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https://www.readbyqxmd.com/read/29321389/aortic-root-calcification-score-as-an-independent-factor-for-predicting-major-adverse-cardiac-events-in-familial-hypercholesterolemia
#1
Hirofumi Okada, Hayato Tada, Kenshi Hayashi, Hiroki Kawashima, Tadanori Takata, Kenji Sakata, Atsushi Nohara, Hiroshi Mabuchi, Masakazu Yamagishi, Masa-Aki Kawashiri
AIM: The aims of this study were: 1) to determine whether the accumulation of aortic root calcification (ARC) assessed using coronary computed tomography angiography (CCTA) can predict future cardiovascular events, and 2) to estimate the onset and progression of ARC in patients with familial hypercholesterolemia (FH). METHODS: One hundred thirteen consecutive Japanese patients with heterozygous FH (male=54, mean age=52.1±15.6 years, mean LDL-C=299.0±94.6 mg/dL), without known coronary artery disease, who underwent 64-detector row CCTA were retrospectively evaluated...
January 10, 2018: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29310329/impact-of-iterative-reconstruction-vs-filtered-back-projection-on-image-quality-in-320-slice-ct-coronary-angiography-insights-from-the-core320-multicenter-study
#2
Ahmed Fareed, Andrea L Vavere, Elke Zimmermann, Yutaka Tanami, Chloe Steveson, Matthew Matheson, Narinder Paul, Melvin Clouse, Christopher Cox, João A C Lima, Armin Arbab-Zadeh
Iterative reconstruction has been shown to reduce image noise compared with traditional filtered back projection with quantum denoising software (FBP/QDS+) in CT imaging but few comparisons have been made in the same patients without the influence of interindividual factors. The objective of this study was to investigate the impact of adaptive iterative dose reduction in 3-dimensional (AIDR 3D) and FBP/QDS+-based image reconstruction on image quality in the same patients.We randomly selected 100 patients enrolled in the coronary evaluation using 320-slice CT study who underwent CT coronary angiography using prospectively electrocardiogram triggered image acquisition with a 320-detector scanner...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29305347/maintenance-of-ideal-cardiovascular-health-and-coronary-artery-calcium-progression-in-low-risk-men-and-women-in-the-framingham-heart-study
#3
Shih-Jen Hwang, Oyere Onuma, Joseph M Massaro, Xiaoling Zhang, Yi-Ping Fu, Udo Hoffmann, Caroline S Fox, Christopher J O'Donnell
BACKGROUND: Ideal cardiovascular health (CVH) is associated with a lower risk of cardiovascular disease and freedom from coronary artery calcium (CAC). Prospective data on the association between maintenance of optimal CVH and the progression of subclinical coronary atherosclerosis are limited. We assessed the influence of unfavorable versus favorable CVH on the incidence of CAC progression. METHODS AND RESULTS: The study population consisted of 1119 FHS (Framingham Heart Study) participants who attended the serial FHS MDCT I and MDCT II study (Multi-Detector Computed Tomography) and had a zero Agatston CAC score at baseline...
January 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29298566/osteochondral-interface-stiffening-in-mandibular-condylar-osteoarthritis
#4
J Zhang, L Liao, J Zhu, X Wan, M Xie, H Zhang, M Zhang, L Lu, H Yang, D Jing, X Liu, S Yu, X L Lu, C Chen, Z Shan, M Wang
Osteoarthritis (OA) of the temporomandibular joint (TMJ) is associated with dental biomechanics. A major change during OA progression is the ossification of the osteochondral interface. This study investigated the formation, radiological detectability, and mechanical property of the osteochondral interface at an early stage, the pathogenesis significance of which in OA progression is of clinical interest and remains elusive for the TMJ. Unilateral anterior crossbite (UAC) was performed on 6-wk-old rats as we previously reported...
December 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29291201/sickle-cell-and-alpha-thalassemia-traits-resulting-in-non-atherosclerotic-myocardial-infarction-beyond-coincidence
#5
Lee S Nguyen, Alban Redheuil, Olivier Mangin, Joe-Elie Salem
Alpha-thalassemia trait and sickle trait are not commonly considered risk factors of ischemic heart disease. We report the case of a non-atherosclerotic silent myocardial infarction in a 46-year-old woman, carrier of the alpha-thalassemia trait (homozygous deletion of locus -3.7) combined with sickle cell trait. While the patient was included as healthy volunteer for a metabolic study, we performed cardiac magnetic resonance imagery showing a left ventricle apicolateral myocardial infarction. Coronary computed tomography angiography showed normal coronary arteries with a coronary calcium score of 0...
December 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29285727/influence-of-heart-rate-on-coronary-calcium-scores-a-multi-manufacturer-phantom-study
#6
N R van der Werf, M J Willemink, T P Willems, R Vliegenthart, M J W Greuter, T Leiner
To evaluate the influence of heart rate on coronary calcium scores (CCS) using a dynamic phantom on four high-end computed tomography (CT) systems from different manufacturers. Artificial coronary arteries were moved in an anthropomorphic chest phantom at linear velocities, corresponding to < 60, 60-75 and > 75 beats per minute (bpm). Data was acquired with routinely used clinical protocols for CCS on four high-end CT systems (CT1-CT4). CCS, quantified as Agatston and mass scores were compared to reference scores at < 60 bpm...
December 28, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29285725/influence-of-iterative-reconstruction-on-coronary-calcium-scores-at-multiple-heart-rates-a-multivendor-phantom-study-on-state-of-the-art-ct-systems
#7
N R van der Werf, M J Willemink, T P Willems, M J W Greuter, T Leiner
The objective of this study was to evaluate the influence of iterative reconstruction on coronary calcium scores (CCS) at different heart rates for four state-of-the-art CT systems. Within an anthropomorphic chest phantom, artificial coronary arteries were translated in a water-filled compartment. The arteries contained three different calcifications with low (38 mg), medium (80 mg) and high (157 mg) mass. Linear velocities were applied, corresponding to heart rates of 0, < 60, 60-75 and > 75 bpm...
December 28, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29273883/calcification-of-the-iliac-arteries-a-marker-for-leakage-risk-in-rectal-anastomosis-a-blinded-clinical-trial
#8
Julius Pochhammer, Fridolin Tröster, Gunnar Blumenstock, Julienne Closset, Stefanie Lang, Marie-Pascale Weller, Michael Schäffer
PURPOSE: Anastomotic leakage (AL) is associated with increased morbidity and mortality after colorectal surgery. Calcification of the arteries has been identified as a risk factor for cardiovascular events and can be reliably measured on computed tomography using software assistance. The aim of this prospective study was to prove the value of calcium scoring of the iliac arteries as a predictor of AL after rectal anastomosis. METHODS: Consecutive patients who underwent colorectal resection with rectal anastomosis were analyzed...
December 22, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29260893/accuracy-of-coronary-artery-calcium-scoring-with-tube-current-reduction-by-75-using-an-adaptive-iterative-reconstruction-algorithm
#9
Reny Luhur, Joanne D Schuijf, Jügen Mews, Jörg Blobel, Bernd Hamm, Alexander Lembcke
OBJECTIVE: To assess the accuracy of an iterative reconstruction (IR) technique for coronary artery calcium scoring with reduced radiation dose. METHODS: 163 consecutive patients underwent twofold scanning by 320-row detector computed tomography (CT) at 120 kVp. A low-dose scan at 25% tube current but with standard scan length (14 cm) was followed by a standard dose scan with routine tube current but reduced scan length (10 cm). Reduced dose images were constructed using filtered back-projection (FBP) and IR (adaptive iterative dose reduction in 3 dimensions, or AIDR3D)...
December 20, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29247160/the-proper-use-of-coronary-calcium-score-and-coronary-computed-tomography-angiography-for-screening-asymptomatic-patients-with-cardiovascular-risk-factors
#10
Shee Yen Tay, Po-Yen Chang, Wilson T Lao, Ying Chin Lin, Yi-Han Chung, Wing P Chan
Early detection and treatment of coronary artery disease (CAD) can reduce incidences of acute myocardial infarction. In this study, we determined the proper use of contributing risk factors and coronary artery calcium score (CACS) when screening asymptomatic patients with coronary arterial stenoses using coronary computed tomography angiography (CCTA). We reviewed 934 consecutive patients who received CACS and CCTA between December 2013 and November 2016. At least one cardiovascular disease risk factor was present in each of the 509 asymptomatic participants...
December 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29239051/coronary-and-carotid-atherosclerosis-in-asymptomatic-male-marathon-runners
#11
Christof Burgstahler, Hans Cipowicz, Christoph Thomas, Christoph Schabel, Stefanie Mangold, Dominik Ketelsen, Claus D Claussen, Andreas M Niess, Ilias Tsiflikas
The aim of the study was to evaluate the diagnostic accuracy of carotid ultrasound (CU) to predict coronary atherosclerosis in asymptomatic male marathon runners. A total of 49 male marathon runners older than 45 years(mean age 53.3±7.2 years, range 45-74 years) received CU and cardiac CT angiography(CTA) including calcium scoring(CS). Results of CU and CTA were classified binary: 1. Absence of atherosclerosis and 2. presence of atherosclerosis. The extend of atherosclerosis was not primary end-point of the study...
December 14, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29236239/abdominal-aorta-and-pelvic-artery-calcifications-on-plain-radiographs-may-predict-mortality-in-chronic-kidney-disease-hemodialysis-and-renal-transplantation
#12
Sinee Disthabanchong, Kotcharat Vipattawat, Bunyong Phakdeekitcharoen, Chagriya Kitiyakara, Vasant Sumethkul
PURPOSE: Vascular calcification is common in chronic kidney disease (CKD) and predicts poor patient outcomes. While computed tomography is the gold standard for evaluation of vascular calcification, plain radiograph offers a simpler and less costly alternative. The calcification of abdominal aorta, iliac and femoral arteries has been evaluated by plain radiograph, but the data on their outcome predictabilities are still limited. The present study investigated the role of abdominal aortic calcification (AAC) and pelvic arterial calcification (PAC) in predicting overall morality in non-dialysis CKD stages 2-5 (CKD 2-5), maintenance hemodialysis (HD) and long-term kidney transplant (KT) patients...
December 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29233634/epicardial-adipose-tissue-density-and-volume-are-related-to-subclinical-atherosclerosis-inflammation-and-major-adverse-cardiac-events-in-asymptomatic-subjects
#13
Markus Goeller, Stephan Achenbach, Mohamed Marwan, Mhairi K Doris, Sebastien Cadet, Frederic Commandeur, Xi Chen, Piotr J Slomka, Heidi Gransar, J Jane Cao, Nathan D Wong, Moritz H Albrecht, Alan Rozanski, Balaji K Tamarappoo, Daniel S Berman, Damini Dey
BACKGROUND: We investigated whether epicardial adipose tissue (EAT) volume and density are related to early atherosclerosis, plaque inflammation and major adverse cardiac events (MACE, cardiac death and myocardial infarction) in asymptomatic subjects. METHODS: EAT volume and density were quantified from non-contrast cardiac CT in 456 asymptomatic individuals (age 60.3 ± 8.3; 68% with CCS>0) from the prospective EISNER trial. EAT volume and density were examined in relation to coronary calcium score (CCS), inflammatory biomarkers and MACE...
November 24, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29225032/calcification-of-thoracic-and-abdominal-aneurysms-is-associated-with-mortality-and-morbidity
#14
Mohammed M Chowdhury, Lukasz P Zieliński, James J Sun, Simon Lambracos, Jonathan R Boyle, Seamus C Harrison, James H F Rudd, Patrick A Coughlin
INTRODUCTION: Cardiovascular events are common in people with aortic aneurysms. Arterial calcification is a recognised predictor of cardiovascular outcomes in coronary artery disease. Whether calcification within abdominal and thoracic aneurysm walls is correlated with poor cardiovascular outcomes is not known. PATIENTS AND METHODS: Calcium scores were derived from computed tomography (CT) scans of consecutive patients with either infrarenal (AAA) or descending thoracic aneurysms (TAA) using the modified Agatston score...
December 7, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29221971/preventive-treatment-with-lomerizine-increases-cerebral-blood-flows-during-the-interictal-phase-of-migraine
#15
Ken Ikeda, Joe Aoyagi, Sayori Hanashiro, Masahiro Sawada, Maya Kyuzen, Harumi Morioka, Junya Ebina, Junpei Nagasawa, Masaru Yanagihashi, Yuichi Ishikawa, Ken Miura, Kiyoko Murata, Takanori Takazawa, Kiyokazu Kawabe, Yasuo Iwasaki
BACKGROUND: Changes in regional cerebral blood flow (rCBF) were reported in migraineurs. However, little is known how preventive medications of migraine can influence rCBF. Lomerizine, a calcium channel blocker, has been used for migraine prophylaxis in Japan. We examined rCBF after lomerizine treatment. SUBJECTS AND METHODS: Migraine was diagnosed according to the criteria of the International Classification of Headache Disorders, Third Edition beta. Migraine subtype was classified into migraine with aura (MA) and migraine without aura (MO)...
December 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29220061/comparison-of-carotid-intima-media-thickness-and-coronary-artery-calcium-score-for-estimating-subclinical-atherosclerosis-in-patients-with-fatty-liver-disease
#16
Hyun-Jin Kim, Hyung-Bok Park, Yongsung Suh, Yoon-Hyeong Cho, Eui-Seok Hwang, Deok-Kyu Cho, Tae-Young Choi
INTRODUCTION: Fatty liver disease (FLD) is correlated with cardiovascular disease. Carotid intima-media thickness (CIMT) and coronary artery calcium score (CACS) can noninvasively identify subclinical atherosclerosis and predict risk for cardiovascular events. This study evaluated CIMT and CACS measurements to detect subclinical atherosclerosis in patients with and without FLD. METHODS: Patients who underwent carotid and abdominal ultrasounds as well as cardiac computed tomography (CT) scans were evaluated retrospectively...
December 8, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/29214447/association-between-common-bile-duct-diameter-and-abdominal-aorta-calcium-score
#17
Yashar Moharamzad, Sahar Abbasi, Morteza Sanei Taheri, Taraneh Faghihi Langroudi
BACKGROUND AND OBJECTIVE: There is evidence of association between aging and increase in the normal upper limit of the common bile duct (CBD) diameter. As aging is a documented risk factor for atherosclerosis, and the possible effect that atherosclerosis can have on the CBD diameter via affecting its smooth muscle contractility and blood flow, we decided to determine the association between CBD diameter and atherosclerosis in the abdominal aorta (AA). METHODS: A total of 99 asymptomatic patients (53 males and 46 females; age range of 18-88 years) without history of cholecystectomy who underwent abdominal contrast-enhanced CT scan were included...
December 6, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29208173/transforming-growth-factor-%C3%AE-1-gene-polymorphism-and-osteoporosis-in-postmenopausal-egyptian-women
#18
Inass M Taha, Azza M Abdu Allah, Maha A F Hamoudah, S Justin Carlus
Transforming growth factor-β1 (TGF-β1) is a wide spread bone matrix protein that affect the function, formation and cell-cell interactions of osteoclasts and osteoblasts to regulate bone remodeling and sustain adequate bone mass. The aim of this study is to evaluate the role of the two polymorphism of transforming growth factor-β1 T869C and C-509T in developing osteoporosis in postmenopausal Egyptian women. This study was performed on 138 postmenopausal osteoporosis/osteopenic women and 128 postmenopausal female control group...
November 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/29195787/high-risk-plaque-and-calcification-detected-by-coronary-ct-angiography-to-predict-future-cardiovascular-events-after-percutaneous-coronary-intervention
#19
Nobuo Tomizawa, Kodai Yamamoto, Shinichi Inoh, Takeshi Nojo, Sunao Nakamura
RATIONALE AND OBJECTIVES: The purpose of this study was to investigate whether high-risk plaque (HRP) and calcium assessed by coronary computed tomography (CT) could predict future cardiovascular events after second-generation drug-eluting stent (DES) placement. MATERIALS AND METHODS: We analyzed 317 patients from December 2012 to April 2015 who underwent coronary CT followed by DES placement. HRP was defined as a plaque with positive remodeling and low attenuation or a plaque with a napkin-ring sign...
November 29, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29191782/comparison-of-the-hemodynamic-performance-of-the-balloon-expandable-sapien-3-versus-self-expandable-evolut-r-transcatheter-valve-a-case-matched-study
#20
Eduardo Enríquez-Rodríguez, Ignacio J Amat-Santos, Pilar Jiménez-Quevedo, Irene Martín-Morquecho, Gabriela Tirado-Conte, María José Pérez-Vizcayno, José Juan Gómez de Diego, Roman Arnold, Andrés Aldazábal, Paol Rojas, Alberto de Agustín, María Del Trigo, Hipólito Gutiérrez, José A San Román, Carlos Macaya, Luis Nombela-Franco
INTRODUCTION AND OBJECTIVES: The SAPIEN 3 (S3) valve and the Medtronic Evolut R (EVR) are second-generation transcatheter valves, designed to further reduce the rate of paravalvular aortic regurgitation (AoR). The aim of this study was to compare the 2 devices in terms of valve performance in a case-matched study with independent echocardiographic analysis. METHODS: Of a population of 201 patients who underwent transcatheter aortic valve implantation, 144 patients (S3, n = 80; EVR, n = 64) were matched according to aortic annulus diameter and aortic valve calcium score, as assessed by computed tomography...
November 27, 2017: Revista Española de Cardiología
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