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Calcium ct score

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https://www.readbyqxmd.com/read/28528881/impact-of-calcium-score-on-agreement-between-multidetector-computed-tomography-and-invasive-coronary-angiography
#1
José Alberto de Agustín, José Juan Gómez de Diego, Pedro Marcos-Alberca, Patricia Mahía, José Luis Rodrigo, María Luaces, Iván Javier Núñez-Gil, Joaquín Ferreiros, Ana Bustos, Beatriz Cabeza, Miguel Ángel García-Fernández, Carlos Macaya, Leopoldo Pérez de Isla
INTRODUCTION AND OBJECTIVES: Multidetector computed tomography (MDCT) has been demonstrated as a feasible alternative to invasive coronary angiography (ICA). However, contradictory results have been reported regarding the effect of coronary artery calcium score (CS) on the diagnostic accuracy of MDCT. Our aim was to assess the agreement of MDCT and ICA and to evaluate the influence of CS on this agreement. METHODS: We enrolled 266 consecutive patients who underwent evaluation with 64-slice MDCT and ICA...
May 18, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28528743/-18-f-sodium-fluoride-positron-emission-tomography-for-molecular-imaging-of-coronary-atherosclerosis-based-on-computed-tomography-analysis
#2
Toshiro Kitagawa, Hideya Yamamoto, Shinya Toshimitsu, Ko Sasaki, Atsuhiro Senoo, Yumiko Kubo, Fuminari Tatsugami, Kazuo Awai, Yutaka Hirokawa, Yasuki Kihara
BACKGROUND AND AIMS: We aimed at evaluating the relation of (18)F-sodium fluoride ((18)F-NaF) uptake on positron emission tomography (PET) to coronary atherosclerosis detected and assessed by computed tomography (CT). METHODS: Thirty-two patients with one or more coronary atherosclerotic lesions detected on cardiac CT underwent (18)F-NaF PET/CT. Each coronary atherosclerotic lesion was evaluated on CT angiography for plaque types (calcified plaque [CP], non-calcified plaque [NCP], partially calcified plaque [PCP]), and the presence of CT-based high-risk features (minimum CT density <30 Hounsfield units and vascular remodeling index >1...
April 29, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28521653/matrix-metalloproteinase-3-gene-polymorphism-rs3025058-affects-markers-atherosclerosis-in-type-2-diabetes-mellitus
#3
Aleš Pleskovič, Marija Šantl Letonja, Andreja Cokan Vujkovac, Jovana Nikolajević Starčević, Martin Caprnda, Eduard Curilla, Ioana Mozos, Peter Kruzliak, Robert Prosecky, Daniel Petrovič
BACKGROUND: The study was designed to test the possible association between either polymorphisms of the matrix metalloproteinase-9 (MMP-9) gene (rs17576, rs3918242) or the MMP-3 5A/6A gene polymorphism (rs3025058) with markers of carotid atherosclerosis in patients with type 2 diabetes mellitus (T2DM). The second aim of the study was to demonstrate an association between either the rs17576, rs3918242 or rs3025058 and subclinical markers of coronary artery disease in the same subset of patients with T2DM...
May 19, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28513225/use-of-the-augmentation-index-from-applanation-tonometry-of-the-radial-artery-for-assessing-the-extent-of-coronary-artery-calcium-as-assessed-by-coronary-computed-tomography
#4
Noriaki Watanabe, Satoshi Kurisu, Yoji Sumimoto, Hiroki Ikenaga, Takashi Shimonaga, Tadanao Higaki, Fuminari Tatsugami, Ken Ishibashi, Toshiro Kitagawa, Yoshihiro Dohi, Yukihiro Fukuda, Hideya Yamamoto, Kazuo Awai, Yasuki Kihara
BACKGROUND: The augmentation index (AI) obtained from applanation tonometry of the radial artery is technically the easiest and quickest of available methods for assessing arterial stiffness. We tested the hypothesis that the radial AI is associated with the extent of coronary artery calcium (CAC) as assessed by coronary computed tomography (CCT). METHODS AND RESULTS: This study included 161 patients with known or suspected coronary artery disease undergoing central hemodynamic measurements and CCT...
May 17, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28502735/effects-of-low-calcium-dialysate-on-the-progression-of-coronary-artery-calcification-in-hemodialysis-patients-an-open-label-12-month-randomized-clinical-trial
#5
Soo Jin Kim, Young-Ki Lee, Jieun Oh, AJin Cho, Jung Woo Noh
BACKGROUND: The association between the dialysate calcium level and coronary artery calcification (CAC) has not yet been evaluated in hemodialysis patients. The objective of this study was to determine whether lowering the dialysate calcium levels would decrease the progression of coronary artery calcification (CAC) compared to using standard calcium dialysate. METHODS: We conducted an open-label randomized trial with parallel groups. The patients were randomly assigned to either 12-month treatment with low calcium dialysate (LCD; 1...
May 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28502500/the-association-between-dietary-cholesterol-intake-and-subclinical-atherosclerosis-in-korean-adults-the-kangbuk-samsung-health-study
#6
Eun-Jung Rhee, Seungho Ryu, Jong-Young Lee, Sung Ho Lee, EunSun Cheong, Se Eun Park, Cheol-Young Park, Yu Sam Won, Joon Mo Kim, Dong-Sik Cho, Hye-Kyung Chung, Ki Chul Sung
BACKGROUND: The Scientific Report of the Dietary Guidelines Advisory Committee (2015) concluded that restriction of dietary cholesterol is unnecessary in most adults for the prevention of cardiovascular disease. OBJECTIVE: We aimed to assess the risk for subclinical atherosclerosis according to coronary artery calcium score (CACS), based on dietary cholesterol intake in apparently healthy Korean adults. METHODS: This was a cross-sectional study performed in 30,068 participants (mean age 40...
March 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28501727/methods-to-evaluate-arterial-structure-and-function-in-children-state-of-the-art-knowledge
#7
REVIEW
Piotr Skrzypczyk, Małgorzata Pańczyk-Tomaszewska
BACKGROUND: With increasing rates of hypertension, obesity, and diabetes in the pediatric population, wide available, and reproducible methods are necessary to evaluate arterial structure and function in children and adolescents. METHODS: MEDLINE/Pubmed was searched for articles published in years 2012-2017 on methodology of, current knowledge on, and limitations of the most commonly used methods to evaluate central, proximal and coronary arteries, as well as endothelial function in pediatric patients...
May 11, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28500370/long-term-prognostic-performance-of-low-dose-coronary-computed-tomography-angiography-with-prospective-electrocardiogram-triggering
#8
Olivier F Clerc, Basil P Kaufmann, Mathias Possner, Riccardo Liga, Jan Vontobel, Fran Mikulicic, Christoph Gräni, Dominik C Benz, Tobias A Fuchs, Julia Stehli, Aju P Pazhenkottil, Oliver Gaemperli, Philipp A Kaufmann, Ronny R Buechel
OBJECTIVES: To assess long-term prognosis after low-dose 64-slice coronary computed tomography angiography (CCTA) using prospective electrocardiogram-triggering. METHODS: We included 434 consecutive patients with suspected or known coronary artery disease referred for low-dose CCTA. Patients were classified as normal, with non-obstructive or obstructive lesions, or previously revascularized. Coronary artery calcium score (CACS) was assessed in 223 patients. Follow-up was obtained regarding major adverse cardiac events (MACE): cardiac death, myocardial infarction and elective revascularization...
May 12, 2017: European Radiology
https://www.readbyqxmd.com/read/28499609/achilles-tendon-xanthomas-are-associated-with-the-presence-and-burden-of-subclinical-coronary-atherosclerosis-in-heterozygous-familial-hypercholesterolemia-a-pilot-study
#9
Leonardo C Mangili, Marcio H Miname, Pamela R S Silva, Marcio S Bittencourt, Viviane Z Rocha, Otavio C Mangili, Wilson Salgado Filho, Ana P Chacra, Cinthia E Jannes, Alexandre C Pereira, Raul D Santos
BACKGROUND AND AIMS: Achilles tendon xanthomas (ATX) are a sign of long-term exposure to high blood cholesterol in familial hypercholesterolemia (FH) patients, which have been associated with cardiovascular disease. We evaluated the ATX association with the presence and extent of subclinical coronary atherosclerosis in heterozygous FH patients. METHODS: 102 FH patients diagnosed by US-MEDPED criteria (67% with genetically proven FH), with median LDL-C 279 mg/dL (interquartile range: 240; 313), asymptomatic for cardiovascular disease, underwent computed tomography angiography and coronary artery calcium (CAC) quantification...
April 30, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28493399/diagnosis-of-fatty-liver-by-computed-tomography-coronary-artery-calcium-score
#10
Sarah E Kerut, John T Balart, Edmund K Kerut, Michael R McMullan
Nonalcoholic fatty liver disease may range from simple steatosis to fibrosis and cirrhosis. It is associated with the development of coronary artery calcification and appears to be an independent predictor of future adverse cardiovascular events. As the presence of a fatty liver appears to portray an independent increased risk, it may be beneficial to note this on coronary artery calcium scoring reports. Determination of fatty liver is relatively easy to perform. We discuss the method used by the Multi-Ethnic Study of Atherosclerosis (MESA) study for determination of fatty liver from CT coronary artery calcium scoring acquisitions, which may be implemented in clinical analysis...
May 11, 2017: Echocardiography
https://www.readbyqxmd.com/read/28492571/-teamwork-for-cardiac-imaging-coronary-computed-tomography-angiography-and-low-dose-radiation-exposure-a-cardiology-center-experience
#11
Massimo Magnacca, Rosa Poddighe, Jacopo Del Meglio, Alessio Lilli, Marco Tullio Baratto, Maria Laura Canale, Carlo Tessa, Luca Salvatori, Alessandra Niespolo, Claudio Vignali, Giancarlo Casolo
BACKGROUND: Multidetector coronary computed tomography angiography (CCTA) is increasingly used for noninvasive imaging of the coronary arteries. Radiation exposure, however, is a potential limitation to a more extensive use of this imaging modality. We aimed to demonstrate that a professional teamwork approach, including a cardiologist and a radiologist in performing CCTA, may allow to obtain best quality exams with very low radiation doses. METHODS: A total of 998 consecutive patients underwent CCTA in accordance with the most recent guidelines...
April 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28491082/altered-serum-level-of-cartilage-oligomeric-matrix-protein-and-its-association-with-coronary-calcification-in-patients-with-coronary-heart-disease
#12
Fang-Fang Wang, Lahati Ha, Hai-Yi Yu, Lin Mi, Jiang-Li Han, Wei Gao
BACKGROUND: Cartilage oligomeric matrix protein (COMP) is mainly found in the skeletal system and vascular smooth muscle cells. Recent researches showed that it had a protective function on blood vessels and could also inhibit vascular calcification. We investigated the serum COMPs in coronary heart disease (CHD) patients, and the relationship between serum COMP and the calcification of coronary artery. METHODS: A total of 233 consecutive chest pain patients who first underwent coronary angiography followed by multi-slice computed tomography (MSCT) within six months were recruited and divided into two groups according to the coronary angiography luminal diameter narrowing percentages: CHD group (diameter narrowing ≥ 50%, n = 194) and control group (diameter narrowing < 50%, n = 39)...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28483581/prognostic-value-of-segment-involvement-score-compared-to-other-measures-of-coronary-atherosclerosis-by-computed-tomography-a-systematic-review-and-meta-analysis
#13
Chadi Ayoub, Fernanda Erthal, Mahmoud A Abdelsalam, M Hassan Murad, Zhen Wang, Patricia J Erwin, Graham S Hillis, Leonard Kritharides, Benjamin J W Chow
BACKGROUND: The segment involvement score (SIS) is a semiquantitative measure of the extent of atherosclerosis burden by coronary computed tomography angiography (CTA). We sought to evaluate by meta-analysis the prognostic value of SIS, and to compare it with other CTA measures of coronary artery disease (CAD). METHODS: Electronic databases from 1946 to January 2016 were searched. Studies reporting SIS, or an equivalent measure by coronary CTA, and clinical outcomes were included...
May 3, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28479451/prognostic-value-of-aortoiliac-calcification-score-in-kidney-transplantation-recipients
#14
Bertrand Chavent, Nicolas Maillard, Claire Boutet, Jean-Noël Albertini, Ambroise Duprey, Jean-Pierre Favre
BACKGROUND: Kidney recipients are increasingly older with arterial disease and extended arterial calcifications. In a kidney transplantation population, the prognosis value of aortic and iliac calcifications remains poorly explored. We aimed to assess the impact of pre-transplantation Aortoiliac vascular calcifications on patients, grafts survival and cardiovascular events. METHODS: This retrospective study included kidney transplantation patients from 2006 to 2012 for whom we had available pre-surgery abdominal computed tomography results (n=100)...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28465287/prevalence-of-subclinical-coronary-artery-disease-in-masters-endurance-athletes-with-a-low-atherosclerotic-risk-profile
#15
Ahmed Merghani, Viviana Maestrini, Stefania Rosmini, Andrew T Cox, Harshil Dhutia, Rachel Bastiaenen, Sarojini David, Tee Joo Yeo, Rajay Narain, Aneil Malhotra, Michael Papadakis, Mathew G Wilson, Maite Tome, Khaled AlFakih, James C Moon, Sanjay Sharma
Background -Studies in middle aged and older (masters) athletes with atherosclerotic risk factors for coronary artery disease (CAD) report higher coronary artery calcium (CAC) scores compared with sedentary individuals. Few studies have assessed the prevalence of CAD in masters athletes with a low atherosclerotic risk profile. Methods -We assessed 152 masters athletes aged 54.4±8.5 years (70% male) and 92 controls of similar age, sex and low Framingham 10 year CAD risk scores with an echocardiogram, exercise stress test, CT coronary angiogram, and cardiovascular magnetic resonance imaging (CMRI) with late gadolinium enhancement (LGE) and a 24-hour Holter...
May 2, 2017: Circulation
https://www.readbyqxmd.com/read/28457950/practical-determination-of-aortic-valve-calcium-volume-score-on-contrast-enhanced-computed-tomography-prior-to-transcatheter-aortic-valve-replacement-and-impact-on-paravalvular-regurgitation-elucidating-optimal-threshold-cutoffs
#16
Nicolas Bettinger, Omar K Khalique, Joseph M Krepp, Nadira B Hamid, David J Bae, Todd C Pulerwitz, Ming Liao, Rebecca T Hahn, Torsten P Vahl, Tamim M Nazif, Isaac George, Martin B Leon, Andrew J Einstein, Susheel K Kodali
BACKGROUND: The threshold for the optimal computed tomography (CT) number in Hounsfield Units (HU) to quantify aortic valvular calcium on contrast-enhanced scans has not been standardized. Our aim was to find the most accurate threshold to predict paravalvular regurgitation (PVR) after transcatheter aortic valve replacement (TAVR). METHODS: 104 patients who underwent TAVR with the CoreValve prosthesis were studied retrospectively. Luminal attenuation (LA) in HU was measured at the level of the aortic annulus...
April 22, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28454833/changes-in-cardiovascular-medication-after-coronary-artery-calcium-scanning-and-normal-single-photon-emission-computed-tomography-myocardial-perfusion-imaging-in-symptomatic-patients
#17
Elsemiek M Engbers, Jorik R Timmer, Mohamed Mouden, Siert Knollema, Pieter L Jager, Jan Paul Ottervanger
The impact of coronary artery calcium (CAC) scoring on subsequent changes in cardiovascular medication use in symptomatic patients with normal myocardial perfusion imaging (MPI) findings is not well established. The aim of the current study was to evaluate changes in aspirin and statin use in patients suspected for coronary artery disease after CAC scoring and normal single photon emission computed tomography (SPECT) MPI. METHODS: In the current study, 1,033 stable symptomatic patients without a known history of coronary artery disease with normal SPECT MPI who underwent concomitant CAC scoring were included...
April 2017: American Heart Journal
https://www.readbyqxmd.com/read/28453572/assessment-of-coronary-artery-calcium-by-chest-ct-compared-with-ekg-gated-cardiac-ct-in-the-multicenter-aids-cohort-study
#18
Divay Chandra, Aman Gupta, Joseph K Leader, Meghan Fitzpatrick, Lawrence A Kingsley, Eric Kleerup, Sabina A Haberlen, Matthew J Budoff, Mallory Witt, Wendy S Post, Frank C Sciurba, Alison Morris
RATIONALE: Individuals with HIV are at increased risk for coronary artery disease (CAD). Early detection of subclinical CAD by assessment of coronary artery calcium (CAC) may help risk stratify and prevent CAD events in these individuals. However, the current standard to quantify CAC i.e. Agatston scoring requires EKG-gated cardiac CT imaging. OBJECTIVE: To determine if the assessment of CAC using non-EKG-gated chest CT and the Weston scoring system is a useful surrogate for Agatston scores in HIV-infected and HIV-uninfected individuals...
2017: PloS One
https://www.readbyqxmd.com/read/28449836/aortic-calcification-progression-in-heterozygote-familial-hypercholesterolemia
#19
Manal Al Kindi, Alexandre M Bélanger, Karl Sayegh, Soumia Senouci, Sumayah Aljenedil, Lojan Sivakumaran, Isabelle Ruel, Khalid Al Rasadi, Khalid Al Waili, Zuhier Awan, David Valenti, Jacques Genest
BACKGROUND: Patients with homozygous and heterozygous familial hypercholesterolemia (HeFH) develop severe aortic calcifications in an age- and gene dosage-dependent manner. The purpose of this study was to determine the rate of progression of aortic calcification in patients with HeFH. METHODS: We performed thoracoabdominal computed tomography scans and quantified aortic calcium (AoCa) score in 16 HeFH patients, all with the null low-density lipoprotein (LDL) receptor DEL15Kb mutation...
May 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28449466/higher-coronary-artery-calcification-score-is-associated-with-adverse-prognosis-in-patients-with-stable-angina-pectoris
#20
Renrong Wang, Xiaoxiao Liu, Chunxia Wang, Xinhe Ye, Xin Xu, Chengjian Yang
BACKGROUND: Coronary artery calcification (CAC) indicates the presence of atherosclerotic lesions and serves as a marker of prognosis in patients with coronary artery disease (CAD). This study evaluated the value of the CAC score for determining the prognosis of patients with stable angina pectoris (SAP). METHODS: A total of 106 consecutive patients with SAP were enrolled in this study from January 2011 to June 2014; from these patients, 640 multi-slice computer tomography (MSCT) samples were used to obtain CAC scores...
March 2017: Journal of Thoracic Disease
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