Read by QxMD icon Read


D Saul, B Harlas, A Ahrabi, R L Kosinsky, D B Hoffmann, M Wassmann, R Wigger, K O Böker, S Sehmisch, M Komrakova
Osteoporosis is often accompanied by sarcopenia. The effect of strontium ranelate (SR) on muscle tissue has not been investigated sufficiently. In this study, the effect of different SR treatments on muscle was studied. Additionally, the lumbar vertebrae were analyzed. Three-month-old female rats were divided into five groups (n = 12): Group 1: untreated (NON-OVX); Group 2: ovariectomized and left untreated (OVX); Group 3: SR after OVX until the study ended (13 weeks, SR prophylaxis and therapy = pr+th); Group 4: OVX and SR for 8 weeks (SR prophylaxis = pr); Group 5: SR for 5 weeks from the 8 week after OVX (SR therapy = SR th)...
December 14, 2017: Calcified Tissue International
Haidong Lu, Daesu Lee, Konstantin Klyukin, Lingling Tao, Bo Wang, Hyungwoo Lee, Jung-Woo Lee, Tula R Paudel, Long-Qing Chen, Evgeny Y Tsymbal, Vitaly Alexandrov, Chang-Beom Eom, Alexei Gruverman
Strontium titanate (SrTiO3) is the "silicon" in the emerging field of oxide electronics. While bulk properties of this material have been studied for decades, new unexpected phenomena have recently been discovered at the nanoscale, when SrTiO3 forms an ultrathin film or an atomically-sharp interface with other materials. One of the striking discoveries is room-temperature ferroelectricity in strain-free ultrathin films of SrTiO3 driven by the TiSr antisite defects, which generate a local dipole moment polarizing the surrounding nanoregion...
December 13, 2017: Nano Letters
Elliot Padgett, Robert Hovden, Jessica C DaSilva, Barnaby D A Levin, John L Grazul, Tobias Hanrath, David A Muller
Electron tomography has become a valuable and widely used tool for studying the three-dimensional nanostructure of materials and biological specimens. However, the incomplete tilt range provided by conventional sample holders limits the fidelity and quantitative interpretability of tomographic images by leaving a "missing wedge" of unknown information in Fourier space. Imaging over a complete range of angles eliminates missing wedge artifacts and dramatically improves tomogram quality. Full-range tomography is usually accomplished using needle-shaped samples milled from bulk material with focused ion beams, but versatile specimen preparation methods for nanoparticles and other fine powders are lacking...
December 11, 2017: Microscopy and Microanalysis
Lazaros Andronis, Ilias Goranitis, Sue Bayliss, Rui Duarte
BACKGROUND: Metastatic cancers occur when cancer cells break away from the primary tumour. One of the most common sites of metastasis is the bone, with several therapeutic options currently available for managing bone metastases. In a resource-constrained environment, policy makers and practitioners need to know which options are cost effective. OBJECTIVE: The aim of this systematic review was to review and appraise published economic evaluations on treatments for the management of bone metastases...
December 9, 2017: PharmacoEconomics
Delin Cheng, Qingfei Liang, Yonggang Li, Jiahui Fan, Guocheng Wang, Haobo Pan, Changshun Ruan
Although heterogeneous bone scaffolds have shown potential in bone defect repair, their capability of aiding bone regeneration need to be further enhanced. Strontium, one important trace element in bone, has a well-known favorable effect on bone repair. Here a strontium containing scaffold (CPB/PCL/Sr) based on superficially porous calcined porcine bone (CPB) was obtained straightforwardly by sequential coating of SrCl2 and polycaprolactone (PCL). The basic characterization revealed that PCL coating could simultaneously improve the mechanical properties and, more importantly, restrain strontium release...
December 2, 2017: Colloids and Surfaces. B, Biointerfaces
Seemun Ray, Ulrich Thormann, Marlen Eichelroth, Matthäus Budak, Christoph Biehl, Markus Rupp, Ursula Sommer, Thaqif El Khassawna, Francisca I Alagboso, Marian Kampschulte, Marcus Rohnke, Anja Henß, Klaus Peppler, Vanessa Linke, Peter Quadbeck, Axel Voigt, Florian Stenger, Daniel Karl, Reinhard Schnettler, Christian Heiss, Katrin S Lips, Volker Alt
The purpose of this work was to investigate new bone formation in macroporous iron foams coated with strontium (FeSr) or bisphosphonate (FeBiP) compared to plain iron foam (Fe) and empty defect in a critical size metaphyseal bone defect model in ovariectomized rats. 60 female rats were subjected to bilateral ovariectomy and multi-deficient diet for 3 months. A 4 mm wedge shaped metaphyseal osteotomy was created, fixed with a mini-plate and subsequently filled with Fe, FeSr, FeBiP or left empty. After 6 weeks, μCt analysis revealed a statistically significant increased bone formation at the implant interface in FeSr compared to FeBiP (p = 0...
December 1, 2017: Biomaterials
Kasım Durmuş, Nergiz Hacer Turgut, Mehtap Doğan, Ersin Tuncer, Hatice Özer, Emine Elif Altuntaş, Melih Akyol
BACKGROUND: Mandibular fractures are the most common facial fractures. They can be treated by conservative techniques or by surgery. The authors hypothesized that the application of a single local dose of strontium chloride would accelerate the healing of subcondylar mandibular fractures, shorten the recovery time and prevent complications. OBJECTIVES: The aim of the present pilot study was to evaluate the effects of a single local dose of strontium chloride on the healing of subcondylar mandibular fractures in rats...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Xinmao Yin, Chi Sin Tang, Muhammad Aziz Majidi, Peng Ren, Le Wang, Ping Yang, Caozheng Diao, Xiaojiang Yu, Mark B H Breese, Andrew Thye Shen Wee, Junling Wang, Andrivo Rusydi
Hole-doped perovskite manganites have attracted much attention because of their unique optical, electronic and magnetic properties induced by the interplay between spin, charge, orbital and lattice degrees of freedom. Here, a comprehensive investigation of the optical, electronic and magnetic properties of La0.7Sr0.3MnO3 thin-films on SrTiO3 (LSMO/STO) and other substrates is conducted using a combination of temperature-dependent transport, spectroscopic ellipsometry, X-ray absorption spectroscopy and X-ray magnetic circular dichroism...
December 6, 2017: ACS Applied Materials & Interfaces
B Kullmann, M Hempel, R Thiel
This study presents a new chemical double-marking technique for European glass eels Anguilla anguilla by combing alizarin red S (ARS) and strontium chloride hexahydrate (Sr). Marked eels (double marked with ARS and Sr, but also single marked with ARS) were exposed in situ to brackish water (15 g l-1 artificial sea salt) for 14 days and did not exhibit increased mortalities compared with unmarked eels. Indeed, no mortality occurred in a marked group during the experiments. Moreover, an efficient mass-marking approach with low handling effort for both single ARS and double ARS-Sr techniques is described and was proven to be practicable for large-scale stocking programmes...
December 4, 2017: Journal of Fish Biology
Alejandro Valderrama, Radamés Reynoso, Raúl W Gómez, Manuel Quintana, Martín Romero
First principles calculations have been performed for C60@C180 carbon double-layer endofullerenes with up to: three diatomic radioiodine molecules (131I2), two potassium radio-iodide (K131I), and three sodium radio-iodide (Na131I) inside. The plane-wave pseudopotential (PP) method within the general gradient approximation (GGA) in the framework of the density functional theory (DFT) and time-dependent DFT (TD-DFT) was used to perform geometric optimizations (GOs) and molecular dynamics (MD) at 310 K and atmospheric pressure...
December 4, 2017: Journal of Molecular Modeling
E Martín-Merino, I Petersen, S Hawley, A Álvarez-Gutierrez, S Khalid, A Llorente-Garcia, A Delmestri, M K Javaid, T P Van Staa, A Judge, C Cooper, D Prieto-Alhambra
The venous thromboembolism risk among anti-osteoporotics is unknown. In this primary care study, the risk with other bisphosphonates [1.05 (0.94-1.18) and 0.96 (0.78-1.18)], strontium [0.90 (0.61-1.34) and 1.19 (0.82-1.74)], in the UK and Spain respectively, and denosumab [1.77 (0.25-12.66)] and teriparatide [1.27 (0.59-2.71)] in Spain, did not differ versus alendronate. INTRODUCTION: Most of the known adverse drug reactions described for anti-osteoporosis medication (AOM) have been described in studies comparing AOM users to non-users...
December 3, 2017: Osteoporosis International
D Nancy, N Rajendran
The obstacles faced to treat chronic osteomyelitis infection clinically led to the search for an ideal biomaterial, resulted in combining two major aspects of bone tissue engineering namely surface modified metallic implant and polymer nanocomposite scaffold. In the present study Gelatin - Strontium incorporated Hydroxyapatite (SrHAP) forming HG scaffold, vancomycin loaded chitosan -gelatin polyelectrolyte complex incorporated gelatin-SrHAP, forming HV scaffolds (HV1-0.5wt% and HV2-1wt% vancomycin) were investigated...
November 29, 2017: International Journal of Biological Macromolecules
Chunlin Chen, Deqiang Yin, Kazutoshi Inoue, Frank Lichtenberg, Xiuliang Ma, Yuichi Ikuhara, Johannes Georg Bednorz
The quasi-one-dimensional (1D) metallic conductivity of the perovskite-related SrnNbnO3n+2 compounds is of continuing fundamental physical interest as well as being important for developing advanced electronic devices. The SrnNbnO3n+2 compounds can be derived by introducing additional oxygen into the SrNbO3 perovskite. However, the physical origin for the transition of electrical properties from the three-dimensional (3D) isotropic conductivity in SrNbO3 to the quasi-1D metallic conductivity in SrnNbnO3n+2 requires more in-depth clarification...
November 30, 2017: ACS Nano
Lars Brinkmann, David J Rowan
Several cesium and strontium bioaccumulation models are used widely in national and international guidance for ecological and human health risk assessments for radiocesium (134Cs and 137Cs) and radiostrontium (90Sr), but have not been used to make predictions of radiological risk from nuclear accidents under variable environmental conditions on broad geographical scales. In this paper, we first present models for predicting the bioaccumulation of cesium and strontium by aquatic biota based on ambient concentrations of dissolved potassium and calcium, respectively, and then test these models using independent data from aquatic ecosystems at Canadian nuclear sites...
November 29, 2017: Ambio
Aleksandra Laskus, Joanna Kolmas
Calcium phosphate materials (CaPs) are similar to inorganic part of human mineralized tissues (i.e., bone, enamel, and dentin). Owing to their high biocompatibility, CaPs, mainly hydroxyapatite (HA), have been investigated for their use in various medical applications. One of the most widely used ways to improve the biological and physicochemical properties of HA is ionic substitution with trace ions. Recent developments in bioceramics have already demonstrated that introducing foreign ions is also possible in other CaPs, such as tricalcium phosphates (amorphous as well as α and β crystalline forms) and brushite...
November 27, 2017: International Journal of Molecular Sciences
Praveen Kumar Sekhar, Zachary Moore, Shyam Aravamudhan, Ajit Khosla
In this article, a new investigation on a low-temperature electrochemical hydrocarbon and NOx sensor is presented. Based on the mixed-potential-based sensing scheme, the sensor is constructed using platinum and metal oxide electrodes, along with an Yttria-Stabilized Zirconia (YSZ)/Strontium Titanate (SrTiO₃) thin-film electrolyte. Unlike traditional mixed-potential sensors which operate at higher temperatures (>400 °C), this potentiometric sensor operates at 200 °C with dominant hydrocarbon (HC) and NOx response in the open-circuit and biased modes, respectively...
November 29, 2017: Sensors
Tibor Görögh, Elgar S Quabius, Alexander Georgitsis, Markus Hoffmann, Sebastian Lippross
BACKGROUND: Oscarvit (OSC) is an in-house preparation consisting of calcium, magnesium, phosphorus, strontium, Vitamin D, and eggshell membrane hydrolysate containing naturally occurring glycosaminoglycans and sulfated glycoproteins. OSC has been used both in an open-label human study and in vitro in osteoblasts. METHODS: Fifteen patients divided into three groups received oral OSC 0.6 g three times daily for 20 days. The main outcome measures were regional skeletal pain over the treatment period...
November 28, 2017: BMC Musculoskeletal Disorders
Ramya Nair, Shahin Aboobacker, Srinivas Mutalik, Guruprasad Kalthur, Satish Kumar Adiga
Parthenotes are characterized by poor in vitro developmental potential either due to the ploidy status or the absence of paternal factors. In the present study, we demonstrate the beneficial role of sperm-derived factors (SDF) on the in vitro development of mouse parthenotes. Mature (MII) oocytes collected from superovulated Swiss albino mice were activated using strontium chloride (SrCl2) in the presence or absence of various concentrations of SDF in M16 medium. The presence of SDF in activation medium did not have any significant influence on the activation rate...
November 28, 2017: Zygote: the Biology of Gametes and Early Embryos
Nathan J Beal, Thomas A Corry, Patrick J O'Malley
A comparison between experimental and Broken Symmetry Density Functional Theory (BS-DFT) calculated hyperfine couplings for the S2 state of the oxygen evolving complex (OEC) has been performed. The effect of Ca substitution by Sr combined with the protonation state of two terminal hydroxo or water ligands, W1 and W2, on the calculated hyperfine couplings of 55Mn, 13C, 14N, 17O and 1H nuclei has been investigated. Our findings show best agreement for OEC models which contain a hydroxo group at the W2 position and a water molecule at W1...
November 27, 2017: Journal of Physical Chemistry. B
Christiane de Melo Alencar, Ranna Castro da Silva, Jusuína Lamartine Nogueira Araújo, Ana Daniela Silva da Silveira, Cecy Martins Silva
PURPOSE: To evaluate the effect of 5% potassium nitrate containing 2% sodium fluoride and 10% strontium chloride on tooth sensitivity and color change after at-home bleaching treatment across 3 months of follow-up. METHODS: 60 subjects were randomly allocated by numerical draw into three groups (n= 20): (1) Control, treated with 22% carbamide peroxide (CP) followed by application of a toothpaste without active ingredient: (2) Nitrate, treated with 22% CP followed by application of a toothpaste containing 5% potassium nitrate and 2% sodium fluoride: (3) Strontium, treated with 22% CP followed by application of a toothpaste containing 10% strontium chloride...
October 2017: American Journal of Dentistry
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"