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D G Chang, R M Healey, A J Snyder, J V Sayson, B R Macias, D G Coughlin, J F Bailey, S E Parazynski, J C Lotz, A R Hargens
STUDY DESIGN: Prospective case series. OBJECTIVE: Evaluate lumbar paraspinal muscle (PSM) cross-sectional area and intervertebral disc (IVD) height changes induced by a 6-month space mission on the International Space Station (ISS). The long-term objective of this project is to promote spine health and prevent spinal injury during space missions as well as here on Earth. SUMMARY OF BACKGROUND: NASA crewmembers have a 4.3 times higher risk of herniated IVDs, compared to the general and military aviator populations...
October 25, 2016: Spine
Stefano Strano, Alessandra Fanciulli, Massimiliano Rizzo, Paolo Marinelli, Paolo Palange, Dorina Tiple, Giuseppe De Vincentis, Giovanni Calcagnini, Federica Censi, Giuseppe Meco, Carlo Colosimo
BACKGROUND: The clinical presentation of Parkinson's disease (PD) includes a wide spectrum of non-motor features, including cardiovascular autonomic failure. OBJECTIVE: To evaluate cardiovascular autonomic status and cardiac functional capacity in drug-naïve PD patients. METHODS: 18 newly-diagnosed PD patients underwent laboratory cardiovascular autonomic function tests using power spectral analysis of the R-R interval, blood pressure (BP) short-term variability and non-invasive baroreflex sensitivity (BRS)...
November 15, 2016: Journal of the Neurological Sciences
Larry E Miller, William G Herbert
Spinal cord injury (SCI) is a traumatic, life-disrupting event with an annual incidence of 17,000 cases in the US. SCI is characterized by progressive physical deconditioning due to limited mobility and lack of modalities to allow safe physical activity that may partially offset these deleterious physical changes. Approximately, 50% of patients with SCI report no leisure-time physical activity and 15% report leisure-time physical activity below the threshold where meaningful health benefits could be realized...
2016: ClinicoEconomics and Outcomes Research: CEOR
Attila Oláh, Dalma Kellermayer, Csaba Mátyás, Balázs Tamás Németh, Árpád Lux, Lilla Szabó, Marianna Török, Mihály Ruppert, Anna Meltzer, Alex Ali Sayour, Kálmán Benke, István Hartyánszky, Béla Merkely, Tamás Radovits
PURPOSE: Long-term exercise training is associated with characteristic cardiac adaptation, termed athlete's heart. Our research group previously characterized in vivo left ventricular (LV) function of exercise-induced cardiac hypertrophy in detail in a rat model, however the effect of detraining on LV function is still unclear. We aimed at evaluating the reversibility of functional alterations of athlete's heart after detraining. METHODS: Rats (n=16) were divided into detrained exercised (DEx) and detrained control (DCo) groups...
October 14, 2016: Medicine and Science in Sports and Exercise
Kristen T Crowell, David I Soybel, Charles H Lang
Muscle deconditioning is commonly observed in patients surviving sepsis. Little is known regarding the molecular mechanisms regulating muscle protein homeostasis during the recovery or convalescence phase. We adapted a sepsis-recovery mouse model that uses cecal ligation and puncture (CLP), followed 24 h later by cecal resection and antibiotic treatment, to identify putative cellular pathways regulating protein synthesis and breakdown in skeletal muscle. Ten days after CLP, body weight and food consumption did not differ between control and sepsis-recovery mice, but gastrocnemius weight was reduced...
October 5, 2016: Shock
Zach Rozenbaum, Shafik Khoury, Galit Aviram, Yaniv Gura, Jack Sherez, Avi Man, Jason Shimiaie, Thierry Le Tourneau, Amir Halkin, Simon Biner, Gad Keren, Yan Topilsky
BACKGROUND: Discriminating circulatory problems with reduced stroke volume from de-conditioning in which the muscles cannot consume O2 normally by gas exchange parameters is difficult. METHODS: We performed combined stress echo and cardio-pulmonary (CPET) tests in 110 patients (20 normal effort capacity, 54 attenuated stroke volume response, 36 de-conditioning) to evaluate multiple hemodynamic parameters and oxygen content difference (A-VO2 Difference) in four predefined activity levels to assess which of the gas measures may help in the discrimination...
October 11, 2016: Chest
Katie Hatt, Nicholas C Kinback, Anoop Shah, Ernesto Cruz, Eric L Altschuler
Since the late 1980s, lung transplant has become an option for some individuals (in 2014 4000 lung transplants were performed) with end-stage lung disease aimed to help these individuals restore function and improve survival and quality of life. Individuals living with end-stage lung disease are already deconditioned with poor endurance and limited exercise capacity. There are additional post-transplant factors which can contribute to poor endurance and decreased exercise capacity. While pulmonary rehabilitation in the pre-transplant phase is a crucial component for positive functional outcomes following lung transplant, the incidence of post-transplant complications, coupled with the need for immunosuppression often warrants close monitoring by medical professionals...
October 6, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Svetlana Blitshteyn, David Fries
No abstract text is available yet for this article.
September 2016: Pulmonary Circulation
Rim Maaoui, Emna Bahlouli, Imen Ksibi, Hanen Khiari, Hajer Rahali
OBJECTIVE: Psychosocial factors appear increasingly decisive in functional disability related to chronic low-back pain. Catastrophizing and kinesiophobia lead to deconditioning and the perpetuation of pain. The purpose of this study is to evaluate fear, beliefs, catastrophizing and kinesiophobia in chronic low-back pain patients about to begin a training programme in a rehabilitation centre. MATERIAL/PATIENTS AND METHODS: Retrospective study conducted in the department of physical and rehabilitation medicine in the Military Tunis hospital between March and June 2015, concerning patients followed for chronic low-back pain...
September 2016: Annals of Physical and Rehabilitation Medicine
Julien Nardoux
OBJECTIVE: Chronic low-back pain is accompanied by physical deconditioning which result among other by lower VO2max and by disturbances isokinetic explorations. The objective of this study was to investigate whether there was a correlation between VO2max and isokinetic parameters spine before and after a functional restoration program (FRP). MATERIAL/PATIENTS AND METHODS: Uni-centric retrospective study in routine care. Isokinetic spine muscle strength evaluation and functional exercise exploration were performed before and after FRP for all hospitalized patients for 4 weeks to FRP...
September 2016: Annals of Physical and Rehabilitation Medicine
Maxime Valet, Gaëtan Stoquart, Yumiko Glibert, Jean-Claude Hakizimana, Thierry Lejeune
OBJECTIVE: Fatigue is the most common and disabling symptom among patients suffering from multiple sclerosis (MS). From the initial stages of the disease, a physical deconditioning is also observed among these patients. The aim of this study is to assess the cardiorespiratory endurance (i.e. exercise tolerance functions) and self-reported fatigue, as well as their associations, among patients suffering from MS with mild disability (expanded disability status scale≤4). MATERIALS/PATIENTS AND METHODS: 21 patients with MS (15 women; age: 26-64 years, median 46 years; duration of disease: 0...
September 2016: Annals of Physical and Rehabilitation Medicine
Laurent Savalli, Maria Isabel Hernandez Sendin, Laure Lacombe
OBJECTIVE: Is it possible to substitute the isokinetic tests by isometric tests to determine back muscle deconditioning syndrome in CLBP patients? PATIENTS AND METHODS: Thirty-five CLBP patients, of a 39.7 years median age, 14 females and 21 males, included in a program of the type trunk reconditionning carried out the isokinetic and isometric tests on dynamometer CONTREX 2000*. The isometric tests were carried out with 15°, 30° and 45° of inflection of the trunk with and without correction of gravity...
September 2016: Annals of Physical and Rehabilitation Medicine
Anne-Sophie Dolez, Azahara Alcantara, Romain Mouny
The Montévrain clinic wants to be a medical center oriented towards autonomy and recovery of patient autonomy, reintegration within the family, as well as social and professional reintegration. After studying the care offer and the population base in Seine et Marne, we wanted to get involved in order to improve the capacity of patients treated for breast cancer, suffering deconditioning, with or without joint limitation and functional impairment, with or without a mental deterioration. We studied the recommendations of the "plan cancer III", researched the tertiary phase of cancer treatment and studied literature about evaluation of the physical and mental condition...
September 2016: Annals of Physical and Rehabilitation Medicine
Jacques Vaillant, Perrine Revillet, Anne-Marie Sevenier, Robert Juvin
OBJECTIVE: Fibromyalgia fatigue was described as an overwhelming feeling of tiredness that is not relieved by sleep or rest and is often not in proportion to the effort realized. In fibromyalgia syndrome (FMS), the fatigue has an important functional impact, often limiting the activities of daily living, can induce a state of deconditioning, and causing disturbance of locomotion, whose reasons are not fully understood. The aims of this study was to evaluate the postural performance in quite standing of FMS patients, and to compare them to a control group, and to assess the influence on the posture of a fatigue induced by a short walk...
September 2016: Annals of Physical and Rehabilitation Medicine
Sung Ho Jang, Hyeok Gyu Kwon
BACKGROUND: Little is known about delay in regaining gait ability at a chronic stage after brain injury. In this study, we report on a single patient who regained the gait ability during 2 months of intensive rehabilitation starting 2 years after a brain injury. METHODS AND RESULTS: A 40-year-old male patient diagnosed with viral encephalitis underwent comprehensive rehabilitation until 2 years after onset. However, he could not even sit independently and presented with severe physical deconditioning and severe ataxia...
September 2016: Medicine (Baltimore)
Dolores Sánchez-Rodríguez, Ester Marco, Natalia Ronquillo-Moreno, Ramón Miralles, Olga Vázquez-Ibar, Ferran Escalada, Josep M Muniesa
BACKGROUNDS & AIMS: The European Society of Clinical Nutrition and Metabolism (ESPEN) consensus definition of malnutrition has been applied in hospitalized older diabetics and middle-aged patients, geriatric outpatients, and healthy elderly and young individuals. In a post-acute care setting, our aim was to assess malnutrition (ESPEN definition) and determine its relationship with sarcopenia in older in-patients deconditioned due to an acute process. METHODS: Eighty-eight in-patients aged ≥70 years with body mass index (BMI) <30 kg/m(2) were included (84...
September 9, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Nicola Lamberti, Sofia Straudi, Anna M Malagoni, Matteo ARGIRò, Michele Felisatti, Eleonora Nardini, Christel Zambon, Nino Basaglia, Fabio Manfredini
BACKGROUND: Chronic stroke survivors are exposed to long-term disability and physical deconditioning, effects that may impact their independence and quality of life. Community-based programs optimizing the dose of exercise therapy that are simultaneously low risk and able to achieve high adherence should be identified. AIM: We tested the hypothesis that an 8-week, community-based, progressive mixed endurance- resistance exercise program at lower cardiovascular and muscular load yielded more mobility benefits than a higher-intensity program in chronic stroke survivors...
September 14, 2016: European Journal of Physical and Rehabilitation Medicine
Kathryn Booth, Josh Rivet, Richelle Flici, Ellen Harvey, Mark Hamill, Douglas Hundley, Katelyn Holland, Sandra Hubbard, Apurva Trivedi, Bryan Collier
The intensive care unit (ICU) trauma population is at high risk for complications associated with immobility. The purpose of this project was to compare ICU trauma patient outcomes before and after implementation of a structured progressive mobility (PM) protocol. Outcomes included hospital and ICU stays, ventilator days, falls, respiratory failure, pneumonia, or venous thromboembolism (VTE). In the preintervention cohort, physical therapy (PT) consults were placed 53% of the time. This rose to more than 90% during the postintervention period...
September 2016: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
Michael J Ellis, John Leddy, Barry Willer
Historically, patients with sports-related concussion (SRC) have been managed in a uniform fashion consisting mostly of prescribed physical and cognitive rest with the expectation that all symptoms will spontaneously resolve with time. Although this approach will result in successful return to school and sports activities in the majority of athletes, an important proportion will develop persistent concussion symptoms characteristic of post-concussion syndrome (PCS). Recent advances in exercise science, neuroimaging, and clinical research suggest that the clinical manifestations of PCS are mediated by unique pathophysiological processes that can be identified by features of the clinical history and physical examination as well as the use of graded aerobic treadmill testing...
2016: Frontiers in Neurology
Dongsheng Jiang, Weihong Kong, Joanna J Jiang
BACKGROUND: Physicians encounter various symptom-based complaints each day. While physicians strive to support patients with chronic illnesses, evidence indicates that patients who are actively involved in their health care have better health outcomes and sometimes lower costs. AIM: This article is to analyze how patient engagement is described when complex interventions such as Tai Chi were delivered in randomized controlled clinical trials (RCTs). It reviews the dynamic patient-physician relationship in chronic illness management and to illustrate the patient engagement process, using Tai Chi as an example intervention...
August 15, 2016: Reviews on Recent Clinical Trials
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