frequent that glenoid loosening, can be a source of pain and reduction in function. A careful patient history, clinical examination, plain radiographs, computed tomography and blood tests give an explanation for the pain in most cases...
July 2017: Shoulder & Elbow
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