keyword
MENU ▼
Read by QxMD icon Read
search

Taurine

keyword
https://www.readbyqxmd.com/read/28819768/maternal-obesity-is-associated-with-gut-microbial-metabolic-potential-in-offspring-during-infancy
#1
Tomás Cerdó, Alicia Ruiz, Ruy Jáuregui, Hatim Azaryah, Francisco José Torres-Espínola, Luz García-Valdés, M Teresa Segura, Antonio Suárez, Cristina Campoy
Children born to obese mothers are at increased risk for obesity, but the mechanisms behind this association are not fully understood. Our study aimed to investigate differences in the functions encoded by the microbiome of infants at 18 months of age when the transition from early infant-feeding to solid family foods is established. To investigate the impact of maternal prepregnancy body mass index on infants' gut microbiome, faecal samples from infants born to normoweight (n = 21) and obese mothers (n = 18) were analysed by 16S rRNA gene sequencing and a functional-inference-based microbiome analysis...
August 17, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28813705/the-lncrna-tug1-ezh2-axis-promotes-pancreatic-cancer-cell-proliferation-migration-and-emt-phenotype-formation-through-sponging-mir-382
#2
Liang Zhao, Hongwei Sun, Hongru Kong, Zongjing Chen, Bicheng Chen, Mengtao Zhou
BACKGROUND/AIMS: Pancreatic carcinoma (PC) is the one of the most common and malignant cancers worldwide. LncRNA taurine upregulated gene 1 (TUG1) was initially identified as a transcript upregulated by taurine, and the abnormal expression of TUG1 has been reported in many cancers. However, the biological role and molecular mechanism of TUG1 in PC still needs further investigation. METHODS: Quantitative real-time PCR (qRT-PCR) was performed to measure the expression of TUG1 in PC cell lines and tissues...
August 15, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28810965/the-benefits-and-risks-of-energy-drinks-in-young-adults-and-military-service-members
#3
Julianne Manchester, Inbal Eshel, Donald W Marion
INTRODUCTION: Energy drinks (EDs) have become an integral part of the young adult, athletic, and military culture. Many athletes are convinced that EDs enhance performance, and service members as well as college students frequently use EDs as stimulants to counter sleep deprivation, or to improve academic performance. However, concerns have been raised by some military leaders about potential adverse effects of EDs. MATERIALS AND METHODS: A needs assessment survey of a convenience sample of military health care providers was conducted and identified EDs as a top knowledge need for those providers working in the area of traumatic brain injury (TBI)...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28808902/genetic-diversity-population-structure-and-correlations-between-locally-adapted-zebu-and-taurine-breeds-in-brazil-using-snp-markers
#4
Bárbara Machado Campos, Adriana Santana do Carmo, Andrea Alves do Egito, Arthur Silva da Mariante, Maria Socorro Muaés do Albuquerque, João José Simoni de Gouveia, Carlos Henrique Mendes Malhado, Lucas Lima Verardo, Marcos Vinícius Gualberto Barbosa da Silva, Paulo Luiz Souza Carneiro
Genetic diversity is one of the most important issues in studies on conservation of cattle breeds and endangered species. The objective of this study was to estimate the levels of genetic differentiation between locally adapted taurine (Bos taurus taurus) and zebu (Bos taurus indicus) breeds in Brazil, which were genotyped for more than 777,000 SNPs. The fixation index (F ST), principal component analysis (PCA), and Bayesian clustering were estimated. The F ST highlighted genetic differentiation between taurine and zebu breeds...
August 15, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28806601/influence-of-sublethal-doses-of-acetamiprid-and-halosulfuron-methyl-on-metabolites-of-zebra-fish-brachydanio-rerio
#5
Hong Zhang, Lijuan Zhao
Acetamiprid, a neonicotinoid pesticide, is reported to have adverse sublethal effects on non-target beneficial organisms. Halosulfuron-methyl (HM), one of the most widely used herbicides in agriculture, has high ecotoxicity to aquatic plants and animals. In this study, a GC-MS-based metabolomics approach was used to investigate the toxicity of acetamiprid and HM. The Automated Mass Spectral Deconvolution and Identification System (AMDIS) software program and the retention index method were used to identify 51 metabolites in zebra fish (Brachydanio rerio)...
August 4, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28803365/energy-drinks-and-their-component-modulate-attention-memory-and-antioxidant-defences-in-rats
#6
M T Costa Valle, N S Couto-Pereira, C Lampert, D M Arcego, A P Toniazzo, R P Limberger, E Dallegrave, C Dalmaz, M D Arbo, M B Leal
PURPOSE: This study aimed to evaluate the effects of the subchronic consumption of energy drinks and their constituents (caffeine and taurine) in male Wistar rats using behavioural and oxidative measures. METHODS: Energy drinks (ED 5, 7.5, and 10 mL/kg) or their constituents, caffeine (3.2 mg/kg) and taurine (40 mg/kg), either separately or in combination, were administered orally to animals for 28 days. Attention was measured though the ox-maze apparatus and the object recognition memory test...
August 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28802060/taurine-upregulated-gene-1-functions-as-a-master-regulator-to-coordinate-glycolysis-and-metastasis-in-hepatocellular-carcinoma
#7
Yang-Hsiang Lin, Meng-Han Wu, Ya-Hui Huang, Chau-Ting Yeh, Mei-Ling Cheng, Hsiang-Cheng Chi, Chung-Ying Tsai, I-Hsiao Chung, Ching-Ying Chen, Kwang-Huei Lin
Cancer cells display altered glucose metabolism characterized by a preference for aerobic glycolysis. The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often correlated with tumor progression and poorer clinical outcomes. However, the issue of whether glycolytic metabolism influences metastasis in HCC remains unclear. In the current study, we showed that knockdown of Taurine upregulated gene 1 (TUG1) induces marked inhibition of cell migration, invasion and glycolysis via suppression of miR-455-3p...
August 12, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28801262/the-physiological-and-pathophysiological-roles-of-taurine-in-adipose-tissue-in-relation-to-obesity
#8
REVIEW
Shigeru Murakami
Obesity is caused by an imbalance between energy intake and energy expenditure. It is established that obesity is a state of low-grade chronic inflammation, which is characterized by enlarged hypertrophied adipocytes, increased infiltration by macrophages and marked changes in the secretion of adipokines and free fatty acids. The effects of taurine on the pathogenesis of obesity have been reported in animals and humans. Although the mechanisms underlying the anti-obesity action of taurine remain to be defined, taurine seems to ameliorate obesity through stimulation of energy expenditure, modulation of lipid metabolism, anorexic effect, anti-inflammatory and anti-oxidative effects...
August 8, 2017: Life Sciences
https://www.readbyqxmd.com/read/28793864/in-vitro-examination-of-the-positive-inotropic-effect-of-caffeine-and-taurine-the-two-most-frequent-active-ingredients-of-energy-drinks
#9
R Chaban, A Kornberger, N Branski, K Buschmann, N Stumpf, A Beiras-Fernandez, C F Vahl
BACKGROUND: Our study aimed to evaluate changes in the contractile behavior of human myocardium after exposure to caffeine and taurine, the main active ingredients of energy drinks (EDs), and to evaluate whether taurine exhibits any inotropic effect at all in the dosages commonly used in EDs. METHODS: Myocardial tissue was removed from the right atrial appendages of patients undergoing cardiac surgery and prepared to obtain specimens measuring 4 mm in length. A total of 92 specimens were exposed to electrical impulses at a frequency of 75 bpm for at least 40 min to elicit their maximum contractile force before measuring the isometric contractile force (ICF) and duration of contraction (CD)...
August 10, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28782569/the-protective-effects-of-electro-acupuncture-in-thoracic-surgery-on-trauma-stressed-rats-involve-the-rostral-ventrolateral-medulla-and-supraoptic-nucleus
#10
Huan-Huan Zhang, Yi-Nan Tao, Mei-Yan Jiang, Jin Wang, Jun Chen, Chun-Mei Xia, Lin-Lin Shen, Meng-Ya Wang, Da-Nian Zhu
The present study was designed to explore whether the rostral ventrolateral medulla (RVLM) and supraoptic nucleus (SON) were involved in the protective effects of electro-acupuncture (EA) on cardiac function in thoracic surgery on trauma-stressed rats. The rats were randomly divided into a non-stressed group (Control), surgical trauma-stressed group (Trauma), and Neiguan EA applied on the surgical trauma-stressed group (Trauma+EA-PC 6). RVLM neuron discharge was observed by using an in vivo electrophysiological method, and micro-dialysis combining high-performance liquid chromatography with fluorometric detection (HPLC-FD) was used to assess expression of amino acids in the RVLM...
August 3, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28776911/long-non-coding-rnas-as-an-epigenetic-regulator-in-human-cancers
#11
REVIEW
Yutaka Kondo, Keiko Shinjo, Keisuke Katsushima
Recent studies have demonstrated the important multiple roles of long non-coding RNAs (lncRNAs) during oncogenic transformation. Because the coding genome accounts for a small amount of total DNA, and many mutations leading to cancer occur in the non-coding genome, it is plausible that the dysregulation of such non-coding transcribes might also affect tumor phenotypes. Indeed, to date, lncRNAs have been reported to affect diverse biological processes through the regulation of mRNA stability, RNA splicing, chromatin structure, and miRNA-mediated gene regulation by acting as miRNA sponges...
August 4, 2017: Cancer Science
https://www.readbyqxmd.com/read/28774887/suppressed-hepatic-bile-acid-signalling-despite-elevated-production-of-primary-and-secondary-bile-acids-in-nafld
#12
Na Jiao, Susan S Baker, Adrian Chapa-Rodriguez, Wensheng Liu, Colleen A Nugent, Maria Tsompana, Lucy Mastrandrea, Michael J Buck, Robert D Baker, Robert J Genco, Ruixin Zhu, Lixin Zhu
OBJECTIVE: Bile acids are regulators of lipid and glucose metabolism, and modulate inflammation in the liver and other tissues. Primary bile acids such as cholic acid and chenodeoxycholic acid (CDCA) are produced in the liver, and converted into secondary bile acids such as deoxycholic acid (DCA) and lithocholic acid by gut microbiota. Here we investigated the possible roles of bile acids in non-alcoholic fatty liver disease (NAFLD) pathogenesis and the impact of the gut microbiome on bile acid signalling in NAFLD...
August 3, 2017: Gut
https://www.readbyqxmd.com/read/28771380/antioxidant-and-osmoprotecting-activity-of-taurine-in-dry-eye-models
#13
Claudio Bucolo, Annamaria Fidilio, Chiara Bianca Maria Platania, Federica Geraci, Francesca Lazzara, Filippo Drago
PURPOSE: To assess the protective effects of ophthalmic formulations based on taurine (TAU) and sodium hyaluronate (SH) in ocular surface. METHODS: Rabbit corneal epithelial cells [Statens Seruminstitut Rabbit Cornea (SIRC)] were subjected to oxidative stress (1 mM H2O2) and treated with the following formulations: 0.2% SH, 0.4% SH, 0.4% SH +0.5% TAU. Reactive oxygen species (ROS) were evaluated by commercial kit. Dry eye was induced by atropine sulfate and topical treatment was carried out with the following formulations: 0...
August 3, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28770521/styrene-maleic-acid-encapsulated-raloxifene-micelles-for-management-of-inflammatory-bowel-disease
#14
Khaled Greish, Safa Taha, Anfal Jasim, Sara Abd Elghany, Ameera Sultan, Ali AlKhateeb, Manal Othman, Fang Jun, Sebastien Taurin, Moiz Bakhiet
BACKGROUND: Inflammatory bowel disease (IBD) comprises a group of disorders that manifest through chronic inflammation of the colon and small intestine. Although the exact cause of IBD is still unclear, dysfunctional immunoregulation involving overproduction of inflammatory cytokines such as TNF-α, and IL-6 have been implicated in pathogenesis. Current therapy relies on immunosuppression, cytotoxic drugs, and monoclonal antibodies against TNF-α. These classes of drugs have severe side-effects, especially when used for long duration...
December 2017: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/28766169/retinoid-acid-and-taurine-promote-neurod1-induced-differentiation-of-induced-pluripotent-stem-cells-into-retinal-ganglion-cells
#15
Li Huang, Mengfei Chen, Weizhong Zhang, Xuerong Sun, Bingqian Liu, Jian Ge
Induced pluripotent stem cells (iPSCs) possess the capacity to differentiate into multiple cell types including retinal neurons. Despite substantial progress in the transcriptional regulation of iPSC differentiation process, the efficiency of generation of retinal neurons from iPSCs is still low. In this study, we investigated the role of transcription factor NeuroD1 in the differentiation of iPSCs into retinal neurons. We observed that retrovirus-mediated NeuroD1 overexpression in iPSCs increased the efficiency of neuronal differentiation...
August 1, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28765943/acute-and-chronic-effects-of-taurine-magnesium-coordination-compound-on-cardiac-sodium-channel-nav1-5
#16
Lin Zhao, Xiao-Xu Yang, Yong-Qiang Yin, Hong Wu, Yi Kang, Jian-Shi Lou
It has been previously demonstrated that taurine magnesium coordination compound (TMCC) produces antiarrhythmic effects in vivo. The present study investigated the acute and chronic effect of TMCC on sodium channels in HEK cells stably expressing human cardiac Nav1.5 sodium channels. The current amplitude, activation and inactivation kinetics, recovery time from inactivation, and use‑dependent block of sodium channels were analyzed using the whole‑cell patch clamp technique. Western blotting was used to analyze Nav1...
July 31, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28765866/-evaluation-of-nutritional-characteristics-of-commercial-canned-cat-diets
#17
Cornelia Rückert, Conny Braun, Ingrid Vervuert
OBJECTIVE: To evaluate commercial complete canned cat foods according to their composition, labeling and nutritional characteristics. MATERIALS AND METHODS: A total of 21 commercial complete canned compound feeds for adult cats were analyzed for crude nutrients, minerals, vitamins, selected amino acids and taurine. The analyzed parameters were compared to the internal set of standards of the European Pet Food Industry Federation (FEDIAF). The energy content was calculated and compared with the labeled recommendations regarding the amounts of diet that should be fed...
August 2, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28763771/taurine-grafting-and-collagen-adsorption-on-plla-films-improve-human-primary-chondrocyte-adhesion-and-growth
#18
Luca Pellegrino, Rossana Cocchiola, Iolanda Francolini, Mariangela Lopreiato, Antonella Piozzi, Robertino Zanoni, Anna Scotto d'Abusco, Andrea Martinelli
Biocompatible and degradable poly(α-hydroxy acids) are one of the most widely used materials in scaffolds for tissue engineering. Nevertheless, they often need surface modification to improve interaction with cells. Aminolysis is a common method to increase the polymer hydrophilicity and to introduce surface functional groups, able to covalently link or absorb, through electrostatic interaction, bioactive molecules or macromolecules. For this purpose, multi-functional amines, such as diethylenediamine or hexamethylenediamine are used...
July 23, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28763759/metabolomics-analysis-of-danggui-sini-decoction-on-treatment-of-collagen-induced-arthritis-in-rats
#19
Bang Cheng, Hua Zheng, Fang Wu, Jinxia Wu, Xuwen Liu, Chaoling Tang, Shiyin Lu, Zhaoni Chen, Fangming Song, Junxiang Ruan, Hongye Zhang, Hui Song, Wei Liu, Hongwei Guo, Yonghong Liang, Zhiheng Su
Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by persistent joint inflammation leading to bone and cartilage damage and even disability. However, the pathogenesis of RA is multi-factorial and to a large degree, remains unknown. Danggui Sini decoction (DSD), a traditional Chinese medicine (TCM) formula, has been widely used as a remedy for rheumatoid arthritis (RA) in recent years. In our study, (1)H-nuclear magnetic resonance ((1)H NMR) based metabolomics analysis of 7 potential biomarkers, including taurine (1), urea (2), betaine (3), pyruvate (4), hippurate (5), succinate (6) and acetone (7) was performed to investigate the progression of RA and assess the efficacy of DSD in collagen-induced arthritis (CIA) rats...
July 24, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28757580/role-of-mitochondria-and-endoplasmic-reticulum-in-taurine-deficiency-mediated-apoptosis
#20
Chian Ju Jong, Takashi Ito, Howard Prentice, Jang-Yen Wu, Stephen W Schaffer
Taurine is a ubiquitous sulfur-containing amino acid found in high concentration in most tissues. Because of its involvement in fundamental physiological functions, such as regulating respiratory chain activity, modulating cation transport, controlling inflammation, altering protein phosphorylation and prolonging lifespan, taurine is an important nutrient whose deficiency leads to severe pathology and cell death. However, the mechanism by which taurine deficiency causes cell death is inadequately understood...
July 25, 2017: Nutrients
keyword
keyword
5929
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"